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Aliases for TCTEX1D1 Gene

Aliases for TCTEX1D1 Gene

  • Tctex1 Domain Containing 1 2 3

External Ids for TCTEX1D1 Gene

Summaries for TCTEX1D1 Gene

GeneCards Summary for TCTEX1D1 Gene

TCTEX1D1 (Tctex1 Domain Containing 1) is a Protein Coding gene. An important paralog of this gene is TCTEX1D2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCTEX1D1 Gene

Genomics for TCTEX1D1 Gene

Genomic Location for TCTEX1D1 Gene

Start:
66,752,457 bp from pter
End:
66,779,047 bp from pter
Size:
26,591 bases
Orientation:
Plus strand

Genomic View for TCTEX1D1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TCTEX1D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCTEX1D1 Gene

Regulatory Elements for TCTEX1D1 Gene

Proteins for TCTEX1D1 Gene

  • Protein details for TCTEX1D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N7M0-TC1D1_HUMAN
    Recommended name:
    Tctex1 domain-containing protein 1
    Protein Accession:
    Q8N7M0
    Secondary Accessions:
    • Q06YR9
    • Q5VYE1

    Protein attributes for TCTEX1D1 Gene

    Size:
    179 amino acids
    Molecular mass:
    20730 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TCTEX1D1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TCTEX1D1 Gene

Proteomics data for TCTEX1D1 Gene at MOPED

Post-translational modifications for TCTEX1D1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TCTEX1D1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TCTEX1D1 Gene

Domains for TCTEX1D1 Gene

Protein Domains for TCTEX1D1 Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

TC1D1_HUMAN
Family:
  • Belongs to the dynein light chain Tctex-type family.:
    • Q8N7M0
genes like me logo Genes that share domains with TCTEX1D1: view

No data available for Gene Families for TCTEX1D1 Gene

Function for TCTEX1D1 Gene

Gene Ontology (GO) - Molecular Function for TCTEX1D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TCTEX1D1: view

Phenotypes for TCTEX1D1 Gene

genes like me logo Genes that share phenotypes with TCTEX1D1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TCTEX1D1 Gene

Localization for TCTEX1D1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TCTEX1D1 Gene COMPARTMENTS Subcellular localization image for TCTEX1D1 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1
mitochondrion 1
peroxisome 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for TCTEX1D1 Gene

Pathways for TCTEX1D1 Gene

SuperPathways for TCTEX1D1 Gene

No Data Available

Interacting Proteins for TCTEX1D1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000282670%0d%0a9606.ENSP00000308312%0d%0a9606.ENSP00000367841%0d%0a9606.ENSP00000356056%0d%0a
Selected Interacting proteins: ENSP00000282670 Q8N7M0-TC1D1_HUMAN for TCTEX1D1 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for TCTEX1D1 Gene

None

No data available for Pathways by source for TCTEX1D1 Gene

Transcripts for TCTEX1D1 Gene

mRNA/cDNA for TCTEX1D1 Gene

Unigene Clusters for TCTEX1D1 Gene

Tctex1 domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TCTEX1D1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b · 7c
SP1: - - - - -
SP2:
SP3: - -
SP4: - - - - - -
SP5:

Relevant External Links for TCTEX1D1 Gene

GeneLoc Exon Structure for
TCTEX1D1
ECgene alternative splicing isoforms for
TCTEX1D1

Expression for TCTEX1D1 Gene

mRNA expression in normal human tissues for TCTEX1D1 Gene

mRNA differential expression in normal tissues according to GTEx for TCTEX1D1 Gene

This gene is overexpressed in Brain - Hypothalamus (5.5) and Brain - Caudate (basal ganglia) (4.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TCTEX1D1 Gene

SOURCE GeneReport for Unigene cluster for TCTEX1D1 Gene Hs.479226

genes like me logo Genes that share expressions with TCTEX1D1: view

Orthologs for TCTEX1D1 Gene

This gene was present in the common ancestor of animals.

Orthologs for TCTEX1D1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TCTEX1D1 36
  • 98.88 (n)
  • 97.21 (a)
TCTEX1D1 37
  • 97 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TCTEX1D1 36
  • 85.85 (n)
  • 82.68 (a)
TCTEX1D1 37
  • 77 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TCTEX1D1 36
  • 87.45 (n)
  • 82.02 (a)
TCTEX1D1 37
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tctex1d1 36
  • 81.53 (n)
  • 76.26 (a)
Tctex1d1 16
Tctex1d1 37
  • 64 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TCTEX1D1 37
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TCTEX1D1 37
  • 64 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tctex1d1 36
  • 80.58 (n)
  • 71.94 (a)
chicken
(Gallus gallus)
Aves TCTEX1D1 37
  • 49 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TCTEX1D1 37
  • 69 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.10706 36
tropical clawed frog
(Silurana tropicalis)
Amphibia tctex1d1 36
  • 71.19 (n)
  • 68.36 (a)
zebrafish
(Danio rerio)
Actinopterygii tctex1d1 36
  • 66.28 (n)
  • 63.58 (a)
tctex1d1 37
  • 64 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG5359 37
  • 23 (a)
ManyToMany
CG7276 37
  • 23 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea dylt-2 37
  • 20 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 47 (a)
OneToOne
Species with no ortholog for TCTEX1D1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TCTEX1D1 Gene

ENSEMBL:
Gene Tree for TCTEX1D1 (if available)
TreeFam:
Gene Tree for TCTEX1D1 (if available)

Paralogs for TCTEX1D1 Gene

Paralogs for TCTEX1D1 Gene

Selected SIMAP similar genes for TCTEX1D1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with TCTEX1D1: view

Variants for TCTEX1D1 Gene

Sequence variations from dbSNP and Humsavar for TCTEX1D1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs471093 -- 66,776,888(+) TGTAT(A/G)GTTTC intron-variant
rs472181 -- 66,760,348(-) ACTAT(C/T)ATATG intron-variant
rs480060 -- 66,756,695(-) GTCAA(A/G)TTACT intron-variant
rs488584 -- 66,754,959(-) TTAAC(A/G/T)TATCA intron-variant, upstream-variant-2KB
rs500905 -- 66,752,321(-) GAGCC(C/G)GGCTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TCTEX1D1 Gene

Variant ID Type Subtype PubMed ID
nsv830093 CNV Gain 17160897
esv1009176 CNV Deletion 20482838

Relevant External Links for TCTEX1D1 Gene

HapMap Linkage Disequilibrium report
TCTEX1D1

Disorders for TCTEX1D1 Gene

No disorders were found for TCTEX1D1 Gene.

No data available for UniProtKB/Swiss-Prot for TCTEX1D1 Gene

Publications for TCTEX1D1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  5. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4

Products for TCTEX1D1 Gene

Sources for TCTEX1D1 Gene

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