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TCN1 Gene

protein-coding   GIFtS: 61
GCID: GC11M059620

Transcobalamin I (Vitamin B12 Binding Protein, R Binder...

  See TCN1-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transcobalamin I (Vitamin B12 Binding Protein, R Binder Family)1 2     TCI2 3
TC12 3 5     transcobalamin-12
haptocorin1 2     TC I3
haptocorrin1 2     Transcobalamin I3
TC-12 3     

External Ids:    HGNC: 116521   Entrez Gene: 69472   Ensembl: ENSG000001348277   OMIM: 1899055   UniProtKB: P200613   

Export aliases for TCN1 gene to outside databases

Previous GC identifers: GC11M062014 GC11M061133 GC11M059871 GC11M059395 GC11M059376 GC11M055967


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TCN1 Gene:
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively
referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of
secondary granules in neutrophils and facilitates the transport of cobalamin into cells. (provided by RefSeq, Jul
2008)

GeneCards Summary for TCN1 Gene:
TCN1 (transcobalamin I (vitamin B12 binding protein, R binder family)) is a protein-coding gene. Diseases associated with TCN1 include vitamin b12 deficiency, and pernicious anemia. GO annotations related to this gene include cobalamin binding. An important paralog of this gene is GIF.

UniProtKB/Swiss-Prot: TCO1_HUMAN, P20061
Function: Vitamin B12-binding protein. Transports cobalamin into cells

Gene Wiki entry for TCN1 (Haptocorrin) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000011.9  NC_018922.2  NT_167190.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TCN1 gene promoter:
         Brachyury   FOXD3   CUTL1   NF-kappaB   NF-kappaB1   POU3F2   TGIF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTCN1 promoter sequence
   Search Chromatin IP Primers for TCN1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TCN1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q11-q12   Ensembl cytogenetic band:  11q12.1   HGNC cytogenetic band: 11q11-q12

TCN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCN1 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M059620:  view genomic region     (about GC identifiers)

Start:
59,620,273 bp from pter      End:
59,634,048 bp from pter
Size:
13,776 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TCO1_HUMAN, P20061 (See protein sequence)
Recommended Name: Transcobalamin-1 precursor  
Size: 433 amino acids; 48207 Da
3 PDB 3D structures from and Proteopedia for TCN1:
2CKV (3D)        4KKI (3D)        4KKJ (3D)    
Secondary accessions: A8KAC5 Q8WV77

Explore the universe of human proteins at neXtProt for TCN1: NX_P20061

Explore proteomics data for TCN1 at MOPED

Post-translational modifications: 

  • Contains about 30% carbohydrates1
  • Glycosylation2 at Asn160, Asn216, Asn316, Asn337, Asn343, Asn349, Asn354, Asn369

  • See TCN1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001053.2  
    ENSEMBL proteins: 
     ENSP00000257264  
    Reactome Protein details: P20061

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR002157 Cbl-bd_transpt_euk
     IPR027954 DUF4430

    Graphical View of Domain Structure for InterPro Entry P20061

    ProtoNet protein and cluster: P20061

    1 Blocks protein domain: IPB002157 Eukaryotic cobalamin-binding protein

    UniProtKB/Swiss-Prot: TCO1_HUMAN, P20061
    Similarity: Belongs to the eukaryotic cobalamin transport proteins family


    Find genes that share domains with TCN1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TCO1_HUMAN, P20061
    Function: Vitamin B12-binding protein. Transports cobalamin into cells

         Genatlas biochemistry entry for TCN1:
    transcobalamin 1 (vitamin B12 binding protein,R binder family),in secondary granules of mature neutrophils

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031419cobalamin binding IBA--
         
    Find genes that share ontologies with TCN1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TCN1:
     Cell cycle / mitosis defect 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TCN1

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TCO1_HUMAN, P20061: Secreted
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    cytoskeleton1
    cytosol1
    lysosome1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS--

    Find genes that share ontologies with TCN1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TCN1 About    
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1Defective BTD causes biotidinase deficiency
    Defective BTD causes biotidinase deficiency1.00
    Metabolism of vitamins and cofactors1.00
    Defective AMN causes hereditary megaloblastic anemia 11.00
    Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC1.00
    Defective MMAA causes methylmalonic aciduria type cblA1.00
    Defective MUT causes methylmalonic aciduria mut type1.00
    Defective CD320 causes methylmalonic aciduria1.00
    Defects in cobalamin (B12) metabolism1.00
    2Folate Metabolism
    Vitamin B12 Metabolism0.54
    3Metabolism
    Metabolism0.38
    4Disease
    Disease


    Find genes that share SuperPaths with TCN1           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for TCN1
        Vitamin B12 Metabolism

    1 Reactome Pathway for TCN1
        Cobalamin (Cbl, vitamin B12) transport and metabolism


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TCN1
    Interactions:

        GeneGlobe Interaction Network for TCN1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for TCN1 (ENSP000002572644) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CBLENSP000002640334STRING: ENSP00000264033
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006766vitamin metabolic process TAS--
    GO:0006767water-soluble vitamin metabolic process TAS--
    GO:0006824cobalt ion transport IEA--
    GO:0009235cobalamin metabolic process TAS--
    GO:0015889cobalamin transport IEA--

    Find genes that share ontologies with TCN1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for TCN1 (TCO1)

    3 HMDB Compounds for TCN1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Cobalamin5,6-dimethyl-1-a-D-ribofuranosylbenzimidazole (see all 15)13408-78-1--
    CobaltCo (see all 6)7440-48-4--
    CyanocobalaminDimethylbenzimidazoylcobamide (see all 92)68-19-9--

    2 DrugBank Compounds for TCN1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    CyanocobalaminCyanocob(III)alamin (see all 3)68-19-9transportersubstrate17259255 16047053
    HydroxocobalaminHydroxomin (see all 2)13422-51-0targetother6726060 844253

    9 Novoseek inferred chemical compound relationships for TCN1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    cobalamin 93.9 51 8988263 (2), 12881454 (2), 16384893 (2), 12356110 (1) (see all 32)
    vitamin b12 87.9 44 17990953 (2), 8689919 (2), 16613998 (2), 8172125 (2) (see all 25)
    cobinamide 87.1 1 11788601 (1)
    methylmalonic acid 81.4 1 17990953 (1)
    corrinoid 67.7 5 2070790 (3), 19299543 (1)
    methylcobalamin 56.3 1 7772517 (1)
    homocysteine 47.2 1 11259691 (1)
    cobalt 28.3 1 2070790 (1)
    methionine 13.2 1 16470748 (1)



    Find genes that share compounds with TCN1           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TCN1 gene: 
    NM_001062.3  

    Unigene Cluster for TCN1:

    Transcobalamin I (vitamin B12 binding protein, R binder family)
    Hs.2012  [show with all ESTs]
    Unigene Representative Sequence: NM_001062
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000529251 ENST00000257264(uc001noj.2) ENST00000532419 ENST00000534531
    ENST00000533734
    miRNA
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    Additional mRNA sequence: 

    AK292990.1 BC018632.1 J05068.1 

    4 DOTS entries:

    DT.411203  DT.102821453  DT.91709439  DT.99957312 

    Selected AceView cDNA sequences (see all 71):

    BM830340 BX281344 BM769834 BQ084191 CD723971 AA155640 BM769693 BM830954 
    NM_001062 BU675098 CB123040 BM769239 BP334292 BM855745 BP370727 BG779234 
    BE005813 J05068 AW604104 BC018632 AW337203 BI762019 BX480228 AW192630 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for TCN1    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9
    SP1:                                                                        
    SP2:              -                                                         
    SP3:                                      -     -                           


    ECgene alternative splicing isoforms for TCN1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TCN1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TCN1 Expression
    About this image


    TCN1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Blood (Hematopoietic System)
             Granulocytes Peripheral Blood
     
     Gall Bladder (Hepatobiliary System)
     
     Stomach (Gastrointestinal Tract)
    TCN1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TCN1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.2012

    UniProtKB/Swiss-Prot: TCO1_HUMAN, P20061
    Tissue specificity: Neutrophil granule protein

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TCN1 gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia TCN11 transcobalamin I (vitamin B12 binding protein, R binder more 77.06(n)
    63.28(a)
      612538  XM_850268.2  XP_855361.1 
    lizard
    (Anolis carolinensis)
    Reptilia TCN16
    transcobalamin I (vitamin B12 binding protein, R b...
    39(a)
    1 ↔ 1
    1(90842492-90860879)


    ENSEMBL Gene Tree for TCN1 (if available)
    TreeFam Gene Tree for TCN1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TCN1 gene
    GIF2  TCN22  
    1 SIMAP similar gene for TCN1 using alignment to 1 protein entry:     TCO1_HUMAN:
    GIF

    Find genes that share paralogs with TCN1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TCN1 (see all 384)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1919046761,2
    C--59619882(+) AGGGGA/GTGAGA 1 -- ds50010--------
    rs1162153071,2
    C,F--59619884(+) GGGATG/AAGATT 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1841579971,2
    --59619920(+) TTATGA/TATATG 1 -- ds50010--------
    rs800886711,2
    F--59619931(+) CCTCAC/TGTTTC 1 -- ds50011Minor allele frequency- T:0.03WA 118
    rs1125844731,2
    C,F--59619940(+) TCCCCC/TTTTCT 1 -- ds50012Minor allele frequency- T:0.02CSA WA 120
    rs1495028531,2
    --59619975(+) CACTAC/GCTGTA 1 -- ds50010--------
    rs802048951,2
    C,F--59620015(+) CTTGCA/CTCTGG 1 -- ds50011Minor allele frequency- C:0.03NA 120
    rs725617801,2
    C,F--59620113(-) CAACTG/CGGTAA 1 -- ds50015Minor allele frequency- C:0.01MN 404
    rs1114763001,2
    F--59620153(+) AACCTG/TGAGTA 1 -- ds50011Minor allele frequency- T:0.50CSA 6
    rs755791161,2
    F--59620173(+) TTATTA/TGACAT 1 -- ds50012Minor allele frequency- T:0.04CSA WA 120

    HapMap Linkage Disequilibrium report for TCN1 (59620273 - 59634048 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for TCN1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2659739CNV Deletion23128226
    nsv825935CNV Loss20364138
    nsv442233CNV CNV18776908

    Human Gene Mutation Database (HGMD): TCN1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TCN1
    DNA2.0 Custom Variant and Variant Library Synthesis for TCN1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 189905    OMIM disorders: --

    3 diseases for TCN1:    
    About MalaCards
    vitamin b12 deficiency    pernicious anemia    oral cancer

    3 diseases from the University of Copenhagen DISEASES database for TCN1:
    Vitamin B12 deficiency     Pernicious anemia     Megaloblastic anemia

    Find genes that share disorders with TCN1           About GenesLikeMe

    7 Novoseek inferred disease relationships for TCN1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    vitamin b12 deficiency 41.8 1 12356110 (1)
    myeloid leukemia chronic 29.2 1 8301203 (1)
    oral cancer 20.9 3 8820365 (2), 9587699 (1)
    hepatocellular carcinoma 0 1 10101589 (1)
    rheumatoid arthritis 0 3 1602292 (1), 2062181 (1)
    anemia 0 4 1602292 (1)
    tumors 0 1 18413759 (1)

    Genetic Association Database (GAD): TCN1
    Human Genome Epidemiology (HuGE) Navigator: TCN1 (21 documents)

    Export disorders for TCN1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TCN1 gene, integrated from 10 sources (see all 138):
    (articles sorted by number of sources associating them with TCN1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Study of four genes belonging to the folate pathway: transcobalamin 2 is involved in the onset of non-syndromic cleft lip with or without cleft palate. (PubMed id 16470748)1, 4, 9 Martinelli M....Carinci F. (Hum. Mutat. 2006)
    2. Associations of folate, vitamin B12, homocysteine, and folate-pathway polymorphisms with prostate-specific antigen velocity in men with localized prostate cancer. (PubMed id 20852008)1, 4 Collin S.M....Martin R.M. (amp 2010)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics. (PubMed id 20216556)1, 4 Garrod M.G....Miller J.W. (Eur J Clin Nutr 2010)
    5. Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations. (PubMed id 19303062)1, 4 Tanaka T....Ferrucci L. (Am. J. Hum. Genet. 2009)
    6. Integrative predictive model of coronary artery calcification in atherosclerosis. (PubMed id 19948975)1, 4 McGeachie M....Ramoni M.F. (Circulation 2009)
    7. Polymorphisms in DNA repair and one-carbon metabolism genes and overall survival in diffuse large B-cell lymphoma and follicular lymphoma. (PubMed id 18830263)1, 4 Wang S.S....Cerhan J.R. (Leukemia 2009)
    8. Folic acid use in pregnancy and embryo selection. (PubMed id 18485163)1, 4 Haggarty P....McNeill G. (BJOG 2008)
    9. One-carbon metabolism gene polymorphisms and risk of non-Hodgkin lymphoma in Australia. (PubMed id 17891500)1, 4 Lee K.M....Armstrong B.K. (Hum. Genet. 2007)
    10. Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. (PubMed id 16740002)1, 2 Ramachandran P....Loo J.A. (J. Proteome Res. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6947 HGNC: 11652 AceView: TCN1 Ensembl:ENSG00000134827 euGenes: HUgn6947
    ECgene: TCN1 H-InvDB: TCN1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TCN1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TCN1 gene:
    Search GeneIP for patents involving TCN1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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