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Aliases for TCEAL5 Gene

Aliases for TCEAL5 Gene

  • Transcription Elongation Factor A Like 5 2 3
  • Transcription Elongation Factor A (SII)-Like 5 2 3 5
  • Transcription Elongation Factor S-II Protein-Like 5 3 4
  • TCEA-Like Protein 5 3 4
  • WEX4 3

External Ids for TCEAL5 Gene

Previous GeneCards Identifiers for TCEAL5 Gene

  • GC0XM102334
  • GC0XM102415
  • GC0XM102528
  • GC0XM092191

Summaries for TCEAL5 Gene

Entrez Gene Summary for TCEAL5 Gene

  • This gene, which is located on the X chromosome, encodes a protein which contains a BEX (brain expressed X-liked like family) domain. This domain is found in proteins encoded by the TCEAL elongation factor (transcription elongation factor A (SII)-like) gene family also located on the X chromosome. The coding region for this gene is located entirely in the terminal exon. [provided by RefSeq, Sep 2011]

GeneCards Summary for TCEAL5 Gene

TCEAL5 (Transcription Elongation Factor A Like 5) is a Protein Coding gene. An important paralog of this gene is TCEAL4.

UniProtKB/Swiss-Prot for TCEAL5 Gene

  • May be involved in transcriptional regulation.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCEAL5 Gene

Genomics for TCEAL5 Gene

Regulatory Elements for TCEAL5 Gene

Enhancers for TCEAL5 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TCEAL5 on UCSC Golden Path with GeneCards custom track

Genomic Location for TCEAL5 Gene

103,273,690 bp from pter
103,276,872 bp from pter
3,183 bases
Minus strand

Genomic View for TCEAL5 Gene

Genes around TCEAL5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TCEAL5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TCEAL5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCEAL5 Gene

Proteins for TCEAL5 Gene

  • Protein details for TCEAL5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Transcription elongation factor A protein-like 5
    Protein Accession:
    Secondary Accessions:
    • A2RUJ4

    Protein attributes for TCEAL5 Gene

    206 amino acids
    Molecular mass:
    23307 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TCEAL5 Gene

Proteomics data for TCEAL5 Gene at MOPED

Post-translational modifications for TCEAL5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TCEAL5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TCEAL5 Gene

Domains & Families for TCEAL5 Gene

Gene Families for TCEAL5 Gene

Protein Domains for TCEAL5 Gene


Suggested Antigen Peptide Sequences for TCEAL5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TFS-II family. TFA subfamily.
  • Belongs to the TFS-II family. TFA subfamily.
genes like me logo Genes that share domains with TCEAL5: view

Function for TCEAL5 Gene

Molecular function for TCEAL5 Gene

UniProtKB/Swiss-Prot Function:
May be involved in transcriptional regulation.

Gene Ontology (GO) - Molecular Function for TCEAL5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20195357
genes like me logo Genes that share ontologies with TCEAL5: view

Phenotypes for TCEAL5 Gene

GenomeRNAi human phenotypes for TCEAL5:
genes like me logo Genes that share phenotypes with TCEAL5: view

Animal Model Products

miRNA for TCEAL5 Gene

miRTarBase miRNAs that target TCEAL5

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TCEAL5 Gene

Localization for TCEAL5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TCEAL5 Gene

Subcellular locations from

Jensen Localization Image for TCEAL5 Gene COMPARTMENTS Subcellular localization image for TCEAL5 gene
Compartment Confidence
nucleus 4
cytosol 1
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for TCEAL5 Gene

Pathways & Interactions for TCEAL5 Gene

SuperPathways for TCEAL5 Gene

No Data Available

Interacting Proteins for TCEAL5 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000361765 Q5H9L2-TCAL5_HUMAN for TCEAL5 Gene via STRING UniProtKB I2D

Gene Ontology (GO) - Biological Process for TCEAL5 Gene


No data available for Pathways by source and SIGNOR curated interactions for TCEAL5 Gene

Drugs & Compounds for TCEAL5 Gene

No Compound Related Data Available

Transcripts for TCEAL5 Gene

mRNA/cDNA for TCEAL5 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(19) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TCEAL5 Gene

Transcription elongation factor A (SII)-like 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TCEAL5 Gene

No ASD Table

Relevant External Links for TCEAL5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TCEAL5 Gene

mRNA expression in normal human tissues for TCEAL5 Gene

mRNA differential expression in normal tissues according to GTEx for TCEAL5 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (x4.4), Brain - Anterior cingulate cortex (BA24) (x4.3), and Brain - Cerebellar Hemisphere (x4.2).

Protein differential expression in normal tissues from HIPED for TCEAL5 Gene

This gene is overexpressed in Adrenal (32.1) and Testis (13.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TCEAL5 Gene

SOURCE GeneReport for Unigene cluster for TCEAL5 Gene Hs.403462

genes like me logo Genes that share expression patterns with TCEAL5: view

Protein tissue co-expression partners for TCEAL5 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TCEAL5 Gene

Orthologs for TCEAL5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TCEAL5 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TCEAL3 35
  • 83.73 (n)
  • 70.66 (a)
(Canis familiaris)
Mammalia TCEAL5 35
  • 86.08 (n)
  • 82.52 (a)
-- 36
  • 82 (a)
-- 36
  • 80 (a)
-- 36
  • 83 (a)
-- 36
  • 80 (a)
(Mus musculus)
Mammalia Tceal5 35
  • 79.73 (n)
  • 70.35 (a)
Tceal5 16
Tceal3 36
  • 69 (a)
Tceal5 36
  • 73 (a)
Tceal6 36
  • 70 (a)
(Pan troglodytes)
Mammalia TCEAL5 35
  • 99.19 (n)
  • 99.03 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Tceal5 35
  • 79.23 (n)
  • 68.84 (a)
Species with no ortholog for TCEAL5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TCEAL5 Gene

Gene Tree for TCEAL5 (if available)
Gene Tree for TCEAL5 (if available)

Paralogs for TCEAL5 Gene

Paralogs for TCEAL5 Gene

(7) SIMAP similar genes for TCEAL5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TCEAL5: view

Variants for TCEAL5 Gene

Sequence variations from dbSNP and Humsavar for TCEAL5 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs747707611 -- 103,278,731(+) AGACA(C/T)AAATA upstream-variant-2KB
rs747751464 -- 103,277,150(+) TCTAA(C/T)TCTAC upstream-variant-2KB
rs747896340 -- 103,274,255(+) TTTTC(A/G)GCGGC reference, synonymous-codon
rs747926026 -- 103,274,217(+) TTTTT(-/GC)TTTCC reference, frameshift-variant
rs748424013 -- 103,278,224(+) CACCC(C/G)CAAAC upstream-variant-2KB

Variation tolerance for TCEAL5 Gene

Residual Variation Intolerance Score: 54% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.37; 70.94% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for TCEAL5 Gene

Disorders for TCEAL5 Gene

Relevant External Links for TCEAL5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TCEAL5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TCEAL5 Gene

Publications for TCEAL5 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PMID: 16221301) Winter E.E. … Ponting C.P. (BMC Evol. Biol. 2005) 2 3
  3. A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PMID: 20195357) Miyamoto-Sato E. … Yanagawa H. (PLoS ONE 2010) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for TCEAL5 Gene

Sources for TCEAL5 Gene