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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TBX18 Gene

protein-coding   GIFtS: 48
GCID: GC06M085444

T-box 18
 Explore 4 diseases affiliated with
TBX18 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TBX18    

Aliases
for TBX18 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
T-Box 181 2
T-Box Protein 182 3
T-Box Transcription Factor TBX182

External Ids:    HGNC: 115951   Entrez Gene: 90962   Ensembl: ENSG000001128377   OMIM: 6046135   UniProtKB: O959353   

Export aliases for TBX18 gene to outside databases

Previous GC identifers: GC06U990171 GC06M085413 GC06M085393 GC06M085453 GC06M085500 GC06M082667 GC06M085398


Summaries
for TBX18 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TBX18:
This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role
in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided
into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate
specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators
in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or
other transcription factors. (provided by RefSeq, Nov 2012)

UniProtKB/Swiss-Prot: TBX18_HUMAN, O95935
Function: Probable transcriptional regulator involved in developmental processes




Genomic Views
for TBX18 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007299.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TBX18 gene promoter:
         AREB6   MEF-2A   Ik-2   FOXO4   aMEF-2   Nkx2-5   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TBX18

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TBX18


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q14-q15   Ensembl cytogenetic band:  6q14.3   HGNC cytogenetic band: 6q14.1-q15

TBX18 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TBX18 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M085444:  view genomic region     (about GC identifiers)

Start:
 85,444,157 bp from pter      End:
 85,474,237 bp from pter
Size:
 30,081 bases      Orientation:
 minus strand

Proteins
for TBX18 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TBX18_HUMAN, O95935 (See protein sequence)
Recommended Name: T-box transcription factor TBX18  
Size: 607 amino acids; 64753 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: A2RU13 Q7Z6U4 Q9UJI6

Explore the universe of human proteins at neXtProt for TBX18: NX_O95935

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O95935

    • TBX18 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001073977.1  
    ENSEMBL proteins: 
     ENSP00000358677  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: TBX18
    OriGene Custom Protein Services for TBX18 
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    Novus Biologicals TBX18 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TBX18

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--


    TBX18 for ontologies           About GeneDecksing



    TBX18 Antibody Products: 
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    Assay Products for TBX18: 
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    Uscn ELISAs and CLIAs for TBX18

    Protein Domains /
    Families
    for TBX18 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TBX18 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001699 TF_T-box
     IPR008967 p53-like_TF_DNA-bd
     IPR018186 TF_T-box_CS

    Graphical View of Domain Structure for InterPro Entry O95935

    ProtoNet protein and cluster: O95935

    1 Blocks protein family: IPB001699 Transcription factor

    UniProtKB/Swiss-Prot: TBX18_HUMAN, O95935
    Similarity: Contains 1 T-box DNA-binding domain


    Function
    for TBX18 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TBX18_HUMAN, O95935
    Function: Probable transcriptional regulator involved in developmental processes

         Genatlas biochemistry entry for TBX18:
    murine T-box gene Tbx18 (T,brachyury) homolog

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TBX18
    8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate TBX18 (see all 16):
    hsa-miR-21* hsa-miR-3163 hsa-miR-205 hsa-miR-3614-3p hsa-miR-944 hsa-miR-410 hsa-miR-421 hsa-miR-33a*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TBX18 (see all 7)
    OriGene shRNA RFP: TBX18
    OriGene siRNA: TBX18
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TBX18

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TBX18

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TBX18 (see all 3)
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TBX18 (NM_001080508)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TBX18 

    Cell Line
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    Search LifeMap BioReagents cell lines for TBX18

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBX18

    Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000976transcription regulatory region sequence-specific DNA binding ISS--
    GO:0001106RNA polymerase II transcription corepressor activity ISS--
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--
    GO:0005515protein binding ----
    GO:0042803protein homodimerization activity ISS--


    TBX18 for ontologies           About GeneDecksing


    Animal Models:
         10 MGI mutant phenotypes (inferred from 8 alleles) (MGI details for Tbx18):
     cardiovascular system  craniofacial  embryogenesis  growth/size  integument 
     mortality/aging  nervous system  no phenotypic analysis  renal/urinary system  skeleton 

    TBX18 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for TBX18 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Selected targets of Oct-3/4
    		Selected targets of Oct-3/41.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for TBX18
        Selected targets of Oct-3/4




    TBX18 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TBX18

    Gene Ontology (GO): 5/15 biological process terms (GO ID links to tree view) (see all 15):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter ISS--
    GO:0001756somitogenesis IEA--
    GO:0002053positive regulation of mesenchymal cell proliferation ----
    GO:0003163sinoatrial node development IEA--
    GO:0007605sensory perception of sound IEA--


    TBX18 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TBX18 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TBX18
    Search CenterWatch for drugs/clinical trials and news about TBX18 

    Transcripts
    for TBX18 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TBX18 gene: 
    NM_001080508.2  

    Unigene Cluster for TBX18:

    T-box 18
    Hs.251830  [show with all ESTs]
    Unigene Representative Sequence: NM_001080508
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000369663(uc010kbq.2 uc003pkl.1)

    miRNA
    Products:             		 OriGene 3'-UTR Clone: TBX18
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TBX18
    8/16 QIAGEN miScript miRNA Assays for microRNAs that regulate TBX18 (see all 16):
    hsa-miR-21* hsa-miR-3163 hsa-miR-205 hsa-miR-3614-3p hsa-miR-944 hsa-miR-410 hsa-miR-421 hsa-miR-33a*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TBX18 (see all 7)
    OriGene shRNA RFP: TBX18
    OriGene siRNA: TBX18
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TBX18
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TBX18
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    GenScript: all cDNA clones in your preferred vector: TBX18 (NM_001080508)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TBX18
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TBX18 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TBX18
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TBX18
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TBX18

    Additional cDNA sequence: 

    AJ010278.1 AK310179.1 BC040697.2 BC132715.1 BC157841.1 

    8 DOTS entries:

    DT.40238800  DT.308320  DT.91850592  DT.100707679  DT.121344141  DT.75114827  DT.121381838  DT.92047601 

    11 AceView cDNA sequences:

    AL703333 H88260 BM453888 AI470177 BI492230 CB962166 AW023646 CB963170 
    H88049 AA331457 H89010 

    GeneLoc Exon Structure


    Expression
    for TBX18 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TBX18 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCAGAAAGAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TBX18 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    7 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    HeartEpicardiumEpicardial Progenitors CellsEpicardium
    Lateral Plate MesodermProepicardiumProepicardial Progenitor cellsEpicardium
    BrainBlood Brain BarrierPostnatal Endothelial CellsBlood Brain Barrier, Endothelium
    KidneyMetanephric MesenchymeMetanephric Mesenchyme CellsKidney
    LimbZeugopodMesenchymal Condensate CellsBone, Cartilage
    KidneyInterstitial StromaKidney
    LimbAutopodLimb
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TBX18 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TBX18

    SOURCE GeneReport for Unigene cluster: Hs.251830
        SABiosciences Custom PCR Arrays for TBX18
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBX18

    Orthologs
    for TBX18 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for TBX18 gene from 4/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TBX181 T-box 18 80.09(n)
    87.78(a)    		   395104  NM_204453.1  NP_989784.1 
    lizard
    (Anolis carolinensis)    		 Reptilia TBX186
    		 --
    		 82(a)
    		 1 ↔ 1
    		 1(196857733-196903413)
    zebrafish
    (Danio rerio)    		 Actinopterygii tbx182 T-box 18 73.67(n)   246223  AF448503.2 
    worm
    (Caenorhabditis elegans)    		 Secernentea mab-91 Protein MAB-9 51.63(n)
    50(a)    		   173441  NM_061349.5  NP_493750.1 


    ENSEMBL Gene Tree for TBX18 (if available)
    TreeFam Gene Tree for TBX18 (if available) 

    Paralogs
    for TBX18 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TBX18 gene
    TBX12  TBX222  TBX192  T2  EOMES2  TBX22  TBX62  TBX212  
    TBX32  TBX202  TBX52  TBX102  TBX42  TBR12  TBX152  
    15 SIMAP similar genes for TBX18 using alignment to 2 protein entries:     TBX18_HUMAN (see all proteins):
    TBX15    TBX22    TBX4    TBR1    TBX5    TBX2
    DKFZp762H2012    MGA    TBX20    TBX10    EOMES    T
    TBX6    TBX19    TBX1

    TBX18 for paralogs           About GeneDecksing



    Genomic Variants
    for TBX18 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/508 NCBI SNPs in TBX18 are shown (see all 508)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs796188991,2
    		C,other85457739(+) AAGATC/TGTCTC 2 N D mis11Minor allele frequency- T:0.01NA 180
    rs39205161,2
    		C,F,A,--85441903(+) AAAAAT/CGTTCT 1 -- ds50017Minor allele frequency- C:0.26NA WA EA 500
    rs787640251,2
    		F,--85441907(+) ATGTTC/TTAAAA 1 -- ds50011Minor allele frequency- T:0.12EA 120
    rs22069471,2
    		C,F,A,--85441982(+) AATAGA/GTGAAT 1 -- ds50013Minor allele frequency- G:0.13WA NA EA 358
    rs1481826581,2
    		--85442088(+) AAAATA/GTGGAT 1 -- ds50010--------
    rs16215301,2
    		C,F,H,--85442211(+) CACAAG/TTGTTT 1 -- ds500128Minor allele frequency- T:0.14NS EA NA WA CSA 2768
    rs1411518321,2
    		--85442523(+) TTTGTA/GAAGCC 1 -- ut310--------
    rs344315331,2
    		C,--85442539(+) TATAT-/TAATATA 1 -- ut310--------
    rs1508971941,2
    		--85442768(+) ATCCAC/TAGTCT 1 -- ut310--------
    rs1132601541,2
    		--85442891(+) ATATAT/ACTGTT 1 -- ut311Minor allele frequency- A:0.50CSA 2

    HapMap Linkage Disequilibrium report for TBX18 (85444157 - 85474237 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TBX18: --
    Human Gene Mutation Database (HGMD): TBX18

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TBX18
    DNA2.0 Custom Variant and Variant Library Synthesis for TBX18

    Disorders / Diseases
    for TBX18 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TBX18 for disorders           About GeneDecksing

    OMIM gene information: 604613    OMIM disorders: --

    4 diseases for TBX18:    About MalaCards
    campomelic dysplasia    renal agenesis    hydronephrosis    pharyngitis

    1 disease from the University of Copenhagen DISEASES database for TBX18:
    Hydronephrosis

    Export disorders for TBX18 gene to outside databases

    Publications
    for TBX18 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TBX18 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TBX18)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification, mapping and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19. (PubMed id 9888994)1, 2, 3 Yi C.-H.... Brook J.D. (1999)
    2. Direct conversion of quiescent cardiomyocytes to pacem aker cells by expression of Tbx18. (PubMed id 23242162)1, 3 Kapoor N....Cho H.C. (2013)
    3. T-genes and limb bud development. (PubMed id 16688725)1, 3 King M....Morrow B.E. (2006)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    5. Transcriptional suppression of connexin43 by TBX18 un dermines cell-cell electrical coupling in postnatal cardiomyocytes. (PubMed id 21205823)1 Kapoor N....Cho H.C. (2011)
    6. Setting the pace: Tbx3 and Tbx18 in cardiac conduction system development. (PubMed id 19213963)1 McNally E.M. and Svensson E.C. (2009)
    7. Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors. (PubMed id 17584735)1 Farin H.F....Kispert A. (2007)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for TBX18 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing TBX18 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9096 HGNC: 11595 AceView: TBX18.1 Ensembl:ENSG00000112837 euGenes: HUgn9096
    ECgene: TBX18 H-InvDB: TBX18

    Other Databases showing TBX18 gene

    (According to HUGE)
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    Specialized Databases showing TBX18 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TBX18 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    		Patent Information for TBX18 gene:
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