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TCTEX1D2 Gene

protein-coding   GIFtS: 42
GCID: GC03M196019

Tctex1 Domain Containing 2

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tctex1 Domain Containing 21 2
Tctex1 Domain-Containing Protein 22

External Ids:    HGNC: 284821   Entrez Gene: 2557582   Ensembl: ENSG000002131237   UniProtKB: Q8WW353   

Export aliases for TCTEX1D2 gene to outside databases

Previous GC identifers: GC03M197502 GC03M195975 GC03M193315


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TCTEX1D2 Gene:
TCTEX1D2 (Tctex1 domain containing 2) is a protein-coding gene. An important paralog of this gene is TCTEX1D4.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the TCTEX1D2 gene promoter:
         Bach1   AML1a   Lmo2   STAT5A   Arnt   Egr-2   AREB6   PPAR-alpha   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTCTEX1D2 promoter sequence
   Search Chromatin IP Primers for TCTEX1D2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TCTEX1D2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q29   Ensembl cytogenetic band:  3q29   HGNC cytogenetic band: 3q29

TCTEX1D2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCTEX1D2 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M196019:  view genomic region     (about GC identifiers)

Start:
196,018,090 bp from pter      End:
196,045,170 bp from pter
Size:
27,081 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TC1D2_HUMAN, Q8WW35 (See protein sequence)
Recommended Name: Tctex1 domain-containing protein 2  
Size: 142 amino acids; 16122 Da
Secondary accessions: A6NCN5

Explore the universe of human proteins at neXtProt for TCTEX1D2: NX_Q8WW35

Explore proteomics data for TCTEX1D2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TCTEX1D2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_689986.2  
    ENSEMBL proteins: 
     ENSP00000415835   ENSP00000324323   ENSP00000410605  

    TCTEX1D2 Human Recombinant Protein Products:

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    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TCTEX1D2

     
    Search eBioscience for Proteins for TCTEX1D2 

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    Novus Biologicals TCTEX1D2 Antibody
    Abcam antibodies for TCTEX1D2
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    ThermoFisher Antibodies for TCTEX1D2
    Search LSBio for Antibodies for TCTEX1D2

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    Cloud-Clone Corp. ELISAs for TCTEX1D2
    Cloud-Clone Corp. CLIAs for TCTEX1D2
    Search eBioscience for ELISAs for TCTEX1D2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR005334 Tctex

    Graphical View of Domain Structure for InterPro Entry Q8WW35

    ProtoNet protein and cluster: Q8WW35

    1 Blocks protein domain: IPB005334 Tctex-1 family

    UniProtKB/Swiss-Prot: TC1D2_HUMAN, Q8WW35
    Similarity: Belongs to the dynein light chain Tctex-type family


    Find genes that share domains with TCTEX1D2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with TCTEX1D2           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TCTEX1D2:
     Decreased influenza A virus in 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Tctex1d2):
     reproductive system 

    Find genes that share phenotypes with TCTEX1D2           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TCTEX1D2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TCTEX1D2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TCTEX1D2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TCTEX1D2

    miRNA
    Products:
        
    miRTarBase miRNAs that target TCTEX1D2:
    hsa-mir-133a-3p (MIRT021698)

    Block miRNA regulation of human, mouse, rat TCTEX1D2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TCTEX1D2
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TCTEX1D2

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: TCTEX1D2 (NM_152773)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TCTEX1D2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCTEX1D2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TCTEX1D2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCTEX1D2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    extracellular2
    mitochondrion1
    nucleus1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TCTEX1D2
    Interactions:

        Search GeneGlobe Interaction Network for TCTEX1D2

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    Selected Interacting proteins for TCTEX1D2 (Q8WW351, 2, 3 ENSP000003243234) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CSNK2BP678702, 3MINT-8253693 I2D: score=2 
    ENSG00000206406P678702, 3MINT-8253693 I2D: score=2 
    ENSG00000224398P678702, 3MINT-8253693 I2D: score=2 
    ENSG00000224774P678702, 3MINT-8253693 I2D: score=2 
    ENSG00000228875P678702, 3MINT-8253693 I2D: score=2 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TCTEX1D2 (TC1D2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TCTEX1D2 gene: 
    NM_152773.4  

    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000491186 ENST00000465757 ENST00000426563 ENST00000325318 ENST00000446494(uc003fwi.3)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TCTEX1D2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TCTEX1D2
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TCTEX1D2
    Predesigned siRNA for gene silencing in human, mouse, rat TCTEX1D2
    Clone
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    OriGene clones in human, mouse for TCTEX1D2 (see all 6)
    OriGene ORF clones in mouse, rat for TCTEX1D2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TCTEX1D2 (NM_152773)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TCTEX1D2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCTEX1D2
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TCTEX1D2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TCTEX1D2
      QuantiTect SYBR Green Assays in human, mouse, rat TCTEX1D2
      QuantiFast Probe-based Assays in human, mouse, rat TCTEX1D2

    Selected AceView cDNA sequences (see all 76):

    AA327608 BX119411 BC015348 BM311591 BU633848 AA642108 AI633800 CA772543 
    BX098544 AI380016 AW016718 BM311000 BE549966 CA950854 BG168937 CA848186 
    AI419510 BM808243 BG490753 AA807781 BE897067 AI218063 CK818899 CK005644 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TCTEX1D2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGAAATCTG
    TCTEX1D2 Expression
    About this image

    TCTEX1D2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TCTEX1D2 Protein Expression
        Custom PCR Arrays for TCTEX1D2
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat TCTEX1D2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCTEX1D2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TCTEX1D2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tctex1d21 , 5 Tctex1 domain containing 21, 5 85.45(n)1
    85.21(a)1
      16 (22.69 cM)5
    660611  NM_025329.31  NP_079605.11 
     324197025 
    chicken
    (Gallus gallus)
    Aves TCTEX1D21 Tctex1 domain containing 2 74.14(n)
    76.72(a)
      424914  XM_422724.3  XP_422724.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    71(a)
    1 → many
    AAWZ02039968(1222-4417)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tctex1d21 Tctex1 domain containing 2 71.51(n)
    76.07(a)
      100496772  XM_002934044.2  XP_002934090.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.187822 Transcribed sequence with weak similarity to protein more 73.56(n)    57058206 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG53596
    CG72766
    --
    27(a)
    27(a)
    many ↔ many
    many ↔ many
    3R(5825491-5826998)
    3L(15491302-15491921)
    worm
    (Caenorhabditis elegans)
    Secernentea dylt-26
    Protein DYLT-2 (dylt-2) mRNA, complete cds
    35(a)
    1 → many
    X(8939389-8940143) WBGene00017014


    ENSEMBL Gene Tree for TCTEX1D2 (if available)
    TreeFam Gene Tree for TCTEX1D2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TCTEX1D2 gene
    TCTEX1D42  TCTE32  ENSG000002727412  TCTEX1D12  
    14 SIMAP similar genes for TCTEX1D2 using alignment to 3 protein entries:     TC1D2_HUMAN (see all proteins):
    TM4SF19    KIAA1651    FLJ16124    SEC14L3    COQ5    GALK2
    TUBA1C    SH2B3    TM2D1    SNRPF    PFKFB3    TCTEX1D1
    TCTEX1D4    DYNLT1

    Find genes that share paralogs with TCTEX1D2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TCTEX1D2 (see all 526)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1895947401,2
    --193343730(+) TGGACG/TTGGAG 1 -- us2k10--------
    rs29481811,2
    C,H--193343736(+) TGGAGA/GCTTCC 1 -- us2k15Minor allele frequency- G:0.00EA NS NA 300
    rs732121751,2
    C,F--193343878(+) TCCTAC/TGAGCT 1 -- us2k12Minor allele frequency- T:0.09WA NA 238
    rs1171770121,2
    C,F--193343879(+) CCTACG/AAGCTC 1 -- us2k11Minor allele frequency- A:0.03EA 120
    rs67622721,2
    C,F,H--196017628(+) CCAGTG/ATAACA 1 -- int119Minor allele frequency- A:0.43EA NS NA CSA WA 2118
    rs1847810271,2
    --196017650(+) GGGCCA/GGGCGC 1 -- int10--------
    rs1875642051,2
    --196017653(+) CCGGGA/CGCAGT 1 -- int10--------
    rs1912879471,2
    --196017669(+) ACACCC/TGTAAT 1 -- int10--------
    rs585682671,2
    C,F--196017737(+) TCTGGC/TCAATA 1 -- int12Minor allele frequency- T:0.50NA 4
    rs597088581,2
    C,F--196017753(+) AAACCC/TCGTCT 1 -- int12Minor allele frequency- T:0.50NA 4

    HapMap Linkage Disequilibrium report for TCTEX1D2 (196018090 - 196045170 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for TCTEX1D2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2726576CNV Deletion23290073
    nsv4183CNV Loss18451855
    nsv878182CNV Loss21882294
    dgv5373n71CNV Gain21882294
    dgv5372n71CNV Gain21882294
    dgv1549e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TCTEX1D2
    DNA2.0 Custom Variant and Variant Library Synthesis for TCTEX1D2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with TCTEX1D2           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: TCTEX1D2 (1 document)

    Export disorders for TCTEX1D2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TCTEX1D2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TCTEX1D2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    2. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    3. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (Sci Signal 2012)
    4. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    5. A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PubMed id 20195357)1 Miyamoto-Sato E....Yanagawa H. (PLoS ONE 2010)
    6. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (Nature 2006)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 255758 HGNC: 28482 AceView: LOC116211 Ensembl:ENSG00000213123 euGenes: HUgn255758
    ECgene: TCTEX1D2 H-InvDB: TCTEX1D2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TCTEX1D2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TCTEX1D2 gene:
    Search GeneIP for patents involving TCTEX1D2

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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