TCTEX1D2 Gene
protein-coding GIFtS: 43
GCID: GC03M195975
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Tctex1 domain containing 2
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Aliases
for TCTEX1D2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Tctex1 Domain Containing 21 2 | | MGC332121 | | Tctex1 Domain-Containing Protein 22 |
Export aliases for TCTEX1D2 gene to outside databasesPrevious GC identifers: GC03M197502 GC03M193315 |
Summaries
for TCTEX1D2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TCTEX1D2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_029928.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TCTEX1D2 gene promoter:
Bach1 AML1a Lmo2 STAT5A Arnt Egr-2 AREB6 PPAR-alpha POU2F1 POU2F1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for TCTEX1D2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCTEX1D2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q29 Ensembl cytogenetic band: 3q29 HGNC cytogenetic band: 3q29TCTEX1D2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03M195975: view genomic region
(about GC identifiers)
Start:
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195,975,101 bp from pter |
End:
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196,045,170 bp from pter |
Size:
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70,070 bases |
Orientation:
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minus strand |
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Proteins
for TCTEX1D2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TC1D2_HUMAN, Q8WW35 (See
protein sequence)Recommended Name: Tctex1 domain-containing protein 2 Size: 142 amino acids; 16122 Da
Secondary accessions: A6NCN5Explore the universe of human proteins at neXtProt for TCTEX1D2: NX_Q8WW35
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8WW35
TCTEX1D2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_689986.2
ENSEMBL proteins: ENSP00000405181 ENSP00000415835 ENSP00000324323 ENSP00000410605
Human Recombinant Protein Products:
TCTEX1D2 Antibody Products:
Assay Products for TCTEX1D2: |
Protein
Domains /
Families
for TCTEX1D2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TCTEX1D2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q8WW35ProtoNet protein and cluster: Q8WW35 1 Blocks protein family: IPB005334 Tctex-1 family
UniProtKB/Swiss-Prot: TC1D2_HUMAN, Q8WW35Similarity: Belongs to the dynein light chain Tctex-type family |
Function
for TCTEX1D2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TCTEX1D2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TCTEX1D2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TCTEX1D2 (NM_152773) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TCTEX1D2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCTEX1D2 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- |
TCTEX1D2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for TCTEX1D2:
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Pathways & Interactions
for TCTEX1D2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TCTEX1D2
4 Interacting proteins for TCTEX1D2 (Q8WW351, 2, 3) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for TCTEX1D2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TCTEX1D2
Search CenterWatch for drugs/clinical trials and news about TCTEX1D2 / TC1D2
|
Transcripts
for TCTEX1D2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TCTEX1D2 gene: NM_152773.4 Unigene Cluster for TCTEX1D2: Tctex1 domain containing 2 Hs.733180 [show with all ESTs]Unigene Representative Sequence: BI8347746 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000431391 ENST00000491186 ENST00000465757 ENST00000426563 ENST00000325318
ENST00000446494(uc003fwi.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TCTEX1D2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TCTEX1D2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TCTEX1D2 (NM_152773) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TCTEX1D2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCTEX1D2 |
Additional cDNA sequence: BC015348.1 BC021177.2 NR_037950.1 5 DOTS entries: DT.409619 DT.75101948 DT.100745311 DT.40226400 DT.92419287 24/76 AceView cDNA sequences (see all 76): BM311591 AA642108 AW016718 BC015348 BX098544 CA950854 AI380016 CA772543 BX119411 BG168937 AI633800 AI419510 BM311000 CA848186 AA327608 BU633848 BE549966 BG490753 BG722153 BQ678650 CD368238 AA405635 CA771710 CA308507
GeneLoc Exon Structure
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Expression
for TCTEX1D2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TCTEX1D2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGAAATCTG
About this image
See TCTEX1D2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TCTEX1D2
SOURCE GeneReport for Unigene cluster: Hs.733180
SABiosciences Custom PCR Arrays for TCTEX1D2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TCTEX1D2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TCTEX1D2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TCTEX1D2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TCTEX1D2 |
Orthologs
for TCTEX1D2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TCTEX1D2 gene from 6/21 species (see all 21) About this table
ENSEMBL Gene Tree for TCTEX1D2 (if available)
TreeFam Gene Tree for TCTEX1D2 (if available) |
Paralogs
for TCTEX1D2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TCTEX1D2 gene
- TCTEX1D42 TCTE32 TCTEX1D12
14 SIMAP similar genes for TCTEX1D2 using alignment to 4 protein entries: TC1D2_HUMAN (see all proteins):TM4SF19 KIAA1651 FLJ16124 KIAA0101 SEC14L3 COQ5
GALK2 TUBA1C SH2B3 SNRPF PFKFB3 TCTEX1D1
TCTEX1D4 DYNLT1
TCTEX1D2 for paralogs About GeneDecksing
|
Genomic Variants
for TCTEX1D2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TCTEX1D2 (195975101 - 196045170 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for TCTEX1D2
1 CNV: 3472
2 Inversions: 37243 0568 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TCTEX1D2 |
|
Disorders
/ Diseases
for TCTEX1D2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 TCTEX1D2 for disorders About MalaCards
TCTEX1D2 for disorders About GeneDecksing
Human Genome Epidemiology (HuGE) Navigator: TCTEX1D2 (1 document)
Export disorders for TCTEX1D2 gene to outside databases
|
Publications
for TCTEX1D2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TCTEX1D2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TCTEX1D2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
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External Searches for TCTEX1D2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing TCTEX1D2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing TCTEX1D2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TCTEX1D2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TCTEX1D2 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for TCTEX1D2 gene:
Search GeneIP for patents involving TCTEX1D2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TCTEX1D2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TCTEX1D2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TCTEX1D2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TCTEX1D2 | | | OriGene Protein Over-expression Lysate for TCTEX1D2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TCTEX1D2 | | OriGene 3'-UTR Clone for TCTEX1D2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TCTEX1D2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TCTEX1D2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TCTEX1D2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TCTEX1D2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCTEX1D2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TCTEX1D2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TCTEX1D2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TCTEX1D2 |
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 | | | TCTEX1D2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  | | | | Search ThermoFisher Antibodies for TCTEX1D2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCTEX1D2 |
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