Aliases for TCN1 Gene
External Ids for TCN1 Gene
Previous GeneCards Identifiers for TCN1 Gene
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells. [provided by RefSeq, Jul 2008]
GeneCards Summary for TCN1 Gene
TCN1 (Transcobalamin 1) is a Protein Coding gene. Diseases associated with TCN1 include Transcobalamin I Deficiency and Transcobalamin Ii Deficiency. Among its related pathways are Metabolism and Metabolism of water-soluble vitamins and cofactors. GO annotations related to this gene include cobalamin binding. An important paralog of this gene is GIF.
UniProtKB/Swiss-Prot for TCN1 Gene
Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.