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Aliases for TCERG1L Gene

Aliases for TCERG1L Gene

  • Transcription Elongation Regulator 1 Like 2 3 5
  • Transcription Elongation Regulator 1-Like Protein 3
  • Transcription Elongation Regulator 1-Like 2
  • 5730476P14Rik 3

External Ids for TCERG1L Gene

Previous GeneCards Identifiers for TCERG1L Gene

  • GC10M132365
  • GC10M132780
  • GC10M132890
  • GC10M126465

Summaries for TCERG1L Gene

GeneCards Summary for TCERG1L Gene

TCERG1L (Transcription Elongation Regulator 1 Like) is a Protein Coding gene. An important paralog of this gene is TCERG1.

Additional gene information for TCERG1L Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCERG1L Gene

Genomics for TCERG1L Gene

GeneHancer (GH) Regulatory Elements for TCERG1L Gene

Promoters and enhancers for TCERG1L Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH10I131310 Promoter/Enhancer 1.2 EPDnew Ensembl ENCODE 598.5 -0.1 -54 2.5 CTCF ZNF143 BACH1 SIN3A REST ZFX EZH2 TCERG1L LOC101927461
GH10I131093 Enhancer 0.8 Ensembl ENCODE 0.1 +217.2 217214 2.2 ZBTB21 ZNF398 NR2F2 GABPA ZNF512B ZNF366 ZBTB48 ZNF341 TCERG1L-AS1 PIR59984 TCERG1L
GH10I131127 Enhancer 0.3 ENCODE 0.1 +184.5 184523 0.9 NCOA3 GC10P131105 LOC105378563 TCERG1L
GH10I131131 Enhancer 0.2 ENCODE 0.1 +179.2 179235 1.4 TCERG1L-AS1 GC10P131105 LOC105378563 TCERG1L
GH10I131126 Enhancer 0.2 ENCODE 0.1 +185.1 185128 0.2 GC10P131105 LOC105378563 TCERG1L
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TCERG1L on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TCERG1L gene promoter:

Genomic Locations for TCERG1L Gene

Genomic Locations for TCERG1L Gene
219,331 bases
Minus strand

Genomic View for TCERG1L Gene

Genes around TCERG1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TCERG1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TCERG1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCERG1L Gene

Proteins for TCERG1L Gene

  • Protein details for TCERG1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transcription elongation regulator 1-like protein
    Protein Accession:
    Secondary Accessions:
    • Q5VWI2
    • Q86XM8

    Protein attributes for TCERG1L Gene

    586 amino acids
    Molecular mass:
    65660 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH42951.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH93639.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI01536.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for TCERG1L Gene

Post-translational modifications for TCERG1L Gene

No Post-translational modifications

Other Protein References for TCERG1L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TCERG1L Gene

Domains & Families for TCERG1L Gene

Gene Families for TCERG1L Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for TCERG1L Gene

Suggested Antigen Peptide Sequences for TCERG1L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TCERG1L: view

No data available for UniProtKB/Swiss-Prot for TCERG1L Gene

Function for TCERG1L Gene

Phenotypes From GWAS Catalog for TCERG1L Gene

genes like me logo Genes that share phenotypes with TCERG1L: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TCERG1L Gene

Localization for TCERG1L Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TCERG1L gene
Compartment Confidence
nucleus 3
cytosol 2
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TCERG1L Gene

Pathways & Interactions for TCERG1L Gene

SuperPathways for TCERG1L Gene

No Data Available

Interacting Proteins for TCERG1L Gene

STRING Interaction Network Preview (showing 5 interactants - click image to see 10)
Selected Interacting proteins: Q5VWI1-TCRGL_HUMAN ENSP00000357631 for TCERG1L Gene via IID STRING

Gene Ontology (GO) - Biological Process for TCERG1L Gene


No data available for Pathways by source and SIGNOR curated interactions for TCERG1L Gene

Drugs & Compounds for TCERG1L Gene

No Compound Related Data Available

Transcripts for TCERG1L Gene

mRNA/cDNA for TCERG1L Gene

(3) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(18) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TCERG1L Gene

Transcription elongation regulator 1-like:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TCERG1L Gene

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15
SP1: - - -

Relevant External Links for TCERG1L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TCERG1L Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TCERG1L Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TCERG1L Gene

This gene is overexpressed in Thyroid (x10.6), Brain - Cortex (x6.9), Brain - Frontal Cortex (BA9) (x6.8), and Brain - Anterior cingulate cortex (BA24) (x6.5).

Protein differential expression in normal tissues from HIPED for TCERG1L Gene

This gene is overexpressed in Breast (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TCERG1L Gene

Protein tissue co-expression partners for TCERG1L Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TCERG1L Gene:


SOURCE GeneReport for Unigene cluster for TCERG1L Gene:

genes like me logo Genes that share expression patterns with TCERG1L: view

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TCERG1L Gene

Orthologs for TCERG1L Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TCERG1L Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TCERG1L 33 34
  • 98.63 (n)
(Canis familiaris)
Mammalia TCERG1L 33 34
  • 83.72 (n)
(Rattus norvegicus)
Mammalia Tcerg1l 33
  • 82.02 (n)
(Mus musculus)
Mammalia Tcerg1l 33 16 34
  • 81.41 (n)
(Ornithorhynchus anatinus)
Mammalia TCERG1L 34
  • 80 (a)
(Bos Taurus)
Mammalia LOC101906614 33
  • 70.83 (n)
(Monodelphis domestica)
Mammalia TCERG1L 34
  • 64 (a)
(Gallus gallus)
Aves TCERG1L 34 33
  • 71.53 (n)
(Anolis carolinensis)
Reptilia TCERG1L 34
  • 60 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia tcerg1l 33
  • 64.49 (n)
(Danio rerio)
Actinopterygii TCERG1L 34
  • 63 (a)
LOC101886358 33
  • 62.19 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG42724 34
  • 13 (a)
(Caenorhabditis elegans)
Secernentea tcer-1 34
  • 14 (a)
ZK1127.6 34
  • 9 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes PRP40 34
  • 8 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.8543 34
  • 21 (a)
Species where no ortholog for TCERG1L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TCERG1L Gene

Gene Tree for TCERG1L (if available)
Gene Tree for TCERG1L (if available)

Paralogs for TCERG1L Gene

Paralogs for TCERG1L Gene

(1) SIMAP similar genes for TCERG1L Gene using alignment to 1 proteins: Pseudogenes for TCERG1L Gene

genes like me logo Genes that share paralogs with TCERG1L: view

Variants for TCERG1L Gene

Sequence variations from dbSNP and Humsavar for TCERG1L Gene

SNP ID Clin Chr 10 pos Variation AA Info Type
VAR_037602 A colorectal cancer sample p.Lys437Thr
rs1000001405 -- 131,194,871(-) G/C genic_downstream_transcript_variant, intron_variant
rs1000043340 -- 131,155,454(-) C/T genic_downstream_transcript_variant, intron_variant
rs1000044777 -- 131,175,878(-) G/T genic_downstream_transcript_variant, intron_variant
rs1000047657 -- 131,169,713(-) T/G genic_downstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for TCERG1L Gene

Variant ID Type Subtype PubMed ID
dgv1442n54 CNV loss 21841781
dgv1443n54 CNV loss 21841781
dgv1444n54 CNV loss 21841781
dgv1445n54 CNV loss 21841781
dgv1446n54 CNV loss 21841781
dgv1447n54 CNV gain 21841781
dgv1448n54 CNV loss 21841781
dgv1449n54 CNV loss 21841781
dgv175e199 CNV deletion 23128226
dgv176e199 CNV deletion 23128226
dgv182n67 CNV loss 20364138
dgv28n73 CNV deletion 24416366
dgv303e212 CNV loss 25503493
dgv546n106 CNV deletion 24896259
dgv547n106 CNV deletion 24896259
esv1008219 CNV deletion 20482838
esv1161251 CNV insertion 17803354
esv1452199 CNV deletion 17803354
esv1596333 CNV insertion 17803354
esv23166 CNV loss 19812545
esv2580680 CNV insertion 19546169
esv26490 CNV loss 19812545
esv2664001 CNV deletion 23128226
esv2677389 CNV deletion 23128226
esv2743526 CNV deletion 23290073
esv2743527 CNV deletion 23290073
esv2743528 CNV deletion 23290073
esv2743529 CNV deletion 23290073
esv2743531 CNV deletion 23290073
esv2743532 CNV deletion 23290073
esv2743533 CNV deletion 23290073
esv2743534 CNV deletion 23290073
esv2743535 CNV deletion 23290073
esv2743536 CNV deletion 23290073
esv2743537 CNV deletion 23290073
esv2760145 CNV loss 21179565
esv27895 CNV gain 19812545
esv28224 CNV loss 19812545
esv3237 CNV loss 18987735
esv32814 CNV gain+loss 17666407
esv3346144 CNV insertion 20981092
esv3547075 CNV deletion 23714750
esv3547076 CNV deletion 23714750
esv3579231 CNV loss 25503493
esv3579235 CNV loss 25503493
esv3624951 CNV loss 21293372
esv3624952 CNV gain 21293372
esv3624953 CNV loss 21293372
esv3624954 CNV loss 21293372
esv3624956 CNV gain 21293372
esv3624957 CNV loss 21293372
esv3891898 CNV loss 25118596
esv6315 CNV loss 19470904
nsv1042634 CNV loss 25217958
nsv1048253 CNV gain 25217958
nsv1051892 CNV loss 25217958
nsv1054934 CNV gain 25217958
nsv1069975 CNV deletion 25765185
nsv1070904 CNV deletion 25765185
nsv1122571 CNV deletion 24896259
nsv1124493 CNV deletion 24896259
nsv1125516 CNV tandem duplication 24896259
nsv1126273 CNV deletion 24896259
nsv1128533 CNV deletion 24896259
nsv1133160 CNV tandem duplication 24896259
nsv1134946 CNV deletion 24896259
nsv1139392 CNV deletion 24896259
nsv25335 CNV deletion 16902084
nsv428242 CNV gain 18775914
nsv470974 CNV gain 18288195
nsv498745 CNV loss 21111241
nsv509375 CNV insertion 20534489
nsv511463 CNV loss 21212237
nsv512193 CNV loss 21212237
nsv552420 CNV gain+loss 21841781
nsv552442 CNV loss 21841781
nsv552443 CNV gain 21841781
nsv552444 CNV loss 21841781
nsv552448 CNV loss 21841781
nsv552449 CNV gain+loss 21841781
nsv552461 CNV gain+loss 21841781
nsv552462 CNV loss 21841781
nsv552463 CNV loss 21841781
nsv7621 CNV deletion 18451855
nsv7622 CNV insertion 18451855
nsv820144 CNV loss 19587683
nsv825646 CNV loss 20364138
nsv825647 CNV loss 20364138
nsv825648 CNV gain 20364138
nsv825649 CNV gain 20364138
nsv832027 CNV gain 17160897
nsv832028 CNV loss 17160897
nsv948230 CNV duplication 23825009

Variation tolerance for TCERG1L Gene

Residual Variation Intolerance Score: 85.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.26; 52.84% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TCERG1L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TCERG1L Gene

Disorders for TCERG1L Gene

Additional Disease Information for TCERG1L

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for TCERG1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TCERG1L Gene

Publications for TCERG1L Gene

  1. A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. (PMID: 22412388) Kenny EE … Peter I (PLoS genetics 2012) 3 44 58
  2. Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. (PMID: 21490949) Sim X … Tai ES (PLoS genetics 2011) 3 44 58
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
  4. Case-control genome-wide association study of attention-deficit/hyperactivity disorder. (PMID: 20732627) Neale BM … IMAGE II Consortium Group (Journal of the American Academy of Child and Adolescent Psychiatry 2010) 3 44 58
  5. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A … Goate A (American journal of human genetics 2006) 3 44 58

Products for TCERG1L Gene

Sources for TCERG1L Gene

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