Aliases for TCF20 Gene
External Ids for TCF20 Gene
Previous GeneCards Identifiers for TCF20 Gene
This gene encodes a transcription factor that recognizes the platelet-derived growth factor-responsive element in the matrix metalloproteinase 3 promoter. The encoded protein is thought to be a transcriptional coactivator, enhancing the activity of transcription factors such as JUN and SP1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
GeneCards Summary for TCF20 Gene
TCF20 (Transcription Factor 20 (AR1)) is a Protein Coding gene. Diseases associated with TCF20 include pseudosarcomatous fibromatosis. Among its related pathways are ERK Signaling and ERK Signaling. GO annotations related to this gene include transcription coactivator activity. An important paralog of this gene is RAI1.
UniProtKB/Swiss-Prot for TCF20 Gene
Transcriptional activator that binds to the regulatory region of MMP3 and thereby controls stromelysin expression. It stimulates the activity of various transcriptional activators such as JUN, SP1, PAX6 and ETS1, suggesting a function as a coactivator