Aliases for TCERG1 Gene
External Ids for TCERG1 Gene
Previous HGNC Symbols for TCERG1 Gene
Previous GeneCards Identifiers for TCERG1 Gene
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. [provided by RefSeq, Jul 2008]
GeneCards Summary for TCERG1 Gene
TCERG1 (Transcription Elongation Regulator 1) is a Protein Coding gene. Among its related pathways are Spliceosome. GO annotations related to this gene include transcription coactivator activity and RNA polymerase II transcription corepressor activity. An important paralog of this gene is PRPF40A.
UniProtKB/Swiss-Prot for TCERG1 Gene
Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.