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Aliases for TCTEX1D2 Gene

Aliases for TCTEX1D2 Gene

  • Tctex1 Domain Containing 2 2 3

External Ids for TCTEX1D2 Gene

Summaries for TCTEX1D2 Gene

GeneCards Summary for TCTEX1D2 Gene

TCTEX1D2 (Tctex1 Domain Containing 2) is a Protein Coding gene. An important paralog of this gene is ENSG00000272741.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCTEX1D2 Gene

Genomics for TCTEX1D2 Gene

Genomic Location for TCTEX1D2 Gene

Start:
196,291,219 bp from pter
End:
196,318,299 bp from pter
Size:
27,081 bases
Orientation:
Minus strand

Genomic View for TCTEX1D2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TCTEX1D2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCTEX1D2 Gene

Regulatory Elements for TCTEX1D2 Gene

Proteins for TCTEX1D2 Gene

  • Protein details for TCTEX1D2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8WW35-TC1D2_HUMAN
    Recommended name:
    Tctex1 domain-containing protein 2
    Protein Accession:
    Q8WW35
    Secondary Accessions:
    • A6NCN5

    Protein attributes for TCTEX1D2 Gene

    Size:
    142 amino acids
    Molecular mass:
    16122 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TCTEX1D2 Gene

Proteomics data for TCTEX1D2 Gene at MOPED

Post-translational modifications for TCTEX1D2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TCTEX1D2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TCTEX1D2 Gene

Domains for TCTEX1D2 Gene

Protein Domains for TCTEX1D2 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for TCTEX1D2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8WW35

UniProtKB/Swiss-Prot:

TC1D2_HUMAN
Family:
  • Belongs to the dynein light chain Tctex-type family.:
    • Q8WW35
genes like me logo Genes that share domains with TCTEX1D2: view

No data available for Gene Families for TCTEX1D2 Gene

Function for TCTEX1D2 Gene

Gene Ontology (GO) - Molecular Function for TCTEX1D2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20195357
genes like me logo Genes that share ontologies with TCTEX1D2: view

Phenotypes for TCTEX1D2 Gene

MGI mutant phenotypes for TCTEX1D2:
inferred from 1 alleles
GenomeRNAi human phenotypes for TCTEX1D2:
genes like me logo Genes that share phenotypes with TCTEX1D2: view

miRNA for TCTEX1D2 Gene

miRTarBase miRNAs that target TCTEX1D2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TCTEX1D2 Gene

Localization for TCTEX1D2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TCTEX1D2 Gene COMPARTMENTS Subcellular localization image for TCTEX1D2 gene
Compartment Confidence
cytosol 2
extracellular 2
mitochondrion 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TCTEX1D2 Gene

Pathways for TCTEX1D2 Gene

SuperPathways for TCTEX1D2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TCTEX1D2 Gene

None

No data available for Pathways by source for TCTEX1D2 Gene

Transcripts for TCTEX1D2 Gene

mRNA/cDNA for TCTEX1D2 Gene

Unigene Clusters for TCTEX1D2 Gene

Tctex1 domain containing 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TCTEX1D2 Gene

No ASD Table

Relevant External Links for TCTEX1D2 Gene

GeneLoc Exon Structure for
TCTEX1D2
ECgene alternative splicing isoforms for
TCTEX1D2

Expression for TCTEX1D2 Gene

mRNA expression in normal human tissues for TCTEX1D2 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TCTEX1D2 Gene

SOURCE GeneReport for Unigene cluster for TCTEX1D2 Gene Hs.733180

genes like me logo Genes that share expressions with TCTEX1D2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TCTEX1D2 Gene

Orthologs for TCTEX1D2 Gene

This gene was present in the common ancestor of animals.

Orthologs for TCTEX1D2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TCTEX1D2 35
  • 100 (n)
  • 100 (a)
TCTEX1D2 36
  • 100 (a)
OneToMany
cow
(Bos Taurus)
Mammalia TCTEX1D2 35
  • 91.13 (n)
  • 91.37 (a)
TCTEX1D2 36
  • 85 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 36
  • 96 (a)
ManyToMany
-- 36
  • 82 (a)
ManyToMany
TCTEX1D2 35
  • 93.97 (n)
  • 96.19 (a)
mouse
(Mus musculus)
Mammalia Tctex1d2 35
  • 85.45 (n)
  • 85.21 (a)
Tctex1d2 16
Tctex1d2 36
  • 84 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Tctex1d2 35
  • 86.85 (n)
  • 85.21 (a)
chicken
(Gallus gallus)
Aves -- 36
  • 72 (a)
OneToMany
TCTEX1D2 35
  • 74.14 (n)
  • 76.72 (a)
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 71 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia tctex1d2 35
  • 71.51 (n)
  • 76.07 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5883 35
zebrafish
(Danio rerio)
Actinopterygii Dr.18782 35
tctex1d2 35
  • 64.66 (n)
  • 60.34 (a)
tctex1d2 36
  • 51 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG5359 36
  • 27 (a)
ManyToMany
CG7276 36
  • 27 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea dylt-2 36
  • 35 (a)
OneToMany
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.8237 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 63 (a)
OneToMany
Species with no ortholog for TCTEX1D2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TCTEX1D2 Gene

ENSEMBL:
Gene Tree for TCTEX1D2 (if available)
TreeFam:
Gene Tree for TCTEX1D2 (if available)

Paralogs for TCTEX1D2 Gene

Paralogs for TCTEX1D2 Gene

Selected SIMAP similar genes for TCTEX1D2 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with TCTEX1D2: view

Variants for TCTEX1D2 Gene

Sequence variations from dbSNP and Humsavar for TCTEX1D2 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs769596 -- 196,303,061(-) gcaaa(A/G)tatct intron-variant
rs769597 -- 196,303,104(-) atcca(C/T)ctggg intron-variant
rs769598 -- 196,303,158(-) tcttg(C/T)gctga intron-variant
rs1291755 -- 196,297,105(+) aacct(A/G)ggagg intron-variant
rs1718498 -- 196,314,388(-) cctcc(C/T)gggct intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TCTEX1D2 Gene

Variant ID Type Subtype PubMed ID
dgv1549e1 CNV Complex 17122850
dgv5372n71 CNV Gain 21882294
dgv5373n71 CNV Gain 21882294
nsv878182 CNV Loss 21882294
nsv4183 CNV Loss 18451855
esv2726576 CNV Deletion 23290073

Relevant External Links for TCTEX1D2 Gene

HapMap Linkage Disequilibrium report
TCTEX1D2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TCTEX1D2 Gene

Disorders for TCTEX1D2 Gene

Relevant External Links for TCTEX1D2

Human Genome Epidemiology (HuGE) Navigator
TCTEX1D2
genes like me logo Genes that share disorders with TCTEX1D2: view

No data available for UniProtKB/Swiss-Prot for TCTEX1D2 Gene

Publications for TCTEX1D2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PMID: 20195357) Miyamoto-Sato E. … Yanagawa H. (PLoS ONE 2010) 3
  3. A directed protein interaction network for investigating intracellular signal transduction. (PMID: 21900206) Vinayagam A. … Wanker E.E. (Sci Signal 2011) 3
  4. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PMID: 22990118) Woods N.T. … Monteiro A.N. (Sci Signal 2012) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for TCTEX1D2 Gene

Sources for TCTEX1D2 Gene

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