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Aliases for TCEANC2 Gene

Aliases for TCEANC2 Gene

  • Transcription Elongation Factor A N-Terminal And Central Domain Containing 2 2 3
  • Transcription Elongation Factor A (SII) N-Terminal And Central Domain Containing 2 2 3 5
  • C1orf83 3 4
  • Chromosome 1 Open Reading Frame 83 2

External Ids for TCEANC2 Gene

Previous HGNC Symbols for TCEANC2 Gene

  • C1orf83

Previous GeneCards Identifiers for TCEANC2 Gene

  • GC01P054520

Summaries for TCEANC2 Gene

GeneCards Summary for TCEANC2 Gene

TCEANC2 (Transcription Elongation Factor A N-Terminal And Central Domain Containing 2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCEANC2 Gene

Genomics for TCEANC2 Gene

Regulatory Elements for TCEANC2 Gene

Promoters for TCEANC2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TCEANC2 on UCSC Golden Path with GeneCards custom track

Genomic Location for TCEANC2 Gene

Chromosome:
1
Start:
54,053,572 bp from pter
End:
54,112,519 bp from pter
Size:
58,948 bases
Orientation:
Plus strand

Genomic View for TCEANC2 Gene

Genes around TCEANC2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TCEANC2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TCEANC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCEANC2 Gene

Proteins for TCEANC2 Gene

  • Protein details for TCEANC2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96MN5-TEAN2_HUMAN
    Recommended name:
    Transcription elongation factor A N-terminal and central domain-containing protein 2
    Protein Accession:
    Q96MN5
    Secondary Accessions:
    • Q5T702
    • Q8N8N2

    Protein attributes for TCEANC2 Gene

    Size:
    208 amino acids
    Molecular mass:
    24150 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI22668.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for TCEANC2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TCEANC2 Gene

Proteomics data for TCEANC2 Gene at MOPED

Post-translational modifications for TCEANC2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TCEANC2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TCEANC2 Gene

Domains & Families for TCEANC2 Gene

Protein Domains for TCEANC2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TCEANC2 Gene

Graphical View of Domain Structure for InterPro Entry

Q96MN5

UniProtKB/Swiss-Prot:

TEAN2_HUMAN :
  • Contains 1 TFIIS central domain.
  • Belongs to the TCEANC2 family.
Domain:
  • Contains 1 TFIIS central domain.
  • Contains 1 TFIIS N-terminal domain.
Family:
  • Belongs to the TCEANC2 family.
genes like me logo Genes that share domains with TCEANC2: view

No data available for Gene Families for TCEANC2 Gene

Function for TCEANC2 Gene

genes like me logo Genes that share phenotypes with TCEANC2: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TCEANC2 Gene

Localization for TCEANC2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TCEANC2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TCEANC2 Gene COMPARTMENTS Subcellular localization image for TCEANC2 gene
Compartment Confidence
nucleus 5
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for TCEANC2 Gene

Pathways & Interactions for TCEANC2 Gene

SuperPathways for TCEANC2 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TCEANC2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TCEANC2 Gene

Drugs & Compounds for TCEANC2 Gene

No Compound Related Data Available

Transcripts for TCEANC2 Gene

Unigene Clusters for TCEANC2 Gene

Transcription elongation factor A (SII) N-terminal and central domain containing 2:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TCEANC2 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b
SP1: - -
SP2: - - -
SP3: -
SP4:

Relevant External Links for TCEANC2 Gene

GeneLoc Exon Structure for
TCEANC2
ECgene alternative splicing isoforms for
TCEANC2

Expression for TCEANC2 Gene

mRNA expression in normal human tissues for TCEANC2 Gene

Protein differential expression in normal tissues from HIPED for TCEANC2 Gene

This gene is overexpressed in Lung (64.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TCEANC2 Gene



SOURCE GeneReport for Unigene cluster for TCEANC2 Gene Hs.558618

genes like me logo Genes that share expression patterns with TCEANC2: view

Protein tissue co-expression partners for TCEANC2 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TCEANC2 Gene

Orthologs for TCEANC2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TCEANC2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TCEANC2 35
  • 99.68 (n)
  • 99.52 (a)
TCEANC2 36
  • 87 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TCEANC2 36
  • 90 (a)
OneToOne
TCEANC2 35
  • 93.11 (n)
  • 91.35 (a)
dog
(Canis familiaris)
Mammalia TCEANC2 35
  • 92.95 (n)
  • 90.38 (a)
TCEANC2 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tceanc2 16
Tceanc2 36
  • 91 (a)
OneToOne
Tceanc2 35
  • 88.89 (n)
  • 91.3 (a)
oppossum
(Monodelphis domestica)
Mammalia TCEANC2 36
  • 83 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TCEANC2 36
  • 63 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tceanc2 35
  • 86.47 (n)
  • 88.41 (a)
chicken
(Gallus gallus)
Aves TCEANC2 36
  • 69 (a)
OneToOne
TCEANC2 35
  • 70.67 (n)
  • 69.23 (a)
lizard
(Anolis carolinensis)
Reptilia TCEANC2 36
  • 72 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.5187 35
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.17785 35
zebrafish
(Danio rerio)
Actinopterygii tceanc2 36
  • 65 (a)
OneToOne
tceanc2 35
  • 63.93 (n)
  • 66.18 (a)
Species with no ortholog for TCEANC2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TCEANC2 Gene

ENSEMBL:
Gene Tree for TCEANC2 (if available)
TreeFam:
Gene Tree for TCEANC2 (if available)

Paralogs for TCEANC2 Gene

No data available for Paralogs for TCEANC2 Gene

Variants for TCEANC2 Gene

Sequence variations from dbSNP and Humsavar for TCEANC2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1015981 -- 54,077,649(-) cctag(C/T)AAATA intron-variant
rs1181087 -- 54,061,226(+) AGTGA(A/C)TTCCA intron-variant
rs1411171 -- 54,112,831(+) TCACC(A/C)TGCCT downstream-variant-500B
rs3820112 -- 54,056,634(-) GAATA(C/T)GGGTG intron-variant
rs3086146 -- 54,077,000(-) CACCT(-/CCT)TCAAG intron-variant

Variation tolerance for TCEANC2 Gene

Residual Variation Intolerance Score: 47.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.24; 24.76% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TCEANC2 Gene

HapMap Linkage Disequilibrium report
TCEANC2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TCEANC2 Gene

Disorders for TCEANC2 Gene

Relevant External Links for TCEANC2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TCEANC2

No disorders were found for TCEANC2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TCEANC2 Gene

Publications for TCEANC2 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3

Products for TCEANC2 Gene

Sources for TCEANC2 Gene

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