TCEANC2 Gene
protein-coding GIFtS: 38
GCID: GC01P054520
|
|
transcription elongation factor A (SII) N-terminal and central...(Previous name: chromosome 1 open reading frame 83 )
(Previous symbol: C1orf83)
| |
Aliases
for TCEANC2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Transcription Elongation Factor A (SII) N-Terminal And Central DomainContaining 21 2 | | C1orf831 2 3 | | FLJ321121 | | Chromosome 1 Open Reading Frame 831 | | RP4-758J24.32 | | Transcription Elongation Factor A N-Terminal And Central Domain-ContainingProtein 22 |
Export aliases for TCEANC2 gene to outside databases |
Summaries
for TCEANC2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TCEANC2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for TCEANC2
Other transcription factors
Search SABiosciences Chromatin IP Primers for TCEANC2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCEANC2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p32.3 Ensembl cytogenetic band: 1p32.3 HGNC cytogenetic band: 1p32.3TCEANC2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P054520: view genomic region
(about GC identifiers)
Start:
|
54,519,260 bp from pter |
End:
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54,578,192 bp from pter |
Size:
|
58,933 bases |
Orientation:
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plus strand |
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Proteins
for TCEANC2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TEAN2_HUMAN, Q96MN5 (See
protein sequence)Recommended Name: Transcription elongation factor A N-terminal and central domain-containing protein 2 Size: 208 amino acids; 24150 Da
Subcellular location: Nucleus (By similarity)
Sequence caution: Sequence=CAI22668.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q5T702 Q8N8N2Alternative splicing: 2 isoforms: Q96MN5-1 Q96MN5-2 Explore the universe of human proteins at neXtProt for TCEANC2: NX_Q96MN5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96MN5
TCEANC2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_694580.1
ENSEMBL proteins: ENSP00000234827 ENSP00000360382
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
TCEANC2 for ontologies About GeneDecksing
TCEANC2 Antibody Products:
Assay Products for TCEANC2: |
Protein
Domains /
Families
for TCEANC2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TCEANC2 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96MN5ProtoNet protein and cluster: Q96MN5 UniProtKB/Swiss-Prot: TEAN2_HUMAN, Q96MN5Similarity: Belongs to the TCEANC2 familySimilarity: Contains 1 TFIIS central domainSimilarity: Contains 1 TFIIS N-terminal domain |
Function
for TCEANC2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TCEANC2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TCEANC2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
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Synthesis Service for TCEANC2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCEANC2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCEANC2 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003677 | DNA binding |
IEA | -- |
TCEANC2 for ontologies About GeneDecksing
|
Pathways & Interactions
for TCEANC2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TCEANC2
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- |
TCEANC2 for ontologies About GeneDecksing
|
Drugs & Compounds
for TCEANC2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TCEANC2
Search CenterWatch for drugs/clinical trials and news about TCEANC2 / TEAN2
|
Transcripts
for TCEANC2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TCEANC2 gene: NM_153035.1 Unigene Cluster for TCEANC2: Transcription elongation factor A (SII) N-terminal and central domain containing 2 Hs.558618 [show with all ESTs]Unigene Representative Sequence: AK0566743 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000498272(uc001cwu.1) ENST00000234827(uc001cwt.1) ENST00000371331
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TCEANC2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TCEANC2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TCEANC2 (NM_153035) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TCEANC2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCEANC2 |
Additional cDNA sequence: AK027328.1 AK056674.1 AK096488.1 AL049253.1 BC035374.1 9 DOTS entries: DT.100840671 DT.99953506 DT.40256276 DT.40267098 DT.121431039 DT.40234713 DT.40248675 DT.92051776 DT.97857962 24/56 AceView cDNA sequences (see all 56): BC035374 BM675385 BM548881 CR592771 NM_153035 BP430743 BX097476 AL049253 CB047610 BE858049 AK096488 BM714872 BQ082987 AV728976 BM768878 AK056674 BU941766 AL555802 BI909833 AA495777 BX489416 CB146767 BU739633 BX443734
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for TCEANC2 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b |
|---|
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| SP1: | | | | | - | | | | - | | | | | | | | | | | | |
| SP2: | | | | | - | | | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for TCEANC2
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Expression
for TCEANC2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TCEANC2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGAGGCTAC
About this image
See TCEANC2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TCEANC2
SOURCE GeneReport for Unigene cluster: Hs.558618
SABiosciences Custom PCR Arrays for TCEANC2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TCEANC2
Browse OriGene validated miRNA SYBR primer pairs
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Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCEANC2 |
Orthologs
for TCEANC2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TCEANC2 gene from 5/14 species (see all 14) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Tceanc25
Tdeanc21 |
RIKEN cDNA 2210012G02 gene5
transcription elongation factor A (SII) N-terminal more1 |
88.89(n)1
91.3(a)1 |
|
4 (50.07 cM)5
665261 NM_025617.21 NP_079893.11
1071341555 |
chicken
(Gallus gallus) |
Aves |
TCEANC21 |
transcription elongation factor A (SII) N-terminal more |
70.67(n)
69.23(a) |
|
424657 NM_001195594.1 NP_001182523.1 |
lizard
(Anolis carolinensis) |
Reptilia |
TCEANC26 |
-- |
72(a) |
1 ↔ 1 |
4(105109304-105120665) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.51872 |
Xenopus laevis transcribed sequence with weak similarity more |
73.81(n) |
|
BX855571.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
tceanc21 |
transcription elongation factor A (SII) N-terminal more |
63.93(n)
66.18(a) |
|
567698 XM_690995.3 XP_696087.1 |
ENSEMBL Gene Tree for TCEANC2 (if available)
TreeFam Gene Tree for TCEANC2 (if available) |
Paralogs
for TCEANC2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TCEANC2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TCEANC2 (54519260 - 54578192 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TCEANC2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TCEANC2 |
|
Disorders
/ Diseases
for TCEANC2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for TCEANC2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TCEANC2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TCEANC2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
|
External Searches for TCEANC2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TCEANC2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TCEANC2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TCEANC2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TCEANC2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TCEANC2 gene:
Search GeneIP for patents involving TCEANC2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TCEANC2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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variant library, vector shuttling | | | OriGene Custom Antibody Services for TCEANC2 | | OriGene Custom Protein Services for TCEANC2 | | | OriGene Custom Immunoassay Development | | |
| |
 |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TCEANC2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TCEANC2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCEANC2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TCEANC2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TCEANC2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TCEANC2 |
| |
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| | | | Search Tocris compounds for TCEANC2 |
| |  |  |  |  | | | | |
 |
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 |
 | | | TCEANC2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCEANC2 |
|  |  |  | | | | Search ThermoFisher Antibodies for TCEANC2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCEANC2 |
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