Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TC2N Gene

protein-coding   GIFtS: 50
GCID: GC14M092246

Tandem C2 Domains, Nuclear

(Previous names: chromosome 14 open reading frame 47, membrane targeting...)
(Previous symbols: C14orf47, MTAC2D1)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Tandem C2 Domains, Nuclear1 2     Tac2-N2 3
C14orf471 2 3     Chromosome 14 Open Reading Frame 471
MTAC2D11 2 3     C2CD12
Membrane Targeting (Tandem) C2 Domain Containing 11 2     Tandem C2 Domains Nuclear Protein2
C2 Calcium-Dependent Domain Containing 11 2     Membrane Targeting Tandem C2 Domain-Containing Protein 13
Tandem C2 Protein In Nucleus2 3     

External Ids:    HGNC: 198591   Entrez Gene: 1230362   Ensembl: ENSG000001659297   UniProtKB: Q8N9U03   

Export aliases for TC2N gene to outside databases

Previous GC identifers: GC14M091317 GC14M072426


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TC2N Gene:
TC2N (tandem C2 domains, nuclear) is a protein-coding gene.

Gene Wiki entry for TC2N Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  NT_187598.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the TC2N gene promoter:
         STAT5B   STAT1   AML1a   Pbx1a   C/EBPalpha   Gfi-1   POU2F1   FOXO4   POU2F1a   HSF2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTC2N promoter sequence
   Search Chromatin IP Primers for TC2N

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TC2N


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.12   Ensembl cytogenetic band:  14q32.12   HGNC cytogenetic band: 14q32.12

TC2N Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TC2N gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M092246:  view genomic region     (about GC identifiers)

Start:
92,246,095 bp from pter      End:
92,333,880 bp from pter
Size:
87,786 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TAC2N_HUMAN, Q8N9U0 (See protein sequence)
Recommended Name: Tandem C2 domains nuclear protein  
Size: 490 amino acids; 55284 Da
Alternative splicing: 2 isoforms:  Q8N9U0-1   Q8N9U0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TC2N: NX_Q8N9U0

Explore proteomics data for TC2N at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TC2N Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001122067.1  NP_001122068.1  NP_001276063.1  NP_689545.1  

    ENSEMBL proteins: 
     ENSP00000387882   ENSP00000343199   ENSP00000353802   ENSP00000451317   ENSP00000450922  

    TC2N Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for TC2N
    OriGene Protein Over-expression Lysate for TC2N
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TC2N
    GenScript Custom Purified and Recombinant Proteins Services for TC2N
    Novus Biologicals TC2N Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TC2N

     
    Search eBioscience for Proteins for TC2N 

     
    antibodies-online proteins for TC2N (2 products) 

     
    antibodies-online peptides for TC2N

    TC2N Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TC2N
    Novus Biologicals TC2N Antibodies
    Abcam antibodies for TC2N
    Cloud-Clone Corp. Antibodies for TC2N
    ThermoFisher Antibodies for TC2N
    antibodies-online antibodies for TC2N (15 products) 

    TC2N Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TC2N
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TC2N
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TC2N
    Cloud-Clone Corp. CLIAs for TC2N
    Search eBioscience for ELISAs for TC2N 
    antibodies-online kits for TC2N (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR000008 C2_dom

    Graphical View of Domain Structure for InterPro Entry Q8N9U0

    ProtoNet protein and cluster: Q8N9U0

    1 Blocks protein domain: IPB000008 C2 domain

    UniProtKB/Swiss-Prot: TAC2N_HUMAN, Q8N9U0
    Similarity: Contains 1 C2 domain


    Find genes that share domains with TC2N           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with TC2N           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TC2N:
     Increased S DNA content 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TC2N

    miRNA
    Products:
        
    miRTarBase miRNAs that target TC2N:
    hsa-mir-9-5p (MIRT021482)

    Block miRNA regulation of human, mouse, rat TC2N using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TC2N (see all 20):
    hsa-miR-320a hsa-miR-520d-5p hsa-miR-605 hsa-miR-4263 hsa-miR-651 hsa-miR-412 hsa-miR-205 hsa-miR-576-5p
    SwitchGear 3'UTR luciferase reporter plasmidTC2N 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TC2N
    Predesigned siRNA for gene silencing in human, mouse, rat TC2N

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TC2N

    Clone
    Products:
         
    OriGene clones in human, mouse for TC2N (see all 18)
    OriGene ORF clones in mouse, rat for TC2N
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): TC2N (NM_152332)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TC2N
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TC2N

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TC2N
    Browse ESI BIO Cell Lines and PureStem Progenitors for TC2N 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TC2N


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TAC2N_HUMAN, Q8N9U0: Nucleus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    Find genes that share ontologies with TC2N           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TC2N
    Interactions:

        Search GeneGlobe Interaction Network for TC2N

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for TC2N (ENSP000003431994) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TC2N (TAC2N)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TC2N gene (4 alternative transcripts): 
    NM_001128595.2  NM_001128596.2  NM_001289134.1  NM_152332.5  

    Unigene Cluster for TC2N:

    Tandem C2 domains, nuclear
    Hs.510262  [show with all ESTs]
    Unigene Representative Sequence: NM_152332
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000435962(uc001xzu.4 uc010auc.3 uc001xzv.4) ENST00000340892(uc001xzt.4)
    ENST00000360594 ENST00000556018 ENST00000556590 ENST00000554424 ENST00000555302

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TC2N using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TC2N (see all 20):
    hsa-miR-320a hsa-miR-520d-5p hsa-miR-605 hsa-miR-4263 hsa-miR-651 hsa-miR-412 hsa-miR-205 hsa-miR-576-5p
    SwitchGear 3'UTR luciferase reporter plasmidTC2N 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TC2N
    Predesigned siRNA for gene silencing in human, mouse, rat TC2N
    Clone
    Products:
         
    OriGene clones in human, mouse for TC2N (see all 18)
    OriGene ORF clones in mouse, rat for TC2N
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): TC2N (NM_152332)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TC2N
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TC2N
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TC2N
    OriGene qSTAR qPCR primer pairs in human, mouse for TC2N
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TC2N
      QuantiTect SYBR Green Assays in human, mouse, rat TC2N
      QuantiFast Probe-based Assays in human, mouse, rat TC2N

    Additional mRNA sequence: 

    AK093876.1 AK126359.1 BC040503.1 BX647828.1 BX648227.1 

    6 DOTS entries:

    DT.312954  DT.100775358  DT.101982736  DT.100775360  DT.40202222  DT.99973345 

    Selected AceView cDNA sequences (see all 168):

    AW294294 AA578758 BM021374 AA588755 BF430947 AA314397 AI351894 AI151308 
    CF528740 AI470643 AA360896 BX498074 BU676496 AI148628 BE302146 BE928672 
    AA361684 AA075405 AA456598 T56838 AI910436 NM_024764 BM840272 AI741162 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TC2N (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8 ^ 9 ^ 10a · 10b · 10c ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15a · 15b · 15c · 15d
    SP1:              -     -     -     -                       -                                                           -                                 
    SP2:                                -                       -                                                           -                                 
    SP3:                                                        -                                                           -                                 
    SP4:                                -                       -                                               -           -                                 
    SP5:                                                        -                       -                                                                     


    ECgene alternative splicing isoforms for TC2N

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TC2N expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TC2N Expression
    About this image


    TC2N expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Pancreas (Endocrine System)
             Duct Cells Pancreatic Ducts
     
     Epithelial Cells
             Duct Cells Pancreatic Ducts
     
     Fibroblasts
             Dermal Fibroblasts Dorsal Dermis
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Dermis (Integumentary System)
             Dermal Fibroblasts Dorsal Dermis
    TC2N Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TC2N Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.510262
        Custom PCR Arrays for TC2N
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TC2N
    OriGene qSTAR qPCR primer pairs in human, mouse for TC2N
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TC2N
    QuantiTect SYBR Green Assays in human, mouse, rat TC2N
    QuantiFast Probe-based Assays in human, mouse, rat TC2N
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TC2N

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for TC2N gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tc2n1 , 5 tandem C2 domains, nuclear1, 5 88.82(n)1
    87.73(a)1
      12 (51.26 cM)5
    744131  NM_001286364.11  NP_001273293.11 
     1016454435 
    chicken
    (Gallus gallus)
    Aves TC2N1 tandem C2 domains, nuclear 70.82(n)
    68.3(a)
      423412  XM_004941871.1  XP_004941928.1 
    lizard
    (Anolis carolinensis)
    Reptilia TC2N6
    tandem C2 domains, nuclear
    64(a)
    1 ↔ 1
    1(11807795-11869240)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ060997.12   -- 74.44(n)    BJ060997.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1018857221 tandem C2 domains nuclear protein-like 52.79(n)
    47.64(a)
      101885722  XM_005156960.1  XP_005157017.1 


    ENSEMBL Gene Tree for TC2N (if available)
    TreeFam Gene Tree for TC2N (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TC2N gene

    Find genes that share paralogs with TC2N           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for TC2N
    PGOHUM00000237234 PGOHUM00000237291


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TC2N (see all 1626)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs612375051,2
    C--73235379(+) ACCTTG/CTGATC 2 -- ds50011Minor allele frequency- C:0.50NA 2
    rs128821791,2
    C--73235397(+) CTCGGC/TCTCCC 2 -- ds50017Minor allele frequency- T:0.00NA WA CSA 12
    rs128821971,2
    C,F,A,H--73235431(+) agccaT/Ccgtac 2 -- ds500110Minor allele frequency- C:0.01NS EA NA 1138
    rs1887054931,2
    --73235533(+) AATCAC/TATTTT 2 -- ds50010--------
    rs71436571,2
    C--73235561(+) TAAAAA/CTAAAA 2 -- ds50018Minor allele frequency- C:0.06WA NA CSA EA 248
    rs1907735641,2
    --73235838(+) ACCAAA/GATAAC 2 -- ut310--------
    rs171275551,2
    C,F,H--73236020(+) GGAAAA/TTGTTA 2 -- ut3110Minor allele frequency- T:0.05NA NS EA WA 682
    rs1388364681,2
    --73236130(+) CCACAA/GTTATA 2 -- ut310--------
    rs1385592891,2
    --73236196(+) CTGAT-/ATACTT 2 -- ut310--------
    rs1419456091,2
    --73236382(+) CCATGG/TTTTCC 2 -- ut310--------

    HapMap Linkage Disequilibrium report for TC2N (92246095 - 92333880 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TC2N:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv272067CNV Insertion20981092

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing TC2N
    DNA2.0 Custom Variant and Variant Library Synthesis for TC2N

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus

    Find genes that share disorders with TC2N           About GenesLikeMe

    Genetic Association Database (GAD): TC2N
    Human Genome Epidemiology (HuGE) Navigator: TC2N (1 document)

    Export disorders for TC2N gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TC2N gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with TC2N)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Tac2-N, an atypical C-type tandem C2 protein localized in the nucleus. (PubMed id 11526914)1, 3 Fukuda M. and Mikoshiba K. (FEBS Lett. 2001)
    4. Impact on venous thrombosis risk of newly discovered gene variants associated with FVIII and VWF plasma levels. (PubMed id 21029358)1 Morange P.E....TrAcgouAt D.A. (J. Thromb. Haemost. 2011)
    5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    6. Phosphoproteome of resting human platelets. (PubMed id 18088087)2 Zahedi R.P.... Sickmann A. (J. Proteome Res. 2008)
    7. The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (Nucleic Acids Res. 2006)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    9. From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (Genome Res. 2004)
    10. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)2 Heilig R.... Weissenbach J. (Nature 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 123036 HGNC: 19859 AceView: MTAC2D1 Ensembl:ENSG00000165929 euGenes: HUgn123036
    ECgene: TC2N H-InvDB: TC2N

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TC2N Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TC2N gene:
    Search GeneIP for patents involving TC2N

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TC2N  
     OriGene qPCR primer pairs and template standards for TC2N   OriGene Protein Over-expression Lysate for TC2N  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TC2N  
     OriGene qSTAR qPCR primer pairs in human, mouse for TC2N   OriGene Purified Protein for TC2N  
     OriGene ORF clones in mouse, rat for TC2N   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TC2N   OriGene Custom Protein Services for TC2N  

     
     
     Block miRNA regulation of human, mouse, rat TC2N using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TC2N
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TC2N Predesigned siRNA for gene silencing in human, mouse, rat TC2N
     QuantiFast Probe-based Assays in human, mouse, rat TC2N QuantiTect SYBR Green Assays in human, mouse, rat TC2N
     Custom PCR Arrays for TC2N Search Chromatin IP Primers for TC2N
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TC2N  Search GeneGlobe Interaction Network for TC2N
     Regulatory tfbs in TC2N promoter
     GenScript Custom Purified and Recombinant Proteins Services for TC2N GenScript cDNA clones with any tag delivered in your preferred vector for TC2N
     GenScript Custom Assay Services for TC2N GenScript Custom overexpressing Cell Line Services for TC2N
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TC2N (TAC2N)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TC2N antibodies
     TC2N lysates
     Antibodies for TC2N
     See all of Abcam's Antibodies, Kits and Proteins for TC2N
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TC2N
     Antibodies for TC2N
     ELISAs for TC2N
     CLIAs for TC2N



     Browse ESI BIO Cell Lines and PureStem Progenitors for TC2N
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TC2N
     SwitchGear 3'UTR luciferase reporter plasmids for TC2N
     SwitchGear Promoter luciferase reporter plasmids for TC2N
     ThermoFisher Antibodies for TC2N
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TC2N
     Browse compounds at ApexBio
     Search Addgene for plasmids for TC2N
      Search eBioscience for proteins for TC2N
      Search eBioscience for elisas for TC2N
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for TC2N
     antibodies-online antibodies for TC2N (15 products)
     antibodies-online kits for TC2N (4 products)
     antibodies-online peptides for TC2N
     antibodies-online proteins for TC2N (2 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TC2N gene at Home site.
    Version: 3.12.250 16 Nov 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4