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TCEAL1 Gene

protein-coding   GIFtS: 56
GCID: GC0XP102883

Transcription Elongation Factor A (SII)-Like 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transcription Elongation Factor A (SII)-Like 11 2     WEX92
SIIR2 3 5     p212
Nuclear Phosphoprotein P21/SIIR2 3     pp212
Transcription Elongation Factor S-II Protein-Like 12 3     Transcription Elongation Factor A Protein-Like 12
TCEA-Like Protein 12 3     P215

External Ids:    HGNC: 116161   Entrez Gene: 93382   Ensembl: ENSG000001724657   OMIM: 3002375   UniProtKB: Q151703   

Export aliases for TCEAL1 gene to outside databases

Previous GC identifers: GC0XP098185 GC0XP099792 GC0XP100916 GC0XP101655 GC0XP102690 GC0XP102770 GC0XP092540


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TCEAL1 Gene:
This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of
this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent
manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains
a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It
may exert its effects via protein-protein interactions with other transcriptional regulators rather than via
direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in
multiple transcript variants encoding a single isoform. (provided by RefSeq, Jul 2008)

GeneCards Summary for TCEAL1 Gene:
TCEAL1 (transcription elongation factor A (SII)-like 1) is a protein-coding gene. Diseases associated with TCEAL1 include primary open angle glaucoma, and open-angle glaucoma. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity. An important paralog of this gene is WBP5.

UniProtKB/Swiss-Prot: TCAL1_HUMAN, Q15170
Function: May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a
promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous
sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly

Gene Wiki entry for TCEAL1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NC_018934.2  NT_011651.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the TCEAL1 gene promoter:
         p53   GATA-3   FOXD3   POU6F1 (c2)   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTCEAL1 promoter sequence
   Search Chromatin IP Primers for TCEAL1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TCEAL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.1   Ensembl cytogenetic band:  Xq22.2   HGNC cytogenetic band: Xq22.1

TCEAL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCEAL1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP102883:  view genomic region     (about GC identifiers)

Start:
102,883,632 bp from pter      End:
102,885,881 bp from pter
Size:
2,250 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TCAL1_HUMAN, Q15170 (See protein sequence)
Recommended Name: Transcription elongation factor A protein-like 1  
Size: 157 amino acids; 18354 Da
Secondary accessions: Q9UJQ9
Alternative splicing: 2 isoforms:  Q15170-1   Q15170-2   (Contains a phosphoserine at position 28)

Explore the universe of human proteins at neXtProt for TCEAL1: NX_Q15170

Explore proteomics data for TCEAL1 at MOPED

Post-translational modifications: 

  • Phosphorylation of Ser-36 and Ser-37 is critical for transcriptional repression1
  • Ubiquitination2 at Lys136
  • Modification sites at PhosphoSitePlus

  • See TCEAL1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001006640.1  NP_001006641.1  NP_004771.2  

    ENSEMBL proteins: 
     ENSP00000361709   ENSP00000361708   ENSP00000361707  

    TCEAL1 Human Recombinant Protein Products:

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    Novus Biologicals TCEAL1 Proteins
    Novus Biologicals TCEAL1 Lysates
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    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for TCEAL1
    Cloud-Clone Corp. Proteins for TCEAL1

    TCEAL1 Antibody Products:

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    Cloud-Clone Corp. CLIAs for TCEAL1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR021156 TF_A-like/BEX-like
     IPR010370 TFA

    Graphical View of Domain Structure for InterPro Entry Q15170

    ProtoNet protein and cluster: Q15170

    UniProtKB/Swiss-Prot: TCAL1_HUMAN, Q15170
    Similarity: Belongs to the TFS-II family. TFA subfamily


    TCEAL1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TCAL1_HUMAN, Q15170
    Function: May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a
    promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous
    sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly

         Genatlas biochemistry entry for TCEAL1:
    transcription elongation factor A-like 1,widely expressed,modulating transcription in a promoter context-dependent
    fashion

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003700sequence-specific DNA binding transcription factor activity NAS7971997
    GO:0005515protein binding ----
         
    TCEAL1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for TCEAL1:
     Decreased POU5F1-GFP protein e  Decreased viability of wild-ty 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TCEAL1
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TCEAL1

    miRNA
    Products:
        
    miRTarBase miRNAs that target TCEAL1:
    hsa-mir-504-5p (MIRT016255), hsa-mir-106b-5p (MIRT005847), hsa-mir-605-5p (MIRT016156), hsa-mir-663a (MIRT006732), hsa-mir-22-3p (MIRT006444), hsa-mir-221-3p (MIRT005789), hsa-mir-222-3p (MIRT005792), hsa-mir-26b-5p (MIRT029229)

    Block miRNA regulation of human, mouse, rat TCEAL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TCEAL1 (see all 23):
    hsa-miR-520e hsa-miR-302d hsa-miR-448 hsa-miR-539 hsa-miR-520d-5p hsa-miR-302e hsa-miR-519a hsa-miR-410
    SwitchGear 3'UTR luciferase reporter plasmidTCEAL1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TCEAL1
    Predesigned siRNA for gene silencing in human, mouse, rat TCEAL1

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 3): TCEAL1 (NM_004780)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TCEAL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCEAL1

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCEAL1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TCAL1_HUMAN, Q15170: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    TCEAL1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TCEAL1
    Interactions:

        GeneGlobe Interaction Network for TCEAL1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TCEAL1 (Q151703 ENSP000003617074) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CUL2Q136173, ENSP000003638804I2D: score=2 STRING: ENSP00000363880
    KDM3AQ9Y4C13, ENSP000003236594I2D: score=2 STRING: ENSP00000323659
    PDCD5O147373, ENSP000002217844I2D: score=2 STRING: ENSP00000221784
    RFC1P352513, ENSP000002614244I2D: score=2 STRING: ENSP00000261424
    HOXB6P175093, ENSP000002256484I2D: score=1 STRING: ENSP00000225648
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter TAS7971997
    GO:0006351transcription, DNA-templated IEA--

    TCEAL1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TCEAL1 (TCAL1)

    5 Novoseek inferred chemical compound relationships for TCEAL1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    gdp 70 5 8318164 (2), 1932015 (1), 1351295 (1), 8142894 (1)
    gtp 53.2 5 1351295 (2), 8318164 (2)
    guanine 48.4 2 8142894 (1)
    hydrogen 16.3 3 8142894 (2), 1932015 (1)
    tyrosine 14.1 2 1351295 (1), 8193543 (1)



    TCEAL1 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TCEAL1 gene (3 alternative transcripts): 
    NM_001006639.1  NM_001006640.1  NM_004780.2  

    Unigene Cluster for TCEAL1:

    Transcription elongation factor A (SII)-like 1
    Hs.95243  [show with all ESTs]
    Unigene Representative Sequence: NM_004780
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372626 ENST00000372625(uc004ekt.3 uc004eku.3) ENST00000469820
    ENST00000372624(uc004eks.3)
    miRNA
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    Block miRNA regulation of human, mouse, rat TCEAL1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TCEAL1 (see all 23):
    hsa-miR-520e hsa-miR-302d hsa-miR-448 hsa-miR-539 hsa-miR-520d-5p hsa-miR-302e hsa-miR-519a hsa-miR-410
    SwitchGear 3'UTR luciferase reporter plasmidTCEAL1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TCEAL1
    Predesigned siRNA for gene silencing in human, mouse, rat TCEAL1
    Clone
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    OriGene ORF clones in mouse, rat for TCEAL1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): TCEAL1 (NM_004780)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TCEAL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCEAL1
    Primer
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    OriGene qPCR primer pairs and template standards for TCEAL1
    OriGene qSTAR qPCR primer pairs in human, mouse for TCEAL1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TCEAL1
      QuantiTect SYBR Green Assays in human, mouse, rat TCEAL1
      QuantiFast Probe-based Assays in human, mouse, rat TCEAL1

    Additional mRNA sequence: 

    BC000809.1 M99701.1 

    6 DOTS entries:

    DT.115566  DT.100025362  DT.91720648  DT.121301124  DT.121301122  DT.40213593 

    Selected AceView cDNA sequences (see all 182):

    AA902540 BQ014180 CA502741 BF431895 BU676815 AI215599 AI097048 AW161297 
    BU736625 BM708086 BU681984 BM315031 AW518587 BC007622 AI498256 BE350778 
    AF163263 BC000809 BI754447 AW263944 AI004196 CB160805 BG760935 AA916195 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TCEAL1 (see all 6)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c · 5d · 5e
    SP1:        -     -     -     -           -     -                                 
    SP2:                          -                 -                                 
    SP3:                          -           -     -                                 
    SP4:                          -                                                   
    SP5:                                      -     -                                 


    ECgene alternative splicing isoforms for TCEAL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TCEAL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAGATGTAC
    TCEAL1 Expression
    About this image


    TCEAL1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Pre-Granulosa Cells Primordial Follicle
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Adrenal Gland (Endocrine System)
     
     Uterus (Reproductive System)
     
     Prostate (Endocrine System)
    TCEAL1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TCEAL1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.95243

    UniProtKB/Swiss-Prot: TCAL1_HUMAN, Q15170
    Tissue specificity: Expressed in all tissues examined. Highly expressed in heart, ovary, prostate and skeletal
    muscle. Moderately expressed in brain, placenta, testis and small intestine. Weakly expressed in lung, liver and
    spleen. Expressed in several cancer cell lines

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    QuantiFast Probe-based Assays in human, mouse, rat TCEAL1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCEAL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for TCEAL1 gene from Selected species (see all 5)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tceal11 , 5 transcription elongation factor A (SII)-like 11, 5 74.63(n)1
    74.84(a)1
      X (59.10 cM)5
    2370521  NM_146236.11  NP_666348.11 
     1367079825 


    ENSEMBL Gene Tree for TCEAL1 (if available)
    TreeFam Gene Tree for TCEAL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TCEAL1 gene
    WBP52  
    3 SIMAP similar genes for TCEAL1 using alignment to 1 protein entry:     TCAL1_HUMAN:
    WBP5    TCEAL7    TCEAL8

    TCEAL1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TCEAL1 (see all 73)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs20571001,2
    C,F,A,H--102881754(+) aaagtG/Acacaa 1 -- us2k119Minor allele frequency- A:0.20NS EA NA WA CSA 1335
    rs604081001,2
    C,F--102881796(+) TAGTAC/TTGTTA 1 -- us2k11Minor allele frequency- T:0.00WA 2
    rs1900661081,2
    --102881953(+) TTATTA/GTCTCC 3 -- us2k10--------
    rs1814836921,2
    C--102882024(+) CAGAAC/TGGAAG 3 -- us2k10--------
    rs1858282341,2
    --102882056(+) CTGTGA/GCAATT 3 -- us2k10--------
    rs1131516051,2
    C--102882121(+) CTCCAA/CAGGGC 3 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs1402938521,2
    --102882143(+) CAATGA/TGTGTA 3 -- us2k10--------
    rs572119571,2
    C--102882191(+) TAATT-/AATT  
            
    TTAAA
    3 -- us2k10--------
    rs1901496301,2
    --102882775(+) AGATAA/TAAAAA 3 -- us2k10--------
    rs1824635451,2
    --102882784(+) AAAATA/GCATAT 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for TCEAL1 (102883632 - 102885881 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TCEAL1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TCEAL1
    DNA2.0 Custom Variant and Variant Library Synthesis for TCEAL1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300237    OMIM disorders: --

    14 diseases for TCEAL1:    
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    primary open angle glaucoma    open-angle glaucoma    esophageal cancer    glaucoma
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    TCEAL1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TCEAL1
    Human Genome Epidemiology (HuGE) Navigator: TCEAL1 (8 documents)

    Export disorders for TCEAL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TCEAL1 gene, integrated from 10 sources (see all 36):
    (articles sorted by number of sources associating them with TCEAL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A HeLa-cell-encoded p21 is homologous to transcription elongation factor SII. (PubMed id 8206389)1, 2, 3, 9 Yeh C.-H. and Shatkin A.J. (Gene 1994)
    2. Polymorphisms in cell cycle regulatory genes, urinary arsenic profile and urothelial carcinoma. (PubMed id 18640142)1, 4 Chung C.J....Hsueh Y.M. (Toxicol. Appl. Pharmacol. 2008)
    3. Polymorphisms of p53 and p21 genes in chronic obstructive pulmonary disease. (PubMed id 16697770)1, 4 Lee Y.L....Wang Y.C. (J. Lab. Clin. Med. 2006)
    4. Association between TP53 and p21 genetic polymorphisms and acute side effects of radiotherapy in breast cancer patients. (PubMed id 16331344)1, 4 Tan X.L....Chang-Claude J. (Breast Cancer Res. Treat. 2006)
    5. TP53 and P21 polymorphisms: response to cisplatinum/paclitaxel-based chemotherapy in ovarian cancer. (PubMed id 16364249)1, 4 Santos A.M....Medeiros R. (Biochem. Biophys. Res. Commun. 2006)
    6. Linking TP53 codon 72 and P21 nt590 genotypes to the development of cervical and ovarian cancer. (PubMed id 16542834)1, 4 Santos A.M....Medeiros R. (Eur. J. Cancer 2006)
    7. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    8. A polymorphism at codon 31 of gene p21 is not associated with primary open angle glaucoma in Caucasians. (PubMed id 15807891)1, 4 Ressiniotis T....Birch M. (BMC Ophthalmol 2005)
    9. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PubMed id 16221301)1, 3 Winter E.E. and Ponting C.P. (BMC Evol. Biol. 2005)
    10. Lack of evidence that proline homozygosity at codon 72 of p53 and rare arginine allele at codon 31 of p21, jointly mediate cervical cancer susceptibility among Indian women. (PubMed id 16054204)1, 4 Bhattacharya P. and Sengupta S. (Gynecol. Oncol. 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9338 HGNC: 11616 AceView: TCEAL1andTCEAL3 Ensembl:ENSG00000172465 euGenes: HUgn9338
    ECgene: TCEAL1 H-InvDB: TCEAL1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TCEAL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TCEAL1 gene:
    Search GeneIP for patents involving TCEAL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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