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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TCF25 Gene

protein-coding   GIFtS: 53
GCID: GC16P089939

Transcription Factor 25 (Basic Helix-Loop-Helix)

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transcription Factor 25 (Basic Helix-Loop-Helix)1 2     Hulp12
NULP12 3 5     PRO26202
Nuclear Localized Protein 12 3     hKIAA10492
TCF-252 3     Transcription Factor 252
KIAA10493 5     

External Ids:    HGNC: 291811   Entrez Gene: 229802   Ensembl: ENSG000001410027   OMIM: 6123265   UniProtKB: Q9BQ703   

Export aliases for TCF25 gene to outside databases

Previous GC identifers: GC16P088469 GC16P075633


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TCF25 Gene:
TCF25 is a member of the basic helix-loop-helix (bHLH) family of transcription factors that are important in
embryonic development (Steen and Lindholm, 2008 (PubMed 18068114)).(supplied by OMIM, Sep 2008)

GeneCards Summary for TCF25 Gene: 
TCF25 (transcription factor 25 (basic helix-loop-helix)) is a protein-coding gene. Diseases associated with TCF25 include osteosarcoma. GO annotations related to this gene include DNA binding and sequence-specific DNA binding transcription factor activity.

UniProtKB/Swiss-Prot: TCF25_HUMAN, Q9BQ70
Function: May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress
transcription of SRF in vitro and so may play a role in heart development




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NT_010542.15  NC_018927.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TCF25 gene promoter:
         AP-1   Pax-6   Pax-2   Pax-2a   AP-2gamma   GATA-2   AP-2beta   AP-2alpha   AP-2alphaA   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTCF25 promoter sequence
   Search SABiosciences Chromatin IP Primers for TCF25

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCF25


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24.3   Ensembl cytogenetic band:  16q24.3   HGNC cytogenetic band: 16q24.3

TCF25 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCF25 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P089939:  view genomic region     (about GC identifiers)

Start:
89,939,994 bp from pter      End:
89,977,792 bp from pter
Size:
37,799 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TCF25_HUMAN, Q9BQ70 (See protein sequence)
Recommended Name: Transcription factor 25  
Size: 676 amino acids; 76667 Da
Subunit: Interacts with XIAP (By similarity)
Subcellular location: Nucleus. Note=Some staining in the cytosol
Secondary accessions: Q2MK75 Q9UPV3

Explore the universe of human proteins at neXtProt for TCF25: NX_Q9BQ70

Explore proteomics data for TCF25 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BQ70

  • TCF25 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TCF25 Protein Expression
    REFSEQ proteins: NP_055787.1  
    ENSEMBL proteins: 
     ENSP00000456803   ENSP00000263346   ENSP00000456080   ENSP00000454414   ENSP00000457329  
     ENSP00000456592   ENSP00000455611   ENSP00000456840   ENSP00000456344   ENSP00000455471  
     ENSP00000263347  

    Human Recombinant Protein Products for TCF25: 
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    Novus Biologicals TCF25 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TCF25 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA16574069
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005739mitochondrion IDA--

    TCF25 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR006994 TCF25
     IPR011990 TPR-like_helical

    Graphical View of Domain Structure for InterPro Entry Q9BQ70

    ProtoNet protein and cluster: Q9BQ70

    1 Blocks protein domain: IPB006994 Protein of unknown function DUF654

    UniProtKB/Swiss-Prot: TCF25_HUMAN, Q9BQ70
    Domain: The C-terminal region mediates transcriptional repression
    Similarity: Belongs to the TCF25 family


    TCF25 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TCF25_HUMAN, Q9BQ70
    Function: May play a role in cell death control. Acts as a transcriptional repressor. Has been shown to repress
    transcription of SRF in vitro and so may play a role in heart development

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IDA16574069
    GO:0005515protein binding IPI16189514
         
    TCF25 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TCF25 
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TCF25 
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TCF25

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/7 Interacting proteins for TCF25 (Q9BQ701, 2, 3 ENSP000002633464) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SAT1P216731, 3, ENSP000003685724EBI-745182,EBI-711613 I2D: score=5 STRING: ENSP00000368572
    NEK2P519552, 3MINT-8263753 I2D: score=2 
    RPS10P467832, 3, ENSP000003472714MINT-8269274 I2D: score=2 STRING: ENSP00000347271
    MAGEA11P433643, ENSP000003473584I2D: score=4 STRING: ENSP00000347358
    MSNP260383I2D: score=4 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IDA16574069
    GO:0006351transcription, DNA-dependent IEA--
    GO:0007507heart development NAS16574069

    TCF25 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TCF25

    Search CenterWatch for drugs/clinical trials and news about TCF25

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TCF25 gene: 
    NM_014972.2  

    Unigene Cluster for TCF25:

    Transcription factor 25 (basic helix-loop-helix)
    Hs.415342  [show with all ESTs]
    Unigene Representative Sequence: AK095785
    18/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24):
    ENST00000561585(uc010vpp.1) ENST00000561958 ENST00000263346(uc002fpb.2)
    ENST00000563032 ENST00000564652 ENST00000565196 ENST00000568412 ENST00000563406
    ENST00000565404 ENST00000566751 ENST00000562256(uc002fpc.2) ENST00000568409
    ENST00000568870 ENST00000562184 ENST00000563636 ENST00000566158 ENST00000570116(uc002fpd.1)
    ENST00000562193
    miRNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TCF25

    Additional mRNA sequence: 

    AB028972.1 AF130092.1 AF322111.1 AK024679.1 AK095785.1 AK127949.1 AK301053.1 BC000959.1 
    BC009349.2 BC011884.2 DQ321703.1 

    24/49 DOTS entries (see all 49):

    DT.100829193  DT.97762530  DT.447946  DT.95164481  DT.100876972  DT.100876982  DT.40229577  DT.120720636 
    DT.91867737  DT.100876980  DT.100876971  DT.95164476  DT.95211999  DT.100876977  DT.97810093  DT.100876989 
    DT.92410112  DT.95105563  DT.100038028  DT.95242185  DT.95114896  DT.97827770  DT.427850  DT.91749653 

    24/339 AceView cDNA sequences (see all 339):

    AI042046 BU558002 BF352465 AA403210 AI287848 BG010273 BU535465 BF063423 
    BP355176 CB852868 AI343837 BI764550 CR623529 BI869549 AI688142 AI337983 
    BX098654 CB215161 BQ959783 BM705382 BX380107 CA425965 BX417814 AA722509 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for TCF25 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b ^ 13a · 13b ^ 14a · 14b · 14c · 14d ^ 15 ^ 16a · 16b ^ 17a ·
    SP1:                    -                                                                                   -     -                 -                 -     -   
    SP2:                                                                                                        -     -                 -                 -     -   
    SP3:                    -                             -                                                                                                         
    SP4:                                                                                                        -     -                                             
    SP5:                    -           -     -     -     -     -     -     -     -     -     -                 -     -                                             

    ExUns: 17b ^ 18 ^ 19a · 19b ^ 20
    SP1:        -     -               
    SP2:              -               
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for TCF25

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TCF25 expression in normal human tissues (normalized intensities)      TCF25 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGGCCAACT
    TCF25 Expression
    About this image


    TCF25 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             Medulla Oblongata
             ganglion/cranial/facial VII   
     
     Peripheral Nervous System (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Spinal Cord (Nervous System)
             spinal/ganglion/dorsal root ganglion   
     
     Neural Tube (Nervous System)
             Spinal Ventral Columns
     
     Eye (Sensory Organs)
             Retina

    See TCF25 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TCF25

    SOURCE GeneReport for Unigene cluster: Hs.415342

    UniProtKB/Swiss-Prot: TCF25_HUMAN, Q9BQ70
    Tissue specificity: In the embryo, widely expressed with highest levels in brain. In the adult, highest expression
    is found in the heart

        SABiosciences Custom PCR Arrays for TCF25
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCF25

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TCF25 gene from 10/21 species (see all 21)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tcf251 , 5 transcription factor 25 (basic helix-loop-helix)1, 5 85.9(n)1
    90.38(a)1
      8 (72.10 cM)5
    668551  NM_001037878.21  NP_001032967.11 
     1233738245 
    chicken
    (Gallus gallus)
    Aves TCF251 transcription factor 25 (basic helix-loop-helix) 68.38(n)
    64.09(a)
      425450  XM_423211.3  XP_423211.3 
    lizard
    (Anolis carolinensis)
    Reptilia TCF256
    transcription factor 25 (basic helix-loop-helix)
    58(a)
    1 ↔ 1
    GL343866.1(16135-53259)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.237892 Xenopus laevis transcribed sequence with moderate similarity more 73.3(n)    CD360664.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc09e072 Transcribed sequence with weak similarity to protein more 72.43(n)    BQ450467.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG79271 CG7927 49.25(n)
    41.07(a)
      38897  NM_139917.2  NP_648174.3 
    worm
    (Caenorhabditis elegans)
    Secernentea K07A12.16
    Protein K07A12.1
    23(a)
    1 ↔ 1
    I(8666594-8669788)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes (YDR333C)4 Putative protein of unknown function   --   4(1135431-1133260) 851933  NP_010620.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G469001 hypothetical protein 42.69(n)
    28.81(a)
      819303  NM_130257.4  NP_566090.1 
    rice
    (Oryza sativa)
    Liliopsida Os09g05149001 hypothetical protein 43.34(n)
    29.67(a)
      4347571  NM_001070198.1  NP_001063663.1 


    ENSEMBL Gene Tree for TCF25 (if available)
    TreeFam Gene Tree for TCF25 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TCF25 gene
    1 SIMAP similar gene for TCF25 using alignment to 11 protein entries:     TCF25_HUMAN (see all proteins):
    NULP1

    TCF25 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1329 SNPs in TCF25 are shown (see all 1329)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
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    ----------
    rs1829489191,2
    --89938244(+) ATACAC/TAGCTC 1 -- us2k10--------
    rs728134281,2
    C,F--89938333(+) GCCTGC/TGGGAG 1 -- us2k12Minor allele frequency- T:0.03WA NA 238
    rs1455533701,2
    --89938373(+) AATCCA/CAACAC 1 -- us2k10--------
    rs795417071,2
    F--89938377(+) CAAACA/TCACAA 1 -- us2k11Minor allele frequency- T:0.02NA 120
    rs43905921,2
    C,F,A,H--89938438(+) TTCACG/AGACTC 1 -- us2k15Minor allele frequency- A:0.01EA NS WA 610
    rs1887360451,2
    --89938527(+) GCCAGC/TAATAA 1 -- us2k10--------
    rs1468031701,2
    --89938645(+) ATGAAA/GGCCCA 1 -- us2k10--------
    rs793396491,2
    C,F--89938650(+) AGCCCG/ACGTTA 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1456212361,2
    --89938652(+) CCCACA/GTTAAA 1 -- us2k10--------
    rs1481767741,2
    C--89938663(+) ACCCTA/GAACCA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TCF25 (89939994 - 89977792 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/24 variations for TCF25 (see all 24):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1528431CNV Deletion17803354
    esv5359CNV Deletion18987735
    esv2665192CNV Deletion23128226
    esv1411513CNV Deletion17803354
    esv1230447CNV Deletion17803354
    esv1404867CNV Deletion17803354
    nsv509640CNV Insertion20534489
    nsv907442CNV Loss21882294
    dgv3009n71CNV Loss21882294
    nsv9481CNV Loss18304495

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612326    OMIM disorders: --

    2 diseases for TCF25:    About MalaCards
    osteosarcoma    


    TCF25 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TCF25
    Human Genome Epidemiology (HuGE) Navigator: TCF25 (2 documents)

    Export disorders for TCF25 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TCF25 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with TCF25)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. hnulp1, a basic helix-loop-helix protein with a novel transcriptional repressive domain, inhibits transcriptional activity of serum response factor. (PubMed id 16574069)1, 2, 3 Cai Z....Wu X. (2006)
    2. Assessment of a polymorphism of SDK1 with hypertensio n in Japanese Individuals. (PubMed id 19851296)1, 4 Oguri M....Yamada Y. (2010)
    3. Association of genetic variants with hemorrhagic stro ke in Japanese individuals. (PubMed id 20198315)1, 4 Yoshida T....Yamada Y. (2010)
    4. Nuclear localized protein-1 (Nulp1) increases cell death of human osteosarcoma cells and binds the X-linked inhibitor of apoptosis protein. (PubMed id 18068114)1, 2 Steen H. and Lindholm D. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Nulp1, a novel basic helix-loop-helix protein expressed broadly during early embryonic organogenesis and prominently in developing dorsal root ganglia. (PubMed id 12107429)1, 3 Olsson M....Hjalt T. (2002)
    7. Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10470851)1, 2 Kikuno R....Ohara O. (1999)
    8. Quantitative analysis of HSP90-client interactions rev eals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (2012)
    9. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 22980 HGNC: 29181 AceView: KIAA1049 Ensembl:ENSG00000141002 euGenes: HUgn22980
    ECgene: TCF25 H-InvDB: TCF25

    (According to HUGE)
    About This Section
    HUGE: KIAA1049

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TCF25 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TCF25 gene:
    Search GeneIP for patents involving TCF25

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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