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Aliases for TCEAL6 Gene

Aliases for TCEAL6 Gene

  • Transcription Elongation Factor A (SII)-Like 6 2 3
  • Transcription Elongation Factor S-II Protein-Like 6 3 4
  • TCEA-Like Protein 6 3 4
  • Transcription Elongation Factor A Protein-Like 6 3
  • Transcription Elongation Factor A (SII)-Like 3 3
  • Tceal3 3
  • WEX2 3

External Ids for TCEAL6 Gene

Summaries for TCEAL6 Gene

GeneCards Summary for TCEAL6 Gene

TCEAL6 (Transcription Elongation Factor A (SII)-Like 6) is a Protein Coding gene. An important paralog of this gene is TCEAL3.

UniProtKB/Swiss-Prot for TCEAL6 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCEAL6 Gene

Genomics for TCEAL6 Gene

Genomic Location for TCEAL6 Gene

Start:
102,139,961 bp from pter
End:
102,142,970 bp from pter
Size:
3,010 bases
Orientation:
Minus strand

Genomic View for TCEAL6 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TCEAL6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCEAL6 Gene

Regulatory Elements for TCEAL6 Gene

Proteins for TCEAL6 Gene

  • Protein details for TCEAL6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6IPX3-TCAL6_HUMAN
    Recommended name:
    Transcription elongation factor A protein-like 6
    Protein Accession:
    Q6IPX3
    Secondary Accessions:
    • Q5H9J8

    Protein attributes for TCEAL6 Gene

    Size:
    200 amino acids
    Molecular mass:
    22298 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TCEAL6 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TCEAL6 Gene

Proteomics data for TCEAL6 Gene at MOPED

Post-translational modifications for TCEAL6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TCEAL6 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TCEAL6 Gene

Domains for TCEAL6 Gene

Protein Domains for TCEAL6 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

TCAL6_HUMAN
Family:
  • Belongs to the TFS-II family. TFA subfamily.:
    • Q6IPX3
genes like me logo Genes that share domains with TCEAL6: view

No data available for Gene Families for TCEAL6 Gene

Function for TCEAL6 Gene

Molecular function for TCEAL6 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TCEAL6 Gene

Localization for TCEAL6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TCEAL6 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TCEAL6 Gene COMPARTMENTS Subcellular localization image for TCEAL6 gene
Compartment Confidence
nucleus 4
cytosol 2

Gene Ontology (GO) - Cellular Components for TCEAL6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with TCEAL6: view

Pathways for TCEAL6 Gene

SuperPathways for TCEAL6 Gene

No Data Available

Interacting Proteins for TCEAL6 Gene

Selected Interacting proteins: Q6IPX3-TCAL6_HUMAN for TCEAL6 Gene via I2D

Symbol External ID(s) Details
SMAD2

Gene Ontology (GO) - Biological Process for TCEAL6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with TCEAL6: view

No data available for Pathways by source for TCEAL6 Gene

Transcripts for TCEAL6 Gene

mRNA/cDNA for TCEAL6 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(16) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TCEAL6 Gene

Transcription elongation factor A (SII)-like 6:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TCEAL6 Gene

No ASD Table

Relevant External Links for TCEAL6 Gene

GeneLoc Exon Structure for
TCEAL6
ECgene alternative splicing isoforms for
TCEAL6

Expression for TCEAL6 Gene

mRNA expression in normal human tissues for TCEAL6 Gene

mRNA differential expression in normal tissues according to GTEx for TCEAL6 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (5.1), Brain - Cerebellar Hemisphere (4.9), Brain - Hypothalamus (4.8), Pituitary (4.6), Brain - Cortex (4.6), and Brain - Anterior cingulate cortex (BA24) (4.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TCEAL6 Gene

SOURCE GeneReport for Unigene cluster for TCEAL6 Gene Hs.447815

genes like me logo Genes that share expressions with TCEAL6: view

Orthologs for TCEAL6 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TCEAL6 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TCEAL3 36
  • 96.15 (n)
  • 95.6 (a)
TCEAL6 37
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 68 (a)
ManyToMany
-- 37
  • 72 (a)
ManyToMany
-- 37
  • 69 (a)
ManyToMany
-- 37
  • 73 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Tceal3 37
  • 62 (a)
ManyToMany
Tceal5 37
  • 60 (a)
ManyToMany
Tceal6 36
  • 79.26 (n)
  • 69.44 (a)
Tceal6 37
  • 62 (a)
ManyToMany
Species with no ortholog for TCEAL6:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TCEAL6 Gene

ENSEMBL:
Gene Tree for TCEAL6 (if available)
TreeFam:
Gene Tree for TCEAL6 (if available)

Paralogs for TCEAL6 Gene

Paralogs for TCEAL6 Gene

Selected SIMAP similar genes for TCEAL6 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TCEAL6: view

Variants for TCEAL6 Gene

Sequence variations from dbSNP and Humsavar for TCEAL6 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2001045 -- 102,139,669(-) ATACT(G/T)CCATG downstream-variant-500B
rs2105853 -- 102,144,053(-) aaatc(A/G)taaac upstream-variant-2KB
rs3752340 -- 102,140,648(+) AAAGC(A/G)TTGGG utr-variant-3-prime
rs4898335 -- 102,144,326(+) ttaaa(C/G)tattt upstream-variant-2KB
rs5986847 -- 102,143,112(+) CGGTA(C/T)GTAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TCEAL6 Gene

Variant ID Type Subtype PubMed ID
nsv469670 CNV Complex 16826518

Relevant External Links for TCEAL6 Gene

HapMap Linkage Disequilibrium report
TCEAL6

Disorders for TCEAL6 Gene

No disorders were found for TCEAL6 Gene.

No data available for UniProtKB/Swiss-Prot for TCEAL6 Gene

Publications for TCEAL6 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  3. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PMID: 16221301) Winter E.E. … Ponting C.P. (BMC Evol. Biol. 2005) 2 3
  4. A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening. (PMID: 22379092) Shamay M. … Hayward S.D. (J. Virol. 2012) 3
  5. A COFRADIC protocol to study protein ubiquitination. (PMID: 24816145) Stes E. … Gevaert K. (J. Proteome Res. 2014) 3

Products for TCEAL6 Gene

Sources for TCEAL6 Gene

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