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Aliases for TCEAL8 Gene

Aliases for TCEAL8 Gene

  • Transcription Elongation Factor A (SII)-Like 8 2 3
  • Transcription Elongation Factor S-II Protein-Like 8 3 4
  • TCEA-Like Protein 8 3 4
  • Transcription Elongation Factor A Protein-Like 8 3
  • WEX3 3

External Ids for TCEAL8 Gene

Previous GeneCards Identifiers for TCEAL8 Gene

  • GC0XM102314
  • GC0XM102394
  • GC0XM102507
  • GC0XM092171

Summaries for TCEAL8 Gene

Entrez Gene Summary for TCEAL8 Gene

  • This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family contain TFA domains and may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]

GeneCards Summary for TCEAL8 Gene

TCEAL8 (Transcription Elongation Factor A (SII)-Like 8) is a Protein Coding gene. An important paralog of this gene is TCEAL7.

UniProtKB/Swiss-Prot for TCEAL8 Gene

  • May be involved in transcriptional regulation

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCEAL8 Gene

Genomics for TCEAL8 Gene

Regulatory Elements for TCEAL8 Gene

Genomic Location for TCEAL8 Gene

103,252,995 bp from pter
103,255,203 bp from pter
2,209 bases
Minus strand

Genomic View for TCEAL8 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TCEAL8 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCEAL8 Gene

Proteins for TCEAL8 Gene

  • Protein details for TCEAL8 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transcription elongation factor A protein-like 8
    Protein Accession:
    Secondary Accessions:

    Protein attributes for TCEAL8 Gene

    117 amino acids
    Molecular mass:
    13616 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TCEAL8 Gene

Proteomics data for TCEAL8 Gene at MOPED

Post-translational modifications for TCEAL8 Gene

  • Ubiquitination at Lys62
  • Modification sites at PhosphoSitePlus

Other Protein References for TCEAL8 Gene

Antibody Products

No data available for DME Specific Peptides for TCEAL8 Gene

Domains for TCEAL8 Gene

Protein Domains for TCEAL8 Gene


Suggested Antigen Peptide Sequences for TCEAL8 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TFS-II family. TFA subfamily.
  • Belongs to the TFS-II family. TFA subfamily.
genes like me logo Genes that share domains with TCEAL8: view

No data available for Gene Families for TCEAL8 Gene

Function for TCEAL8 Gene

Molecular function for TCEAL8 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation

Animal Model Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TCEAL8

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TCEAL8 Gene

Localization for TCEAL8 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TCEAL8 Gene

Subcellular locations from

Jensen Localization Image for TCEAL8 Gene COMPARTMENTS Subcellular localization image for TCEAL8 gene
Compartment Confidence
nucleus 4
cytosol 2
extracellular 1

Gene Ontology (GO) - Cellular Components for TCEAL8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with TCEAL8: view

Pathways for TCEAL8 Gene

SuperPathways for TCEAL8 Gene

No Data Available

Interacting Proteins for TCEAL8 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: Q8IYN2-TCAL8_HUMAN ENSP00000353093 for TCEAL8 Gene via I2D STRING

Gene Ontology (GO) - Biological Process for TCEAL8 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with TCEAL8: view

No data available for Pathways by source for TCEAL8 Gene

Transcripts for TCEAL8 Gene

mRNA/cDNA for TCEAL8 Gene

Unigene Clusters for TCEAL8 Gene

Transcription elongation factor A (SII)-like 8:
Representative Sequences:

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TCEAL8

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TCEAL8 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c
SP3: - -

Relevant External Links for TCEAL8 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TCEAL8 Gene

mRNA expression in normal human tissues for TCEAL8 Gene

Protein differential expression in normal tissues for TCEAL8 Gene

This gene is overexpressed in NK cells (40.7), Fetal gut (20.8), and Platelet (6.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TCEAL8 Gene

SOURCE GeneReport for Unigene cluster for TCEAL8 Gene Hs.389734

genes like me logo Genes that share expressions with TCEAL8: view

Expression partners for TCEAL8 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TCEAL8 Gene

Orthologs for TCEAL8 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TCEAL8 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TCEAL8 35
  • 93.45 (n)
  • 92.31 (a)
  • 92 (a)
(Canis familiaris)
Mammalia TCEAL8 35
  • 92.88 (n)
  • 93.16 (a)
-- 36
  • 81 (a)
-- 36
  • 93 (a)
(Mus musculus)
Mammalia Tceal8 35
  • 79.49 (n)
  • 72.65 (a)
Tceal8 16
Tceal8 36
  • 73 (a)
(Pan troglodytes)
Mammalia TCEAL8 35
  • 99.72 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Tceal8 35
  • 80.34 (n)
  • 72.65 (a)
Species with no ortholog for TCEAL8:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TCEAL8 Gene

Gene Tree for TCEAL8 (if available)
Gene Tree for TCEAL8 (if available)

Paralogs for TCEAL8 Gene

Paralogs for TCEAL8 Gene

(3) SIMAP similar genes for TCEAL8 Gene using alignment to 2 proteins: Pseudogenes for TCEAL8 Gene

genes like me logo Genes that share paralogs with TCEAL8: view

Variants for TCEAL8 Gene

Sequence variations from dbSNP and Humsavar for TCEAL8 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs3887116 -- 103,252,630(+) CGGTG(A/G)GGTTT downstream-variant-500B
rs4596815 -- 103,253,613(+) TATTA(G/T)GCAAA utr-variant-3-prime
rs5987713 -- 103,256,987(+) TAAAT(G/T)ATTTC upstream-variant-2KB
rs6621636 -- 103,257,112(+) CTGAG(C/T)AGTAT upstream-variant-2KB
rs17285060 -- 103,255,949(+) TTTCA(C/T)TGATG upstream-variant-2KB

Relevant External Links for TCEAL8 Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TCEAL8 Gene

Disorders for TCEAL8 Gene

No disorders were found for TCEAL8 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TCEAL8 Gene

Publications for TCEAL8 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  3. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PMID: 16221301) Winter E.E. … Ponting C.P. (BMC Evol. Biol. 2005) 2 3
  4. Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways. (PMID: 18624398) Wang J. … He F. (J. Proteome Res. 2008) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for TCEAL8 Gene

Sources for TCEAL8 Gene

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