TCEAL5 Gene
protein-coding GIFtS: 37
GCID: GC0XM102528
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transcription elongation factor A (SII)-like 5
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Aliases
for TCEAL5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Transcription Elongation Factor A (SII)-Like 51 2 | | Transcription Elongation Factor S-II Protein-Like 52 3 | | TCEA-Like Protein 52 3 | | Transcription Elongation Factor A Protein-Like 52 |
Export aliases for TCEAL5 gene to outside databasesPrevious GC identifers: GC0XM102334 GC0XM102415 GC0XM092191 |
Summaries
for TCEAL5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TCEAL5:
This gene, which is located on the X chromosome, encodes a protein which contains a BEX (brain expressed X-liked likefamily) domain. This domain is found in proteins encoded by the TCEAL elongation factor (transcription elongationfactor A (SII)-like) gene family also located on the X chromosome. The coding region for this gene is located entirelyin the terminal exon. (provided by RefSeq, Sep 2011)
UniProtKB/Swiss-Prot: TCAL5_HUMAN, Q5H9L2Function: May be involved in transcriptional regulation
|
Genomic Views
for TCEAL5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011651.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TCEAL5 gene promoter:
SRF USF1 p53 SRF (504 AA) Bach2 ATF-2 USF2 USF-1:USF-2 USF-1 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for TCEAL5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCEAL5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq22.1 Ensembl cytogenetic band: Xq22.1 HGNC cytogenetic band: Xq22.2TCEAL5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM102528: view genomic region
(about GC identifiers)
Start:
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102,528,618 bp from pter |
End:
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102,531,800 bp from pter |
Size:
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3,183 bases |
Orientation:
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minus strand |
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Proteins
for TCEAL5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TCAL5_HUMAN, Q5H9L2 (See
protein sequence)Recommended Name: Transcription elongation factor A protein-like 5 Size: 206 amino acids; 23307 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: A2RUJ4Explore the universe of human proteins at neXtProt for TCEAL5: NX_Q5H9L2
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5H9L2
TCEAL5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001012997.1
ENSEMBL proteins: ENSP00000361765
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
TCEAL5 for ontologies About GeneDecksing
TCEAL5 Antibody Products:
Assay Products for TCEAL5: |
Protein
Domains /
Families
for TCEAL5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TCEAL5 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q5H9L2ProtoNet protein and cluster: Q5H9L2 UniProtKB/Swiss-Prot: TCAL5_HUMAN, Q5H9L2Similarity: Belongs to the TFS-II family. TFA subfamily |
Function
for TCEAL5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TCAL5_HUMAN, Q5H9L2Function: May be involved in transcriptional regulation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TCEAL5 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TCEAL5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TCEAL5 (NM_001012979) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TCEAL5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCEAL5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCEAL5 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- |
TCEAL5 for ontologies About GeneDecksing
|
Pathways & Interactions
for TCEAL5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TCEAL5
4 Interacting proteins for TCEAL5 (Q5H9L21, 3) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
IEA | -- |
TCEAL5 for ontologies About GeneDecksing
|
Drugs & Compounds
for TCEAL5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TCEAL5
Search CenterWatch for drugs/clinical trials and news about TCEAL5 / TCAL5
|
Transcripts
for TCEAL5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TCEAL5 gene: NM_001012979.2 Unigene Cluster for TCEAL5: Transcription elongation factor A (SII)-like 5 Hs.403462 [show with all ESTs]Unigene Representative Sequence: NM_0010129791 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000372680(uc004ejz.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TCEAL5 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TCEAL5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TCEAL5 (NM_001012979) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TCEAL5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCEAL5 |
Additional cDNA sequence: AF086094.1 BC132922.1 BC132924.1 1 DOTS entry: DT.91758200 19 AceView cDNA sequences: CR596252 BX281264 BM678026 CR622925 N64688 BI829620 BU738685 AF086094 AL550633 AI003343 AL526642 BQ637865 CB156671 BX355453 BM725918 BU728483 BM701620 H40081 H39646
GeneLoc Exon Structure
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Expression
for TCEAL5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TCEAL5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
See TCEAL5 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.403462
SABiosciences Custom PCR Arrays for TCEAL5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TCEAL5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TCEAL5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TCEAL5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TCEAL5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCEAL5 |
Orthologs
for TCEAL5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for TCEAL5 (if available)
TreeFam Gene Tree for TCEAL5 (if available) |
Paralogs
for TCEAL5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TCEAL5 gene
- TCEAL32 TCEAL42 TCEAL62 TCEAL22
7 SIMAP similar genes for TCEAL5 using alignment to 1 protein entry: TCAL5_HUMAN:TCEAL3 TCEAL6 TCEAL4 TCEAL2 TCEAL8 WBP5
TCEAL7
TCEAL5 for paralogs About GeneDecksing
|
Genomic Variants
for TCEAL5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TCEAL5 (102528618 - 102531800 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TCEAL5: --
Locus Specific Mutation Databases (LSDB): TCEAL5
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TCEAL5 |
|
Disorders
/ Diseases
for TCEAL5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for TCEAL5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TCEAL5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TCEAL5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)
|
External Searches for TCEAL5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing TCEAL5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TCEAL5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TCEAL5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TCEAL5 | Pharmacogenomics, SNPs, Pathways |
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| | |
About This Section
| Patent Information for TCEAL5 gene:
Search GeneIP for patents involving TCEAL5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TCEAL5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TCEAL5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TCEAL5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TCEAL5 | | | OriGene Protein Over-expression Lysate for TCEAL5 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TCEAL5 | | OriGene 3'-UTR Clone for TCEAL5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TCEAL5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TCEAL5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TCEAL5 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCEAL5 |
|  |  |  | | | | Search ThermoFisher Antibodies for TCEAL5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCEAL5 |
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