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TBCEL Gene

protein-coding   GIFtS: 50
GCID: GC11P120894

Tubulin Folding Cofactor E-Like

(Previous names: leucine rich repeat containing 35, tubulin-specific chaperone...)
(Previous symbol: LRRC35)
  Search for TBCEL
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tubulin Folding Cofactor E-Like1 2     EL3 5
LRRC351 2 3 5     E-like2
Leucine Rich Repeat Containing 351 2     El2
Tubulin-Specific Chaperone E-Like1 2     catastrophin2
Leucine-Rich Repeat-Containing Protein 352 3     Tubulin-Specific Chaperone Cofactor E-Like Protein2

External Ids:    HGNC: 281151   Entrez Gene: 2198992   Ensembl: ENSG000001541147   OMIM: 6104515   UniProtKB: Q5QJ743   

Export aliases for TBCEL gene to outside databases

Previous GC identifers: GC11P120403 GC11P116834


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TBCEL Gene:
TBCEL (tubulin folding cofactor E-like) is a protein-coding gene. An important paralog of this gene is TBCE.

UniProtKB/Swiss-Prot: TBCEL_HUMAN, Q5QJ74
Function: Acts as a regulator of tubulin stability




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000011.10  NT_033899.9  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TBCEL gene promoter:
         p53   NRSF form 1   NF-kappaB1   NF-kappaB   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTBCEL promoter sequence
   Search Chromatin IP Primers for TBCEL

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TBCEL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.3   Ensembl cytogenetic band:  11q23.3   HGNC cytogenetic band: 11q23.3

TBCEL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TBCEL gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P120894:  view genomic region     (about GC identifiers)

Start:
120,894,781 bp from pter      End:
120,961,484 bp from pter
Size:
66,704 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TBCEL_HUMAN, Q5QJ74 (See protein sequence)
Recommended Name: Tubulin-specific chaperone cofactor E-like protein  
Size: 424 amino acids; 48195 Da
Secondary accessions: Q0VAN6

Explore the universe of human proteins at neXtProt for TBCEL: NX_Q5QJ74

Explore proteomics data for TBCEL at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys236
  • Modification sites at PhosphoSitePlus

  • See TBCEL Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001123519.1  NP_689928.3  

    ENSEMBL proteins: 
     ENSP00000437184   ENSP00000284259   ENSP00000431803   ENSP00000433365   ENSP00000403925  
     ENSP00000431156   ENSP00000432783   ENSP00000436419  

    TBCEL Human Recombinant Protein Products:

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    Novus Biologicals TBCEL Protein
    Novus Biologicals TBCEL Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for TBCEL
    Cloud-Clone Corp. Proteins for TBCEL

     
    Search eBioscience for Proteins for TBCEL 

    TBCEL Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals TBCEL Antibodies
    Abcam antibodies for TBCEL
    Cloud-Clone Corp. Antibodies for TBCEL
    Search ThermoFisher Antibodies for TBCEL
    LSBio Antibodies in human, mouse, rat for TBCEL

    TBCEL Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TBCEL
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TBCEL
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TBCEL
    Cloud-Clone Corp. CLIAs for TBCEL
    Search eBioscience for ELISAs for TBCEL 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR027933 Ubiquitin-like_dom
     IPR000626 Ubiquitin_dom

    Graphical View of Domain Structure for InterPro Entry Q5QJ74

    ProtoNet protein and cluster: Q5QJ74

    2 Blocks protein domains:
    IPB000626 Ubiquitin domain
    IPB001611 Leucine-rich repeat signature


    UniProtKB/Swiss-Prot: TBCEL_HUMAN, Q5QJ74
    Similarity: Contains 7 LRR (leucine-rich) repeats
    Similarity: Contains 1 LRRCT domain
    Similarity: Contains 1 ubiquitin-like domain


    Find genes that share domains with TBCEL           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TBCEL_HUMAN, Q5QJ74
    Function: Acts as a regulator of tubulin stability

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with TBCEL           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TBCEL
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TBCEL

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TBCEL
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TBCEL

    miRNA
    Products:
        
    miRTarBase miRNAs that target TBCEL:
    hsa-mir-92a-3p (MIRT049522)

    Block miRNA regulation of human, mouse, rat TBCEL using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TBCEL (see all 40):
    hsa-miR-136 hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-3616-5p hsa-miR-519a hsa-miR-4275 hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidTBCEL 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TBCEL
    Predesigned siRNA for gene silencing in human, mouse, rat TBCEL

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TBCEL

    Clone
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    OriGene clones in human, mouse for TBCEL (see all 12)
    OriGene ORF clones in mouse, rat for TBCEL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TBCEL (NM_152715)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TBCEL
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TBCEL

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TBCEL
    Browse ESI BIO Cell Lines and PureStem Progenitors for TBCEL 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBCEL


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TBCEL_HUMAN, Q5QJ74: Cytoplasm, cytoskeleton (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton4
    cytosol3
    nucleus2
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--

    Find genes that share ontologies with TBCEL           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TBCEL
    Interactions:

        Search GeneGlobe Interaction Network for TBCEL

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for TBCEL (ENSP000002842594) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAD1L1ENSP000003825624STRING: ENSP00000382562
    PSMD12ENSP000003484424STRING: ENSP00000348442
    MAD2L1ENSP000002965094STRING: ENSP00000296509
    PSMD2ENSP000003101294STRING: ENSP00000310129
    PSMD4ENSP000003578794STRING: ENSP00000357879
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TBCEL



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TBCEL gene (2 alternative transcripts): 
    NM_001130047.1  NM_152715.3  

    Unigene Cluster for TBCEL:

    Tubulin folding cofactor E-like
    Hs.504136  [show with all ESTs]
    Unigene Representative Sequence: NM_152715
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000529397 ENST00000284259 ENST00000528512 ENST00000531148 ENST00000422003(uc009zay.3 uc001pxo.3 uc001pxp.3 uc001pxq.3)
    ENST00000533712 ENST00000524726 ENST00000530362 ENST00000533134 ENST00000533169

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TBCEL using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TBCEL (see all 40):
    hsa-miR-136 hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-3616-5p hsa-miR-519a hsa-miR-4275 hsa-miR-105
    SwitchGear 3'UTR luciferase reporter plasmidTBCEL 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TBCEL
    Predesigned siRNA for gene silencing in human, mouse, rat TBCEL
    Clone
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    OriGene clones in human, mouse for TBCEL (see all 12)
    OriGene ORF clones in mouse, rat for TBCEL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TBCEL (NM_152715)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TBCEL
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TBCEL
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TBCEL
    OriGene qSTAR qPCR primer pairs in human, mouse for TBCEL
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TBCEL
      QuantiTect SYBR Green Assays in human, mouse, rat TBCEL
      QuantiFast Probe-based Assays in human, mouse, rat TBCEL

    Additional mRNA sequence: 

    AK024239.1 AK295673.1 AK313324.1 AY398644.1 BC020501.1 BC120988.1 BC120989.1 

    6 DOTS entries:

    DT.446404  DT.412432  DT.95367827  DT.92038208  DT.97813987  DT.99965230 

    Selected AceView cDNA sequences (see all 109):

    AI754986 CA389856 AA809962 CA314589 BE672045 AW594223 AI269747 AI801110 
    CR616944 AA041197 AI570238 AI569190 AL041380 NM_152715 BQ890649 AW117238 
    AA860582 AI359838 AI655722 W69990 AI884394 BI833150 AI200940 BX281438 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TBCEL (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b
    SP1:              -     -                       -                       -                           
    SP2:                                            -     -     -     -     -                           
    SP3:              -     -                                               -                           
    SP4:                                            -                                                   
    SP5:              -                                                                                 


    ECgene alternative splicing isoforms for TBCEL

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TBCEL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGTACTTATA
    TBCEL Expression
    About this image

    TBCEL Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TBCEL Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.504136

    UniProtKB/Swiss-Prot: TBCEL_HUMAN, Q5QJ74
    Tissue specificity: Abundantly expressed in testis, but is also present in several tissues at a much lower level

        Custom PCR Arrays for TBCEL
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    QuantiFast Probe-based Assays in human, mouse, rat TBCEL
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBCEL

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TBCEL gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tbcel1 , 5 tubulin folding cofactor E-like1, 5 88.92(n)1
    97.41(a)1
      9 (23.71 cM)5
    2725891  NM_173038.31  NP_766626.11 
     424123165 
    chicken
    (Gallus gallus)
    Aves TBCEL1 tubulin folding cofactor E-like 80.42(n)
    89.39(a)
      429536  XM_427094.3  XP_427094.2 
    lizard
    (Anolis carolinensis)
    Reptilia TBCEL6
    tubulin folding cofactor E-like
    89(a)
    1 ↔ 1
    LGa(2114522-2139103)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tbcel1 tubulin folding cofactor E-like 73.9(n)
    79.25(a)
      100125781  NM_001105283.1  NP_001098753.1 
    zebrafish
    (Danio rerio)
    Actinopterygii BM342099.12   -- 73.99(n)    BM342099.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG122141 CG12214 48.33(n)
    42(a)
      36072  NM_001273924.1  NP_001260853.1 
    worm
    (Caenorhabditis elegans)
    Secernentea coel-11 coel-1 44.23(n)
    31.87(a)
      180700  NM_171665.3  NP_741764.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes PAC26
    Microtubule effector required for tubulin heterodi...
    17(a)
    1 → many
    V(164527-166083) YER007W


    ENSEMBL Gene Tree for TBCEL (if available)
    TreeFam Gene Tree for TBCEL (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TBCEL gene
    TBCE2  

    Find genes that share paralogs with TBCEL           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TBCEL (see all 1253)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1122253611,2
    C,F--120892842(+) CTGGTG/AGGGAC 2 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs801636931,2
    F--120892933(+) GCCAAC/TCAGCA 2 -- us2k12Minor allele frequency- T:0.50NA 4
    rs1897463791,2
    --120892958(+) CAGGAG/TTTGTG 2 -- us2k10--------
    rs1821698891,2
    --120893035(+) CTCTGG/TATCTA 2 -- us2k10--------
    rs112181141,2
    C,F--120893054(+) GGTGGG/AGAGGT 2 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1864832931,2
    --120893150(+) GGATGC/TGGGTG 2 -- us2k10--------
    rs112181151,2
    C--120893187(+) CTGCCC/AGAGCC 2 -- us2k1 tfbs31Minor allele frequency- A:0.00NA 2
    rs1913644971,2
    --120893217(+) GGTCCC/TTTTCC 2 -- us2k10--------
    rs1828321931,2
    --120893279(+) TCACTC/TTTTGG 2 -- us2k10--------
    rs1887463901,2
    --120893338(+) CTTCAC/GTCCGG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for TBCEL (120894781 - 120961484 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TBCEL:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv524651CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TBCEL
    DNA2.0 Custom Variant and Variant Library Synthesis for TBCEL

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610451    OMIM disorders: --


    Find genes that share disorders with TBCEL           About GenesLikeMe

    Genetic Association Database (GAD): TBCEL
    Human Genome Epidemiology (HuGE) Navigator: TBCEL (1 document)

    Export disorders for TBCEL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TBCEL gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TBCEL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a novel tubulin-destabilizing protein related to the chaperone cofactor E. (PubMed id 15728251)1, 2, 3 Bartolini F....Cowan N.J. (J. Cell Sci. 2005)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    5. Op18/Stathmin counteracts the activity of overexpressed tubulin-disrupting proteins in a human leukemia cell line. (PubMed id 18262179)1 Sellin M.E....Gullberg M. (Exp. Cell Res. 2008)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. Possible regulation of microtubules through destabilization of tubulin. (PubMed id 16202601)9 Keller C.E. and Lauring B.P. (Trends Cell Biol. 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 219899 HGNC: 28115 AceView: MGC10233 Ensembl:ENSG00000154114 euGenes: HUgn219899
    ECgene: TBCEL H-InvDB: TBCEL

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TBCEL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TBCEL gene:
    Search GeneIP for patents involving TBCEL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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