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Aliases for TCEANC Gene

Aliases for TCEANC Gene

  • Transcription Elongation Factor A N-Terminal And Central Domain Containing 2 3 5
  • Transcription Elongation Factor A (SII) N-Terminal And Central Domain Containing 2
  • TFIIS Central Domain-Containing Protein 1 4

External Ids for TCEANC Gene

Previous GeneCards Identifiers for TCEANC Gene

  • GC0XP013582
  • GC0XP013584
  • GC0XP011429

Summaries for TCEANC Gene

GeneCards Summary for TCEANC Gene

TCEANC (Transcription Elongation Factor A N-Terminal And Central Domain Containing) is a Protein Coding gene. An important paralog of this gene is TCEA2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCEANC Gene

Genomics for TCEANC Gene

Regulatory Elements for TCEANC Gene

Enhancers for TCEANC Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF013647 1.3 FANTOM5 Ensembl ENCODE 19.4 -4.7 -4727 1.8 PKNOX1 ATF1 ARNT CREB3L1 ELK1 GATA2 FOS JUNB NCOA1 TSHZ1 TCEANC RAB9A RN7SKP20
GH0XF013649 0.4 ENCODE 18.6 -2.5 -2496 1.8 ATF1 FEZF1 ZIC2 GLIS2 ZNF766 SCRT2 PRDM10 FOSL2 KLF8 ZNF639 TCEANC RAB9A RN7SKP20
GH0XF013658 1 FANTOM5 Ensembl ENCODE 17.3 +6.5 6465 1.8 TBP CTCF CEBPG RAD21 RFX5 SMC3 RCOR1 ZNF652 ZHX1 CHD2 TCEANC RAB9A
GH0XF013651 0.2 ENCODE 17.1 +0.4 426 3.6 HDGF PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF766 TCEANC ATXN3L ENSG00000235592 GS1-600G8.3 RAB9A
GH0XF013661 0.5 Ensembl ENCODE 16.6 +11.2 11212 4.2 BCOR PKNOX1 ZNF146 RFX5 GTF3C2 ZNF316 GATA3 ZFHX2 MAFK NFE2L2 TCEANC ENSG00000235592 ATXN3L GS1-600G8.3 RAB9A
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TCEANC on UCSC Golden Path with GeneCards custom track

Promoters for TCEANC Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000070684 554 2001 HDGF PKNOX1 CREB3L1 ARID4B SIN3A FEZF1 DMAP1 YY1 ZNF143 FOS

Genomic Location for TCEANC Gene

Chromosome:
X
Start:
13,652,646 bp from pter
End:
13,681,964 bp from pter
Size:
29,319 bases
Orientation:
Plus strand

Genomic View for TCEANC Gene

Genes around TCEANC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TCEANC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TCEANC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCEANC Gene

Proteins for TCEANC Gene

  • Protein details for TCEANC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8B7-TEANC_HUMAN
    Recommended name:
    Transcription elongation factor A N-terminal and central domain-containing protein
    Protein Accession:
    Q8N8B7
    Secondary Accessions:
    • A6NI06
    • B2RDM3

    Protein attributes for TCEANC Gene

    Size:
    351 amino acids
    Molecular mass:
    40245 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04930.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for TCEANC Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TCEANC Gene

Post-translational modifications for TCEANC Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TCEANC Gene

Domains & Families for TCEANC Gene

Protein Domains for TCEANC Gene

Suggested Antigen Peptide Sequences for TCEANC Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N8B7

UniProtKB/Swiss-Prot:

TEANC_HUMAN :
  • Contains 1 TFIIS central domain.
Domain:
  • Contains 1 TFIIS central domain.
  • Contains 1 TFIIS N-terminal domain.
genes like me logo Genes that share domains with TCEANC: view

No data available for Gene Families for TCEANC Gene

Function for TCEANC Gene

Gene Ontology (GO) - Molecular Function for TCEANC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TCEANC: view

Phenotypes for TCEANC Gene

genes like me logo Genes that share phenotypes with TCEANC: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TCEANC Gene

Localization for TCEANC Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TCEANC Gene COMPARTMENTS Subcellular localization image for TCEANC gene
Compartment Confidence
nucleus 5
mitochondrion 3
cytosol 2
peroxisome 2

Gene Ontology (GO) - Cellular Components for TCEANC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with TCEANC: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TCEANC Gene

Pathways & Interactions for TCEANC Gene

SuperPathways for TCEANC Gene

No Data Available

Gene Ontology (GO) - Biological Process for TCEANC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006357 regulation of transcription from RNA polymerase II promoter IEA --
GO:0032784 regulation of DNA-templated transcription, elongation IEA --
genes like me logo Genes that share ontologies with TCEANC: view

No data available for Pathways by source and SIGNOR curated interactions for TCEANC Gene

Transcripts for TCEANC Gene

Unigene Clusters for TCEANC Gene

Transcription elongation factor A (SII) N-terminal and central domain containing:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TCEANC Gene

No ASD Table

Relevant External Links for TCEANC Gene

GeneLoc Exon Structure for
TCEANC
ECgene alternative splicing isoforms for
TCEANC

Expression for TCEANC Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TCEANC Gene

NURSA nuclear receptor signaling pathways regulating expression of TCEANC Gene:

TCEANC

SOURCE GeneReport for Unigene cluster for TCEANC Gene:

Hs.222855
genes like me logo Genes that share expression patterns with TCEANC: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TCEANC Gene

Orthologs for TCEANC Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TCEANC Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TCEANC 34 35
  • 99.39 (n)
dog
(Canis familiaris)
Mammalia TCEANC 34 35
  • 84.3 (n)
rat
(Rattus norvegicus)
Mammalia Tceanc 34
  • 80.27 (n)
mouse
(Mus musculus)
Mammalia Tceanc 34 16 35
  • 79.75 (n)
cow
(Bos Taurus)
Mammalia TCEANC 34
  • 75.58 (n)
-- 35
  • 65 (a)
OneToMany
-- 35
  • 63 (a)
OneToMany
chicken
(Gallus gallus)
Aves TCEANC 34 35
  • 62.74 (n)
lizard
(Anolis carolinensis)
Reptilia TCEANC 35
  • 42 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tceanc 34
  • 58.15 (n)
Str.12985 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.17490 34
zebrafish
(Danio rerio)
Actinopterygii LOC100150588 34
  • 52.99 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG8117 35
  • 38 (a)
ManyToMany
TfIIS 35
  • 27 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea T24H10.1 35
  • 24 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes DST1 35
  • 19 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2769 35
  • 24 (a)
OneToMany
Species where no ortholog for TCEANC was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TCEANC Gene

ENSEMBL:
Gene Tree for TCEANC (if available)
TreeFam:
Gene Tree for TCEANC (if available)

Paralogs for TCEANC Gene

Paralogs for TCEANC Gene

(3) SIMAP similar genes for TCEANC Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TCEANC: view

Variants for TCEANC Gene

Sequence variations from dbSNP and Humsavar for TCEANC Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs10667209 -- 13,658,576(+) AGATA(-/TACATA)CTGAA intron-variant
rs111409484 -- 13,660,356(+) TATAA(C/T)CCATC intron-variant
rs112728735 -- 13,657,857(+) TTCAT(-/AGC)AGTAT intron-variant
rs112768800 -- 13,665,637(+) AGGCC(A/G)GAGAA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs112828240 -- 13,651,719(+) ACCCC(C/G)CTACC upstream-variant-2KB

Variation tolerance for TCEANC Gene

Residual Variation Intolerance Score: 54.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.96; 36.35% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TCEANC Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TCEANC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TCEANC Gene

Disorders for TCEANC Gene

Relevant External Links for TCEANC

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TCEANC

No disorders were found for TCEANC Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TCEANC Gene

Publications for TCEANC Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage. (PMID: 25184681) Hill S.J. … Livingston D.M. (Genes Dev. 2014) 3 64
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64

Products for TCEANC Gene

Sources for TCEANC Gene

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