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TCP11 Gene

protein-coding   GIFtS: 52
GCID: GC06M035735

T-Complex 11, Testis-Specific

(Previous names: t-complex 11 (a murine tcp homolog), t-complex 11 homolog...)
(Previous symbol: D6S230E)
  Search for TCP11
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
T-Complex 11, Testis-Specific1 2     T-Complex 11 Homolog (Mouse)1
D6S230E1 2 5     FPPR2
T-Complex 11 (A Murine Tcp Homolog)1 2     T-Complex 11 Homolog2
Fertilization-Promoting Peptide Receptor1 2     T-Complex Protein 11 Homolog2

External Ids:    HGNC: 116581   Entrez Gene: 69542   Ensembl: ENSG000001246787   OMIM: 1869825   UniProtKB: Q8WWU53   

Export aliases for TCP11 gene to outside databases

Previous GC identifers: GC06M035087 GC06M035132 GC06M035193 GC06M034807 GC06M035133 GC06M035240


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TCP11 Gene:
TCP11 (t-complex 11, testis-specific) is a protein-coding gene. An important paralog of this gene is TCP11X1.

UniProtKB/Swiss-Prot: TCP11_HUMAN, Q8WWU5
Function: May play an important role in sperm function and fertility

Gene Wiki entry for TCP11 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_007592.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TCP11 gene promoter:
         HOXA9   HOXA9B   MIF-1   Meis-1b   MEF-2A   FOXI1   POU2F1   POU2F1a   aMEF-2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTCP11 promoter sequence
   Search Chromatin IP Primers for TCP11

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TCP11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.31   Ensembl cytogenetic band:  6p21.31   HGNC cytogenetic band: 6p21.31

TCP11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCP11 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M035735:  view genomic region     (about GC identifiers)

Start:
35,085,848 bp from pter      End:
35,116,387 bp from pter
Size:
30,540 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TCP11_HUMAN, Q8WWU5 (See protein sequence)
Recommended Name: T-complex protein 11 homolog  
Size: 503 amino acids; 56141 Da
Secondary accessions: B2RCE9 B3KQ27 B7Z7B5 B7Z7G1 B7Z7H4 B7Z7S8 E7EP29 J3KNG1 Q8NF85 Q9NQZ9
Q9NR39
Alternative splicing: 7 isoforms:  Q8WWU5-1   Q8WWU5-2   Q8WWU5-3   Q8WWU5-4   Q8WWU5-5   Q8WWU5-6   Q8WWU5-7   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for TCP11: NX_Q8WWU5

Explore proteomics data for TCP11 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TCP11 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (7 alternative transcripts): 
    NP_001087197.1  NP_001248746.1  NP_001248747.1  NP_001248748.1  NP_001248749.1  NP_001248750.1  NP_061149.1  

    ENSEMBL proteins: 
     ENSP00000402816   ENSP00000363091   ENSP00000422105   ENSP00000421916   ENSP00000423293  
     ENSP00000399012   ENSP00000308708   ENSP00000404479   ENSP00000363085   ENSP00000425995  
     ENSP00000415320   ENSP00000415562   ENSP00000421103   ENSP00000422259   ENSP00000422774  
     ENSP00000423183   ENSP00000425849   ENSP00000421333   ENSP00000421386   ENSP00000424209  
     ENSP00000422940   ENSP00000421349   ENSP00000424332   ENSP00000244645  

    TCP11 Human Recombinant Protein Products:

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    Novus Biologicals TCP11 Proteins
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    Cloud-Clone Corp. Proteins for TCP11

     
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    TCP11 Assay Products:

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    Cloud-Clone Corp. ELISAs for TCP11
    Cloud-Clone Corp. CLIAs for TCP11
    Search eBioscience for ELISAs for TCP11 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR008862 Tcp11

    Graphical View of Domain Structure for InterPro Entry Q8WWU5

    ProtoNet protein and cluster: Q8WWU5

    UniProtKB/Swiss-Prot: TCP11_HUMAN, Q8WWU5
    Similarity: Belongs to the TCP11 family


    Find genes that share domains with TCP11           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TCP11_HUMAN, Q8WWU5
    Function: May play an important role in sperm function and fertility

         Genatlas biochemistry entry for TCP11:
    T-complex 11 (murine tcp homolog)

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TCP11
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TCP11

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TCP11
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TCP11

    miRNA
    Products:
        
    miRTarBase miRNAs that target TCP11:
    hsa-mir-122-5p (MIRT023346)

    Block miRNA regulation of human, mouse, rat TCP11 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TCP11
    SwitchGear 3'UTR luciferase reporter plasmidTCP11 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TCP11
    Predesigned siRNA for gene silencing in human, mouse, rat TCP11

    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for TCP11
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    GenScript: all cDNA clones in your preferred vector (see all 2): TCP11 (NM_001093728)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TCP11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCP11

    Cell Line
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCP11


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TCP11_HUMAN, Q8WWU5: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    extracellular1
    mitochondrion1
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TCP11           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TCP11
    Interactions:

        Search GeneGlobe Interaction Network for TCP11

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for TCP11 (Q8WWU53 ENSP000003087084) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    VAV2P527353, ENSP000003609164I2D: score=1 STRING: ENSP00000360916
    IKBKGQ9Y6K93, ENSP000003586224I2D: score=1 STRING: ENSP00000358622
    DNAJC2ENSP000003685654STRING: ENSP00000368565
    HFM1ENSP000003594544STRING: ENSP00000359454
    JADE1ENSP000002263194STRING: ENSP00000226319
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007275multicellular organismal development TAS1893875
    GO:0007283spermatogenesis IEA--
    GO:0030154cell differentiation IEA--

    Find genes that share ontologies with TCP11           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TCP11

    1 Novoseek inferred chemical compound relationship for TCP11 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adenylate 54.7 2 9322250 (1)



    Find genes that share compounds with TCP11           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TCP11 gene (7 alternative transcripts): 
    NM_001093728.2  NM_001261817.1  NM_001261818.1  NM_001261819.1  NM_001261820.1  NM_001261821.1  NM_018679.5  

    Unigene Cluster for TCP11:

    T-complex 11, testis-specific
    Hs.435371  [show with all ESTs]
    Unigene Representative Sequence: NM_001261820
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27):
    ENST00000412155 ENST00000373979(uc003ojz.1) ENST00000502480 ENST00000504758
    ENST00000505911 ENST00000455706 ENST00000311875(uc003okd.2 uc011dsu.1 uc011dsv.1 uc011dsw.1)
    ENST00000444780 ENST00000373974 ENST00000512012 ENST00000418521 ENST00000427376
    ENST00000486638 ENST00000469514 ENST00000492680 ENST00000507706 ENST00000479418
    ENST00000505400
    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidTCP11 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TCP11
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    OriGene ORF clones in mouse, rat for TCP11
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    GenScript: all cDNA clones in your preferred vector (see all 2): TCP11 (NM_001093728)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCP11
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TCP11
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TCP11
      QuantiTect SYBR Green Assays in human, mouse, rat TCP11
      QuantiFast Probe-based Assays in human, mouse, rat TCP11

    Additional mRNA sequence: 

    AF260330.1 AF269223.1 AF536532.1 AF536533.1 AK057234.1 AK098590.1 AK301778.1 AK301975.1 
    AK302022.1 AK302375.1 AK302456.1 AK315078.1 AK316403.1 AY069943.1 BC033729.1 BC040003.1 
    BC048418.1 BC090050.1 

    16 DOTS entries:

    DT.40256097  DT.91725898  DT.91749044  DT.91725896  DT.121388878  DT.97778236  DT.100786149  DT.121388945 
    DT.95363801  DT.121388922  DT.95363798  DT.121388915  DT.91661294  DT.100786147  DT.121388976  DT.91725895 

    Selected AceView cDNA sequences (see all 116):

    BI829801 AF536533 BI561278 BX280473 CD557279 BI829842 BC040003 BG700615 
    BG716925 AF260330 AF536532 AK057234 BI829267 AF269223 BI828236 BG721134 
    BC033729 AY069943 BC048418 BG722302 BP371219 NM_018679 BI831565 BI560880 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TCP11 (see all 18)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7 ^ 8a · 8b · 8c · 8d · 8e ^ 9a · 9b · 9c · 9d ^ 10 ^
    SP1:                                            -                                               -                                                               
    SP2:                                            -                 -                             -                                                               
    SP3:                                            -                 -     -     -                 -                                                               
    SP4:                                            -     -     -                                   -                                                               
    SP5:                                -     -     -     -     -                 -     -     -     -     -                                                         

    ExUns: 11a · 11b · 11c ^ 12 ^ 13
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for TCP11

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TCP11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAACACCAA
    TCP11 Expression
    About this image


    TCP11 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Mature Sertoli Cells Seminiferous Tubules
             Testis Interstitium
     
     Pancreas (Endocrine System)
             Islets of Langerhans
    TCP11 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TCP11 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.435371

    UniProtKB/Swiss-Prot: TCP11_HUMAN, Q8WWU5
    Tissue specificity: Expressed only in fertile adult testis

        Custom PCR Arrays for TCP11
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCP11

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TCP11 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tcp111 , 5 t-complex protein 111, 5 77.78(n)1
    77.03(a)1
      17 (14.62 cM)5
    214631  NM_013687.31  NP_038715.21 
     280667475 
    chicken
    (Gallus gallus)
    Aves TCP111 t-complex 11 homolog (mouse) 59.71(n)
    48.64(a)
      419897  XM_418022.4  XP_418022.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    47(a)
    1 → many
    4(120831421-120853376)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG167216
    --
    26(a)
    1 → many
    X(5773891-5777433)
    worm
    (Caenorhabditis elegans)
    Secernentea M05D6.26
    Protein M05D6.2 (M05D6.2) mRNA, complete cds
    23(a)
    1 → many
    II(8468109-8470160) WBGene00010875
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SOK16
    Protein whose overexpression suppresses the growth...
    12(a)
    1 → many
    IV(458542-461247) YDR006C


    ENSEMBL Gene Tree for TCP11 (if available)
    TreeFam Gene Tree for TCP11 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TCP11 gene
    TCP11X12  TCP11L12  TCP11L22  TCP11X22  
    4 SIMAP similar genes for TCP11 using alignment to 13 protein entries:     TCP11_HUMAN (see all proteins):
    TCP11X2    TCP11X1    TCP11L1    TCP11L2

    Find genes that share paralogs with TCP11           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TCP11 (see all 518)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs349483241,2
    C--34813541(+) CTTTC-/TTTTTT 5 -- int10--------
    rs1885395061,2
    --35085506(+) CTTGTC/TGCATT 7 -- int10--------
    rs1491303761,2
    --35085567(+) AACCAC/TGTCCT 7 -- int10--------
    rs412700481,2
    F--35085821(+) GGCCTC/TAGCTG 7 -- int11Minor allele frequency- T:0.01NA 120
    rs1812020261,2
    --35085874(+) ATTAAC/TGAATG 7 -- ut310--------
    rs1862020231,2
    --35085932(+) GTACTA/GGCTGC 7 -- ut310--------
    rs42564201,2
    H--35085958(+) AGCTCA/TCTGTC 7 -- ut314Minor allele frequency- T:0.00NS EA 416
    rs788237601,2
    C--35086010(+) TCCTCT/CTGGGT 7 -- ut312Minor allele frequency- C:0.14CSA WA 120
    rs1126055931,2
    C,F--35086073(+) TCCAGT/GGCCTG 14 /A syn13Minor allele frequency- G:0.01CSA NA EU 5873
    rs22340511,2,,4
    C,F,H--35086272(-) TCAGCG/AGATCC 14 /Q /R mis1 ese38Minor allele frequency- A:0.01NS EA NA EU 6379

    HapMap Linkage Disequilibrium report for TCP11 (35085848 - 35116387 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for TCP11:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1001098CNV Deletion20482838
    esv2633690CNV Deletion19546169
    esv1533887CNV Deletion17803354
    nsv349272CNV Loss16902084
    nsv511879CNV Loss21212237

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TCP11
    DNA2.0 Custom Variant and Variant Library Synthesis for TCP11

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 186982    OMIM disorders: --


    Find genes that share disorders with TCP11           About GenesLikeMe

    Genetic Association Database (GAD): TCP11
    Human Genome Epidemiology (HuGE) Navigator: TCP11 (1 document)

    Export disorders for TCP11 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TCP11 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with TCP11)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular characterization of the TCP11 gene which is the human homologue of the mouse gene encoding the receptor of fertilization promoting peptide. (PubMed id 11756566)1, 2, 3 Ma Y.... Milunsky A. (Mol. Hum. Reprod. 2002)
    2. A testis-expressed Zn finger gene (ZNF76) in human 6p21.3 centromeric to the MHC is closely linked to the human homolog of the T-complex gene tcp-11. (PubMed id 1427894)1, 3, 9 Ragoussis J.... Trowsdale J. (Genomics 1992)
    3. Human t-complex protein 11 (TCP11), a testis-specific gene product, is a potential determinant of the sperm morphology. (PubMed id 21597245)1, 3 Liu Y....Ma Y. (Tohoku J. Exp. Med. 2011)
    4. The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. (PubMed id 20546612)1, 4 Zhao J....Grant S.F. (BMC Med. Genet. 2010)
    5. Many sequence variants affecting diversity of adult human height. (PubMed id 18391951)1, 4 Gudbjartsson D.F....Stefansson K. (Nat. Genet. 2008)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    7. Cloning, expression and alternative splicing of a novel isoform of human TCP11b gene. (PubMed id 12545228)1, 2 Ma Y.X.... Sun Y. (Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 2003)
    8. Cloning, expression, and alternative splicing of the novel isoform of hTCP11 gene. (PubMed id 12905703)1, 2 Ma Y.X.... Xu W.M. (Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2003)
    9. TCP-11, the product of a mouse t-complex gene, plays a role in stimulation of capacitation and inhibition of the spontaneous acrosome reaction. (PubMed id 9322250)1, 9 Fraser L.R....Dudley R.K. (Mol. Reprod. Dev. 1997)
    10. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6954 HGNC: 11658 AceView: TCP11 Ensembl:ENSG00000124678 euGenes: HUgn6954
    ECgene: TCP11 H-InvDB: TCP11

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TCP11 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TCP11 gene:
    Search GeneIP for patents involving TCP11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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