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Aliases for TDGF1P3 Gene

Aliases for TDGF1P3 Gene

  • Teratocarcinoma-Derived Growth Factor 1 Pseudogene 3 2 3 4
  • Teratocarcinoma-Derived Growth Factor 3, Pseudogene 2 3
  • CRIPTO3 3 4
  • TDGF3 3 4
  • TDGF2 3 4
  • Teratocarcinoma-Derived Growth Factor 2 (Retroposin, Possibly Expressed) 3
  • Epidermal Growth Factor-Like Cripto Protein CR3 4
  • Teratocarcinoma-Derived Growth Factor-2 3
  • Cripto-3 Growth Factor 4
  • CRIPTO-3 3
  • CRIPTO 3
  • TDGF1 3
  • CR-3 3

External Ids for TDGF1P3 Gene

Previous HGNC Symbols for TDGF1P3 Gene

  • TDGF3

Previous GeneCards Identifiers for TDGF1P3 Gene

  • GC0XP109765

Summaries for TDGF1P3 Gene

Entrez Gene Summary for TDGF1P3 Gene

  • The TDGF3 locus has characteristics of a retrotransposon, including lack of introns and a poly(A) sequence. [provided by RefSeq, Jul 2008]

GeneCards Summary for TDGF1P3 Gene

TDGF1P3 (Teratocarcinoma-Derived Growth Factor 1 Pseudogene 3) is a Pseudogene. Diseases associated with TDGF1P3 include teratocarcinoma. Among its related pathways are L1CAM interactions and NF-KappaB Family Pathway. GO annotations related to this gene include growth factor activity.

UniProtKB/Swiss-Prot for TDGF1P3 Gene

  • Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Activates the Nodal-dependent signaling pathway.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TDGF1P3 Gene

Genomics for TDGF1P3 Gene

Genomic Location for TDGF1P3 Gene

Start:
110,520,312 bp from pter
End:
110,523,021 bp from pter
Size:
2,710 bases
Orientation:
Plus strand

Genomic View for TDGF1P3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TDGF1P3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TDGF1P3 Gene

No data available for Regulatory Elements for TDGF1P3 Gene

Proteins for TDGF1P3 Gene

  • Protein details for TDGF1P3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P51864-TDGF3_HUMAN
    Recommended name:
    Putative teratocarcinoma-derived growth factor 3
    Protein Accession:
    P51864
    Secondary Accessions:

    Protein attributes for TDGF1P3 Gene

    Size:
    188 amino acids
    Molecular mass:
    21181 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TDGF1P3 Gene

Proteomics data for TDGF1P3 Gene at MOPED

Post-translational modifications for TDGF1P3 Gene

No data available for DME Specific Peptides for TDGF1P3 Gene

Domains for TDGF1P3 Gene

Protein Domains for TDGF1P3 Gene

Graphical View of Domain Structure for InterPro Entry

P51864

UniProtKB/Swiss-Prot:

TDGF3_HUMAN :
  • P51864
Domain:
  • Contains 1 EGF-like domain.
genes like me logo Genes that share domains with TDGF1P3: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for TDGF1P3 Gene

Function for TDGF1P3 Gene

Molecular function for TDGF1P3 Gene

UniProtKB/Swiss-Prot Function: Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Activates the Nodal-dependent signaling pathway.

Gene Ontology (GO) - Molecular Function for TDGF1P3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008083 growth factor activity NAS 1882841
genes like me logo Genes that share ontologies with TDGF1P3: view

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TDGF1P3 Gene

Localization for TDGF1P3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TDGF1P3 Gene

Cell membrane.

Gene Ontology (GO) - Cellular Components for TDGF1P3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
GO:0009279 cell outer membrane IDA 18835250
genes like me logo Genes that share ontologies with TDGF1P3: view

No data available for Subcellular locations from COMPARTMENTS for TDGF1P3 Gene

Pathways for TDGF1P3 Gene

genes like me logo Genes that share pathways with TDGF1P3: view

Pathways by source for TDGF1P3 Gene

1 Sino Biological pathway for TDGF1P3 Gene
2 Cell Signaling Technology pathways for TDGF1P3 Gene
1 BioSystems pathway for TDGF1P3 Gene

Interacting Proteins for TDGF1P3 Gene

Gene Ontology (GO) - Biological Process for TDGF1P3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction IDA 18835250
genes like me logo Genes that share ontologies with TDGF1P3: view

Compounds for TDGF1P3 Gene

(2) Novoseek inferred chemical compound relationships for TDGF1P3 Gene

Compound -log(P) Hits PubMed IDs
retinoic acid 15.4 4
agar 14.2 3
genes like me logo Genes that share compounds with TDGF1P3: view

Transcripts for TDGF1P3 Gene

mRNA/cDNA for TDGF1P3 Gene

(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TDGF1P3 Gene

Teratocarcinoma-derived growth factor 1 pseudogene 3:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TDGF1P3

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TDGF1P3
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TDGF1P3 Gene

No ASD Table

Relevant External Links for TDGF1P3 Gene

GeneLoc Exon Structure for
TDGF1P3
ECgene alternative splicing isoforms for
TDGF1P3

Expression for TDGF1P3 Gene

mRNA expression in normal human tissues for TDGF1P3 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TDGF1P3 Gene

This gene is overexpressed in Kidney - Cortex (9.4), Spleen (8.1), Adrenal Gland (5.4), and Ovary (5.1).

SOURCE GeneReport for Unigene cluster for TDGF1P3 Gene Hs.592361

mRNA Expression by UniProt/SwissProt for TDGF1P3 Gene

P51864-TDGF3_HUMAN
Tissue specificity: Expressed weakly in lung, colon and breast. Expressed also strongly in primary cancer tissues; lung and colon cancers.
genes like me logo Genes that share expressions with TDGF1P3: view

In Situ Assay Products

No data available for Protein expression for TDGF1P3 Gene

Orthologs for TDGF1P3 Gene

Evolution for TDGF1P3 Gene

ENSEMBL:
Gene Tree for TDGF1P3 (if available)
TreeFam:
Gene Tree for TDGF1P3 (if available)

No data available for Orthologs for TDGF1P3 Gene

Paralogs for TDGF1P3 Gene

Selected SIMAP similar genes for TDGF1P3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TDGF1P3: view

No data available for Paralogs for TDGF1P3 Gene

Variants for TDGF1P3 Gene

Sequence variations from dbSNP and Humsavar for TDGF1P3 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs5942642 -- 110,521,988(+) tctca(C/T)tctgt nc-transcript-variant
rs5942952 -- 110,518,366(+) ATGAG(A/T)AAACA upstream-variant-2KB
rs5942953 -- 110,518,622(+) AAATC(A/C)CAGTC upstream-variant-2KB
rs5942954 -- 110,519,892(+) TCTGG(C/G)GTAAC upstream-variant-2KB
rs5942955 -- 110,520,375(+) TGTCT(C/G)CCCGT nc-transcript-variant

Relevant External Links for TDGF1P3 Gene

HapMap Linkage Disequilibrium report
TDGF1P3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TDGF1P3 Gene

Disorders for TDGF1P3 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for TDGF1P3 Gene including...

Search for TDGF1P3 Gene in MalaCards »

(16) Novoseek inferred disease relationships for TDGF1P3 Gene

Disease -log(P) Hits PubMed IDs
teratocarcinoma 64.5 3
colorectal carcinoma 52.2 5
colon carcinoma 50.1 2
carcinoma embryonal 46.1 7
colorectal tumors 45.3 1
genes like me logo Genes that share disorders with TDGF1P3: view

No data available for UniProtKB/Swiss-Prot for TDGF1P3 Gene

Publications for TDGF1P3 Gene

  1. CRIPTO3, a presumed pseudogene, is expressed in cancer. (PMID: 18835250) Sun C. … Carulli J.P. (Biochem. Biophys. Res. Commun. 2008) 3 4 23
  2. Isolation and characterization of the CRIPTO autosomal gene and its X-linked related sequence. (PMID: 1882841) Dono R. … Persico M.G. (Am. J. Hum. Genet. 1991) 2 3 4
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  4. Germ cell nuclear factor is a repressor of CRIPTO-1 and CRIPTO-3. (PMID: 16954206) Hentschke M. … HA1bner C.A. (J. Biol. Chem. 2006) 3
  5. TDGF1 is a novel predictive marker for metachronous metastasis of colorectal cancer. (PMID: 20126975) Miyoshi N. … Mori M. (Int. J. Oncol. 2010) 23

Products for TDGF1P3 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate TDGF1P3
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TDGF1P3
    • Block miRNA regulation of TDGF1P3 using miScript Target Protectors

    Sources for TDGF1P3 Gene

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