TCERG1L Gene
protein-coding GIFtS : 43
GCID: GC10 M132890
transcription elongation regulator 1-like
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Aliasesfor TCERG1L gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Transcription Elongation Regulator 1-Like 1 2 FLJ389501 5730476P14Rik2 Transcription Elongation Regulator 1-Like Protein2
Export aliases for TCERG1L gene to outside databases Previous GC identifers: GC10M132365 GC10M132780 GC10M126465
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Summariesfor TCERG1L gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor TCERG1L gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000010.10 NC_018921.1 NT_008818.16 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the TCERG1L gene promoter: HOXA3 POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 C/EBPalpha AREB6 c-Myb Cart-1 Other transcription factors Search SABiosciences Chromatin IP Primers for TCERG1L Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCERG1L
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 10q26.3 Ensembl cytogenetic band: 10q26.3 HGNC cytogenetic band: 10q26.3 TCERG1L Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 10 GeneLoc Exon Structure
GeneLoc location for GC10M132890: view genomic region
(about GC identifiers )
Start:
132,890,654 bp from pter
End:
133,109,984 bp from pter
Size:
219,331 bases
Orientation:
minus strand
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Proteinsfor TCERG1L gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: TCRGL_HUMAN, Q5VWI1 (See
protein sequence )Recommended Name: Transcription elongation regulator 1-like protein Size : 586 amino acids; 65660 Da
Sequence caution : Sequence=AAH42951.1; Type=Erroneous initiation; Sequence=AAH93639.1; Type=Erroneous initiation;Sequence=AAI01536.1; Type=Erroneous initiation;
Secondary accessions : Q5VWI2 Q86XM8Explore the universe of human proteins at neXtProt for TCERG1L: NX_Q5VWI1 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q5VWI1 TCERG1L Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_777597.2 ENSEMBL proteins: ENSP00000357631 Human Recombinant Protein Products: TCERG1L Antibody Products: Assay Products for TCERG1L:
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Protein
Domains / Familiesfor TCERG1L gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
TCERG1L for domains About GeneDecksing 2 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q5VWI1 ProtoNet protein and cluster: Q5VWI1
UniProtKB/Swiss-Prot: TCRGL_HUMAN, Q5VWI1 Similarity : Contains 2 FF domainsSimilarity : Contains 2 WW domains
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Functionfor TCERG1L gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for TCERG1L (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for TCERG1L (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: TCERG1L (NM_174937 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TCERG1L Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat TCERG1L
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCERG1L
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Pathways & Interactionsfor TCERG1L gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TCERG1L
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Drugs & Compoundsfor TCERG1L gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for TCERG1L Search CenterWatch for drugs/clinical trials and news about TCERG1L / TCRGL
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Transcriptsfor TCERG1L gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
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SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for TCERG1L gene: NM_174937.3 Unigene Cluster for TCERG1L:
Transcription elongation regulator 1-like Hs.126575 [show with all ESTs ] Unigene Representative Sequence: AK096269 2 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000483040 (uc009yax.1 ) ENST00000368642 (uc001lkp.3 ) Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for TCERG1L (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for TCERG1L (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: TCERG1L (NM_174937 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TCERG1L Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat TCERG1L
Additional cDNA sequence: AK096269.1 BC042951.1 BC093639.1 BC101535.1
3 DOTS entries : DT.107267 DT.99935702
DT.121293022 18 AceView cDNA sequences :
BM689725 T19376 AA973690 BM706684 AA829921 AI733278 NM_174937 AW138994 AK096269 BU069015 AI791230 AI732913 BC042951 T19377 AI793303 BM711707 BI550916 BI004698 GeneLoc Exon Structure 2 Alternative Splicing Database (ASD) splice patterns (SP) for TCERG1L About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 SP1 :             -     -   -               SP2 :                                
ECgene alternative splicing isoforms for TCERG1L
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Expression for TCERG1L gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section TCERG1L expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: --
About this image TCERG1L expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table See TCERG1L Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TCERG1L SOURCE GeneReport for Unigene cluster: Hs.126575 SABiosciences Custom PCR Arrays for TCERG1L Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for TCERG1LBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat TCERG1L QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat TCERG1L QIAGEN QuantiFast Probe-based Assays in human , mouse , rat TCERG1L In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCERG1L
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Orthologsfor TCERG1L gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of eukaryotes.
Orthologs for TCERG1L gene from 7/24 species (see all 24 ) About this table
ENSEMBL Gene Tree for TCERG1L (if available)TreeFam Gene Tree for TCERG1L (if available)
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Paralogsfor TCERG1L gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for TCERG1L gene PRPF40B 2 PRPF40A 2 TCERG1 2 1 SIMAP similar gene for TCERG1L using alignment to 1 protein entry: TCRGL_HUMAN :TCERG1
TCERG1L for paralogs About GeneDecksing 1 Pseudogenes.org Pseudogene for TCERG1L PGOHUM00000236258
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Genomic Variantsfor TCERG1L gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 10 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for TCERG1L (132890654 - 133109984 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 18 variations for TCERG1L 12 CNVs : 34863 23381 61078 43550 85531 71153 58427 65818 85530 85529 71154 6851 6 Indels : 71155 75431 101083 24380 85532 11515
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing TCERG1L
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Disorders
/ Diseasesfor TCERG1L gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
TCERG1L for disorders About GeneDecksing 2 diseases for TCERG1L : About MalaCards alzheimer's disease malaria Human Genome Epidemiology (HuGE) Navigator: TCERG1L (4 documents) Export disorders for TCERG1L gene to outside databases
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Publicationsfor TCERG1L gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for TCERG1L gene, integrated from 9 sources (see all 13 ): (articles sorted by number of sources associating them with TCERG1L) Utopia : connect your pdf to the dynamic world of online information
A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales. (PubMed id 22832960) 1 Service S.K....Freimer N.B. (2012) A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. (PubMed id 22412388) 1 Kenny E.E....Peter I. (2012) Genome-wide association study identifies novel loci as sociation with fasting insulin and insulin resistance in African Americans. (PubMed id 22791750) 1 Chen G....Rotimi C. (2012) Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. (PubMed id 21490949) 1 Sim X....Tai E.S. (2011) Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614) 1 Rose J.E....Uhl G.R. (2010) Case-control genome-wide association study of attenti on-deficit/hyperactivity disorder. (PubMed id 20732627) 1 Neale B.M....Biederman J. (2010) The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974) 2 Sjoeblom T.... Velculescu V.E. (2006) A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451) 1 Grupe A....Goate A. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 Ota T.... Sugano S. (2004)
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External Searches for TCERG1L gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing TCERG1L gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing TCERG1L gene
(According to HUGE )
About This Section --
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Specialized Databases showing TCERG1L gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for TCERG1L Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for TCERG1L gene: Search GeneIP for patents involving TCERG1L GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TCERG1L gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for TCERG1L OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for TCERG1L OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for TCERG1L OriGene Protein Over-expression Lysate for TCERG1L Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for TCERG1L Browse 3'-UTR reporter clones for miRNA target validation OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for TCERG1L OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for TCERG1L Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for TCERG1L OriGene Custom Protein Services for TCERG1L OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TCERG1L QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing TCERG1L QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCERG1L QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat TCERG1L QIAGEN QuantiFast Probe-based Assays in human , mouse , rat TCERG1L QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat TCERG1L
Search Tocris compounds for TCERG1L
TCERG1L Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCERG1L
Search ThermoFisher Antibodies for TCERG1L
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat TCERG1L
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Aliases for TCERG1L
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