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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TCTN3 Gene

protein-coding   GIFtS: 50
GCID: GC10M097414

Tectonic Family Member 3

(Previous name: chromosome 10 open reading frame 61)
(Previous symbol: C10orf61)
Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tectonic Family Member 31 2     JBTS182
C10orf611 2 3     OFD42
TECT32 3     tectonic-32
Chromosome 10 Open Reading Frame 611     

External Ids:    HGNC: 245191   Entrez Gene: 261232   Ensembl: ENSG000001199777   OMIM: 6138475   UniProtKB: Q6NUS63   

Export aliases for TCTN3 gene to outside databases

Previous GC identifer: GC10M091050


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TCTN3 Gene:
This gene encodes a member of the tectonic gene family which functions in Hedgehog signal transduction and
development of the neural tube. Mutations in this gene have been associated with Orofaciodigital Syndrome IV and
Joubert Syndrom 18. Alternatively spliced transcript variants encoding multiple isoforms have been observed for
this gene. (provided by RefSeq, Sep 2012)

GeneCards Summary for TCTN3 Gene: 
TCTN3 (tectonic family member 3) is a protein-coding gene. Diseases associated with TCTN3 include orofaciodigital syndrome, and oral-facial-digital syndrome type 4. An important paralog of this gene is TCTN1.

UniProtKB/Swiss-Prot: TECT3_HUMAN, Q6NUS6
Function: Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate
ciliary membrane composition (By similarity). May be involved in apoptosis regulation. Necessary for signal
transduction through the sonic hedgehog (Shh) signaling pathway




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NT_030059.13  NC_018921.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TCTN3 gene promoter:
         SRF   GATA-3   SRF (504 AA)   MEF-2   Brachyury   CUTL1   GATA-1   E47   MEF-2A   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTCTN3 promoter sequence
   Search SABiosciences Chromatin IP Primers for TCTN3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCTN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.1   Ensembl cytogenetic band:  10q24.1   HGNC cytogenetic band: 10q23.33

TCTN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCTN3 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M097414:  view genomic region     (about GC identifiers)

Start:
97,423,153 bp from pter      End:
97,453,900 bp from pter
Size:
30,748 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TECT3_HUMAN, Q6NUS6 (See protein sequence)
Recommended Name: Tectonic-3 precursor  
Size: 607 amino acids; 66157 Da
Subunit: Part of the tectonic-like complex (also named B9 complex) (By similarity)
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Sequence caution: Sequence=AAH68449.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=ABB90564.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAC11567.1;
Type=Frameshift; Positions=238; Sequence=BAC87634.1; Type=Erroneous initiation; Note=Translation N-terminally
shortened; Sequence=CAI16768.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A6NIC8 B0QZ90 B4DR81 Q6P7P3 Q6UW27 Q6ZQQ0 Q8N7K1 Q8NBQ0 Q96GF7 Q9Y3U1
Alternative splicing: 5 isoforms:  Q6NUS6-1   Q6NUS6-2   Q6NUS6-3   Q6NUS6-4   Q6NUS6-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TCTN3: NX_Q6NUS6

Explore proteomics data for TCTN3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6NUS6

  • TCTN3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TCTN3 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001137445.1  NP_056446.4  

    ENSEMBL proteins: 
     ENSP00000360261   ENSP00000360253   ENSP00000406621   ENSP00000265993   ENSP00000387567  

    Human Recombinant Protein Products for TCTN3: 
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    Cloud-Clone Corp. Proteins for TCTN3 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    TCTN3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TCTN: Tectonic proteins

    1 InterPro protein domain:
     IPR011677 DUF1619

    Graphical View of Domain Structure for InterPro Entry Q6NUS6

    ProtoNet protein and cluster: Q6NUS6

    UniProtKB/Swiss-Prot: TECT3_HUMAN, Q6NUS6
    Similarity: Belongs to the tectonic family


    TCTN3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TECT3_HUMAN, Q6NUS6
    Function: Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate
    ciliary membrane composition (By similarity). May be involved in apoptosis regulation. Necessary for signal
    transduction through the sonic hedgehog (Shh) signaling pathway

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    TCTN3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TCTN3:
     Decreased Wnt reporter activit 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TCTN3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TCTN3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TCTN3 
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    SwitchGear 3'UTR luciferase reporter plasmidTCTN3 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TCTN3

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--
    GO:0007224smoothened signaling pathway IMP--
    GO:0060271cilium morphogenesis ISS--

    TCTN3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TCTN3 (TECT3)

    Search CenterWatch for drugs/clinical trials and news about TCTN3 / TECT3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TCTN3 gene (2 alternative transcripts): 
    NM_001143973.1  NM_015631.5  

    Unigene Cluster for TCTN3:

    Tectonic family member 3
    Hs.438991  [show with all ESTs]
    Unigene Representative Sequence: AK128834
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371217 ENST00000371209(uc001kld.3) ENST00000424175 ENST00000497399
    ENST00000478245 ENST00000265993(uc001klb.4) ENST00000430368(uc010qoi.2)


    miRNA
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    3 QIAGEN miScript miRNA Assays for microRNAs that regulate TCTN3:
    hsa-miR-579 hsa-miR-4328 hsa-miR-449c*
    SwitchGear 3'UTR luciferase reporter plasmidTCTN3 3' UTR sequence
    Inhib. RNA
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                         Customized lentivirus expression plasmids for stable overexpression of TCTN3 
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TCTN3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TCTN3

    Additional mRNA sequence: 

    AK075357.1 AK128834.1 AK299141.1 AL050022.1 AY359022.1 BC009494.2 BC061582.1 BC068449.1 
    DQ278872.1 

    24/26 DOTS entries (see all 26):

    DT.100795314  DT.100723751  DT.100795315  DT.100795313  DT.80101860  DT.121262394  DT.100027070  DT.101984682 
    DT.121262475  DT.95159258  DT.121262626  DT.70101173  DT.100805088  DT.100795317  DT.121262430  DT.40125600 
    DT.40206293  DT.91798933  DT.92013965  DT.92017021  DT.92447851  DT.92447854  DT.95159257  DT.95159259 

    24/343 AceView cDNA sequences (see all 343):

    AA232141 AI281033 BM850724 AI868215 CD367745 Z39224 AI360030 BU159145 
    NM_015631 AK098295 AA622048 BI772642 CA426847 BM996004 AI090281 BX325417 
    BM728527 CR613495 BG106304 AI363208 AA463308 AA039653 BM744485 AA587227 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for TCTN3 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
    SP1:                                      -                                         -           -                                             
    SP2:                                      -                       -                             -                                             
    SP3:                                      -                                         -     -     -                                             
    SP4:                                      -     -                                                                                             
    SP5:                                                                                                                                          


    ECgene alternative splicing isoforms for TCTN3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TCTN3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCAGAGAGC
    TCTN3 Expression
    About this image


    See TCTN3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TCTN3

    SOURCE GeneReport for Unigene cluster: Hs.438991
        SABiosciences Custom PCR Arrays for TCTN3
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TCTN3 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tctn31 , 5 tectonic family member 31, 5 79.45(n)1
    73.65(a)1
      19 (34.25 cM)5
    675901  NM_026260.21  NP_080536.21 
     405964465 
    chicken
    (Gallus gallus)
    Aves LOC1008574121 tectonic-3-like 62.83(n)
    52.8(a)
      100857412  XM_003641533.1  XP_003641581.1 
    lizard
    (Anolis carolinensis)
    Reptilia TCTN36
    tectonic family member 3
    40(a)
    1 ↔ 1
    3(38038553-38054766)


    ENSEMBL Gene Tree for TCTN3 (if available)
    TreeFam Gene Tree for TCTN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TCTN3 gene
    TCTN12  
    1 SIMAP similar gene for TCTN3 using alignment to 2 protein entries:     TECT3_HUMAN (see all proteins):
    TCTN1

    TCTN3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/663 SNPs in TCTN3 are shown (see all 663)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0688234
    Joubert syndrome 18 (JBTS18)4--see VAR_0688232 G R mis40--------
    rs3733561521,2
    C--91067785(+) CAGCT-/CTTG  
     GAAGCAA
    CACTT
    2 -- int10--------
    rs106101571,2
    C--91067786(+) CAGCT-/CACTTTA 2 -- int10--------
    rs786747041,2
    C--91067791(+) CACTTG/TAAACA 2 -- int10--------
    rs745153751,2
    C--91067792(+) ACTTTA/GAACAA 2 -- int10--------
    rs778849961,2
    C--91067795(+) TTAAAC/GAAACA 2 -- int10--------
    rs758925701,2
    C--91067796(+) TAAACA/CAACAT 2 -- int10--------
    rs1434485271,2
    C--91068182(+) GGAAG-/AACACA 2 -- int10--------
    rs1115132701,2
    C,F--91068379(+) CCACAC/ACTAAT 2 -- int12Minor allele frequency- A:0.04CSA NA 122
    rs614000571,2
    C--91075856(+) AAAAA-/A/A   
      AAAAAA
    GAAAA
    2 -- int11NA 2

    HapMap Linkage Disequilibrium report for TCTN3 (97423153 - 97453900 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for TCTN3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2662211CNV Deletion23128226
    nsv526761CNV Loss19592680
    nsv526180CNV Gain19592680


    Human Gene Mutation Database (HGMD): TCTN3
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613847    OMIM disorders: --

    UniProtKB/Swiss-Prot: TECT3_HUMAN, Q6NUS6
  • Orofaciodigital syndrome 4 (OFD4) [MIM:258860]: A form of orofaciodigital syndrome, a group of
    heterogeneous disorders characterized by malformations of the oral cavity, face and digits, and associated
    phenotypic abnormalities that lead to the delineation of various subtypes. OFD4 patients have tongue nodules,
    multiple frenulae, broad flat nose, hypertelorism, and short rib polydactyly with tibial dysplasia (Majewski
    syndrome). The presence of severe tibial aplasia differentiates OFD4 from OFD1. Additional features of cystic
    dysplastic kidneys and brain malformation, including occipital encephalocele, are observed in severely affected
    patients. Note=The disease is caused by mutations affecting the gene represented in this entry
  • Joubert syndrome 18 (JBTS18) [MIM:614815]: A form of Joubert syndrome, a disorder presenting with
    cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay.
    Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented
    superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar
    tooth on transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy and renal
    disease. JBTS18 patients have vermis agenesis and the molar tooth sign as well as severe kyphoscoliosis. Other
    features include intrauterine growth retardation, oral anomalies, micrognathism, polydactyly and camptodactyly,
    joint laxity, horseshoe kidney, and ventricular septal defect. Note=The disease is caused by mutations affecting
    the gene represented in this entry. TCTN3-mutated fibroblasts from JBTS18 patients fail to respond to Shh
    agonists suggesting that at least some of the defects in affected individuals may be secondary to reduced Shh
    signaling (PubMed:22883145)

  • 17 diseases for TCTN3:    About MalaCards
    orofaciodigital syndrome    oral-facial-digital syndrome type 4    joubert syndrome 18    orofaciodigital syndrome 4
    occipital encephalocele    joubert syndrome    encephalocele    encephaloceles
    brain malformations    ventricular septal defect    polydactyly    apraxia
    cerebellar ataxia    hypotonia    ataxia    alzheimer's disease
    retinitis

    1 disease from the University of Copenhagen DISEASES database for TCTN3:
    Polydactyly

    TCTN3 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): TCTN3
    Human Genome Epidemiology (HuGE) Navigator: TCTN3 (1 document)

    Export disorders for TCTN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TCTN3 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with TCTN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (2003)
    2. TCTN3 mutations cause Mohr-Majewski syndrome. (PubMed id 22883145)1, 2 Thomas S.... Attie-Bitach T. (2012)
    3. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (2006)
    4. Tectonic, a novel regulator of the Hedgehog pathway required for both activation and inhibition. (PubMed id 16357211)1, 2 Reiter J.F. and Skarnes W.C. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    8. Proteomic identification of common SCF ubiquitin ligas e FBXO6-interacting glycoproteins in three kinds of cells. (PubMed id 22268729)1 Liu B....Wang L.S. (2012)
    9. Identification of novel regulators of apoptosis using a high- throughput cell-based screen. (PubMed id 17464193)2 Park K.M.... Kim S.J. (2007)
    10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26123 HGNC: 24519 AceView: C10orf61 Ensembl:ENSG00000119977 euGenes: HUgn26123
    ECgene: TCTN3 H-InvDB: TCTN3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TCTN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TCTN3 gene:
    Search GeneIP for patents involving TCTN3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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