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Aliases for TCERG1L Gene

Aliases for TCERG1L Gene

  • Transcription Elongation Regulator 1 Like 2 3 5
  • Transcription Elongation Regulator 1-Like 2
  • 5730476P14Rik 3

External Ids for TCERG1L Gene

Previous GeneCards Identifiers for TCERG1L Gene

  • GC10M132365
  • GC10M132780
  • GC10M132890
  • GC10M126465

Summaries for TCERG1L Gene

GeneCards Summary for TCERG1L Gene

TCERG1L (Transcription Elongation Regulator 1 Like) is a Protein Coding gene. An important paralog of this gene is PRPF40A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCERG1L Gene

Genomics for TCERG1L Gene

Regulatory Elements for TCERG1L Gene

Genomic Location for TCERG1L Gene

131,092,391 bp from pter
131,311,721 bp from pter
219,331 bases
Minus strand

Genomic View for TCERG1L Gene

Genes around TCERG1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TCERG1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TCERG1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCERG1L Gene

Proteins for TCERG1L Gene

  • Protein details for TCERG1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transcription elongation regulator 1-like protein
    Protein Accession:
    Secondary Accessions:
    • Q5VWI2
    • Q86XM8

    Protein attributes for TCERG1L Gene

    586 amino acids
    Molecular mass:
    65660 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH42951.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH93639.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI01536.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for TCERG1L Gene

Proteomics data for TCERG1L Gene at MOPED

Post-translational modifications for TCERG1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TCERG1L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TCERG1L Gene

Domains & Families for TCERG1L Gene

Protein Domains for TCERG1L Gene


Suggested Antigen Peptide Sequences for TCERG1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 FF domains.
  • Contains 2 FF domains.
  • Contains 2 WW domains.
genes like me logo Genes that share domains with TCERG1L: view

No data available for Gene Families for TCERG1L Gene

Function for TCERG1L Gene

genes like me logo Genes that share phenotypes with TCERG1L: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TCERG1L Gene

Localization for TCERG1L Gene

Subcellular locations from

Jensen Localization Image for TCERG1L Gene COMPARTMENTS Subcellular localization image for TCERG1L gene
Compartment Confidence
nucleus 3
cytosol 2
endoplasmic reticulum 1
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TCERG1L Gene

Pathways & Interactions for TCERG1L Gene

SuperPathways for TCERG1L Gene

No Data Available

Interacting Proteins for TCERG1L Gene

Gene Ontology (GO) - Biological Process for TCERG1L Gene


No data available for Pathways by source and SIGNOR curated interactions for TCERG1L Gene

Drugs & Compounds for TCERG1L Gene

No Compound Related Data Available

Transcripts for TCERG1L Gene

mRNA/cDNA for TCERG1L Gene

(3) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(18) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TCERG1L Gene

Transcription elongation regulator 1-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TCERG1L Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15
SP1: - - -

Relevant External Links for TCERG1L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TCERG1L Gene

mRNA expression in normal human tissues for TCERG1L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TCERG1L Gene

This gene is overexpressed in Thyroid (x10.6), Brain - Cortex (x6.9), Brain - Frontal Cortex (BA9) (x6.8), and Brain - Anterior cingulate cortex (BA24) (x6.5).

Protein differential expression in normal tissues from HIPED for TCERG1L Gene

This gene is overexpressed in Breast (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TCERG1L Gene

SOURCE GeneReport for Unigene cluster for TCERG1L Gene Hs.126575

genes like me logo Genes that share expression patterns with TCERG1L: view

Protein tissue co-expression partners for TCERG1L Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for TCERG1L Gene

Orthologs for TCERG1L Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TCERG1L Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC101906614 35
  • 70.83 (n)
  • 62.08 (a)
(Canis familiaris)
Mammalia TCERG1L 35
  • 83.72 (n)
  • 81.26 (a)
  • 80 (a)
(Mus musculus)
Mammalia Tcerg1l 35
  • 81.41 (n)
  • 80.4 (a)
Tcerg1l 16
Tcerg1l 36
  • 80 (a)
(Pan troglodytes)
Mammalia TCERG1L 35
  • 98.63 (n)
  • 98.12 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Tcerg1l 35
  • 82.02 (n)
  • 81.28 (a)
(Monodelphis domestica)
Mammalia TCERG1L 36
  • 64 (a)
(Ornithorhynchus anatinus)
Mammalia TCERG1L 36
  • 80 (a)
(Gallus gallus)
Aves TCERG1L 35
  • 71.53 (n)
  • 68.67 (a)
  • 60 (a)
(Anolis carolinensis)
Reptilia TCERG1L 36
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tcerg1l 35
  • 64.49 (n)
  • 59.66 (a)
(Danio rerio)
Actinopterygii LOC101886358 35
  • 62.19 (n)
  • 61.87 (a)
  • 63 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG42724 36
  • 13 (a)
(Caenorhabditis elegans)
Secernentea tcer-1 36
  • 14 (a)
ZK1127.6 36
  • 9 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PRP40 36
  • 8 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8543 36
  • 21 (a)
Species with no ortholog for TCERG1L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TCERG1L Gene

Gene Tree for TCERG1L (if available)
Gene Tree for TCERG1L (if available)

Paralogs for TCERG1L Gene

Paralogs for TCERG1L Gene

(1) SIMAP similar genes for TCERG1L Gene using alignment to 1 proteins: Pseudogenes for TCERG1L Gene

genes like me logo Genes that share paralogs with TCERG1L: view

Variants for TCERG1L Gene

Sequence variations from dbSNP and Humsavar for TCERG1L Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs17857275 - 131,163,140(+) GCACC(A/G/T)GGGTG reference, missense
VAR_037602 A colorectal cancer sample
rs17857276 - 131,098,325(+) AGATT(C/T)CTCTA reference, missense
VAR_037604 -
rs750819 -- 131,172,725(+) CAGCC(A/G)TGATG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TCERG1L Gene

Variant ID Type Subtype PubMed ID
nsv428242 CNV Gain 18775914
nsv470974 CNV Gain 18288195
nsv832027 CNV Gain 17160897
nsv896111 CNV Loss 21882294
nsv7621 CNV Loss 18451855
esv2743526 CNV Deletion 23290073
esv2743527 CNV Deletion 23290073
nsv511463 CNV Loss 21212237
esv26490 CNV Loss 19812545
nsv512193 CNV Loss 21212237
dgv182n67 CNV Loss 20364138
esv3237 CNV Deletion 18987735
esv2743528 CNV Deletion 23290073
esv6315 CNV Loss 19470904
dgv175e199 CNV Deletion 23128226
nsv498745 CNV Loss 21111241
nsv820144 CNV Loss 19587683
esv32814 CNV Gain+Loss 17666407
nsv825646 CNV Loss 20364138
nsv825647 CNV Loss 20364138
nsv896112 CNV Loss 21882294
nsv896113 CNV Loss 21882294
esv2580680 CNV Insertion 19546169
esv1161251 CNV Insertion 17803354
esv1596333 CNV Insertion 17803354
dgv176e199 CNV Deletion 23128226
esv1008219 CNV Deletion 20482838
esv23166 CNV Loss 19812545
esv2743529 CNV Deletion 23290073
esv2677389 CNV Deletion 23128226
nsv832028 CNV Loss 17160897
esv27895 CNV Gain 19812545
esv2743531 CNV Deletion 23290073
esv1452199 CNV Deletion 17803354
esv2743532 CNV Deletion 23290073
esv2743533 CNV Deletion 23290073
esv2743534 CNV Deletion 23290073
nsv7622 CNV Insertion 18451855
nsv825648 CNV Gain 20364138
esv2743535 CNV Deletion 23290073
esv2743536 CNV Deletion 23290073
esv28224 CNV Loss 19812545
esv2743537 CNV Deletion 23290073
nsv25335 CNV Loss 16902084
nsv825649 CNV Gain 20364138
esv2664001 CNV Deletion 23128226
nsv509375 CNV Insertion 20534489

Variation tolerance for TCERG1L Gene

Residual Variation Intolerance Score: 85.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.26; 52.84% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TCERG1L Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TCERG1L Gene

Disorders for TCERG1L Gene

Relevant External Links for TCERG1L

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TCERG1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TCERG1L Gene

Publications for TCERG1L Gene

  1. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. (PMID: 22412388) Kenny E.E. … Peter I. (PLoS Genet. 2012) 3 48 67
  2. Panorama of ancient metazoan macromolecular complexes. (PMID: 26344197) Wan C. … Emili A. (Nature 2015) 3
  3. Genome-wide association study identifies novel loci association with fasting insulin and insulin resistance in African Americans. (PMID: 22791750) Chen G. … Rotimi C. (Hum. Mol. Genet. 2012) 3
  4. A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. (PMID: 22832960) Service S.K. … Freimer N.B. (Transl Psychiatry 2012) 3
  5. Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. (PMID: 21490949) Sim X. … Tai E.S. (PLoS Genet. 2011) 3

Products for TCERG1L Gene

Sources for TCERG1L Gene

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