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TCAIM Gene

protein-coding   GIFtS: 35
GCID: GC03P044379

T Cell Activation Inhibitor, Mitochondrial

(Previous name: chromosome 3 open reading frame 23)
(Previous symbol: C3orf23)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
T Cell Activation Inhibitor, Mitochondrial1 2     TOAG12 3
C3orf231 2 3     Chromosome 3 Open Reading Frame 231
Tolerance Associated Gene-1 Protein2 3     Tolerance Associated Gene-11
TOAG-12 3     T-Cell Activation Inhibitor, Mitochondrial2

External Ids:    HGNC: 252411   Entrez Gene: 2853432   Ensembl: ENSG000001791527   UniProtKB: Q8N3R33   

Export aliases for TCAIM gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TCAIM Gene:
TCAIM (T cell activation inhibitor, mitochondrial) is a protein-coding gene. Diseases associated with TCAIM include malaria.

UniProtKB/Swiss-Prot: TCAIM_HUMAN, Q8N3R3
Function: May regulate T-cell apoptosis (By similarity)

Gene Wiki entry for TCAIM (C3orf23) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_022517.19  NC_018914.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for TCAIM
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTCAIM promoter sequence
   Search Chromatin IP Primers for TCAIM

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TCAIM


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.31   Ensembl cytogenetic band:  3p21.31   HGNC cytogenetic band: 3p21.33-p21.32

TCAIM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TCAIM gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P044379:  view genomic region     (about GC identifiers)

Start:
44,379,611 bp from pter      End:
44,450,943 bp from pter
Size:
71,333 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TCAIM_HUMAN, Q8N3R3 (See protein sequence)
Recommended Name: T-cell activation inhibitor, mitochondrial  
Size: 496 amino acids; 57925 Da
Secondary accessions: A8K9P1 Q0P5T9 Q495R1 Q495R3 Q4G0M4 Q6GMU8
Alternative splicing: 4 isoforms:  Q8N3R3-1   Q8N3R3-2   Q8N3R3-3   Q8N3R3-4   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TCAIM: NX_Q8N3R3

Explore proteomics data for TCAIM at MOPED


See TCAIM Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (6 alternative transcripts): 
NP_001025010.1  NP_001025011.1  NP_001269842.1  NP_001269843.1  NP_001269844.1  NP_776187.2  

ENSEMBL proteins: 
 ENSP00000373252   ENSP00000402581   ENSP00000379388   ENSP00000341539   ENSP00000392032  
 ENSP00000387842   ENSP00000402604  

TCAIM Human Recombinant Protein Products:

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TCAIM Assay Products:

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Browse ELISAs at Cloud-Clone Corp.
Browse CLIAs at Cloud-Clone Corp.


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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3 InterPro protein domains:
 IPR027989 DUF4461
 IPR028031 DUF4460
 IPR027986 TCAIM

Graphical View of Domain Structure for InterPro Entry Q8N3R3

ProtoNet protein and cluster: Q8N3R3


TCAIM for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: TCAIM_HUMAN, Q8N3R3
Function: May regulate T-cell apoptosis (By similarity)

Phenotypes:
     1 GenomeRNAi human phenotype for TCAIM:

 Increased gamma-H2AX phosphory 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TCAIM
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TCAIM
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TCAIM

miRNA
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SwitchGear 3'UTR luciferase reporter plasmidTCAIM 3' UTR sequence
Inhib. RNA
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Predesigned siRNA for gene silencing in human, mouse, rat TCAIM

Gene Editing
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DNA2.0 Custom Protein Engineering Service for TCAIM

Clone
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OriGene clones in human, mouse for TCAIM (see all 17)
OriGene ORF clones in mouse, rat for TCAIM
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript Custom all cDNA clones Services for TCAIM
Sino Biological Human cDNA Clone for TCAIM
DNA2.0 Custom Codon Optimized Gene Synthesis Service for TCAIM
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCAIM

Cell Line
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GenScript Custom overexpressing Cell Line Services for TCAIM
Browse ESI BIO Cell Lines and PureStem Progenitors for TCAIM 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCAIM


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
TCAIM_HUMAN, Q8N3R3: Mitochondrion (By similarity)

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005739mitochondrion IDA--

TCAIM for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TCAIM
Interactions:

    Search GeneGlobe Interaction Network for TCAIM

4 Interacting proteins for TCAIM (Q8N3R33) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
EBF1Q9UH733I2D: score=3 
EBF3Q9H4W63I2D: score=3 
SIN3AQ96ST33I2D: score=2 
MAPK6Q166593I2D: score=1 
About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for TCAIM



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for TCAIM gene (6 alternative transcripts): 
NM_001029839.2  NM_001029840.2  NM_001282913.1  NM_001282914.1  NM_001282915.1  NM_173826.3  

Unigene Cluster for TCAIM:

T cell activation inhibitor, mitochondrial
Hs.55131  [show with all ESTs]
Unigene Representative Sequence: NM_173826
12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000383746(uc003cnb.4) ENST00000417237 ENST00000494638 ENST00000396078(uc003cnc.4)
ENST00000342649(uc010him.3 uc003cnd.4 uc003cne.4) ENST00000462230
ENST00000412611 ENST00000444602 ENST00000431657 ENST00000462612 ENST00000417768
ENST00000469246
miRNA
Products:
     
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Search for qRT-PCR Assays for microRNAs that regulate TCAIM
SwitchGear 3'UTR luciferase reporter plasmidTCAIM 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for TCAIM
Predesigned siRNA for gene silencing in human, mouse, rat TCAIM
Clone
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OriGene clones in human, mouse for TCAIM (see all 17)
OriGene ORF clones in mouse, rat for TCAIM
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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DNA2.0 Custom Codon Optimized Gene Synthesis Service for TCAIM
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCAIM
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for TCAIM
Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TCAIM
  QuantiTect SYBR Green Assays in human, mouse, rat TCAIM
  QuantiFast Probe-based Assays in human, mouse, rat TCAIM

Additional mRNA sequence: 

AK056593.1 AK123680.1 AK124087.1 AK292756.1 AL832473.1 AL833118.1 BC009400.2 BC038420.1 
BC047231.1 BC062587.1 BC073829.1 BC101059.2 BC101060.2 BC101061.2 

13 DOTS entries:

DT.446526  DT.311281  DT.100788702  DT.100788700  DT.70102750  DT.100760498  DT.311282  DT.95139788 
DT.100788699  DT.120905086  DT.95185195  DT.100683400  DT.92062583 

Selected AceView cDNA sequences (see all 202):

BM970568 AI248643 AA639405 R77698 AI215014 CA446446 AA978051 CB132893 
BQ014251 BX381695 AI805653 CB410866 BU189734 BU627231 BC073829 AI830822 
N73056 BF940256 BC047231 CR602485 BC038420 T39891 AA313786 AW149514 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for TCAIM (see all 14)    About this scheme

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d · 10e · 10f ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a ·
SP1:                                      -                 -     -     -           -     -                                   -                                 
SP2:                                      -                 -     -     -           -                                         -                                 
SP3:                                      -                 -     -     -           -     -                                                                     
SP4:                                                        -     -     -           -     -                                   -                                 
SP5:                                      -                 -           -           -                                                                           

ExUns: 15b ^ 16 ^ 17a · 17b
SP1:                        
SP2:                        
SP3:                        
SP4:                        
SP5:                        


ECgene alternative splicing isoforms for TCAIM

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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TCAIM expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
TCAIM Expression
About this image

TCAIM Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

TCAIM Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.55131
    Custom PCR Arrays for TCAIM
Primer
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCAIM

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for TCAIM gene from Selected species (see all 15)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Tcaim1 , 5 DNA segment, Chr 9, ERATO Doi 402, expressed5
T cell activation inhibitor, mitochondrial1
82.53(n)1
82.86(a)1
  9 (73.14 cM)5
3821171  NM_001013405.21  NP_001013423.21 
 1228055395 
chicken
(Gallus gallus)
Aves C2H3ORF231 chromosome 2 open reading frame, human C3orf23 75.32(n)
76.07(a)
  420670  XM_418769.4  XP_418769.2 
lizard
(Anolis carolinensis)
Reptilia TCAIM6
T cell activation inhibitor, mitochondrial
72(a)
1 ↔ 1
1(193281447-193307914)
tropical clawed frog
(Xenopus tropicalis)
Amphibia Str.182282 Transcribed sequence with weak similarity to protein more 76.08(n)    AL971925.2 
zebrafish
(Danio rerio)
Actinopterygii LOC5592581 T-cell activation inhibitor, mitochondrial-like 58.6(n)
58.96(a)
  559258  XM_682578.3  XP_687670.2 
fruit fly
(Drosophila melanogaster)
Insecta CG132951 CG13295 44.25(n)
33.62(a)
  38692  NM_139764.3  NP_648021.1 
worm
(Caenorhabditis elegans)
Secernentea C35B8.31 C35B8.3 41.53(n)
29.23(a)
  181152  NM_001029272.2  NP_001024443.1 


ENSEMBL Gene Tree for TCAIM (if available)
TreeFam Gene Tree for TCAIM (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for TCAIM (see all 1318)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1872236471,2
C--44377646(+) ACTGAA/GGTAGA 1 -- us2k10--------
rs1154814291,2
C,F--44377768(+) AACAGA/GGCTAA 1 -- us2k10--------
rs1465145721,2
--44377943(+) ATTATC/TTGTTG 1 -- us2k10--------
rs117075821,2
C,F,A,H--44377959(+) ccacaA/Gtcaga 3 -- us2k119Minor allele frequency- G:0.31NS EA NA CSA WA 2205
rs1405612611,2
--44377975(+) CCTGGC/GATCAT 3 -- us2k10--------
rs1456416641,2
--44377982(+) TCATCC/TACAGA 3 -- us2k10--------
rs1381819701,2
C--44378106(+) CTCTCA/GCCCTC 3 -- us2k10--------
rs1410001561,2
--44378123(+) ACCCTC/TGTTCT 3 -- us2k10--------
rs1853884171,2
--44378129(+) GTTCTA/GCAGGA 3 -- us2k10--------
rs1899216431,2
--44378199(+) CCCCCC/TCTTCA 3 -- us2k10--------

HapMap Linkage Disequilibrium report for TCAIM (44379611 - 44450943 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for TCAIM: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing TCAIM
DNA2.0 Custom Variant and Variant Library Synthesis for TCAIM

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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1 disease for TCAIM:    
About MalaCards
malaria


TCAIM for disorders           About GeneDecksing


Export disorders for TCAIM gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for TCAIM gene, integrated from 10 sources (see all 17):
(articles sorted by number of sources associating them with TCAIM)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  4. B-cell-related biomarkers of tolerance are up-regulated in rejection-free kidney transplant recipients. (PubMed id 23222918)1 Viklicky O....Reinke P. (Transplantation 2013)
  5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
  6. Expansion of memory-type CD8+ T cells correlates with the failure of early immunosuppression withdrawal after cadaver liver transplantation using high-dose ATG induction and rapamycin. (PubMed id 23799424)1 Donckier V....Goldman M. (Transplantation 2013)
  7. Cutting Edge: Immunological consequences and trafficking of human regulatory macrophages administered to renal transplant recipients. (PubMed id 21804023)1 Hutchinson J.A....FAondrich F. (J. Immunol. 2011)
  8. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
  9. Expression of tolerance associated gene-1, a mitochondrial protein inhibiting T cell activation, can be used to predict response to immune modulating therapies. (PubMed id 19684086)1 Keeren K....Sawitzki B. (J. Immunol. 2009)
  10. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 285343 HGNC: 25241 AceView: DKFZp313N0621 Ensembl:ENSG00000179152 euGenes: HUgn285343
ECgene: TCAIM H-InvDB: TCAIM

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for TCAIM Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for TCAIM gene:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TCAIM  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for TCAIM  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for TCAIM  
 OriGene qSTAR qPCR primer pairs in human, mouse for TCAIM   OriGene Purified Protein for TCAIM  
 OriGene ORF clones in mouse, rat for TCAIM   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for TCAIM   OriGene Custom Protein Services for TCAIM  

 
 
 Block miRNA regulation of human, mouse, rat TCAIM using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TCAIM
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TCAIM Predesigned siRNA for gene silencing in human, mouse, rat TCAIM
 QuantiFast Probe-based Assays in human, mouse, rat TCAIM QuantiTect SYBR Green Assays in human, mouse, rat TCAIM
 Custom PCR Arrays for TCAIM Search Chromatin IP Primers for TCAIM
 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TCAIM Search GeneGlobe Interaction Network for TCAIM
 Search Regulatory tfbs for TCAIM
 GenScript Custom Purified and Recombinant Proteins Services for TCAIM GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for TCAIM
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 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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 Search Tocris compounds for TCAIM
 Browse Sino Biological Proteins
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Biologicals
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 Search for Antibodies for TCAIM at Abcam
 See all of Abcam's Antibodies, Kits and Proteins for TCAIM
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 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
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 Browse ESI BIO Cell Lines and PureStem Progenitors for TCAIM
 Gene Synthesis
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 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TCAIM
 SwitchGear 3'UTR luciferase reporter plasmids for TCAIM
 SwitchGear Promoter luciferase reporter plasmids for TCAIM
 ThermoFisher Antibodies for TCAIM
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TCAIM
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TCAIM
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TCAIM
 Search LSBio for Antibodies for TCAIM
Customized transgenic rodents for:
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GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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