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Aliases for TCEAL5 Gene

Aliases for TCEAL5 Gene

  • Transcription Elongation Factor A (SII)-Like 5 2 3
  • Transcription Elongation Factor S-II Protein-Like 5 3 4
  • TCEA-Like Protein 5 3 4
  • Transcription Elongation Factor A Protein-Like 5 3
  • WEX4 3

External Ids for TCEAL5 Gene

Previous GeneCards Identifiers for TCEAL5 Gene

  • GC0XM102334
  • GC0XM102415
  • GC0XM102528
  • GC0XM092191

Summaries for TCEAL5 Gene

Entrez Gene Summary for TCEAL5 Gene

  • This gene, which is located on the X chromosome, encodes a protein which contains a BEX (brain expressed X-liked like family) domain. This domain is found in proteins encoded by the TCEAL elongation factor (transcription elongation factor A (SII)-like) gene family also located on the X chromosome. The coding region for this gene is located entirely in the terminal exon. [provided by RefSeq, Sep 2011]

GeneCards Summary for TCEAL5 Gene

TCEAL5 (Transcription Elongation Factor A (SII)-Like 5) is a Protein Coding gene. An important paralog of this gene is TCEAL6.

UniProtKB/Swiss-Prot for TCEAL5 Gene

  • May be involved in transcriptional regulation

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCEAL5 Gene

Genomics for TCEAL5 Gene

Regulatory Elements for TCEAL5 Gene

Genomic Location for TCEAL5 Gene

Start:
103,273,690 bp from pter
End:
103,276,872 bp from pter
Size:
3,183 bases
Orientation:
Minus strand

Genomic View for TCEAL5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TCEAL5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCEAL5 Gene

Proteins for TCEAL5 Gene

  • Protein details for TCEAL5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5H9L2-TCAL5_HUMAN
    Recommended name:
    Transcription elongation factor A protein-like 5
    Protein Accession:
    Q5H9L2
    Secondary Accessions:
    • A2RUJ4

    Protein attributes for TCEAL5 Gene

    Size:
    206 amino acids
    Molecular mass:
    23307 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TCEAL5 Gene

Proteomics data for TCEAL5 Gene at MOPED

Post-translational modifications for TCEAL5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TCEAL5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TCEAL5 Gene

Domains for TCEAL5 Gene

Protein Domains for TCEAL5 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TCEAL5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5H9L2

UniProtKB/Swiss-Prot:

TCAL5_HUMAN :
  • Q5H9L2
Family:
  • Belongs to the TFS-II family. TFA subfamily.
genes like me logo Genes that share domains with TCEAL5: view

No data available for Gene Families for TCEAL5 Gene

Function for TCEAL5 Gene

Molecular function for TCEAL5 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Gene Ontology (GO) - Molecular Function for TCEAL5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 20195357
genes like me logo Genes that share ontologies with TCEAL5: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TCEAL5 Gene

Localization for TCEAL5 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TCEAL5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TCEAL5 Gene COMPARTMENTS Subcellular localization image for TCEAL5 gene
Compartment Confidence
nucleus 4
cytosol 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for TCEAL5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with TCEAL5: view

Pathways for TCEAL5 Gene

SuperPathways for TCEAL5 Gene

No Data Available

Interacting Proteins for TCEAL5 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000361765%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000361765 Q5H9L2-TCAL5_HUMAN for TCEAL5 Gene via STRING UniProtKB I2D

Gene Ontology (GO) - Biological Process for TCEAL5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with TCEAL5: view

No data available for Pathways by source for TCEAL5 Gene

Transcripts for TCEAL5 Gene

mRNA/cDNA for TCEAL5 Gene

(19) Selected AceView cDNA sequences:
(3) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TCEAL5 Gene

Transcription elongation factor A (SII)-like 5:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TCEAL5

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for TCEAL5
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TCEAL5 Gene

No ASD Table

Relevant External Links for TCEAL5 Gene

GeneLoc Exon Structure for
TCEAL5
ECgene alternative splicing isoforms for
TCEAL5

Expression for TCEAL5 Gene

mRNA expression in normal human tissues for TCEAL5 Gene

mRNA differential expression in normal tissues according to GTEx for TCEAL5 Gene

This gene is overexpressed in Brain - Frontal Cortex (BA9) (4.4), Brain - Anterior cingulate cortex (BA24) (4.3), and Brain - Cerebellar Hemisphere (4.2).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TCEAL5 Gene

SOURCE GeneReport for Unigene cluster for TCEAL5 Gene Hs.403462

genes like me logo Genes that share expressions with TCEAL5: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TCEAL5 Gene

Orthologs for TCEAL5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TCEAL5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TCEAL5 35
  • 99.19 (n)
  • 99.03 (a)
TCEAL5 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TCEAL3 35
  • 83.73 (n)
  • 70.66 (a)
dog
(Canis familiaris)
Mammalia -- 36
  • 82 (a)
ManyToMany
-- 36
  • 80 (a)
ManyToMany
-- 36
  • 83 (a)
ManyToMany
-- 36
  • 80 (a)
ManyToMany
TCEAL5 35
  • 86.08 (n)
  • 82.52 (a)
mouse
(Mus musculus)
Mammalia Tceal3 36
  • 69 (a)
ManyToMany
Tceal5 35
  • 79.73 (n)
  • 70.35 (a)
Tceal5 16
Tceal5 36
  • 73 (a)
ManyToMany
Tceal6 36
  • 70 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia Tceal5 35
  • 79.23 (n)
  • 68.84 (a)
Species with no ortholog for TCEAL5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TCEAL5 Gene

ENSEMBL:
Gene Tree for TCEAL5 (if available)
TreeFam:
Gene Tree for TCEAL5 (if available)

Paralogs for TCEAL5 Gene

Paralogs for TCEAL5 Gene

Selected SIMAP similar genes for TCEAL5 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TCEAL5: view

Variants for TCEAL5 Gene

Sequence variations from dbSNP and Humsavar for TCEAL5 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs429796 -- 103,277,563(+) acaca(C/G)acaca upstream-variant-2KB
rs2285085 -- 103,273,722(-) TGTAA(A/C)ATAAC utr-variant-3-prime
rs3015331 -- 103,274,801(-) TAAAT(G/T)TAGGG intron-variant
rs6621640 -- 103,274,262(+) CGGCC(C/G/T)GCGGC missense, reference
rs6621641 -- 103,277,758(+) ATGCA(A/G)AAATG upstream-variant-2KB

Relevant External Links for TCEAL5 Gene

HapMap Linkage Disequilibrium report
TCEAL5
Locus Specific Mutation Databases (LSDB)
TCEAL5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TCEAL5 Gene

Disorders for TCEAL5 Gene

No disorders were found for TCEAL5 Gene.

No data available for UniProtKB/Swiss-Prot for TCEAL5 Gene

Publications for TCEAL5 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  2. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PMID: 16221301) Winter E.E. … Ponting C.P. (BMC Evol. Biol. 2005) 2 3
  3. A comprehensive resource of interacting protein regions for refining human transcription factor networks. (PMID: 20195357) Miyamoto-Sato E. … Yanagawa H. (PLoS ONE 2010) 3
  4. A COFRADIC protocol to study protein ubiquitination. (PMID: 24816145) Stes E. … Gevaert K. (J. Proteome Res. 2014) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for TCEAL5 Gene

Sources for TCEAL5 Gene

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