Aliases for TBX18 Gene
External Ids for TBX18 Gene
- HGNC: 11595
- Entrez Gene: 9096
- Ensembl: ENSG00000112837
- OMIM: 604613
- UniProtKB: O95935
Previous GeneCards Identifiers for TBX18 Gene
- GC06U990171
- GC06M085413
- GC06M085393
- GC06M085453
- GC06M085500
- GC06M082667
- GC06M085398
- GC06M085444
- GC06M085400
Summaries for TBX18 Gene
-
This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012]
GeneCards Summary for TBX18 Gene
TBX18 (T-Box 18) is a Protein Coding gene. Diseases associated with TBX18 include Pelviureteric Junction Obstruction and Huntington Disease. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is TBX20.
UniProtKB/Swiss-Prot for TBX18 Gene
-
Acts as transcriptional repressor involved in developmental processes of a variety of tissues and organs, including the heart and coronary vessels, the ureter and the vertebral column. Required for embryonic development of the sino atrial node (SAN) head area.
No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TBX18 Gene
Genomics for TBX18 Gene
Regulatory Elements for TBX18 Gene
Enhancers for TBX18 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around TBX18 on UCSC Golden Path with GeneCards custom track
Promoters for TBX18 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around TBX18 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the TBX18 gene promoter:
Regulatory Element Products
Genomic Location for TBX18 Gene
- Chromosome:
- 6
- Start:
- 84,687,351 bp from pter
- End:
- 84,764,730 bp from pter
- Size:
- 77,380 bases
- Orientation:
- Minus strand
Genomic View for TBX18 Gene
Genes around TBX18 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 6q14.3 by Ensembl
- 6q14-q15 by Entrez Gene
- 6q14.1-q15 by HGNC
TBX18 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for TBX18 Gene
Proteins for TBX18 Gene
-
Protein details for TBX18 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- O95935-TBX18_HUMAN
- Recommended name:
- T-box transcription factor TBX18
- Protein Accession:
- O95935
- A2RU13
- Q7Z6U4
- Q9UJI6
Protein attributes for TBX18 Gene
- Size:
- 607 amino acids
- Molecular mass:
- 64753 Da
- Quaternary structure:
-
- Homodimer. Can form a heterodimer with TBX15. Interacts with GATA4 AND NKX2-5. Interacts with PAX3 (By similarity). Interacts (via engrailed homology 1 repressor motif) with TLE3; this interaction represses TBX18 transcriptional activity (By similarity) (PubMed:26235987). Interacts with SIX1 (PubMed:26235987).
Protein Expression for TBX18 Gene
Post-translational modifications for TBX18 Gene
Other Protein References for TBX18 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- R&D Systems Antibodies for TBX18 (TBX18)
- Novus Biologicals Antibodies for TBX18
- Abcam antibodies for TBX18
- Invitrogen Antibodies for TBX18
- antibodies-online Antibodies for TBX18: See all 50
- Search GeneTex for Antibodies for TBX18
-
Santa Cruz Biotechnology (SCBT) Antibodies for TBX18
Protein Products
-
OriGene Purified Proteins for TBX18
- Search Origene for MassSpec and Protein Over-expression Lysates for TBX18
- Origene Custom Protein Services for TBX18
- antibodies-online Proteins for TBX18: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for TBX18
Assay Products
- antibodies-online Kits for TBX18: See all 1
No data available for DME Specific Peptides for TBX18 Gene
Domains & Families for TBX18 Gene
Gene Families for TBX18 Gene
- HGNC:
Protein Domains for TBX18 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for TBX18 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
O95935- Domain:
-
- Contains 1 T-box DNA-binding domain.
Function for TBX18 Gene
Molecular function for TBX18 Gene
- GENATLAS Biochemistry:
- murine T-box gene Tbx18 (T,brachyury) homolog
- UniProtKB/Swiss-Prot Function:
- Acts as transcriptional repressor involved in developmental processes of a variety of tissues and organs, including the heart and coronary vessels, the ureter and the vertebral column. Required for embryonic development of the sino atrial node (SAN) head area.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 26235987 |
| GO:0046982 | protein heterodimerization activity | ISS | -- |
Phenotypes for TBX18 Gene
- MGI mutant phenotypes for TBX18:
-
inferred from 11 alleles
- cellular phenotype
- mortality/aging
- cardiovascular system phenotype
- integument phenotype
- growth/size/body region phenotype
- respiratory system phenotype
- embryo phenotype
- nervous system phenotype
- muscle phenotype
- skeleton phenotype
- renal/urinary system phenotype
- craniofacial phenotype
- no phenotypic analysis
- GenomeRNAi human phenotypes for TBX18:
Animal Models for TBX18 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for TBX18 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TBX18 gene
- Search ViGene Biosciences for TBX18
CRISPR Products
-
OriGene CRISPR knockouts for TBX18
-
Santa Cruz Biotechnology (SCBT) CRISPR for TBX18
- GenScript: Design CRISPR guide RNA sequences for TBX18
miRNA for TBX18 Gene
- miRTarBase miRNAs that target TBX18
-
- hsa-mir-1226-3p (MIRT036442)
- hsa-mir-1206 (MIRT441835)
- hsa-mir-6807-5p (MIRT441836)
- hsa-mir-6516-3p (MIRT441837)
- hsa-mir-376a-2-5p (MIRT441838)
- hsa-mir-3935 (MIRT441839)
- hsa-mir-95-5p (MIRT441840)
- hsa-mir-3668 (MIRT441842)
- hsa-mir-3149 (MIRT445897)
- hsa-mir-653-5p (MIRT445898)
- hsa-mir-568 (MIRT445899)
- hsa-mir-5585-3p (MIRT445900)
- hsa-mir-8068 (MIRT445901)
- hsa-mir-1267 (MIRT445902)
- hsa-mir-33a-3p (MIRT445903)
- hsa-mir-1277-5p (MIRT445904)
- hsa-mir-190a-3p (MIRT520783)
- hsa-mir-101-3p (MIRT520784)
- hsa-mir-5011-5p (MIRT520785)
- hsa-mir-144-3p (MIRT520786)
- hsa-mir-449b-3p (MIRT553718)
- hsa-mir-2681-5p (MIRT553719)
- hsa-mir-5591-3p (MIRT553720)
- hsa-mir-4775 (MIRT553721)
- hsa-mir-4524a-3p (MIRT553722)
- hsa-mir-4735-5p (MIRT553723)
- hsa-mir-4329 (MIRT553724)
- hsa-mir-646 (MIRT553725)
- hsa-mir-590-3p (MIRT553726)
- hsa-mir-4422 (MIRT553727)
- hsa-mir-6835-3p (MIRT553728)
- hsa-mir-6505-5p (MIRT713700)
- hsa-mir-6758-3p (MIRT713701)
miRNA Products
- Search ViGene Biosciences for TBX18
Clone Products
- OriGene clones in human for TBX18
- OriGene ORF clones in human,mouse,rat for TBX18
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for TBX18 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for TBX18 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for TBX18 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for TBX18 Gene
Localization for TBX18 Gene
Subcellular locations from UniProtKB/Swiss-Prot for TBX18 Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 3 |
| golgi apparatus | 2 |
| extracellular | 1 |
No data available for Gene Ontology (GO) - Cellular Components for TBX18 Gene
Pathways & Interactions for TBX18 Gene
More details on SuperPathways for TBX18
No Data Available
Interacting Proteins for TBX18 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0060829 | negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation | ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for TBX18 Gene
Transcripts for TBX18 Gene
mRNA/cDNA for TBX18 Gene
- (5) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (11) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for TBX18 Gene
- T-box 18:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for TBX18
-
Santa Cruz Biotechnology (SCBT) CRISPR for TBX18
- GenScript: Design CRISPR guide RNA sequences for TBX18
miRNA Products
- Search ViGene Biosciences for TBX18
Clone Products
- OriGene clones in human for TBX18
- OriGene ORF clones in human,mouse,rat for TBX18
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
Flow Cytometry Products
Expression for TBX18 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Heart (Cardiovascular System)
- Atrioventricular Valve Cells Atrioventricular Valves
- Epicardial Progenitors Cells Epicardium
- Proepicardial Progenitor cells Proepicardium
- Cardiac Fibroblasts Myocardium
- Vascular Smooth Muscle Cells Coronary Capillary Plexus
-
Somite (Muscoskeletal System)
- Somite Epithelial Cells Sacral Somite
- Somite Epithelial Cells Lumbar Somite
- Presegmented Somitic Mesenchyme Cells Presomitic Mesoderm
- Somite Epithelial Cells Thoracic Somite
- Somite Epithelial Cells Cervical Somite
-
Kidney (Urinary System)
- Ureteric Bud Cells Ureteric Bud
- Metanephric Mesenchyme Cells Metanephric Mesenchyme
-
Mesoderm (Gastrulation Derivatives)
- Septum Transversum Mesenchyme Cells Septum Transversum
- Septum Transversum
-
Smooth Muscle (Muscoskeletal System)
- Vascular Smooth Muscle Cells Coronary Capillary Plexus
- Vascular Smooth Muscle Cells Coronary Vessels
-
Limb (Muscoskeletal System)
- Mesenchymal Condensate Cells Zeugopod
- Autopod
- Blood (Hematopoietic System)
- Mesenchymal Stem Cells
- Umbilical Cord (Extraembryonic Tissues)
-
Paraxial Mesoderm (Gastrulation Derivatives)
- Presegmented Somitic Mesenchyme Cells Presomitic Mesoderm
-
Brain (Nervous System)
- Mature Endothelial Cells Blood Brain Barrier
-
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Blood Brain Barrier
-
Lateral Plate Mesoderm (Gastrulation Derivatives)
- Proepicardial Progenitor cells Proepicardium
-
Fibroblasts
- Cardiac Fibroblasts Myocardium
-
Bone (Muscoskeletal System)
- Mesenchymal Condensate Cells Zeugopod
-
Cartilage (Muscoskeletal System)
- Mesenchymal Condensate Cells Zeugopod
- Eye (Sensory Organs)
mRNA differential expression in normal tissues according to GTEx for TBX18 Gene
This gene is overexpressed in Artery - Tibial (x10.7), Artery - Coronary (x7.2), and Artery - Aorta (x4.8).
This gene is overexpressed in Heart (53.0) and Lung (16.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for TBX18 Gene
SOURCE GeneReport for Unigene cluster for TBX18 Gene Hs.251830
- Elite partner
Primer Products
-
OriGene qPCR primer pairs for TBX18
No data available for mRNA Expression by UniProt/SwissProt for TBX18 Gene
Orthologs for TBX18 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | TBX18 35 |
|
||
| TBX18 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | TBX18 35 |
|
||
| TBX18 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Tbx18 35 |
|
||
| Tbx18 16 |
|
||||
| Tbx18 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | TBX18 35 |
|
||
| TBX18 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Tbx18 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | TBX18 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | TBX18 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | TBX18 35 |
|
||
| TBX18 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | TBX18 36 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | tbx18 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | tbx18 35 |
|
||
| tbx18 35 |
|
||||
| tbx18 36 |
|
OneToOne | |||
| worm (Caenorhabditis elegans) |
Secernentea | mls-1 36 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
OneToMany |
- Species with no ortholog for TBX18:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for TBX18 Gene
Paralogs for TBX18 Gene
(15) SIMAP similar genes for TBX18 Gene using alignment to 5 proteins:
Variants for TBX18 Gene
| SNP ID | Clin | Chr 06 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs172562 | - | 84,764,040(+) | ggccc(C/T)cgccg | reference, missense | |
| VAR_074629 | Congenital anomalies of kidney and urinary tract 2 (CAKUT2) | ||||
| VAR_074630 | - | ||||
| VAR_074631 | Congenital anomalies of kidney and urinary tract 2 (CAKUT2) | ||||
| VAR_074632 | - |
Residual Variation Intolerance Score:
65.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
10.75;
91.59% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for TBX18 Gene
- Human Gene Mutation Database (HGMD)
- TBX18
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TBX18 Gene
Disorders for TBX18 Gene
(6) MalaCards diseases for TBX18 Gene - From: OMIM, ClinVar, Orphanet, Swiss-Prot, DISEASES, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| pelviureteric junction obstruction |
|
|
| huntington disease |
|
|
| congenital hydronephrosis |
|
|
| posterior urethral valves |
|
|
| congenital anomalies of kidney and urinary tract |
|
|
Search TBX18 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
TBX18_HUMAN- Congenital anomalies of kidney and urinary tract 2 (CAKUT2) [MIM:143400]: A disorder encompassing a broad spectrum of renal and urinary tract malformations that include renal agenesis, kidney hypodysplasia, multicystic kidney dysplasia, duplex collecting system, posterior urethral valves and ureter abnormalities. Congenital anomalies of kidney and urinary tract are the commonest cause of chronic kidney disease in children. {ECO:0000269 PubMed:26235987}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for TBX18
No data available for Genatlas for TBX18 Gene
Publications for TBX18 Gene
- Identification, mapping and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19. (PMID: 9888994) Yi C.-H. … Brook J.D. (Genomics 1999) 2 3 4 67
- Direct conversion of quiescent cardiomyocytes to pacemaker cells by expression of Tbx18. (PMID: 23242162) Kapoor N. … Cho H.C. (Nat. Biotechnol. 2013) 2 3
- T-genes and limb bud development. (PMID: 16688725) King M. … Morrow B.E. (Am. J. Med. Genet. A 2006) 2 3
- Mutations in TBX18 cause dominant urinary tract malformations via transcriptional dysregulation of ureter development. (PMID: 26235987) Vivante A. … Hildebrandt F. (Am. J. Hum. Genet. 2015) 3
- A genome-wide association study for diabetic retinopathy in a Japanese population: potential association with a long intergenic non-coding RNA. (PMID: 25364816) Awata T. … Koike A. (PLoS ONE 2014) 3
Products for TBX18 Gene
- R&D Systems Antibodies for TBX18 (TBX18)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Browse Activity Assays
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- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for TBX18
- Search Origene for MassSpec and Protein Over-expression Lysates for TBX18
- Origene Custom Protein Services for TBX18
- Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for TBX18
- Browse OriGene Inhibitory RNA Products For TBX18
- OriGene qPCR primer pairs for TBX18
- OriGene CRISPR knockouts for TBX18
- OriGene clones in human for TBX18
- OriGene ORF clones in human,mouse,rat for TBX18
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for TBX18
- GenScript Custom Assay Services for TBX18
- GenScript Custom overexpressing Cell Line Services for TBX18
- GenScript: Design CRISPR guide RNA sequences for TBX18
- Design optimal peptide antigens
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- Gene Mutant Library, Variants up to 10^11
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- GenScript Custom Peptide Services for TBX18
- Novus Biologicals Antibodies for TBX18
- Novus Biologicals proteins and lysates for TBX18
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for TBX18: See all 50
- antibodies-online Kits for TBX18: See all 1
- antibodies-online Proteins for TBX18: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for TBX18
- Search GeneTex for Proteins for TBX18
- ViGene Biosciences adenoviral particle packaged cDNA for TBX18 gene
- ViGene Biosciences lentiviral particle packaged cDNA for TBX18 gene
- ViGene Biosciences lentiviral particle packaged cDNA for TBX18 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TBX18 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TBX18 gene
- ViGene Biosciences ready-to-package AAV shRNAs for TBX18 gene
- Search ViGene Biosciences for TBX18
- Search ViGene Biosciences for TBX18
- Santa Cruz Biotechnology (SCBT) Antibodies for TBX18
- Search Santa Cruz Biotechnology (SCBT) for TBX18 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for TBX18
Sources for TBX18 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
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