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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TBR1 Gene

protein-coding   GIFtS: 54
GCID: GC02P162272

T-box, brain, 1
 Explore 9 diseases affiliated with
TBR1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TBR1    

Aliases
for TBR1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
T-Box, Brain, 11 2
T-Brain-11
TBR-12 3
TES-562 3
T-Box Brain Protein 12

External Ids:    HGNC: 115901   Entrez Gene: 107162   Ensembl: ENSG000001365357   OMIM: 6046165   UniProtKB: Q166503   

Export aliases for TBR1 gene to outside databases

Previous GC identifers: GC02P160326 GC02P160800 GC02P162236 GC02P162475 GC02P162098 GC02P161980 GC02P154157


Summaries
for TBR1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TBR1:
This gene is a member of a conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes
encode transcription factors involved in the regulation of developmental processes. A similar protein has been
disrupted in mice and shown to be critical for early cortical development, and causes loss of projection neurons in
the olfactory bulbs and olfactory cortex. The C-terminal region this similar protein was found to be necessary and
sufficient for association with the guanylate kinase domain of calcium/calmodulin-dependent serine protein kinase.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: TBR1_HUMAN, Q16650
Function: Probable transcriptional regulator involved in developmental processes. TBR1 is required for normal brain
development

Gene Wiki entry for TBR1


Genomic Views
for TBR1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TBR1 gene promoter:
         HOXA9B   HOXA9   RelA   NF-kappaB   Tal-1beta   Meis-1b   E47   FAC1   NF-kappaB1   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TBR1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TBR1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TBR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q24   Ensembl cytogenetic band:  2q24.2   HGNC cytogenetic band: 2q24.2

TBR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TBR1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P162272:  view genomic region     (about GC identifiers)

Start:
 162,272,605 bp from pter      End:
 162,282,381 bp from pter
Size:
 9,777 bases      Orientation:
 plus strand

Proteins
for TBR1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TBR1_HUMAN, Q16650 (See protein sequence)
Recommended Name: T-box brain protein 1  
Size: 682 amino acids; 74053 Da
Subcellular location: Nucleus (Potential)
Secondary accessions: Q14DC5 Q53TH0

Explore the universe of human proteins at neXtProt for TBR1: NX_Q16650

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q16650

    • TBR1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_006584.1  
    ENSEMBL proteins: 
     ENSP00000374205   ENSP00000393934   ENSP00000387023  

    Human Recombinant Protein Products: 
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    Novus Biologicals TBR1 Protein
    Novus Biologicals TBR1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TBR1

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IEA--


    TBR1 for ontologies           About GeneDecksing



    TBR1 Antibody Products: 
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    Uscn ELISAs and CLIAs for TBR1

    Protein Domains /
    Families
    for TBR1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TBR1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001699 TF_T-box
     IPR008967 p53-like_TF_DNA-bd
     IPR018186 TF_T-box_CS

    Graphical View of Domain Structure for InterPro Entry Q16650

    ProtoNet protein and cluster: Q16650

    1 Blocks protein family: IPB001699 Transcription factor

    UniProtKB/Swiss-Prot: TBR1_HUMAN, Q16650
    Similarity: Contains 1 T-box DNA-binding domain


    Function
    for TBR1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TBR1_HUMAN, Q16650
    Function: Probable transcriptional regulator involved in developmental processes. TBR1 is required for normal brain
    development

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TBR1
    8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate TBR1 (see all 29):
    hsa-miR-582-3p hsa-miR-513a-5p hsa-miR-200a hsa-miR-181c* hsa-miR-944 hsa-miR-639 hsa-miR-29b-1* hsa-miR-1273d
    SwitchGear 3'UTR luciferase reporter plasmid: TBR1 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TBR1 (see all 4)
    OriGene shRNA RFP: TBR1
    OriGene siRNA: TBR1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TBR1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TBR1

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TBR1 (see all 2)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TBR1 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for TBR1
    Search LifeMap BioReagents cell lines for TBR1

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBR1

    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000979RNA polymerase II core promoter sequence-specific DNA binding IEA--
    GO:0003677DNA binding ----
    GO:0003700sequence-specific DNA binding transcription factor activity IEA--


    TBR1 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Tbr1tm1Jlr for TBR1
         3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Tbr1):
     behavior/neurological  mortality/aging  nervous system 

    TBR1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for TBR1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TBR1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/6 Interacting proteins for TBR1 (Q166503 ENSP000003742054) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CASKO149363, ENSP000003674084I2D: score=3 STRING: ENSP00000367408
    RFXANKO145933, ENSP000003050714I2D: score=1 STRING: ENSP00000305071
    TSPYL2Q9H2G43, ENSP000003645914I2D: score=1 STRING: ENSP00000364591
    IKBKEQ141643I2D: score=1 
    KNCNENSP000003796074STRING: ENSP00000379607
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0007411axon guidance IEA--
    GO:0007420brain development TAS7619531
    GO:0010092specification of organ identity IEA--


    TBR1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TBR1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TBR1
    Search CenterWatch for drugs/clinical trials and news about TBR1 

    Transcripts
    for TBR1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TBR1 gene: 
    NM_006593.2  

    Unigene Cluster for TBR1:

    T-box, brain, 1
    Hs.210862  [show with all ESTs]
    Unigene Representative Sequence: NM_006593
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000389554(uc002ubw.1 uc010foy.2) ENST00000463544 ENST00000411412
    ENST00000410035 ENST00000477804 ENST00000489530

    miRNA
    Products:             		 OriGene 3'-UTR Clone: TBR1
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TBR1
    8/29 QIAGEN miScript miRNA Assays for microRNAs that regulate TBR1 (see all 29):
    hsa-miR-582-3p hsa-miR-513a-5p hsa-miR-200a hsa-miR-181c* hsa-miR-944 hsa-miR-639 hsa-miR-29b-1* hsa-miR-1273d
    SwitchGear 3'UTR luciferase reporter plasmid: TBR1 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TBR1 (see all 4)
    OriGene shRNA RFP: TBR1
    OriGene siRNA: TBR1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TBR1
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TBR1 (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TBR1
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    GenScript: all cDNA clones in your preferred vector: TBR1 (NM_006593)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TBR1
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    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TBR1
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TBR1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TBR1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TBR1

    Additional cDNA sequence: 

    AK297168.1 AK297438.1 AK299533.1 AK312567.1 AK315865.1 AK316161.1 BC029289.1 BC104844.1 
    BC113418.1 U49250.1 

    4 DOTS entries:

    DT.411994  DT.97768769  DT.92415690  DT.121003291 

    24/50 AceView cDNA sequences (see all 50):

    NM_006593 BC029289 D56477 BI912693 BM548197 BX420367 BM922065 AI815469 
    BI757271 U49250 AI869758 BI918360 BI914330 AI201654 BX418656 BI917781 
    BM807553 BI820633 AW163382 AW160871 AW003023 BQ067178 BX418703 BI823704 

    GeneLoc Exon Structure


    Expression
    for TBR1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TBR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAATAATTAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TBR1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainBlood Brain BarrierEndothelial CellsBlood Brain Barrier, Endothelium
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TBR1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TBR1

    SOURCE GeneReport for Unigene cluster: Hs.210862

    UniProtKB/Swiss-Prot: TBR1_HUMAN, Q16650
    Tissue specificity: Brain

        SABiosciences Custom PCR Arrays for TBR1
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBR1

    Orthologs
    for TBR1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for TBR1 gene from 3/14 species (see all 14)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves LOC4290291 T-box brain protein 1-like 89.59(n)
    94.89(a)    		   429029  XM_003641638.1  XP_003641686.1 
    lizard
    (Anolis carolinensis)    		 Reptilia TBR16
    		 --
    		 81(a)
    		 1 ↔ 1
    		 GL343359.1(1062410-1078505)
    zebrafish
    (Danio rerio)    		 Actinopterygii tbr12 T-box 1, brain 76.05(n)   58042  AF287006.1 


    ENSEMBL Gene Tree for TBR1 (if available)
    TreeFam Gene Tree for TBR1 (if available) 

    Paralogs
    for TBR1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TBR1 gene
    TBX12  TBX222  TBX192  T2  EOMES2  TBX22  TBX62  TBX212  
    TBX32  TBX202  TBX52  TBX102  TBX42  TBX152  TBX182  
    9 SIMAP similar genes for TBR1 using alignment to 4 protein entries:     TBR1_HUMAN (see all proteins):
    MGA    TBX18    EOMES    TBX5    TBX19    TBX21
    TBX10    TBX6    T

    TBR1 for paralogs           About GeneDecksing



    Genomic Variants
    for TBR1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/145 NCBI SNPs in TBR1 are shown (see all 145)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs2017686801,2
    		--162270651(+) CTCAT-/GAGGGCAA
    ATGGCAGTAG    GAGGG     		1 -- us2k10--------
    rs1179824421,2
    		F,--162270652(+) CTCATG/AAGGGC 1 -- us2k11Minor allele frequency- A:0.03EA 120
    rs1871671251,2
    		--162270654(+) CATGAA/GGGCAA 1 -- us2k10--------
    rs15596291,2
    		C,F,O,H,--162270728(+) CGCACC/TCCAAC 1 -- us2k1 tfbs312Minor allele frequency- T:0.12MN NS EA NA 1614
    rs58358681,2
    		C--162270821(+) CTCTC-/TTTTTAT 1 -- us2k1 trp31Minor allele frequency- TT:0.00NA 2
    rs1509849351,2
    		C,--162270821(+) CTCTC-/TTTTTAT 1 -- us2k10--------
    rs1113672431,2
    		C--162270822(+) TCTCTC/TTTTAT 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs748242501,2
    		C--162270824(+) TCTTTA/TTATCC 1 -- us2k10--------
    rs1157502461,2
    		F,--162271136(+) CCCGGC/ACCGGG 1 -- us2k11Minor allele frequency- A:0.18WA 118
    rs785551271,2
    		F,--162271260(+) CCCTTG/TCTCCT 1 -- us2k12Minor allele frequency- T:0.12NA EA 240

    HapMap Linkage Disequilibrium report for TBR1 (162272605 - 162282381 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TBR1: --
    Human Gene Mutation Database (HGMD): TBR1

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TBR1
    DNA2.0 Custom Variant and Variant Library Synthesis for TBR1

    Disorders / Diseases
    for TBR1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TBR1 for disorders           About GeneDecksing

    OMIM gene information: 604616    OMIM disorders: --

    9 diseases for TBR1:    About MalaCards
    ellis-van creveld syndrome    sleeping sickness    intellectual disability    neuronitis
    microcephaly    pharyngitis    colorectal cancer    cerebritis
    schizophrenia

    2 diseases from the University of Copenhagen DISEASES database for TBR1:
    Sleeping sickness     Microcephaly
    Genetic Association Database (GAD): TBR1
    Human Genome Epidemiology (HuGE) Navigator: TBR1 (1 document)

    Export disorders for TBR1 gene to outside databases

    Publications
    for TBR1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TBR1 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with TBR1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. T-brain-1: a homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex. (PubMed id 7619531)1, 2, 3 Bulfone A....Rubenstein J.L.R. (1995)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. TbetaR-I(6A) polymorphism is not a tumor susceptibility allele in Macedonian colorectal cancer patients. Correspondence re: B. Pasche et al. Type I TbetaR-I(6A) Is a Candidate Tumor Susceptibility Allele. Cancer Res., 58: 2727-2732, 1998. (PubMed id 11719470)1, 4 Stefanovska A.M....Spiroski M. (2001)
    5. Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
    6. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    7. Transcriptional modification by a CASK-interacting nucleosome assembly protein. (PubMed id 15066269)1 Wang G.S....Hsueh Y.P. (2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    9. Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2. (PubMed id 10749215)1 Hsueh Y.P....Sheng M. (2000)
    10. MRNA expression patterns and distribution of white matter neurons in dorsolateral prefrontal cortex of depressed patients differ from those in schizophrenia patients. (PubMed id 12513943)9 Molnar M....Jones E.G. (2003)

    External Searches for TBR1 gene

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    Genome Databases showing TBR1 gene

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    Entrez Gene: 10716 HGNC: 11590 AceView: TBR1 Ensembl:ENSG00000136535 euGenes: HUgn10716
    ECgene: TBR1 H-InvDB: TBR1

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    Specialized Databases showing TBR1 gene

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