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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TCAM1P Gene

pseudogene   GIFtS: 27
GCID: GC17P061927

testicular cell adhesion molecule 1, pseudogene

(Previous names: testicular cell adhesion molecule 1 homolog (mouse), testicular...)
(Previous symbol: TCAM1)
  Search for TCAM1P
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Biological research products
for TCAM1P    

Aliases
for TCAM1P gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Testicular Cell Adhesion Molecule 1, Pseudogene1 2
TCAM11 2 5
Testicular Cell Adhesion Molecule 1 Homolog (Mouse)1
Testicular Cell Adhesion Molecule 1 Homolog (Mouse), Pseudogene1

External Ids:    HGNC: 307071   Entrez Gene: 1467712   Ensembl: ENSG000002402807   OMIM: 6127565   

Export aliases for TCAM1P gene to outside databases


Summaries
for TCAM1P gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TCAM1P:
This pseudogene is located downstream from the growth hormone locus on chromosome 17. This locus evolved by a series of
partial duplications that have disrupted the human gene. A homologous gene in mouse encodes a testis-specific cell
adhesion protein that may play a role in germ cell-Sertoli cell interactions. (provided by RefSeq, Apr 2012)




Genomic Views
for TCAM1P gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.1  NT_010783.15  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for TCAM1P
         Other transcription factors

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Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TCAM1P


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17q23.3   Ensembl cytogenetic band:  17q23.3   HGNC cytogenetic band: 17q

TCAM1P Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCAM1P gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17P061927:  view genomic region     (about GC identifiers)

Start:
 61,926,652 bp from pter      End:
 61,941,739 bp from pter
Size:
 15,088 bases      Orientation:
 plus strand

Proteins
for TCAM1P gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB: --

Protein Domains /
Families
for TCAM1P gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
   --

Function
for TCAM1P gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
Animal Models:
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miRNA
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Pathways & Interactions
for TCAM1P gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TCAM1P

Drugs & Compounds
for TCAM1P gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
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Search CenterWatch for drugs/clinical trials and news about TCAM1P 

Transcripts
for TCAM1P gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

Unigene Cluster for TCAM1P:

Testicular cell adhesion molecule 1, pseudogene
Hs.629177  [show with all ESTs]
Unigene Representative Sequence: NR_002947
7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000463377 ENST00000469014 ENST00000482005 ENST00000466125 ENST00000478379(uc002jcf.3)
ENST00000485295 ENST00000476374

miRNA
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Inhib. RNA
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Clone
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Additional cDNA sequence: 

AB026156.1 NR_002947.2 

7 DOTS entries:

DT.40260655  DT.423048  DT.40203618  DT.75188898  DT.120927318  DT.120927331  DT.92038493 

GeneLoc Exon Structure


Expression
for TCAM1P gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TCAM1P expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGGGTGTCTA
TCAM1P Expression
About this image

TCAM1P expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

6 LifeMap In Vivo Development Anatomical Compartments/Cells 
Tissue Anatomical Compartment CellCategory (developmental path)
BoneAutopod Long BoneBone
BoneEndochondral Facial BonesBone
BoneStylopod Long BoneBone
BoneThoracic RibBone
BoneZeugopod Long BoneBone
CartilageMeckel's CartilageCartilage
Expression: Positive    Negative     Selective marker
Experimental details: Curated     Microarrays     In-situ hybridization

Genevestigator expression for TCAM1P

SOURCE GeneReport for Unigene cluster: Hs.629177
    SABiosciences Custom PCR Arrays for TCAM1P
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In Situ
Assay Products: 
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Orthologs
for TCAM1P gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
This gene was present in the common ancestor of human and mouse.

Orthologs for TCAM1P gene from 1 species (see representative species )    About this table
Organism Taxonomic
classification		 Gene Description Human
Similarity		 Orthology
Type		 Details
mouse
(Mus musculus)		 Mammalia Tcam15 testicular cell adhesion molecule 1   --   11 (68.89 cM) 106276672 


ENSEMBL Gene Tree for TCAM1P (if available)
TreeFam Gene Tree for TCAM1P (if available) 

Paralogs
for TCAM1P gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

Genomic Variants
for TCAM1P gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/206 NCBI SNPs in TCAM1P are shown (see all 206)     About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance		Chr 17 posSequence#AA
Chg		TypeMore#Allele
freq		PopTotal
sample		More
----------
rs1455561091,2
--61932394(+) ACAGAA/CTCGTT 1 -- us2k10--------
rs169471541,2
C,F,H--61932396(+) AGAATC/TGTTAC 1 -- us2k19Minor allele frequency- T:0.05NA NS EA WA 682
rs1379040381,2
--61932447(+) TATCAC/GAGAGG 1 -- us2k10--------
rs1847950251,2
--61932641(+) ATGACA/GGGAAA 1 -- us2k10--------
rs585319051,2
C--61932751(+) AAGAG-/GACCTG 1 -- us2k10--------
rs26658371,2
C,F,A,H--61932866(-) TAGGCG/ATGAGC 1 -- us2k17Minor allele frequency- A:0.33NA WA CSA 12
rs1459763191,2
--61933103(+) CAAAAA/GGAGTG 1 -- us2k10--------
rs169471571,2
C,F--61933161(+) ATCCAT/CCTGAC 1 -- us2k14Minor allele frequency- C:0.03NA WA 260
rs1901937301,2
--61933162(+) TCCATC/TTGACA 1 -- us2k10--------
rs1819145351,2
--61933190(+) GAAGAG/TTTCCA 1 -- us2k10--------

HapMap Linkage Disequilibrium report for TCAM1P (61926652 - 61941739 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for TCAM1P: --

SABiosciences Cancer Mutation PCR Assays
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Disorders / Diseases
for TCAM1P gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
TCAM1P for disorders           About MalaCards

TCAM1P for disorders           About GeneDecksing

OMIM gene information: 612756    OMIM disorders: --


Export disorders for TCAM1P gene to outside databases

Publications
for TCAM1P gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for TCAM1P gene integrated from 9 sources:
(articles sorted by number of sources associating them with TCAM1P)		    Utopia: connect your pdf to the dynamic
world of online information

  1. Testicular cell adhesion molecule 1 (TCAM1) is not es sential for fertility. (PubMed id 19766163)1, 3 Nalam R.L....Matzuk M.M. (2010)
  2. Structure, expression, and conserved physical linkage of mouse testicular cell adhesion molecule-1 (TCAM-1) gene. (PubMed id 11195349)1, 3 Sakatani S....Ono M. (2000)
  3. The human growth hormone locus: nucleotide sequence, biology, and evolution. (PubMed id 2744760)1, 3 Chen E.Y....Seeburg P.H. (1989)
  4. Identification and analysis of unitary pseudogenes: h istoric and contemporary gene losses in humans and other primates. (PubMed id 20210993)1 Zhang Z.D....Gerstein M. (2010)
  5. Gene structure of rat testicular cell adhesion molecule 1 (TCAM-1), and its physical linkage to genes coding for the growth hormone and BAF60b, a component of SWI/SNF complexes. (PubMed id 9889334)1 Ono M....Nakazato S. (1999)

External Searches for TCAM1P gene

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing TCAM1P gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 146771 HGNC: 30707 Ensembl:ENSG00000240280 euGenes: HUgn146771 ECgene: TCAM1P
H-InvDB: TCAM1P

Other Databases showing TCAM1P gene

(According to HUGE)
About This Section
   --

Specialized Databases showing TCAM1P gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for TCAM1P Pharmacogenomics, SNPs, Pathways

Intellectual Property
for TCAM1P gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for TCAM1P gene:
Search GeneIP for patents involving TCAM1P

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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About This Section

 
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