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Aliases for TCAIM Gene

Aliases for TCAIM Gene

  • T Cell Activation Inhibitor, Mitochondrial 2 3
  • Tolerance Associated Gene-1 Protein 3 4
  • C3orf23 3 4
  • TOAG-1 3 4
  • TOAG1 3 4
  • T-Cell Activation Inhibitor, Mitochondrial 3
  • Chromosome 3 Open Reading Frame 23 2
  • Tolerance Associated Gene-1 2

External Ids for TCAIM Gene

Previous Symbols for TCAIM Gene

  • C3orf23

Summaries for TCAIM Gene

GeneCards Summary for TCAIM Gene

TCAIM (T Cell Activation Inhibitor, Mitochondrial) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TCAIM Gene

  • May regulate T-cell apoptosis.

Gene Wiki entry for TCAIM Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TCAIM Gene

Genomics for TCAIM Gene

Genomic Location for TCAIM Gene

Start:
44,338,119 bp from pter
End:
44,409,451 bp from pter
Size:
71,333 bases
Orientation:
Plus strand

Genomic View for TCAIM Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TCAIM Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TCAIM Gene

No data available for Regulatory Elements for TCAIM Gene

Proteins for TCAIM Gene

  • Protein details for TCAIM Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N3R3-TCAIM_HUMAN
    Recommended name:
    T-cell activation inhibitor, mitochondrial
    Protein Accession:
    Q8N3R3
    Secondary Accessions:
    • A8K9P1
    • Q0P5T9
    • Q495R1
    • Q495R3
    • Q4G0M4
    • Q6GMU8

    Protein attributes for TCAIM Gene

    Size:
    496 amino acids
    Molecular mass:
    57925 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TCAIM Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TCAIM Gene

Proteomics data for TCAIM Gene at MOPED

Post-translational modifications for TCAIM Gene

No Post-translational modifications

No data available for DME Specific Peptides for TCAIM Gene

Domains for TCAIM Gene

Protein Domains for TCAIM Gene

InterPro:
ProtoNet:
genes like me logo Genes that share domains with TCAIM: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TCAIM Gene

Function for TCAIM Gene

Molecular function for TCAIM Gene

UniProtKB/Swiss-Prot Function: May regulate T-cell apoptosis.

Phenotypes for TCAIM Gene

GenomeRNAi human phenotypes for TCAIM:
genes like me logo Genes that share phenotypes with TCAIM: view

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TCAIM Gene

Localization for TCAIM Gene

Subcellular locations from UniProtKB/Swiss-Prot for TCAIM Gene

Mitochondrion.

Gene Ontology (GO) - Cellular Components for TCAIM Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IDA --
genes like me logo Genes that share ontologies with TCAIM: view

Pathways for TCAIM Gene

SuperPathways for TCAIM Gene

No Data Available

Interacting Proteins for TCAIM Gene

Selected Interacting proteins: Q8N3R3-TCAIM_HUMAN for TCAIM Gene via I2D

Gene Ontology (GO) - Biological Process for TCAIM Gene

None

No data available for Pathways by source for TCAIM Gene

Transcripts for TCAIM Gene

Unigene Clusters for TCAIM Gene

T cell activation inhibitor, mitochondrial:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TCAIM Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b · 10c · 10d · 10e · 10f ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a ·
SP1: - - - - - - -
SP2: - - - - - -
SP3: - - - - - -
SP4: - - - - - -
SP5: - - - -
SP6: - - - - - - - - - -
SP7: - - - - - - - - -
SP8: - - - -
SP9: - - - - -
SP10: - - - - - - - - - -
SP11: - - - - - - - - - -
SP12: - - - - - - - - - - -
SP13: -
SP14: -

ExUns: 15b ^ 16 ^ 17a · 17b
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:

Relevant External Links for TCAIM Gene

GeneLoc Exon Structure for
TCAIM
ECgene alternative splicing isoforms for
TCAIM

Expression for TCAIM Gene

mRNA expression in normal human tissues for TCAIM Gene

SOURCE GeneReport for Unigene cluster for TCAIM Gene Hs.55131

genes like me logo Genes that share expressions with TCAIM: view

Orthologs for TCAIM Gene

This gene was present in the common ancestor of animals.

Orthologs for TCAIM Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TCAIM 36
  • 99.66 (n)
  • 99.4 (a)
TCAIM 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TCAIM 36
  • 89.81 (n)
  • 89.06 (a)
TCAIM 37
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TCAIM 36
  • 92.14 (n)
  • 93.75 (a)
TCAIM 37
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tcaim 36
  • 82.53 (n)
  • 82.86 (a)
Tcaim 16
Tcaim 37
  • 81 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TCAIM 37
  • 73 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TCAIM 37
  • 76 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tcaim 36
  • 83 (n)
  • 84.41 (a)
chicken
(Gallus gallus)
Aves C2H3ORF23 36
  • 75.32 (n)
  • 76.07 (a)
TCAIM 37
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TCAIM 37
  • 72 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.18228 36
tcaim 36
  • 67.9 (n)
  • 66.19 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC559258 36
  • 58.6 (n)
  • 58.96 (a)
TCAIM 37
  • 55 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009133 36
  • 41.08 (n)
  • 29.82 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13295 36
  • 44.25 (n)
  • 33.62 (a)
CG13295 37
  • 31 (a)
OneToMany
CG2854 37
  • 23 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea C35B8.3 36
  • 41.53 (n)
  • 29.23 (a)
C35B8.3 37
  • 24 (a)
OneToOne
Species with no ortholog for TCAIM:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TCAIM Gene

ENSEMBL:
Gene Tree for TCAIM (if available)
TreeFam:
Gene Tree for TCAIM (if available)

Paralogs for TCAIM Gene

No data available for Paralogs for TCAIM Gene

Variants for TCAIM Gene

Sequence variations from dbSNP and Humsavar for TCAIM Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs13575 -- 44,359,763(-) AGAAT(A/C/G)GAGAT utr-variant-3-prime, intron-variant
rs936944 -- 44,344,322(+) CTTCT(A/G)AAATG intron-variant
rs1982814 -- 44,342,999(+) gggtg(C/T)ggtgg intron-variant
rs2279454 -- 44,338,372(+) GCAGT(C/T)ACCAG upstream-variant-2KB, intron-variant
rs2372687 -- 44,343,284(+) ataca(A/G)atctc intron-variant

Relevant External Links for TCAIM Gene

HapMap Linkage Disequilibrium report
TCAIM

No data available for Structural Variations from Database of Genomic Variants (DGV) for TCAIM Gene

Disorders for TCAIM Gene

No disorders were found for TCAIM Gene.

No data available for UniProtKB/Swiss-Prot for TCAIM Gene

Publications for TCAIM Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  4. Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation. (PMID: 15146197) Brandenberger R. … Stanton L.W. (Nat. Biotechnol. 2004) 3
  5. DNA cloning using in vitro site-specific recombination. (PMID: 11076863) Hartley J.L. … Brasch M.A. (Genome Res. 2000) 3

Products for TCAIM Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate TCAIM
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TCAIM
    • Block miRNA regulation of TCAIM using miScript Target Protectors

    Sources for TCAIM Gene

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