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Aliases for TCEAL9 Gene

Aliases for TCEAL9 Gene

  • Transcription Elongation Factor A Like 9 2 3
  • WW Domain Binding Protein 5 2 3 5
  • WBP5 3 4 5
  • Pp21 Homolog 2 3
  • WBP-5 3 4
  • WW Domain Binding Protein 1 3
  • WEX6 3

External Ids for TCEAL9 Gene

Previous HGNC Symbols for TCEAL9 Gene

  • WBP5

Summaries for TCEAL9 Gene

Entrez Gene Summary for TCEAL9 Gene

  • The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein. This gene also encodes a domain with similarity to the transcription elongation factor A, SII-related family. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]

GeneCards Summary for TCEAL9 Gene

TCEAL9 (Transcription Elongation Factor A Like 9) is a Protein Coding gene. An important paralog of this gene is TCEAL1.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCEAL9 Gene

Genomics for TCEAL9 Gene

Regulatory Elements for TCEAL9 Gene

Enhancers for TCEAL9 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TCEAL9 on UCSC Golden Path with GeneCards custom track

Promoters for TCEAL9 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TCEAL9 on UCSC Golden Path with GeneCards custom track

Genomic Location for TCEAL9 Gene

Chromosome:
X
Start:
103,356,445 bp from pter
End:
103,358,469 bp from pter
Size:
2,025 bases
Orientation:
Plus strand

Genomic View for TCEAL9 Gene

Genes around TCEAL9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TCEAL9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TCEAL9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCEAL9 Gene

Proteins for TCEAL9 Gene

  • Protein details for TCEAL9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UHQ7-WBP5_HUMAN
    Recommended name:
    WW domain-binding protein 5
    Protein Accession:
    Q9UHQ7
    Secondary Accessions:
    • B2R5H6

    Protein attributes for TCEAL9 Gene

    Size:
    104 amino acids
    Molecular mass:
    12749 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TCEAL9 Gene

Proteomics data for TCEAL9 Gene at MOPED

Post-translational modifications for TCEAL9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TCEAL9 Gene

No data available for DME Specific Peptides for TCEAL9 Gene

Domains & Families for TCEAL9 Gene

Gene Families for TCEAL9 Gene

Protein Domains for TCEAL9 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TCEAL9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UHQ7

UniProtKB/Swiss-Prot:

WBP5_HUMAN :
  • Belongs to the TFS-II family. TFA subfamily.
Family:
  • Belongs to the TFS-II family. TFA subfamily.
genes like me logo Genes that share domains with TCEAL9: view

Function for TCEAL9 Gene

Phenotypes for TCEAL9 Gene

genes like me logo Genes that share phenotypes with TCEAL9: view

Animal Models for TCEAL9 Gene

MGI Knock Outs for TCEAL9:
  • Wbp5 tm1a(KOMP)Wtsi

Animal Model Products

miRNA for TCEAL9 Gene

miRTarBase miRNAs that target TCEAL9

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TCEAL9 Gene

Localization for TCEAL9 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TCEAL9 Gene

Pathways & Interactions for TCEAL9 Gene

SuperPathways for TCEAL9 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TCEAL9 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TCEAL9 Gene

Drugs & Compounds for TCEAL9 Gene

No Compound Related Data Available

Transcripts for TCEAL9 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TCEAL9 Gene

No ASD Table

Relevant External Links for TCEAL9 Gene

GeneLoc Exon Structure for
TCEAL9
ECgene alternative splicing isoforms for
TCEAL9

Expression for TCEAL9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expression patterns with TCEAL9: view

No data available for mRNA expression in normal human tissues , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TCEAL9 Gene

Orthologs for TCEAL9 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TCEAL9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia WBP5 35
  • 89.87 (n)
  • 86.08 (a)
WBP5 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia WBP5 35
  • 89.74 (n)
  • 79.61 (a)
WBP5 36
  • 76 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Wbp5 35
  • 83.33 (n)
  • 74.04 (a)
Wbp5 16
Wbp5 36
  • 74 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia WBP5 35
  • 100 (n)
  • 100 (a)
WBP5 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Wbp5 35
  • 87.18 (n)
  • 80.77 (a)
Species with no ortholog for TCEAL9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TCEAL9 Gene

ENSEMBL:
Gene Tree for TCEAL9 (if available)
TreeFam:
Gene Tree for TCEAL9 (if available)

Paralogs for TCEAL9 Gene

Paralogs for TCEAL9 Gene

Pseudogenes.org Pseudogenes for TCEAL9 Gene

genes like me logo Genes that share paralogs with TCEAL9: view

Variants for TCEAL9 Gene

Sequence variations from dbSNP and Humsavar for TCEAL9 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs747754819 -- 103,357,670(+) GAGAG(A/G)TAGAC utr-variant-5-prime
rs748477071 -- 103,356,555(+) CGCAG(A/G)CGGTG utr-variant-5-prime
rs749226455 -- 103,358,373(+) ATGAT(C/T)TTTCT utr-variant-3-prime
rs749669955 -- 103,358,015(+) TTTTT(A/G)TCTGA utr-variant-3-prime
rs749702866 -- 103,356,647(+) AGTGT(G/T)GGGGG intron-variant

Variation tolerance for TCEAL9 Gene

Residual Variation Intolerance Score: 42.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.37; 8.10% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for TCEAL9 Gene

Disorders for TCEAL9 Gene

Relevant External Links for TCEAL9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TCEAL9
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TCEAL9

No disorders were found for TCEAL9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TCEAL9 Gene

Publications for TCEAL9 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PMID: 16221301) Winter E.E. … Ponting C.P. (BMC Evol. Biol. 2005) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PMID: 17353931) Ewing R.M. … Figeys D. (Mol. Syst. Biol. 2007) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for TCEAL9 Gene

Sources for TCEAL9 Gene

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