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Aliases for TCTE1 Gene

Aliases for TCTE1 Gene

  • T-Complex-Associated-Testis-Expressed 1 2 3
  • Tcte-1 3 4
  • T-Complex-Associated Testis-Expressed Protein 1 3
  • FAP155 3
  • D6S46 3

External Ids for TCTE1 Gene

Previous GeneCards Identifiers for TCTE1 Gene

  • GC06U990121
  • GC06M158967
  • GC06M044357
  • GC06M043969

Summaries for TCTE1 Gene

GeneCards Summary for TCTE1 Gene

TCTE1 (T-Complex-Associated-Testis-Expressed 1) is a Protein Coding gene. Diseases associated with TCTE1 include meningocele and cleidocranial dysplasia. An important paralog of this gene is LRRC74A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCTE1 Gene

Genomics for TCTE1 Gene

Regulatory Elements for TCTE1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TCTE1 Gene

44,278,743 bp from pter
44,297,721 bp from pter
18,979 bases
Minus strand

Genomic View for TCTE1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TCTE1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCTE1 Gene

Proteins for TCTE1 Gene

  • Protein details for TCTE1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    T-complex-associated testis-expressed protein 1
    Protein Accession:
    Secondary Accessions:
    • B4DX59
    • Q8IYS6

    Protein attributes for TCTE1 Gene

    501 amino acids
    Molecular mass:
    55632 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TCTE1 Gene

Proteomics data for TCTE1 Gene at MOPED

Post-translational modifications for TCTE1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TCTE1 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for TCTE1

No data available for DME Specific Peptides for TCTE1 Gene

Domains for TCTE1 Gene

Gene Families for TCTE1 Gene

Protein Domains for TCTE1 Gene


Suggested Antigen Peptide Sequences for TCTE1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 5 LRR (leucine-rich) repeats.
  • Contains 5 LRR (leucine-rich) repeats.
genes like me logo Genes that share domains with TCTE1: view

Function for TCTE1 Gene

Molecular function for TCTE1 Gene

GENATLAS Biochemistry:
t-complex associated,testis expressed 1 (formerly D6S46)

Phenotypes for TCTE1 Gene

MGI mutant phenotypes for TCTE1:
inferred from 1 alleles
GenomeRNAi human phenotypes for TCTE1:
genes like me logo Genes that share phenotypes with TCTE1: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TCTE1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TCTE1 Gene

Localization for TCTE1 Gene

Subcellular locations from

Jensen Localization Image for TCTE1 Gene COMPARTMENTS Subcellular localization image for TCTE1 gene
Compartment Confidence
cytosol 2
nucleus 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TCTE1 Gene

Pathways for TCTE1 Gene

SuperPathways for TCTE1 Gene

No Data Available

Interacting Proteins for TCTE1 Gene

Gene Ontology (GO) - Biological Process for TCTE1 Gene


No data available for Pathways by source for TCTE1 Gene

Transcripts for TCTE1 Gene

mRNA/cDNA for TCTE1 Gene

Unigene Clusters for TCTE1 Gene

T-complex-associated-testis-expressed 1:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TCTE1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TCTE1 Gene

No ASD Table

Relevant External Links for TCTE1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TCTE1 Gene

mRNA expression in normal human tissues for TCTE1 Gene

mRNA differential expression in normal tissues according to GTEx for TCTE1 Gene

This gene is overexpressed in Testis (29.0).

Protein differential expression in normal tissues for TCTE1 Gene

This gene is overexpressed in Bone (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TCTE1 Gene

SOURCE GeneReport for Unigene cluster for TCTE1 Gene Hs.189183

genes like me logo Genes that share expressions with TCTE1: view

Expression partners for TCTE1 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TCTE1 Gene

Orthologs for TCTE1 Gene

This gene was present in the common ancestor of animals.

Orthologs for TCTE1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TCTE1 35
  • 80.3 (n)
  • 77.33 (a)
(Canis familiaris)
Mammalia TCTE1 35
  • 87.03 (n)
  • 85.43 (a)
TCTE1 36
  • 83 (a)
(Mus musculus)
Mammalia Tcte1 35
  • 77.46 (n)
  • 77.26 (a)
Tcte1 16
Tcte1 36
  • 78 (a)
(Pan troglodytes)
Mammalia TCTE1 35
  • 99.2 (n)
  • 99.2 (a)
TCTE1 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Tcte1 35
  • 78.05 (n)
  • 77.98 (a)
(Monodelphis domestica)
Mammalia TCTE1 36
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia TCTE1 36
  • 69 (a)
(Gallus gallus)
Aves TCTE1 35
  • 66.83 (n)
  • 63.77 (a)
TCTE1 36
  • 61 (a)
(Anolis carolinensis)
Reptilia TCTE1 36
  • 62 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tcte1 35
  • 63.52 (n)
  • 57.6 (a)
(Danio rerio)
Actinopterygii tcte1 35
  • 60.98 (n)
  • 55.53 (a)
tcte1 36
  • 52 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002751 35
  • 45.54 (n)
  • 28.28 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14325 35
  • 43.6 (n)
  • 31.55 (a)
CG14325 36
  • 28 (a)
Species with no ortholog for TCTE1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TCTE1 Gene

Gene Tree for TCTE1 (if available)
Gene Tree for TCTE1 (if available)

Paralogs for TCTE1 Gene

Paralogs for TCTE1 Gene

genes like me logo Genes that share paralogs with TCTE1: view

Variants for TCTE1 Gene

Sequence variations from dbSNP and Humsavar for TCTE1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs186555 -- 44,284,461(-) gtgcc(A/G)tcttc intron-variant
rs324138 -- 44,283,101(-) CAAGC(A/G)GCCGG intron-variant
rs324139 -- 44,283,116(-) TGGTT(A/G)TGAAA intron-variant
rs324140 -- 44,284,891(-) actcc(A/G)tctgt intron-variant
rs324141 -- 44,285,591(-) cagat(G/T)tagca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TCTE1 Gene

Variant ID Type Subtype PubMed ID
nsv462936 CNV Loss 19166990
dgv6843n71 CNV Loss 21882294
nsv524398 CNV Loss 19592680
nsv885857 CNV Loss 21882294

Relevant External Links for TCTE1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TCTE1 Gene

Disorders for TCTE1 Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for TCTE1 Gene in MalaCards »

(2) Diseases for TCTE1 Gene

(2) University of Copenhagen DISEASES for TCTE1 Gene

Relevant External Links for TCTE1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with TCTE1: view

No data available for OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for TCTE1 Gene

Publications for TCTE1 Gene

  1. A mouse chromosome 17 gene encodes a testes-specific transcript with unusual properties. (PMID: 2568335) Sarvetnick N. … Silver L.M. (Immunogenetics 1989) 2 3
  2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3 48
  3. Sequence divergence within the sperm-specific polypeptide TCTE1 is correlated with species-specific differences in sperm binding to zona-intact eggs. (PMID: 9570741) Juneja R. … Silver L.M. (J. Androl. 1998) 3
  4. Linkage mapping and fluorescence in situ hybridization of TCTE1 on human chromosome 6p: analysis of dinucleotide polymorphisms on native gels. (PMID: 1916824) Kwiatkowski T.J. … Zoghbi H.Y. (Genomics 1991) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TCTE1 Gene

Sources for TCTE1 Gene

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