Aliases for TCN2 Gene
External Ids for TCN2 Gene
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
GeneCards Summary for TCN2 Gene
TCN2 (Transcobalamin II) is a Protein Coding gene. Diseases associated with TCN2 include fasciolopsiasis and transcobalamin ii deficiency. Among its related pathways are Disease and Metabolism. GO annotations related to this gene include cobalamin binding. An important paralog of this gene is TCN1.
UniProtKB/Swiss-Prot for TCN2 Gene
Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells