TCAP Gene
protein-coding GIFtS: 63
GCID: GC17P037818
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|
titin-cap(Previous names: limb girdle muscular dystrophy 2G (autosomal recessive),...)
(Previous symbol: LGMD2G)
| |
Aliases
for TCAP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Titin-Cap1 | | Limb Girdle Muscular Dystrophy 2G (Autosomal Recessive)1 2 | | CMD1N1 2 5 | | Telethonin1 | | LGMD2G1 2 5 | | Titin Cap Protein2 3 | | T-Cap1 | | Titin-Cap (Telethonin)1 | | TELE1 2 | | 19 KDa Sarcomeric Protein2 |
Export aliases for TCAP gene to outside databasesPrevious GC identifers: GC17P037321 GC17P039818 GC17P037730 GC17P038195 GC17P035073 GC17P033615 |
Summaries
for TCAP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TCAP:
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity thatextends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteinsare attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domainsand is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this geneare associated with limb-girdle muscular dystrophy type 2G. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: TELT_HUMAN, O15273Function: Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at thesarcomeric Z-disk
Gene Wiki entry for TCAP (Telethonin)
|
Genomic Views
for TCAP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TCAP gene promoter:
AP-2alpha isoform 3 AP-2alpha isoform 4 AP-2alpha isoform 2 AP-2alpha AP-2alphaA
Other transcription factors
Search SABiosciences Chromatin IP Primers for TCAP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCAP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q12 Ensembl cytogenetic band: 17q12 HGNC cytogenetic band: 17q12TCAP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P037818: view genomic region
(about GC identifiers)
Start:
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37,820,440 bp from pter |
End:
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37,822,808 bp from pter |
Size:
|
2,369 bases |
Orientation:
|
plus strand |
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Proteins
for TCAP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TELT_HUMAN, O15273 (See
protein sequence)Recommended Name: Telethonin Size: 167 amino acids; 19052 Da
Subunit: Interacts with MYOZ1 and MYOZ3. Interacts directly with the N-terminal Ig-like domains of 2 titin (TTN)molecules
Subcellular location: Cytoplasm, myofibril, sarcomere
Miscellaneous: The C-terminal domain appears to be unstructured in solution. It may promote the assembly ofhigher-order TTN complexes
2 PDB 3D structures from  and Proteopedia  for TCAP:1YA5 (3D)
2F8V (3D)
Secondary accessions: Q96L27Explore the universe of human proteins at neXtProt for TCAP: NX_O15273
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15273
TCAP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003664.1
ENSEMBL proteins: ENSP00000312624 ENSP00000462787 Reactome Protein details: O15273
Human Recombinant Protein Products for TCAP:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
TCAP for ontologies About GeneDecksing
TCAP Antibody Products:
Assay Products for TCAP: |
Protein
Domains /
Families
for TCAP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TCAP for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O15273ProtoNet protein and cluster: O15273 |
Function
for TCAP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: TELT_HUMAN, O15273Function: Muscle assembly regulating factor. Mediates the antiparallel assembly of titin (TTN) molecules at thesarcomeric Z-disk Genatlas biochemistry entry for TCAP:titin-cap,telethonin
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
TCAP for ontologies About GeneDecksing
Phenotypes:
3 GenomeRNAi human phenotypes for TCAP:
5 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Tcap):
TCAP for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TCAP (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TCAP
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TCAP (NM_003673) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TCAP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCAP |
|
Pathways & Interactions
for TCAP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Striated Muscle Contraction | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for TCAP
2 
Reactome Pathways for TCAP
TCAP for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TCAP
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/41 Interacting proteins for TCAP (O152731, 2, 3 ENSP000003126244) via UniProtKB, MINT, STRING, and/or I2D (see all 41)About this table
Gene Ontology (GO): 5/19 biological process terms (GO ID links to tree view) (see all 19): About this table
TCAP for ontologies About GeneDecksing
|
Drugs & Compounds
for TCAP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TCAP
Search CenterWatch for drugs/clinical trials and news about TCAP / TELT
|
Transcripts
for TCAP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TCAP gene: NM_003673.3 Unigene Cluster for TCAP: Titin-cap Hs.77628 [show with all ESTs]Unigene Representative Sequence: AK0963282 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000309889(uc002hsh.3) ENST00000578283
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TCAP (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TCAP
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TCAP (NM_003673) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TCAP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCAP |
Additional cDNA sequence: AJ000491.1 AK096328.1 BC012628.1 BC013330.1 5 DOTS entries: DT.75122680 DT.120967942 DT.95192122 DT.120967972 DT.95192119 24/581 AceView cDNA sequences (see all 581): CB105314 F31232 BC025679 AI140550 AI969172 NM_006804 AW731937 BG319526 BM987938 BM768106 BF724450 F36245 AK123364 BM678613 AA809725 AI208683 F15846 AL709938 AW627874 X80198 AJ706657 BM717616 F27695 D38255
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for TCAP About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b |
|---|
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| SP1: | | | | | | | | | | | |
| SP2: | | | | | | | | | | |
ECgene alternative splicing isoforms for TCAP
|
Expression
for TCAP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TCAP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGTAAAAAAA
About this image
See TCAP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TCAP
SOURCE GeneReport for Unigene cluster: Hs.77628
UniProtKB/Swiss-Prot: TELT_HUMAN, O15273Tissue specificity: Heart and skeletal muscle
SABiosciences Custom PCR Arrays for TCAP
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TCAP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TCAP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TCAP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TCAP |
Orthologs
for TCAP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TCAP gene from 2/6 species (see all 6) About this table
ENSEMBL Gene Tree for TCAP (if available)
TreeFam Gene Tree for TCAP (if available) |
Paralogs
for TCAP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TCAP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TCAP (37820440 - 37822808 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for TCAP
3 CNVs: 49854 49855 49853
Human Gene Mutation Database (HGMD): TCAP
Locus Specific Mutation Databases (LSDB): TCAP
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TCAP |
|
Disorders
/ Diseases
for TCAP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TCAP for disorders About GeneDecksing
OMIM gene information: 604488
OMIM disorders: 601954 607487
UniProtKB/Swiss-Prot: TELT_HUMAN, O15273
Defects in TCAP are a cause of familial hypertrophic cardiomyopathy (CMH) [MIM:192600]; also designated FHC orHCM. Familial hypertrophic cardiomyopathy is a hereditary heart disorder characterized by ventricular hypertrophy,which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope,collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- andintrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiacdeath Defects in TCAP are a cause of limb-girdle muscular dystrophy type 2G (LGMD2G) [MIM:601954]. LGMD2G is anautosomal recessive degenerative myopathy characterized by proximal and distal muscle weakness and atrophy in thelimbs, dystrophic changes on muscle biopsy, and absence of telethonin. Cardiac muscle is involved in a subset ofpatients Defects in TCAP are the cause of cardiomyopathy dilated type 1N (CMD1N) [MIM:607487]. Dilated cardiomyopathyis a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heartfailure and arrhythmia. Patients are at risk of premature death
20/23  diseases for TCAP (see all 23): About MalaCardslimb-girdle muscular dystrophy muscular dystrophy limb-girdle muscular dystrophy, type 2g myringitis bullosa hemorrhagica
muscular dystrophy with rimmed vacuoles hypertrophic cardiomyopathy myofibrillar myopathy dilated cardiomyopathy
neuromuscular disease congenital muscular dystrophy urticaria pigmentosa dysferlinopathy
cardiomyopathy urticaria diabetic retinopathy myopathy
paralysis prostate cancer breast cancer ataxia
2 diseases from the University of Copenhagen DISEASES database for TCAP:limb-girdle muscular dystrophy Dilated cardiomyopathy 10/17 Novoseek disease relationships for TCAP gene (see all 17) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| lgmd2g |
98.5 |
23 |
10069710 (4), 11665864 (3), 20233748 (2), 14959561 (1) (see all 9) |
| lgmd2h |
93.8 |
7 |
14959561 (1), 15316618 (1), 10069710 (1), 11665864 (1) |
| lgmd2f |
90.4 |
6 |
10069710 (2), 14959561 (1), 15316618 (1) |
| lgmd2b |
90.2 |
11 |
11665864 (3), 14959561 (1), 15316618 (1), 12379311 (1) (see all 5) |
| lgmd2e |
89.8 |
5 |
14959561 (1), 15316618 (1), 10069710 (1) |
| muscular dystrophy, limb-girdle, autosomal recessive |
89.5 |
2 |
10069710 (2) |
| lgmd2a |
87 |
13 |
10069710 (3), 11665864 (3), 14959561 (1), 15316618 (1) (see all 5) |
| lgmd2i |
85.8 |
5 |
14959561 (1), 15316618 (1), 18645206 (1) |
| lgmd1a |
83.3 |
2 |
15316618 (1) |
| muscular dystrophy limb-girdle |
78.7 |
2 |
15043707 (1), 19679566 (1) |
GeneTests: TCAP
Familial Hypertrophic CardiomyopathyDilated Cardiomyopathy
Genetic Association Database (GAD): TCAP
Human Genome Epidemiology (HuGE) Navigator: TCAP (9 documents)
Export disorders for TCAP gene to outside databases
|
Publications
for TCAP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TCAP gene, integrated from 9 sources (see all 87):
(articles sorted by number of sources associating them with TCAP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Tcap gene mutations in hypertrophic cardiomyopathy and dilated cardiomyopathy. (PubMed id 15582318)1, 2, 4, 9 Hayashi T.... Kimura A. (2004)
- Telethonin, a novel sarcomeric protein of heart and skeletal muscle. (PubMed id 9350988)1, 2, 3, 9 Valle G.... Lanfranchi G. (1997)
- Evidence for a dimeric assembly of two titin/telethonin complexes induced by the telethonin C-terminus. (PubMed id 16713295)1, 2, 9 Pinotsis N....Wilmanns M. (2006)
- Two immunoglobulin-like domains of the Z-disc portion of titin interact in a conformation-dependent way with telethonin. (PubMed id 9645487)1, 2, 9 Mues A.... Gautel M. (1998)
- Deletion of Glu at codon 13 in the TCAP gene encoding the Z-disc protein titin-cap/telethonin is a rare non-synonymous polymorphism. (PubMed id 16490376)1, 2, 9 Perrot A.... Osterziel K.J. (2006)
- Genotype-phenotype relationships involving hypertrophic cardiomyopathy-associated mutations in titin, muscle LIM protein, and telethonin. (PubMed id 16352453)1, 2, 9 Bos J.M.... Ackerman M.J. (2006)
- The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. (PubMed id 12507422)1, 2, 9 Knoell R.... Chien K.R. (2002)
- Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk. (PubMed id 16407954)1, 2, 9 Zou P.... Wilmanns M. (2006)
- Calsarcin-3, a novel skeletal muscle-specific member of the calsarcin family, interacts with multiple Z-disc proteins. (PubMed id 11842093)1, 2, 9 Frey N. and Olson E.N. (2002)
- Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin. (PubMed id 10655062)1, 2, 9 Moreira E.S.... Jenne D.E. (2000)
|
External Searches for TCAP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TCAP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TCAP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TCAP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for TCAP gene:
Search GeneIP for patents involving TCAP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TCAP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for TCAP | | OriGene shRNA RFP for TCAP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TCAP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TCAP | | | OriGene Protein Over-expression Lysate for TCAP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TCAP | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TCAP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TCAP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TCAP | | OriGene Custom Protein Services for TCAP | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TCAP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TCAP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCAP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TCAP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TCAP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TCAP |
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| | | |  |  |  |  | | | | Search ThermoFisher Antibodies for TCAP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCAP |
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