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Aliases for TCP11L2 Gene

Aliases for TCP11L2 Gene

  • T-Complex 11, Testis-Specific-Like 2 2 3
  • T-Complex 11 (Mouse) Like 2 2
  • T-Complex 11 (Mouse)-Like 2 2

External Ids for TCP11L2 Gene

Summaries for TCP11L2 Gene

GeneCards Summary for TCP11L2 Gene

TCP11L2 (T-Complex 11, Testis-Specific-Like 2) is a Protein Coding gene. An important paralog of this gene is TCP11X2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCP11L2 Gene

Genomics for TCP11L2 Gene

Genomic Location for TCP11L2 Gene

Start:
106,301,929 bp from pter
End:
106,347,587 bp from pter
Size:
45,659 bases
Orientation:
Plus strand

Genomic View for TCP11L2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TCP11L2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCP11L2 Gene

Regulatory Elements for TCP11L2 Gene

Proteins for TCP11L2 Gene

  • Protein details for TCP11L2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N4U5-T11L2_HUMAN
    Recommended name:
    T-complex protein 11-like protein 2
    Protein Accession:
    Q8N4U5
    Secondary Accessions:
    • B2RA65
    • G3V1Y9

    Protein attributes for TCP11L2 Gene

    Size:
    519 amino acids
    Molecular mass:
    58091 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TCP11L2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TCP11L2 Gene

Proteomics data for TCP11L2 Gene at MOPED

Post-translational modifications for TCP11L2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TCP11L2 Gene

Domains for TCP11L2 Gene

Protein Domains for TCP11L2 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

T11L2_HUMAN
Family:
  • Belongs to the TCP11 family.:
    • Q8N4U5
genes like me logo Genes that share domains with TCP11L2: view

No data available for Gene Families for TCP11L2 Gene

Function for TCP11L2 Gene

Phenotypes for TCP11L2 Gene

genes like me logo Genes that share phenotypes with TCP11L2: view

miRNA for TCP11L2 Gene

miRTarBase miRNAs that target TCP11L2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for TCP11L2 Gene

Localization for TCP11L2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TCP11L2 Gene COMPARTMENTS Subcellular localization image for TCP11L2 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for TCP11L2 Gene

Pathways for TCP11L2 Gene

SuperPathways for TCP11L2 Gene

No Data Available

Interacting Proteins for TCP11L2 Gene

Gene Ontology (GO) - Biological Process for TCP11L2 Gene

None

No data available for Pathways by source for TCP11L2 Gene

Transcripts for TCP11L2 Gene

Unigene Clusters for TCP11L2 Gene

T-complex 11, testis-specific-like 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TCP11L2 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15
SP1: - - - - - - - -
SP2: - - - - - -
SP3: - - - - -
SP4: -
SP5: - - - - -
SP6: - - - - -
SP7:
SP8: - -

Relevant External Links for TCP11L2 Gene

GeneLoc Exon Structure for
TCP11L2
ECgene alternative splicing isoforms for
TCP11L2

Expression for TCP11L2 Gene

mRNA expression in normal human tissues for TCP11L2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TCP11L2 Gene

This gene is overexpressed in Whole Blood (5.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TCP11L2 Gene

SOURCE GeneReport for Unigene cluster for TCP11L2 Gene Hs.696047

genes like me logo Genes that share expressions with TCP11L2: view

Orthologs for TCP11L2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TCP11L2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TCP11L2 36
  • 99.36 (n)
  • 99.04 (a)
TCP11L2 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TCP11L2 36
  • 89.66 (n)
  • 90.94 (a)
TCP11L2 37
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TCP11L2 36
  • 92.3 (n)
  • 92.82 (a)
TCP11L2 37
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tcp11l2 36
  • 83.43 (n)
  • 79.11 (a)
Tcp11l2 16
Tcp11l2 37
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TCP11L2 37
  • 80 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TCP11L2 37
  • 82 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tcp11l2 36
  • 83.17 (n)
  • 79.5 (a)
chicken
(Gallus gallus)
Aves TCP11L2 36
  • 72.83 (n)
  • 72.83 (a)
TCP11L2 37
  • 71 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TCP11L2 37
  • 70 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.20084 36
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.3807 36
tcp11l2 36
  • 63.87 (n)
  • 59.68 (a)
zebrafish
(Danio rerio)
Actinopterygii tcp11l2 36
  • 59.12 (n)
  • 53.19 (a)
tcp11l2 37
  • 52 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG16721 37
  • 31 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea M05D6.2 37
  • 23 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SOK1 37
  • 12 (a)
OneToMany
SOK1 39
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 20 (a)
OneToMany
Species with no ortholog for TCP11L2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TCP11L2 Gene

ENSEMBL:
Gene Tree for TCP11L2 (if available)
TreeFam:
Gene Tree for TCP11L2 (if available)

Paralogs for TCP11L2 Gene

Paralogs for TCP11L2 Gene

Selected SIMAP similar genes for TCP11L2 Gene using alignment to 9 proteins:

genes like me logo Genes that share paralogs with TCP11L2: view

Variants for TCP11L2 Gene

Sequence variations from dbSNP and Humsavar for TCP11L2 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type MAF
rs904614 -- 106,304,556(+) TCTGC(A/C)ATTTT intron-variant
rs1134577 -- 106,331,060(-) TTAAA(A/G)ACAAT intron-variant
rs1532586 -- 106,306,806(+) atggc(A/G)agttc intron-variant
rs1532587 -- 106,306,931(+) TTGCA(A/G)TTCTG intron-variant
rs1921952 -- 106,330,916(-) TACTA(C/T)AATAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TCP11L2 Gene

Variant ID Type Subtype PubMed ID
esv2746335 CNV Deletion 23290073
esv2746336 CNV Deletion 23290073

Relevant External Links for TCP11L2 Gene

HapMap Linkage Disequilibrium report
TCP11L2
Human Gene Mutation Database (HGMD)
TCP11L2

Disorders for TCP11L2 Gene

No disorders were found for TCP11L2 Gene.

No data available for UniProtKB/Swiss-Prot for TCP11L2 Gene

Publications for TCP11L2 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  2. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  3. Genome-wide association study of Tourette's syndrome. (PMID: 22889924) Scharf J.M. … Pauls D.L. (Mol. Psychiatry 2013) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for TCP11L2 Gene

Sources for TCP11L2 Gene

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