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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TCHP Gene

protein-coding   GIFtS: 51
GCID: GC12P110338

Trichoplein, Keratin Filament Binding

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Trichoplein, Keratin Filament Binding1 2     TpMs2
mitostatin1 2     Trichoplein Keratin Filament-Binding Protein2
Mitochondrial Protein With Oncostatic Activity2 3     Mitostatin3
Tumor Suppressor Protein2 3     Protein TCHP3

External Ids:    HGNC: 281351   Entrez Gene: 842602   Ensembl: ENSG000001394377   OMIM: 6126545   UniProtKB: Q9BT923   

Export aliases for TCHP gene to outside databases

Previous GC identifers: GC12P108802 GC12P107354


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TCHP Gene: 
TCHP (trichoplein, keratin filament binding) is a protein-coding gene. Diseases associated with TCHP include intermittent claudication, and velocardiofacial syndrome, and among its related super-pathways are Cytoskeleton remodeling Keratin filaments. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: TCHP_HUMAN, Q9BT92
Function: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress.
Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its
phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May
regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple
epithelial cells

Gene Wiki entry for TCHP Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_009775.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TCHP gene promoter:
         RFX1   STAT5A   LUN-1   Pax-4a   GATA-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTCHP promoter sequence
   Search SABiosciences Chromatin IP Primers for TCHP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCHP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.11   Ensembl cytogenetic band:  12q24.11   HGNC cytogenetic band: 12q24.11

TCHP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCHP gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P110338:  view genomic region     (about GC identifiers)

Start:
110,338,069 bp from pter      End:
110,421,646 bp from pter
Size:
83,578 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TCHP_HUMAN, Q9BT92 (See protein sequence)
Recommended Name: Trichoplein keratin filament-binding protein  
Size: 498 amino acids; 61072 Da
Subunit: Interacts specifically with keratin proteins including, KRT5, KRT6A, KRT8, KRT14, KRT16 and KRT18
Subcellular location: Cytoplasm, cytoskeleton. Cytoplasm. Cell membrane. Mitochondrion
Secondary accessions: Q8NAG0

Explore the universe of human proteins at neXtProt for TCHP: NX_Q9BT92

Explore proteomics data for TCHP at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BT92

  • TCHP Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TCHP Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001137324.1  NP_115676.1  

    ENSEMBL proteins: 
     ENSP00000440838   ENSP00000384520   ENSP00000324404   ENSP00000441835  

    Human Recombinant Protein Products for TCHP: 
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    Novus Biologicals TCHP Lysates
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TCHP 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion IDA18931701
    GO:0005813centrosome IDA--
    GO:0005886plasma membrane IDA--
    GO:0045095keratin filament IDA15731013

    TCHP for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for TCHP


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026773 TCHP/CCDC11

    Graphical View of Domain Structure for InterPro Entry Q9BT92

    ProtoNet protein and cluster: Q9BT92

    UniProtKB/Swiss-Prot: TCHP_HUMAN, Q9BT92
    Similarity: Belongs to the TCHP family


    TCHP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TCHP_HUMAN, Q9BT92
    Function: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress.
    Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its
    phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May
    regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple
    epithelial cells

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI15731013
         
    TCHP for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for TCHP:
     Increased S DNA content, incre  Small cells 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TCHP 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TCHP

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TCHP 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TCHP 

    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate TCHP:
    hsa-miR-1290 hsa-miR-612 hsa-miR-3122 hsa-miR-330-5p hsa-miR-3913-5p hsa-miR-326 hsa-miR-3674 hsa-miR-1285
    SwitchGear 3'UTR luciferase reporter plasmidTCHP 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TCHP About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Cytoskeleton remodeling Keratin filaments
    Cytoskeleton remodeling Keratin filaments0.91

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for TCHP
        Cytoskeleton remodeling Keratin filaments


    1 GeneGo (Thomson Reuters) Pathway for TCHP
        Cytoskeleton remodeling Keratin filaments




    TCHP for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TCHP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/13 Interacting proteins for TCHP (Q9BT922, 3 ENSP000003244044) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CCDC85BQ158342, 3, ENSP000003116954MINT-67296 I2D: score=5 STRING: ENSP00000311695
    KRT15P190122, 3, ENSP000002540434MINT-66456 I2D: score=5 STRING: ENSP00000254043
    NME7Q9Y5B82, 3, ENSP000003567854MINT-67218 I2D: score=5 STRING: ENSP00000356785
    TEX11Q8IYF32, 3, ENSP000003409954MINT-67777 I2D: score=5 STRING: ENSP00000340995
    VIMP086702, 3, ENSP000002242374MINT-66106 I2D: score=5 STRING: ENSP00000224237
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IDA18931701
    GO:0030308negative regulation of cell growth IDA18931701

    TCHP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TCHP

    Search CenterWatch for drugs/clinical trials and news about TCHP

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TCHP gene (2 alternative transcripts): 
    NM_001143852.1  NM_032300.4  

    Unigene Cluster for TCHP:

    Trichoplein, keratin filament binding
    Hs.410924  [show with all ESTs]
    Unigene Representative Sequence: NM_032300
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000537218 ENST00000544838(uc001tpo.1) ENST00000405876(uc001tpn.3)
    ENST00000312777(uc001tpp.3) ENST00000536408 ENST00000549550 ENST00000551627
    ENST00000537880 ENST00000549524 ENST00000550780
    miRNA
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    8 QIAGEN miScript miRNA Assays for microRNAs that regulate TCHP:
    hsa-miR-1290 hsa-miR-612 hsa-miR-3122 hsa-miR-330-5p hsa-miR-3913-5p hsa-miR-326 hsa-miR-3674 hsa-miR-1285
    SwitchGear 3'UTR luciferase reporter plasmidTCHP 3' UTR sequence
    Inhib. RNA
    Products:
         
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TCHP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCHP
    Sirion Biotech Customized lentivirus for stable overexpression of TCHP 
                         Customized lentivirus expression plasmids for stable overexpression of TCHP 
    Primer
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    OriGene qPCR primer pairs and template standards for TCHP
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TCHP
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TCHP

    Additional mRNA sequence: 

    AK000079.1 AK301262.1 AY007230.1 AY210413.1 BC004285.1 BC022838.1 BX648596.1 

    7 DOTS entries:

    DT.406404  DT.100749675  DT.121146483  DT.91822531  DT.95187472  DT.91691330  DT.411965 

    24/98 AceView cDNA sequences (see all 98):

    BU163267 NM_032300 BX097816 AW672786 CK902166 AK092736 AI589290 AA736767 
    AW136783 AY007230 BC022838 AI733413 AA923604 AK000079 BG681703 BC004285 
    BU622721 AX747696 AI791723 CK902165 BQ631775 BM541692 AI822006 BE465774 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TCHP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCTCTGTTG
    TCHP Expression
    About this image


    See TCHP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TCHP

    SOURCE GeneReport for Unigene cluster: Hs.410924

    UniProtKB/Swiss-Prot: TCHP_HUMAN, Q9BT92
    Tissue specificity: Expressed at high levels in normal urothelial and breast epithelial cells. Also expressed in
    the smooth muscle and endothelial cells. Reduced expression seen in advanced bladder and breast carcinomas (at
    protein level). Ubiquitous. Expressed at highest levels in the heart, skeletal muscle, kidney, liver and testis

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCHP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TCHP gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tchp1 , 5 trichoplein, keratin filament binding1, 5 80.95(n)1
    77.46(a)1
      5 (55.99 cM)5
    778321  NM_029992.21  NP_084268.21 
     1147077605 
    chicken
    (Gallus gallus)
    Aves LOC4252091 trichoplein keratin filament-binding protein-like 63.81(n)
    60.66(a)
      425209  XM_422992.3  XP_422992.3 
    African clawed frog
    (Xenopus laevis)
    Amphibia BC042932.12   -- 72.09(n)    BC042932.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tchp1 trichoplein, keratin filament binding 60.97(n)
    56.34(a)
      678595  NM_001040343.1  NP_001035433.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG172306
    CG73526
    --
    17(a)
    14(a)
    many ↔ many
    many ↔ many
    3R(7263507-7291360)
    3R(4173301-4175018)


    ENSEMBL Gene Tree for TCHP (if available)
    TreeFam Gene Tree for TCHP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/518 SNPs in TCHP are shown (see all 518)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0640564
    A gastric carcinoma sample4--see VAR_0640562 S P mis40--------
    VAR_0640574
    A pancreatic carcinoma sample4--see VAR_0640572 E K mis40--------
    rs1435299781,2
    --110336109(+) TCCTCA/GGTTGA 1 -- us2k10--------
    rs1923610521,2
    --110336146(+) AGTAGC/GTGGGA 1 -- us2k10--------
    rs1844600471,2
    --110336172(+) ACCACA/GCCCAG 1 -- us2k10--------
    rs110688241,2
    C--110336245(+) CCTGAC/TCTCAA 1 -- us2k16Minor allele frequency- T:0.20WA CSA NA EA 363
    rs1134546901,2
    C,F--110336258(+) GATCCG/ACCAGC 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs789425841,2
    --110336343(+) TCATTA/CCATGG 2 -- us2k10--------
    rs1492516311,2
    --110336351(+) TGGACC/TAGGAA 2 -- us2k10--------
    rs1444262261,2
    C--110336372(+) AGACAA/GATGAA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TCHP (110338069 - 110421646 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TCHP: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TCHP
    DNA2.0 Custom Variant and Variant Library Synthesis for TCHP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612654    OMIM disorders: --

    9 diseases for TCHP:    About MalaCards
    intermittent claudication    velocardiofacial syndrome    digeorge syndrome    thyroid cancer
    thyroiditis    prostate cancer    prostatitis    endotheliitis
    breast cancer


    TCHP for disorders           About GeneDecksing


    Export disorders for TCHP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TCHP gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with TCHP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of trichoplein, a novel keratin filament-binding protein. (PubMed id 15731013)1, 2, 3, 9 Nishizawa M.... Inagaki M. (2005)
    2. Trichoplein/mitostatin regulates endoplasmic reticulu m-mitochondria juxtaposition. (PubMed id 20930847)1, 3 Cerqua C....Scorrano L. (2010)
    3. MITOSTATIN, a putative tumor suppressor on chromosome 12q24.1, is downregulated in human bladder and breast cancer. (PubMed id 18931701)1, 2 Vecchione A....Baffa R. (2009)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid. (PubMed id 23319000)1 Luykx J.J....Ophoff R.A. (2013)
    6. Trichoplein controls microtubule anchoring at the cen trosome by binding to Odf2 and ninein. (PubMed id 21325031)1 Ibi M....Inagaki M. (2011)
    7. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    9. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
    10. Fundamentals of ICANL accreditation. (PubMed id 15731016)1 Katanick S.L. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 84260 HGNC: 28135 AceView: MGC10854 Ensembl:ENSG00000139437 euGenes: HUgn84260
    ECgene: TCHP H-InvDB: TCHP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TCHP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TCHP gene:
    Search GeneIP for patents involving TCHP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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