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Aliases for TCTE1 Gene

Aliases for TCTE1 Gene

  • T-Complex-Associated-Testis-Expressed 1 2 3
  • Tcte-1 3 4
  • FAP155 3
  • D6S46 3

External Ids for TCTE1 Gene

Previous GeneCards Identifiers for TCTE1 Gene

  • GC06U990121
  • GC06M158967
  • GC06M044357
  • GC06M043969

Summaries for TCTE1 Gene

GeneCards Summary for TCTE1 Gene

TCTE1 (T-Complex-Associated-Testis-Expressed 1) is a Protein Coding gene. An important paralog of this gene is LRRC74A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCTE1 Gene

Genomics for TCTE1 Gene

Regulatory Elements for TCTE1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TCTE1 Gene

Chromosome:
6
Start:
44,278,743 bp from pter
End:
44,297,721 bp from pter
Size:
18,979 bases
Orientation:
Minus strand

Genomic View for TCTE1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for TCTE1 Gene

Proteins for TCTE1 Gene

  • Protein details for TCTE1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5JU00-TCTE1_HUMAN
    Recommended name:
    T-complex-associated testis-expressed protein 1
    Protein Accession:
    Q5JU00
    Secondary Accessions:
    • B4DX59
    • Q8IYS6

    Protein attributes for TCTE1 Gene

    Size:
    501 amino acids
    Molecular mass:
    55632 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TCTE1 Gene

Proteomics data for TCTE1 Gene at MOPED

Post-translational modifications for TCTE1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TCTE1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TCTE1 Gene

Domains & Families for TCTE1 Gene

Gene Families for TCTE1 Gene

Protein Domains for TCTE1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TCTE1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5JU00

UniProtKB/Swiss-Prot:

TCTE1_HUMAN :
  • Contains 5 LRR (leucine-rich) repeats.
Similarity:
  • Contains 5 LRR (leucine-rich) repeats.
genes like me logo Genes that share domains with TCTE1: view

Function for TCTE1 Gene

Molecular function for TCTE1 Gene

GENATLAS Biochemistry:
t-complex associated,testis expressed 1 (formerly D6S46)

Phenotypes for TCTE1 Gene

genes like me logo Genes that share phenotypes with TCTE1: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TCTE1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for TCTE1 Gene

Localization for TCTE1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TCTE1 Gene COMPARTMENTS Subcellular localization image for TCTE1 gene
Compartment Confidence
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TCTE1 Gene

Pathways & Interactions for TCTE1 Gene

SuperPathways for TCTE1 Gene

No Data Available

Interacting Proteins for TCTE1 Gene

Gene Ontology (GO) - Biological Process for TCTE1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TCTE1 Gene

Drugs & Compounds for TCTE1 Gene

No Compound Related Data Available

Transcripts for TCTE1 Gene

mRNA/cDNA for TCTE1 Gene

Unigene Clusters for TCTE1 Gene

T-complex-associated-testis-expressed 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TCTE1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TCTE1 Gene

No ASD Table

Relevant External Links for TCTE1 Gene

GeneLoc Exon Structure for
TCTE1
ECgene alternative splicing isoforms for
TCTE1

Expression for TCTE1 Gene

mRNA expression in normal human tissues for TCTE1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TCTE1 Gene

This gene is overexpressed in Testis (x29.0).

Protein differential expression in normal tissues from HIPED for TCTE1 Gene

This gene is overexpressed in Bone (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TCTE1 Gene



SOURCE GeneReport for Unigene cluster for TCTE1 Gene Hs.189183

genes like me logo Genes that share expression patterns with TCTE1: view

Protein tissue co-expression partners for TCTE1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for TCTE1 Gene

Orthologs for TCTE1 Gene

This gene was present in the common ancestor of animals.

Orthologs for TCTE1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TCTE1 35
  • 80.3 (n)
  • 77.33 (a)
dog
(Canis familiaris)
Mammalia TCTE1 35
  • 87.03 (n)
  • 85.43 (a)
TCTE1 36
  • 83 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tcte1 35
  • 77.46 (n)
  • 77.26 (a)
Tcte1 16
Tcte1 36
  • 78 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TCTE1 35
  • 99.2 (n)
  • 99.2 (a)
TCTE1 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tcte1 35
  • 78.05 (n)
  • 77.98 (a)
oppossum
(Monodelphis domestica)
Mammalia TCTE1 36
  • 64 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TCTE1 36
  • 69 (a)
OneToOne
chicken
(Gallus gallus)
Aves TCTE1 35
  • 66.83 (n)
  • 63.77 (a)
TCTE1 36
  • 61 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TCTE1 36
  • 62 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tcte1 35
  • 63.52 (n)
  • 57.6 (a)
zebrafish
(Danio rerio)
Actinopterygii tcte1 35
  • 60.98 (n)
  • 55.53 (a)
tcte1 36
  • 52 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002751 35
  • 45.54 (n)
  • 28.28 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14325 35
  • 43.6 (n)
  • 31.55 (a)
CG14325 36
  • 28 (a)
OneToMany
Species with no ortholog for TCTE1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TCTE1 Gene

ENSEMBL:
Gene Tree for TCTE1 (if available)
TreeFam:
Gene Tree for TCTE1 (if available)

Paralogs for TCTE1 Gene

Paralogs for TCTE1 Gene

genes like me logo Genes that share paralogs with TCTE1: view

Variants for TCTE1 Gene

Sequence variations from dbSNP and Humsavar for TCTE1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs186555 -- 44,284,461(-) gtgcc(A/G)tcttc intron-variant
rs324138 -- 44,283,101(-) CAAGC(A/G)GCCGG intron-variant
rs324139 -- 44,283,116(-) TGGTT(A/G)TGAAA intron-variant
rs324140 -- 44,284,891(-) actcc(A/G)tctgt intron-variant
rs324141 -- 44,285,591(-) cagat(G/T)tagca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TCTE1 Gene

Variant ID Type Subtype PubMed ID
nsv462936 CNV Loss 19166990
dgv6843n71 CNV Loss 21882294
nsv524398 CNV Loss 19592680
nsv885857 CNV Loss 21882294

Variation tolerance for TCTE1 Gene

Residual Variation Intolerance Score: 78.04% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.38; 85.47% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TCTE1 Gene

HapMap Linkage Disequilibrium report
TCTE1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TCTE1 Gene

Disorders for TCTE1 Gene

Relevant External Links for TCTE1

Genetic Association Database (GAD)
TCTE1
Human Genome Epidemiology (HuGE) Navigator
TCTE1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TCTE1
genes like me logo Genes that share disorders with TCTE1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TCTE1 Gene

Publications for TCTE1 Gene

  1. Cloning, expression, and mapping of TCTEL1, a putative human homologue of murine Tcte1, to 6q. (PMID: 8646886) Watanabe T.K. … Hirai Y. (Cytogenet. Cell Genet. 1996) 2 67
  2. A mouse chromosome 17 gene encodes a testes-specific transcript with unusual properties. (PMID: 2568335) Sarvetnick N. … Silver L.M. (Immunogenetics 1989) 2 67
  3. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67

Products for TCTE1 Gene

Sources for TCTE1 Gene

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