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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TCEA3 Gene

protein-coding   GIFtS: 50
GCID: GC01M023706

Transcription Elongation Factor A (SII), 3

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transcription Elongation Factor A (SII), 31 2     TFIIS.H2
Transcription Elongation Factor S-II Protein 32 3     Rhabdomyosarcoma Antigen MU-RMS-40.222
Transcription Elongation Factor TFIIS.H2 3     Transcription Elongation Factor A Protein 32
TFIIS2     TFIISH3

External Ids:    HGNC: 116151   Entrez Gene: 69202   Ensembl: ENSG000002042197   OMIM: 6041285   UniProtKB: O757643   

Export aliases for TCEA3 gene to outside databases

Previous GC identifers: GC01M023264 GC01M022778 GC01M023176 GC01M023177 GC01M023453 GC01M023580 GC01M021959


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TCEA3 Gene: 
TCEA3 (transcription elongation factor A (SII), 3) is a protein-coding gene. Diseases associated with TCEA3 include rhabdomyosarcoma, and conjunctivitis, and among its related super-pathways are Assembly of RNA Polymerase-II Initiation Complex. GO annotations related to this gene include DNA binding and zinc ion binding. An important paralog of this gene is TCEA1.

UniProtKB/Swiss-Prot: TCEA3_HUMAN, O75764
Function: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting
sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases
that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the
resumption of elongation from the new 3'-terminus




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004610.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TCEA3 gene promoter:
         SRF   NRSF form 1   SRF (504 AA)   RREB-1   NRSF form 2   Egr-4   C/EBPalpha   CHOP-10   MZF-1   FOXC1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTCEA3 promoter sequence
   Search SABiosciences Chromatin IP Primers for TCEA3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCEA3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.12   Ensembl cytogenetic band:  1p36.12   HGNC cytogenetic band: 1p36.11

TCEA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCEA3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M023706:  view genomic region     (about GC identifiers)

Start:
23,707,554 bp from pter      End:
23,751,261 bp from pter
Size:
43,708 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TCEA3_HUMAN, O75764 (See protein sequence)
Recommended Name: Transcription elongation factor A protein 3  
Size: 348 amino acids; 38972 Da
Subcellular location: Nucleus (By similarity)
Secondary accessions: A8K2K7

Explore the universe of human proteins at neXtProt for TCEA3: NX_O75764

Explore proteomics data for TCEA3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75764

  • TCEA3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TCEA3 Protein Expression
    REFSEQ proteins: NP_003187.1  
    ENSEMBL proteins: 
     ENSP00000406293   ENSP00000474530   ENSP00000363729   ENSP00000474977  

    Human Recombinant Protein Products for TCEA3: 
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    Novus Biologicals TCEA3 Protein
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TCEA3 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    TCEA3 for ontologies           About GeneDecksing



    TCEA3 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/7 InterPro protein domains (see all 7):
     IPR003617 TFIIS/CRSP70_N_sub
     IPR001222 Znf_TFIIS
     IPR003618 TFIIS_cen_dom
     IPR017923 TFIIS_N
     IPR017890 TFS2M

    Graphical View of Domain Structure for InterPro Entry O75764

    ProtoNet protein and cluster: O75764

    1 Blocks protein domain: IPB003617 Transcription elongation factor S-II

    UniProtKB/Swiss-Prot: TCEA3_HUMAN, O75764
    Similarity: Belongs to the TFS-II family
    Similarity: Contains 1 TFIIS central domain
    Similarity: Contains 1 TFIIS N-terminal domain
    Similarity: Contains 1 TFIIS-type zinc finger


    TCEA3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TCEA3_HUMAN, O75764
    Function: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting
    sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases
    that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the
    resumption of elongation from the new 3'-terminus

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0008270zinc ion binding IEA--
         
    TCEA3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TCEA3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TCEA3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TCEA3 
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    miRNA
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate TCEA3:
    hsa-miR-515-5p hsa-miR-145 hsa-miR-516a-3p hsa-miR-516b* hsa-miR-450b-5p hsa-miR-766 hsa-miR-519e*
    SwitchGear 3'UTR luciferase reporter plasmidTCEA3 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TCEA3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Assembly of RNA Polymerase-II Initiation Complex
    Transcription of mRNA0.91

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for TCEA3
        Transcription of mRNA


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TCEA3

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for TCEA3 (ENSP000004062934) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPH3ALENSP000003192104STRING: ENSP00000319210
    POLR2EENSP000002155874STRING: ENSP00000215587
    POLR2FENSP000004038524STRING: ENSP00000403852
    POLR2IENSP000002218594STRING: ENSP00000221859
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0006357regulation of transcription from RNA polymerase II promoter IEA--
    GO:0032784regulation of DNA-dependent transcription, elongation IEA--

    TCEA3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TCEA3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TCEA3

    2 Novoseek inferred chemical compound relationships for TCEA3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    6-azauracil 86.3 2 12511561 (1), 15780939 (1)
    zinc 24.1 7 1868060 (3), 9724522 (2), 9712887 (1)

    Search CenterWatch for drugs/clinical trials and news about TCEA3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TCEA3 gene: 
    NM_003196.1  

    Unigene Cluster for TCEA3:

    Transcription elongation factor A (SII), 3
    Hs.446354  [show with all ESTs]
    Unigene Representative Sequence: NM_003196
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000450454(uc009vqm.2 uc021oig.1 uc021oih.1 uc010ody.1)
    ENST00000476978 ENST00000374601 ENST00000461794 ENST00000374602 ENST00000492271

    miRNA
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate TCEA3:
    hsa-miR-515-5p hsa-miR-145 hsa-miR-516a-3p hsa-miR-516b* hsa-miR-450b-5p hsa-miR-766 hsa-miR-519e*
    SwitchGear 3'UTR luciferase reporter plasmidTCEA3 3' UTR sequence
    Inhib. RNA
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                         Customized lentivirus expression plasmids for stable overexpression of TCEA3 
    Primer
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    OriGene qPCR primer pairs and template standards for TCEA3
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TCEA3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TCEA3

    Additional mRNA sequence: 

    AJ223473.1 AK027024.1 AK290272.1 AK300707.1 AK310039.1 AY540752.1 BC041613.1 

    11 DOTS entries:

    DT.448657  DT.432013  DT.92420864  DT.100780717  DT.91939517  DT.92420863  DT.91667417  DT.91880930 
    DT.91886475  DT.95072939  DT.95199690 

    24/121 AceView cDNA sequences (see all 121):

    CA449942 AA888058 AI572481 T95597 CA435035 AI669819 NM_003196 AA688241 
    AI193651 AA970866 BE880226 AI861898 BG059665 AJ223473 AI308948 AI202589 
    AI097019 BQ006295 BC041613 CF127872 AI393002 AK027024 AW151718 AA071471 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TCEA3 expression in normal human tissues (normalized intensities)      TCEA3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACAAGGTGA
    TCEA3 Expression
    About this image


    TCEA3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             Normal Human Articular chondrocytes (NHAC)   
     
     Mesenchymal Stem Cells (Integumentary System)    fully expand to see all 2 entries
             Dental pulp Stem Cells (DPSC)   
     
     Heart (Cardiovascular System)
             Cardiomyocyte-like progenitor cells ( Derivation of cardiomyocytes from pluripotent...
     
     Inner Cell Mass (Early Embryonic Tissues)
             Sox17-GFP genetically modified stem cells
     
     Fibroblast
             Human Dermal Fibroblasts-adult (HDF-a)   

    See TCEA3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TCEA3

    SOURCE GeneReport for Unigene cluster: Hs.446354
        SABiosciences Custom PCR Arrays for TCEA3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCEA3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TCEA3 gene from 9/19 species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tcea31 , 5 transcription elongation factor A (SII), 31, 5 89.11(n)1
    91.04(a)1
      4 (68.34 cM)5
    214011  NM_011542.21  NP_035672.11 
     1362477295 
    chicken
    (Gallus gallus)
    Aves LOC1008588971 transcription elongation factor A protein 3-like 65.82(n)
    64.97(a)
      100858897  XM_003642574.1  XP_003642622.1 
    lizard
    (Anolis carolinensis)
    Reptilia TCEA36
    Uncharacterized protein
    72(a)
    1 ↔ 1
    GL343904.1(59829-71600)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.4082 Xenopus laevis mRNA for transcription elongation factor more 74.15(n)    AB040437.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.156342 Transcribed sequence with moderate similarity to protein more 80.7(n)    BM342366.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta TfIIS1 , 3 RNA elongation from Pol II promoter
    transcription more3
    RNA polymerase II elongation factor1
    62(a)
    (best of 2)3
    57.48(n)1
    51.92(a)1
      348831  NM_057619.31  NP_476967.11 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DST16
    General transcription elongation factor TFIIS, ena...
    26(a)
    1 → many
    VII(417483-418412)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons TFIIS1 transcript elongation factor IIS 43.94(n)
    33.77(a)
      818438  NM_129413.3  NP_181390.1 
    rice
    (Oryza sativa)
    Liliopsida Os03g08159001 hypothetical protein 43.57(n)
    30.7(a)
      4334559  NM_001058222.1  NP_001051687.1 


    ENSEMBL Gene Tree for TCEA3 (if available)
    TreeFam Gene Tree for TCEA3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TCEA3 gene
    TCEA12  TCEANC2  TCEA22  
    2 SIMAP similar genes for TCEA3 using alignment to 2 protein entries:     TCEA3_HUMAN (see all proteins):
    TCEA1    TCEA2

    TCEA3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/973 SNPs in TCEA3 are shown (see all 973)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs6515421,2
    C,F,A,H--23707401(-) AGAACA/TGTTGA 1 -- ds500123Minor allele frequency- T:0.17NS EA NA WA CSA 1546
    rs1860544021,2
    --23707429(+) GTGGGA/GGTGGG 1 -- ds50010--------
    rs1133757301,2
    C,F--23707432(+) GGGGTG/CGGGTA 1 -- ds50012Minor allele frequency- C:0.05CSA WA 120
    rs6510361,2
    C,F,H--23707516(-) CAGACC/GTTTGC 1 -- ds500118Minor allele frequency- G:0.19NA NS EA WA CSA 920
    rs31925641,2
    F--23707641(-) cgcttA/Gacccc 1 -- ut311Minor allele frequency- G:0.33MN 184
    rs6501021,2
    C,F--23707692(-) GGTGGC/TTTATG 1 -- ut31 ese312Minor allele frequency- T:0.21MN NA WA CSA EA 556
    rs1388484081,2
    --23707798(+) ATGACC/TGATTA 1 -- ut310--------
    rs1897231041,2
    --23707845(+) ATCCCA/GCTCAG 1 -- ut310--------
    rs786780721,2
    F--23707860(+) AGTTCA/GGTATT 1 -- ut311Minor allele frequency- G:0.01WA 118
    rs1813297161,2
    --23707935(+) CCTCAC/TCTTGT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TCEA3 (23707554 - 23751261 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for TCEA3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2745297CNV Deletion23290073
    esv2661255CNV Deletion23128226
    esv2558689CNV Deletion19546169
    esv2745286CNV Deletion23290073
    nsv512726CNV Insertion21212237
    nsv521882CNV Loss19592680
    esv9540CNV Loss19470904
    dgv28n67CNV Loss20364138

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604128    OMIM disorders: --

    5 diseases for TCEA3:    About MalaCards
    rhabdomyosarcoma    conjunctivitis    acute myeloid leukemia    myeloid leukemia
    leukemia


    TCEA3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TCEA3
    Human Genome Epidemiology (HuGE) Navigator: TCEA3 (3 documents)

    Export disorders for TCEA3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TCEA3 gene, integrated from 9 sources (see all 46):
    (articles sorted by number of sources associating them with TCEA3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of novel genes encoding transcription elongation factor TFIIS (TCEA) in vertebrates: conservation of three distinct TFIIS isoforms in frog, mouse, and human. (PubMed id 9790746)1, 2, 3, 9 Labhart P. and Morgan G.T. (1998)
    2. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    5. The human PAF1 complex acts in chromatin transcriptio n elongation both independently and cooperatively with SII/TFIIS. (PubMed id 20178742)1 Kim J....Roeder R.G. (2010)
    6. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    7. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. The HIV-1 Tat cellular coactivator Tat-SF1 is a general transcription elongation factor. (PubMed id 9765201)1 Li X.-Y. and Green M.R. (1998)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6920 HGNC: 11615 AceView: TCEA3 Ensembl:ENSG00000204219 euGenes: HUgn6920
    ECgene: TCEA3 H-InvDB: TCEA3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TCEA3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TCEA3 gene:
    Search GeneIP for patents involving TCEA3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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