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TCEA3 Gene

protein-coding   GIFtS: 50
GCID: GC01M023706

Transcription Elongation Factor A (SII), 3

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transcription Elongation Factor A (SII), 31 2     TFIIS.H2
Transcription Elongation Factor S-II Protein 32 3     Rhabdomyosarcoma Antigen MU-RMS-40.222
Transcription Elongation Factor TFIIS.H2 3     Transcription Elongation Factor A Protein 32
TFIIS2     TFIISH3

External Ids:    HGNC: 116151   Entrez Gene: 69202   Ensembl: ENSG000002042197   OMIM: 6041285   UniProtKB: O757643   

Export aliases for TCEA3 gene to outside databases

Previous GC identifers: GC01M023264 GC01M022778 GC01M023176 GC01M023177 GC01M023453 GC01M023580 GC01M021959


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TCEA3 Gene:
TCEA3 (transcription elongation factor A (SII), 3) is a protein-coding gene. An important paralog of this gene is TCEA1.

UniProtKB/Swiss-Prot: TCEA3_HUMAN, O75764
Function: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting
sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases
that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the
resumption of elongation from the new 3'-terminus




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TCEA3 gene promoter:
         SRF   NRSF form 1   SRF (504 AA)   RREB-1   NRSF form 2   Egr-4   C/EBPalpha   CHOP-10   MZF-1   FOXC1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTCEA3 promoter sequence
   Search Chromatin IP Primers for TCEA3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TCEA3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.12   Ensembl cytogenetic band:  1p36.12   HGNC cytogenetic band: 1p36.11

TCEA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCEA3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M023706:  view genomic region     (about GC identifiers)

Start:
23,707,554 bp from pter      End:
23,751,261 bp from pter
Size:
43,708 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TCEA3_HUMAN, O75764 (See protein sequence)
Recommended Name: Transcription elongation factor A protein 3  
Size: 348 amino acids; 38972 Da
Secondary accessions: A8K2K7

Explore the universe of human proteins at neXtProt for TCEA3: NX_O75764

Explore proteomics data for TCEA3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TCEA3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_003187.1  
    ENSEMBL proteins: 
     ENSP00000406293   ENSP00000474530   ENSP00000363729   ENSP00000474977  

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    antibodies-online proteins for TCEA3 (4 products) 

     
    antibodies-online peptides for TCEA3

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 7):
     IPR003617 TFIIS/CRSP70_N_sub
     IPR001222 Znf_TFIIS
     IPR003618 TFIIS_cen_dom
     IPR017923 TFIIS_N
     IPR017890 TFS2M

    Graphical View of Domain Structure for InterPro Entry O75764

    ProtoNet protein and cluster: O75764

    1 Blocks protein domain: IPB003617 Transcription elongation factor S-II

    UniProtKB/Swiss-Prot: TCEA3_HUMAN, O75764
    Similarity: Belongs to the TFS-II family
    Similarity: Contains 1 TFIIS central domain
    Similarity: Contains 1 TFIIS N-terminal domain
    Similarity: Contains 1 TFIIS-type zinc finger


    Find genes that share domains with TCEA3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TCEA3_HUMAN, O75764
    Function: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting
    sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases
    that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the
    resumption of elongation from the new 3'-terminus

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0003677DNA binding IEA--
    GO:0008270zinc ion binding IEA--
         
    Find genes that share ontologies with TCEA3           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TCEA3

    miRNA
    Products:
        
    miRTarBase miRNAs that target TCEA3:
    hsa-mir-335-5p (MIRT017460), hsa-mir-24-3p (MIRT030391)

    Block miRNA regulation of human, mouse, rat TCEA3 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate TCEA3:
    hsa-miR-515-5p hsa-miR-145 hsa-miR-516a-3p hsa-miR-516b* hsa-miR-450b-5p hsa-miR-766 hsa-miR-519e*
    SwitchGear 3'UTR luciferase reporter plasmidTCEA3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TCEA3

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: TCEA3 (NM_003196)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCEA3

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TCEA3_HUMAN, O75764: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with TCEA3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TCEA3 About    
    See pathways by source

    SuperPathContained pathways About
    1Assembly of RNA Polymerase-II Initiation Complex
    Transcription of mRNA0.91

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for TCEA3
        Transcription of mRNA


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TCEA3
    Interactions:

        Search GeneGlobe Interaction Network for TCEA3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TCEA3 (ENSP000004062934) via UniProtKB, MINT, STRING, and/or I2D (see all 53)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SUPT4H1ENSP000002255044STRING: ENSP00000225504
    USP10ENSP000002194734STRING: ENSP00000219473
    ZNHIT1ENSP000003045934STRING: ENSP00000304593
    EAF2ENSP000002736684STRING: ENSP00000273668
    VPS72ENSP000003578874STRING: ENSP00000357887
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0006357regulation of transcription from RNA polymerase II promoter IEA--
    GO:0032784regulation of DNA-templated transcription, elongation IEA--

    Find genes that share ontologies with TCEA3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TCEA3

    2 Novoseek inferred chemical compound relationships for TCEA3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    6-azauracil 86.3 2 12511561 (1), 15780939 (1)
    zinc 24.1 7 1868060 (3), 9724522 (2), 9712887 (1)



    Find genes that share compounds with TCEA3           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TCEA3 gene: 
    NM_003196.1  

    Unigene Cluster for TCEA3:

    Transcription elongation factor A (SII), 3
    Hs.446354  [show with all ESTs]
    Unigene Representative Sequence: NM_003196
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000450454(uc009vqm.2 uc021oig.1 uc021oih.1 uc010ody.1)
    ENST00000476978 ENST00000374601 ENST00000461794 ENST00000374602 ENST00000492271

    miRNA
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    Block miRNA regulation of human, mouse, rat TCEA3 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate TCEA3:
    hsa-miR-515-5p hsa-miR-145 hsa-miR-516a-3p hsa-miR-516b* hsa-miR-450b-5p hsa-miR-766 hsa-miR-519e*
    SwitchGear 3'UTR luciferase reporter plasmidTCEA3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TCEA3
    Predesigned siRNA for gene silencing in human, mouse, rat TCEA3
    Clone
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    GenScript: all cDNA clones in your preferred vector: TCEA3 (NM_003196)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCEA3
    Primer
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    OriGene qPCR primer pairs and template standards for TCEA3
    OriGene qSTAR qPCR primer pairs in human, mouse for TCEA3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TCEA3
      QuantiTect SYBR Green Assays in human, mouse, rat TCEA3
      QuantiFast Probe-based Assays in human, mouse, rat TCEA3

    Additional mRNA sequence: 

    AJ223473.1 AK027024.1 AK290272.1 AK300707.1 AK310039.1 AY540752.1 BC041613.1 

    11 DOTS entries:

    DT.448657  DT.432013  DT.92420864  DT.100780717  DT.91939517  DT.92420863  DT.91667417  DT.91880930 
    DT.91886475  DT.95072939  DT.95199690 

    Selected AceView cDNA sequences (see all 121):

    BE880226 AI669819 CA435035 AI861898 AA688241 AI308948 AI202589 AA970866 
    AJ223473 AI393002 AK027024 AI097019 AA888058 NM_003196 T95597 CA449942 
    AW151718 BG059665 BC041613 AI572481 AA071471 CF127872 AI193651 BQ006295 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TCEA3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACAAGGTGA
    TCEA3 Expression
    About this image


    TCEA3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Heart (Cardiovascular System)
             Cardiomyocyte-like progenitor cells
     
     Epiblast (Early Embryonic Tissues)
             Epiblast Cells Epiblast
     
     Blood (Hematopoietic System)
             T Helper Cells Peripheral Blood
    TCEA3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TCEA3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.446354
        Custom PCR Arrays for TCEA3
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TCEA3 gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tcea31 , 5 transcription elongation factor A (SII), 31, 5 87.96(n)1
    88.73(a)1
      4 (68.34 cM)5
    214011  NM_011542.21  NP_035672.11 
     1362477295 
    chicken
    (Gallus gallus)
    Aves TCEA36
    transcription elongation factor A (SII), 3
    47(a)
    1 ↔ 1
    23(2130236-2135679)
    lizard
    (Anolis carolinensis)
    Reptilia TCEA36
    transcription elongation factor A (SII), 3
    73(a)
    1 ↔ 1
    GL343904.1(59829-71600)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.4082 Xenopus laevis mRNA for transcription elongation factor more 74.15(n)    AB040437.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.156342 Transcribed sequence with moderate similarity to protein more 80.7(n)    BM342366.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta TfIIS1 , 3 RNA elongation from Pol II promoter
    transcription more3
    RNA polymerase II elongation factor1
    62(a)
    (best of 2)3
    56.16(n)1
    50.8(a)1
      348831  NM_057619.41  NP_476967.11 
    worm
    (Caenorhabditis elegans)
    Secernentea T24H10.13 transcription factor S-II 37(a)   II(9099286-9100363)   --
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes DST16
    General transcription elongation factor TFIIS, ena...
    26(a)
    1 → many
    VII(417483-418412) YGL043W


    ENSEMBL Gene Tree for TCEA3 (if available)
    TreeFam Gene Tree for TCEA3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TCEA3 gene
    TCEA12  TCEANC2  TCEA22  
    3 SIMAP similar genes for TCEA3 using alignment to 4 protein entries:     TCEA3_HUMAN (see all proteins):
    TCEA1    TCEA2    TCEANC

    Find genes that share paralogs with TCEA3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TCEA3 (see all 973)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs6515421,2
    C,F,A,H--23707401(-) AGAACA/TGTTGA 1 -- ds500123Minor allele frequency- T:0.17NS EA NA WA CSA 1546
    rs1860544021,2
    --23707429(+) GTGGGA/GGTGGG 1 -- ds50010--------
    rs1133757301,2
    C,F--23707432(+) GGGGTG/CGGGTA 1 -- ds50012Minor allele frequency- C:0.05CSA WA 120
    rs6510361,2
    C,F,H--23707516(-) CAGACC/GTTTGC 1 -- ds500118Minor allele frequency- G:0.19NA NS EA WA CSA 920
    rs31925641,2
    F--23707641(-) cgcttA/Gacccc 1 -- ut311Minor allele frequency- G:0.33MN 184
    rs6501021,2
    C,F--23707692(-) GGTGGC/TTTATG 1 -- ut31 ese312Minor allele frequency- T:0.21MN NA WA CSA EA 556
    rs1388484081,2
    --23707798(+) ATGACC/TGATTA 1 -- ut310--------
    rs1897231041,2
    --23707845(+) ATCCCA/GCTCAG 1 -- ut310--------
    rs786780721,2
    F--23707860(+) AGTTCA/GGTATT 1 -- ut311Minor allele frequency- G:0.01WA 118
    rs1813297161,2
    --23707935(+) CCTCAC/TCTTGT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TCEA3 (23707554 - 23751261 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for TCEA3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2745297CNV Deletion23290073
    esv2661255CNV Deletion23128226
    esv2558689CNV Deletion19546169
    esv2745286CNV Deletion23290073
    nsv512726CNV Insertion21212237
    nsv521882CNV Loss19592680
    esv9540CNV Loss19470904
    dgv28n67CNV Loss20364138

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 604128    OMIM disorders: --


    Find genes that share disorders with TCEA3           About GenesLikeMe

    Genetic Association Database (GAD): TCEA3
    Human Genome Epidemiology (HuGE) Navigator: TCEA3 (3 documents)

    Export disorders for TCEA3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TCEA3 gene, integrated from 10 sources (see all 47):
    (articles sorted by number of sources associating them with TCEA3)
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    1. Identification of novel genes encoding transcription elongation factor TFIIS (TCEA) in vertebrates: conservation of three distinct TFIIS isoforms in frog, mouse, and human. (PubMed id 9790746)1, 2, 3, 9 Labhart P. and Morgan G.T. (Genomics 1998)
    2. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. TCEA3 binds to TGF-beta receptor I and induces Smad-independent, JNK-dependent apoptosis in ovarian cancer cells. (PubMed id 23357533)1 Cha Y....Park K.S. (Cell. Signal. 2013)
    5. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    6. The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS. (PubMed id 20178742)1 Kim J.... Roeder R.G. (Cell 2010)
    7. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    8. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 6920 HGNC: 11615 AceView: TCEA3 Ensembl:ENSG00000204219 euGenes: HUgn6920
    ECgene: TCEA3 H-InvDB: TCEA3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TCEA3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TCEA3 gene:
    Search GeneIP for patents involving TCEA3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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