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TCP11L1 Gene

protein-coding   GIFtS: 50
GCID: GC11P033018

T-Complex 11, Testis-Specific-Like 1

(Previous name: t-complex 11 (mouse) like 1)
  Search for TCP11L1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
T-Complex 11, Testis-Specific-Like 11 2
T-Complex 11 (Mouse) Like 11
dJ85M6.32
T-Complex 11-Like 12
T-Complex Protein 11-Like Protein 12

External Ids:    HGNC: 256551   Entrez Gene: 553462   Ensembl: ENSG000001761487   UniProtKB: Q9NUJ33   

Export aliases for TCP11L1 gene to outside databases

Previous GC identifer: GC11P032755


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TCP11L1 Gene:
TCP11L1 (t-complex 11, testis-specific-like 1) is a protein-coding gene. An important paralog of this gene is TCP11X1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NT_009237.19  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TCP11L1 gene promoter:
         LHX3b/Lhx3b   POU2F1   Pax-5   LHX3a/Lhx3a   Evi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTCP11L1 promoter sequence
   Search Chromatin IP Primers for TCP11L1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TCP11L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p13   Ensembl cytogenetic band:  11p13   HGNC cytogenetic band: 11p13

TCP11L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCP11L1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P033018:  view genomic region     (about GC identifiers)

Start:
33,060,963 bp from pter      End:
33,127,489 bp from pter
Size:
66,527 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: T11L1_HUMAN, Q9NUJ3 (See protein sequence)
Recommended Name: T-complex protein 11-like protein 1  
Size: 509 amino acids; 57035 Da
Secondary accessions: D3DR01 Q8IVX4

Explore the universe of human proteins at neXtProt for TCP11L1: NX_Q9NUJ3

Explore proteomics data for TCP11L1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TCP11L1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001139013.1  NP_060863.3  

    ENSEMBL proteins: 
     ENSP00000436428   ENSP00000335595   ENSP00000435667   ENSP00000431200   ENSP00000473628  
     ENSP00000435870   ENSP00000433067   ENSP00000436471   ENSP00000395070   ENSP00000316279  

    TCP11L1 Human Recombinant Protein Products:

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    Novus Biologicals TCP11L1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TCP11L1

     
    Search eBioscience for Proteins for TCP11L1 

    TCP11L1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Abcam antibodies for TCP11L1
    Cloud-Clone Corp. Antibodies for TCP11L1
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    LSBio Antibodies in human, mouse, rat for TCP11L1

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    Cloud-Clone Corp. ELISAs for TCP11L1
    Cloud-Clone Corp. CLIAs for TCP11L1
    Search eBioscience for ELISAs for TCP11L1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR008862 Tcp11

    Graphical View of Domain Structure for InterPro Entry Q9NUJ3

    ProtoNet protein and cluster: Q9NUJ3

    UniProtKB/Swiss-Prot: T11L1_HUMAN, Q9NUJ3
    Similarity: Belongs to the TCP11 family


    Find genes that share domains with TCP11L1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 GenomeRNAi human phenotype for TCP11L1:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TCP11L1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TCP11L1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TCP11L1

    miRNA
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    miRTarBase miRNAs that target TCP11L1:
    hsa-mir-92b-3p (MIRT040728)

    Block miRNA regulation of human, mouse, rat TCP11L1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TCP11L1 (see all 19):
    hsa-miR-30c hsa-miR-623 hsa-miR-429 hsa-miR-30d hsa-miR-373* hsa-miR-421 hsa-miR-30a hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmidTCP11L1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TCP11L1
    Predesigned siRNA for gene silencing in human, mouse, rat TCP11L1

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for TCP11L1
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    GenScript: all cDNA clones in your preferred vector (see all 2): TCP11L1 (NM_001145541)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TCP11L1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCP11L1

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TCP11L1 
    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCP11L1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol2
    nucleus2
    extracellular1
    golgi apparatus1
    mitochondrion1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005874microtubule IDA--

    Find genes that share ontologies with TCP11L1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TCP11L1
    Interactions:

        Search GeneGlobe Interaction Network for TCP11L1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for TCP11L1 (Q9NUJ33 ENSP000003355954) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IKBKGQ9Y6K93, ENSP000003586224I2D: score=1 STRING: ENSP00000358622
    RASSF8Q8NHQ83I2D: score=5 
    PIH1D1Q9NWS03I2D: score=3 
    TUBB2BQ9BVA13I2D: score=3 
    PIK3C3Q8NEB93I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TCP11L1 (T11L1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TCP11L1 gene (2 alternative transcripts): 
    NM_001145541.1  NM_018393.3  

    Unigene Cluster for TCP11L1:

    T-complex 11, testis-specific-like 1
    Hs.655341  [show with all ESTs]
    Unigene Representative Sequence: BC030582
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000532687 ENST00000530419 ENST00000334274(uc001mud.3) ENST00000527661(uc001muf.1)
    ENST00000530171 ENST00000528107(uc009yju.3) ENST00000602733 ENST00000528898
    ENST00000531632 ENST00000528962 ENST00000432887(uc010rei.2 uc001mue.3)
    ENST00000324357
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TCP11L1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TCP11L1 (see all 19):
    hsa-miR-30c hsa-miR-623 hsa-miR-429 hsa-miR-30d hsa-miR-373* hsa-miR-421 hsa-miR-30a hsa-miR-4325
    SwitchGear 3'UTR luciferase reporter plasmidTCP11L1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TCP11L1
    Predesigned siRNA for gene silencing in human, mouse, rat TCP11L1
    Clone
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    OriGene clones in human, mouse for TCP11L1 (see all 11)
    OriGene ORF clones in mouse, rat for TCP11L1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TCP11L1 (NM_001145541)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TCP11L1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCP11L1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TCP11L1
    OriGene qSTAR qPCR primer pairs in human, mouse for TCP11L1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TCP11L1
      QuantiTect SYBR Green Assays in human, mouse, rat TCP11L1
      QuantiFast Probe-based Assays in human, mouse, rat TCP11L1

    Additional mRNA sequence: 

    AK002198.1 AK090646.1 BC030582.1 BC041696.1 

    9 DOTS entries:

    DT.406380  DT.100723760  DT.120739102  DT.91834780  DT.438827  DT.95305594  DT.97838525  DT.95075559 
    DT.95079212 

    Selected AceView cDNA sequences (see all 52):

    R81557 BC041696 BX105318 AI074804 BM462324 AI803015 NM_018393 BM693709 
    AK090646 BM670852 AI627556 AU117035 BM451702 CB989865 BX282710 AK002198 
    BC030582 BQ716694 T27081 BM564758 AA182444 T39898 BX456983 AK021448 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TCP11L1 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b
    SP1:              -     -     -           -                                                                     
    SP2:                          -           -                                                                     
    SP3:                          -           -                                                                     
    SP4:              -     -     -           -     -     -     -                                                   
    SP5:              -     -     -                                                                                 


    ECgene alternative splicing isoforms for TCP11L1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TCP11L1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCTCACCTC
    TCP11L1 Expression
    About this image

    TCP11L1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TCP11L1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.655341
        Custom PCR Arrays for TCP11L1
    Primer
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    OriGene qPCR primer pairs and template standards for TCP11L1
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    QuantiFast Probe-based Assays in human, mouse, rat TCP11L1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCP11L1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TCP11L1 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tcp11l11 , 5 t-complex 11 like 11, 5 85.33(n)1
    85.27(a)1
      2 (54.87 cM)5
    3205541  NM_177190.51  NP_796164.11 
     1046572885 
    chicken
    (Gallus gallus)
    Aves TCP11L11 t-complex 11 (mouse)-like 1 69.11(n)
    71.14(a)
      421594  NM_001199407.1  NP_001186336.1 
    lizard
    (Anolis carolinensis)
    Reptilia TCP11L16
    t-complex 11, testis-specific-like 1
    66(a)
    1 ↔ 1
    1(61485911-61510255)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tcp11l11 t-complex 11, testis-specific-like 1 63.29(n)
    61.26(a)
      100127643  NM_001112989.1  NP_001106460.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tcp11l11 t-complex 11 (mouse)-like 1 58.88(n)
    55.89(a)
      541488  NM_001014301.2  NP_001014323.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG167211 CG16721 45.55(n)
    34.99(a)
      31520  NM_132047.2  NP_572275.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_M05D6.21 CELE_M05D6.2 44.09(n)
    32.49(a)
      174353  NM_063386.4  NP_495787.2 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SOK16
    Protein whose overexpression suppresses the growth...
    12(a)
    1 → many
    IV(458542-461247) YDR006C


    ENSEMBL Gene Tree for TCP11L1 (if available)
    TreeFam Gene Tree for TCP11L1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TCP11L1 gene
    TCP11X12  TCP11L22  TCP11X22  TCP112  
    6 SIMAP similar genes for TCP11L1 using alignment to 8 protein entries:     T11L1_HUMAN (see all proteins):
    ECD    TCP11X1    TCP11    TCP11L2    TCP11X2    RPS6KA5

    Find genes that share paralogs with TCP11L1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TCP11L1 (see all 846)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1127238511,2
    C,Funtested133076240(+) ACTTTA/C/TAGATT 4 Q * stg12CSA NA 4550
    rs114222181,2
    C--32999968(+) GTCTC-/A/AA  
            
    AAAAA
    2 -- int1 trp30--------
    rs15700471,2
    C,F,H--33058984(-) CTGCAA/GGGACT 1 -- us2k115Minor allele frequency- G:0.40EA NA WA 1986
    rs1466501481,2
    C--33059034(+) AATATC/TGAAAC 1 -- us2k10--------
    rs37587481,2
    C--33059040(-) TGTACG/TGTTTC 1 -- us2k1 tfbs30--------
    rs37587471,2
    C,F,A,H--33059057(-) GTAATC/TTTTTA 1 -- us2k1 tfbs39Minor allele frequency- T:0.45NA WA EA 374
    rs110321101,2
    C,F--33059118(+) CTCTCC/AAGGTG 1 -- us2k15Minor allele frequency- A:0.18NA WA EA 362
    rs44456051,2
    C,F,A,H--33059124(+) AGGTGA/GAACTT 1 -- us2k112Minor allele frequency- G:0.13NA WA CSA EA 378
    rs30786281,2
    C--33059196(+) ttttt-/TTTTTTT
    /TTTTTTTT
    gagat
    1 -- us2k11NA 2
    rs1128097891,2
    C--33059203(+) AGATGC/TAGTCT 1 -- us2k11Minor allele frequency- T:0.50CSA 2

    HapMap Linkage Disequilibrium report for TCP11L1 (33060963 - 33127489 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TCP11L1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2658399CNV Deletion23128226
    nsv521130CNV Gain19592680
    dgv1065n71CNV Gain21882294
    nsv467786CNV Gain19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TCP11L1
    DNA2.0 Custom Variant and Variant Library Synthesis for TCP11L1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with TCP11L1           About GenesLikeMe

    Genetic Association Database (GAD): TCP11L1
    Human Genome Epidemiology (HuGE) Navigator: TCP11L1 (1 document)

    Export disorders for TCP11L1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TCP11L1 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with TCP11L1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Host determinants of HIV-1 control in African Americans. (PubMed id 20205591)1, 4 Pelak K.... . (J. Infect. Dis. 2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)
    8. Expanding the substantial interactome of NEMO using protein microarrays. (PubMed id 20098747)1 Fenner B.J....Prehn J.H. (PLoS ONE 2010)
    9. Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PubMed id 19953087)1 Persaud A....Rotin D. (Mol. Syst. Biol. 2009)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55346 HGNC: 25655 AceView: FLJ11336 Ensembl:ENSG00000176148 euGenes: HUgn55346
    ECgene: TCP11L1 H-InvDB: TCP11L1

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for TCP11L1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for TCP11L1 gene:
    Search GeneIP for patents involving TCP11L1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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