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Aliases for TCEANC Gene

Aliases for TCEANC Gene

  • Transcription Elongation Factor A N-Terminal And Central Domain Containing 2 3 5
  • Transcription Elongation Factor A (SII) N-Terminal And Central Domain Containing 2
  • TFIIS Central Domain-Containing Protein 1 4

External Ids for TCEANC Gene

Previous GeneCards Identifiers for TCEANC Gene

  • GC0XP013582
  • GC0XP013584
  • GC0XP011429

Summaries for TCEANC Gene

GeneCards Summary for TCEANC Gene

TCEANC (Transcription Elongation Factor A N-Terminal And Central Domain Containing) is a Protein Coding gene. An important paralog of this gene is TCEA3.

Additional gene information for TCEANC Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCEANC Gene

Genomics for TCEANC Gene

GeneHancer (GH) Regulatory Elements for TCEANC Gene

Promoters and enhancers for TCEANC Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI013651 Promoter/Enhancer 1.5 Ensembl ENCODE 567.1 +0.4 426 3.6 HDGF PKNOX1 CLOCK ARID4B SIN3A FEZF1 DMAP1 YY1 POLR2B ZNF143 TCEANC RAB9A
GH0XI013655 Promoter 0.5 EPDnew 550.8 +2.7 2710 0.1 TCEANC RAB9A
GH0XI013647 Enhancer 1.5 FANTOM5 Ensembl ENCODE 19.4 -4.7 -4726 1.8 PKNOX1 SMAD1 FOXA2 ARNT POLR2B ZNF766 FOS ZNF662 ZNF592 MEF2D GEMIN8 TCEANC RAB9A RN7SKP20
GH0XI013687 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE 10.9 +39.0 38951 7.2 PKNOX1 ARNT SIN3A DMAP1 ZNF2 YY1 POLR2B SP3 SMARCB1 KAT8 RAB9A OFD1 TCEANC TRAPPC2 ATXN3L
GH0XI013667 Enhancer 1.5 FANTOM5 Ensembl ENCODE 15.5 +16.5 16515 2.9 HDGF PKNOX1 SMAD1 ARNT FEZF1 IRF4 YY1 ZNF213 ZNF143 ZNF207 TCEANC RAB9A
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TCEANC on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the TCEANC gene promoter:

Genomic Locations for TCEANC Gene

Genomic Locations for TCEANC Gene
chrX:13,652,646-13,681,964
(GRCh38/hg38)
Size:
29,319 bases
Orientation:
Plus strand
chrX:13,671,225-13,700,083
(GRCh37/hg19)

Genomic View for TCEANC Gene

Genes around TCEANC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TCEANC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TCEANC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCEANC Gene

Proteins for TCEANC Gene

  • Protein details for TCEANC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N8B7-TEANC_HUMAN
    Recommended name:
    Transcription elongation factor A N-terminal and central domain-containing protein
    Protein Accession:
    Q8N8B7
    Secondary Accessions:
    • A6NI06
    • B2RDM3

    Protein attributes for TCEANC Gene

    Size:
    351 amino acids
    Molecular mass:
    40245 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAC04930.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for TCEANC Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TCEANC Gene

Post-translational modifications for TCEANC Gene

No Post-translational modifications

No data available for DME Specific Peptides for TCEANC Gene

Domains & Families for TCEANC Gene

Gene Families for TCEANC Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for TCEANC Gene

Suggested Antigen Peptide Sequences for TCEANC Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TCEANC: view

No data available for UniProtKB/Swiss-Prot for TCEANC Gene

Function for TCEANC Gene

Gene Ontology (GO) - Molecular Function for TCEANC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with TCEANC: view

Phenotypes for TCEANC Gene

genes like me logo Genes that share phenotypes with TCEANC: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TCEANC Gene

Localization for TCEANC Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TCEANC gene
Compartment Confidence
nucleus 5
mitochondrion 3
peroxisome 2
cytosol 2

Gene Ontology (GO) - Cellular Components for TCEANC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with TCEANC: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for TCEANC Gene

Pathways & Interactions for TCEANC Gene

SuperPathways for TCEANC Gene

No Data Available

Gene Ontology (GO) - Biological Process for TCEANC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with TCEANC: view

No data available for Pathways by source and SIGNOR curated interactions for TCEANC Gene

Drugs & Compounds for TCEANC Gene

No Compound Related Data Available

Transcripts for TCEANC Gene

Unigene Clusters for TCEANC Gene

Transcription elongation factor A (SII) N-terminal and central domain containing:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TCEANC Gene

No ASD Table

Relevant External Links for TCEANC Gene

GeneLoc Exon Structure for
TCEANC
ECgene alternative splicing isoforms for
TCEANC

Expression for TCEANC Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TCEANC Gene

NURSA nuclear receptor signaling pathways regulating expression of TCEANC Gene:

TCEANC

SOURCE GeneReport for Unigene cluster for TCEANC Gene:

Hs.222855

Evidence on tissue expression from TISSUES for TCEANC Gene

  • Intestine(4.1)
  • Skin(4)
genes like me logo Genes that share expression patterns with TCEANC: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for TCEANC Gene

Orthologs for TCEANC Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TCEANC Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TCEANC 33 34
  • 99.39 (n)
dog
(Canis familiaris)
Mammalia TCEANC 33 34
  • 84.3 (n)
rat
(Rattus norvegicus)
Mammalia Tceanc 33
  • 80.27 (n)
mouse
(Mus musculus)
Mammalia Tceanc 33 16 34
  • 79.75 (n)
cow
(Bos Taurus)
Mammalia TCEANC 33
  • 75.58 (n)
-- 34
  • 65 (a)
OneToMany
-- 34
  • 63 (a)
OneToMany
chicken
(Gallus gallus)
Aves TCEANC 33 34
  • 62.74 (n)
lizard
(Anolis carolinensis)
Reptilia TCEANC 34
  • 42 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tceanc 33
  • 58.15 (n)
Str.12985 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.17490 33
zebrafish
(Danio rerio)
Actinopterygii LOC100150588 33
  • 52.99 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG8117 34
  • 38 (a)
ManyToMany
TfIIS 34
  • 27 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea T24H10.1 34
  • 24 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes DST1 34
  • 19 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2769 34
  • 24 (a)
OneToMany
Species where no ortholog for TCEANC was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TCEANC Gene

ENSEMBL:
Gene Tree for TCEANC (if available)
TreeFam:
Gene Tree for TCEANC (if available)

Paralogs for TCEANC Gene

Paralogs for TCEANC Gene

(3) SIMAP similar genes for TCEANC Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TCEANC: view

Variants for TCEANC Gene

Sequence variations from dbSNP and Humsavar for TCEANC Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1000272725 -- 13,661,471(+) T/C intron_variant
rs1000425709 -- 13,653,525(+) A/G intron_variant
rs1000494438 -- 13,663,993(+) C/T 3_prime_UTR_variant
rs1000563321 -- 13,654,123(+) C/T intron_variant
rs1000862401 -- 13,653,223(+) C/G 5_prime_UTR_variant, intron_variant

Variation tolerance for TCEANC Gene

Residual Variation Intolerance Score: 54.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.96; 36.35% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for TCEANC Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TCEANC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TCEANC Gene

Disorders for TCEANC Gene

Additional Disease Information for TCEANC

No disorders were found for TCEANC Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TCEANC Gene

Publications for TCEANC Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 58
  4. Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage. (PMID: 25184681) Hill SJ … Livingston DM (Genes & development 2014) 3 58
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58

Products for TCEANC Gene

Sources for TCEANC Gene

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