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Aliases for TDGF1P3 Gene

Aliases for TDGF1P3 Gene

  • Teratocarcinoma-Derived Growth Factor 1 Pseudogene 3 2 3 4 5
  • Teratocarcinoma-Derived Growth Factor 3, Pseudogene 2 3
  • CRIPTO3 3 4
  • TDGF2 3 4
  • TDGF3 3 4
  • Teratocarcinoma-Derived Growth Factor 2 (Retroposin, Possibly Expressed) 3
  • Epidermal Growth Factor-Like Cripto Protein CR3 4
  • Teratocarcinoma-Derived Growth Factor-2 3
  • Cripto-3 Growth Factor 4
  • CRIPTO-3 3
  • CRIPTO 3
  • TDGF1 3
  • CR-3 3

External Ids for TDGF1P3 Gene

Previous HGNC Symbols for TDGF1P3 Gene

  • TDGF3

Previous GeneCards Identifiers for TDGF1P3 Gene

  • GC0XP109765

Summaries for TDGF1P3 Gene

Entrez Gene Summary for TDGF1P3 Gene

  • The TDGF3 locus has characteristics of a retrotransposon, including lack of introns and a poly(A) sequence. [provided by RefSeq, Jul 2008]

GeneCards Summary for TDGF1P3 Gene

TDGF1P3 (Teratocarcinoma-Derived Growth Factor 1 Pseudogene 3) is a Pseudogene. Diseases associated with TDGF1P3 include teratocarcinoma. GO annotations related to this gene include growth factor activity.

UniProtKB/Swiss-Prot for TDGF1P3 Gene

  • Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Activates the Nodal-dependent signaling pathway.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TDGF1P3 Gene

Genomics for TDGF1P3 Gene

Regulatory Elements for TDGF1P3 Gene

Enhancers for TDGF1P3 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TDGF1P3 on UCSC Golden Path with GeneCards custom track

Genomic Location for TDGF1P3 Gene

Chromosome:
X
Start:
110,520,312 bp from pter
End:
110,523,021 bp from pter
Size:
2,710 bases
Orientation:
Plus strand

Genomic View for TDGF1P3 Gene

Genes around TDGF1P3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TDGF1P3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TDGF1P3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TDGF1P3 Gene

Proteins for TDGF1P3 Gene

  • Protein details for TDGF1P3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P51864-TDGF3_HUMAN
    Recommended name:
    Putative teratocarcinoma-derived growth factor 3
    Protein Accession:
    P51864

    Protein attributes for TDGF1P3 Gene

    Size:
    188 amino acids
    Molecular mass:
    21181 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TDGF1P3 Gene

Proteomics data for TDGF1P3 Gene at MOPED

Post-translational modifications for TDGF1P3 Gene

No data available for DME Specific Peptides for TDGF1P3 Gene

Domains & Families for TDGF1P3 Gene

Protein Domains for TDGF1P3 Gene

Suggested Antigen Peptide Sequences for TDGF1P3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P51864

UniProtKB/Swiss-Prot:

TDGF3_HUMAN :
  • Contains 1 EGF-like domain.
Domain:
  • Contains 1 EGF-like domain.
genes like me logo Genes that share domains with TDGF1P3: view

No data available for Gene Families for TDGF1P3 Gene

Function for TDGF1P3 Gene

Molecular function for TDGF1P3 Gene

UniProtKB/Swiss-Prot Function:
Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm. Activates the Nodal-dependent signaling pathway.

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TDGF1P3 Gene

Localization for TDGF1P3 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TDGF1P3 Gene

Cell membrane.

Gene Ontology (GO) - Cellular Components for TDGF1P3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane IEA --
genes like me logo Genes that share ontologies with TDGF1P3: view

No data available for Subcellular locations from COMPARTMENTS for TDGF1P3 Gene

Pathways & Interactions for TDGF1P3 Gene

SuperPathways for TDGF1P3 Gene

No Data Available

Interacting Proteins for TDGF1P3 Gene

Gene Ontology (GO) - Biological Process for TDGF1P3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TDGF1P3 Gene

Drugs & Compounds for TDGF1P3 Gene

(2) Additional Compounds for TDGF1P3 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with TDGF1P3: view

Transcripts for TDGF1P3 Gene

mRNA/cDNA for TDGF1P3 Gene

(2) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TDGF1P3 Gene

Teratocarcinoma-derived growth factor 1 pseudogene 3:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TDGF1P3 Gene

No ASD Table

Relevant External Links for TDGF1P3 Gene

GeneLoc Exon Structure for
TDGF1P3
ECgene alternative splicing isoforms for
TDGF1P3

Expression for TDGF1P3 Gene

mRNA expression in normal human tissues for TDGF1P3 Gene

mRNA differential expression in normal tissues according to GTEx for TDGF1P3 Gene

This gene is overexpressed in Kidney - Cortex (x9.4), Spleen (x8.1), Adrenal Gland (x5.4), and Ovary (x5.1).

SOURCE GeneReport for Unigene cluster for TDGF1P3 Gene Hs.592361

mRNA Expression by UniProt/SwissProt for TDGF1P3 Gene

P51864-TDGF3_HUMAN
Tissue specificity: Expressed weakly in lung, colon and breast. Expressed also strongly in primary cancer tissues; lung and colon cancers.
genes like me logo Genes that share expression patterns with TDGF1P3: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for TDGF1P3 Gene

Orthologs for TDGF1P3 Gene

Evolution for TDGF1P3 Gene

ENSEMBL:
Gene Tree for TDGF1P3 (if available)
TreeFam:
Gene Tree for TDGF1P3 (if available)

No data available for Orthologs for TDGF1P3 Gene

Paralogs for TDGF1P3 Gene

(1) SIMAP similar genes for TDGF1P3 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TDGF1P3: view

No data available for Paralogs for TDGF1P3 Gene

Variants for TDGF1P3 Gene

Sequence variations from dbSNP and Humsavar for TDGF1P3 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs747670876 -- 110,518,504(+) TGACA(C/T)CGCTT upstream-variant-2KB
rs747864329 -- 110,522,187(+) ACTCC(A/T)GACCT nc-transcript-variant
rs748891054 -- 110,522,827(+) GTGAT(C/G)AAACT nc-transcript-variant
rs749047839 -- 110,521,370(+) ACAGA(A/T)CCTGC nc-transcript-variant
rs749916106 -- 110,521,258(+) GGAGA(C/T)CTGGC nc-transcript-variant

Relevant External Links for TDGF1P3 Gene

HapMap Linkage Disequilibrium report
TDGF1P3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TDGF1P3 Gene

Disorders for TDGF1P3 Gene

MalaCards: The human disease database

(1) MalaCards diseases for TDGF1P3 Gene - From: Novoseek and GeneCards

Disorder Aliases PubMed IDs
teratocarcinoma
  • mixed embryonal carcinoma and teratoma
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for TDGF1P3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TDGF1P3
genes like me logo Genes that share disorders with TDGF1P3: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TDGF1P3 Gene

Publications for TDGF1P3 Gene

  1. Isolation and characterization of the CRIPTO autosomal gene and its X-linked related sequence. (PMID: 1882841) Dono R. … Persico M.G. (Am. J. Hum. Genet. 1991) 2 3 4 67
  2. CRIPTO3, a presumed pseudogene, is expressed in cancer. (PMID: 18835250) Sun C. … Carulli J.P. (Biochem. Biophys. Res. Commun. 2008) 3 23
  3. TDGF1 is a novel predictive marker for metachronous metastasis of colorectal cancer. (PMID: 20126975) Miyoshi N. … Mori M. (Int. J. Oncol. 2010) 23
  4. Germ cell nuclear factor is a repressor of CRIPTO-1 and CRIPTO-3. (PMID: 16954206) Hentschke M. … HA1bner C.A. (J. Biol. Chem. 2006) 3
  5. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3

Products for TDGF1P3 Gene

Sources for TDGF1P3 Gene

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