TBCE Gene
protein-coding GIFtS: 57
GCID: GC01P235530
|
|
tubulin folding cofactor E(Previous names: tubulin-specific chaperone e, Kenny-Caffey syndrome )
(Previous symbol: KCS)
| |
Aliases
for TBCE gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Tubulin Folding Cofactor E1 2 | | Kenny-Caffey Syndrome1 2 | | HRD1 2 5 | | Pac21 | | KCS1 2 5 | | Tubulin-Specific Chaperone E1 2 | | KCS11 2 5 | | Tubulin-Folding Cofactor E2 3 |
Export aliases for TBCE gene to outside databasesPrevious GC identifers: GC01P233663 GC01P230984 GC01P231827 GC01P232571 GC01P231856 GC01P205979 |
Summaries
for TBCE gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TBCE:
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly foldedbeta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizingbeta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex;interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the nativestate. Two transcript variants encoding the same protein have been found for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: TBCE_HUMAN, Q15813Function: Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicatedin the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation
Gene Wiki entry for TBCE
|
Genomic Views
for TBCE gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167186.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TBCE gene promoter:
USF1 SREBP-1c USF2 USF-1:USF-2 SREBP-1b N-Myc SREBP-1a USF-1 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for TBCE
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TBCE |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q42.3 Ensembl cytogenetic band: 1q42.3 HGNC cytogenetic band: 1q42.3TBCE Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P235530: view genomic region
(about GC identifiers)
Start:
|
235,530,675 bp from pter |
End:
|
235,612,283 bp from pter |
Size:
|
81,609 bases |
Orientation:
|
plus strand |
|
Proteins
for TBCE gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TBCE_HUMAN, Q15813 (See
protein sequence)Recommended Name: Tubulin-specific chaperone E Size: 527 amino acids; 59346 Da
Subunit: Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in aquasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causesthe release of tubulin polypeptides that are committed to the native state. Cofactors B and E can form a heterodimerwhich binds to alpha-tubulin and enhances their ability to dissociate tubulin heterodimers
Subcellular location: Cytoplasm (By similarity). Cytoplasm, cytoskeleton (By similarity)Explore the universe of human proteins at neXtProt for TBCE: NX_Q15813
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q15813
TBCE Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001072983.1 NP_003184.1
ENSEMBL proteins: ENSP00000355560 ENSP00000384571 ENSP00000439170 Reactome Protein details: Q15813
Human Recombinant Protein Products for TBCE:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
TBCE for ontologies About GeneDecksing
TBCE Antibody Products:
Assay Products for TBCE: |
Protein
Domains /
Families
for TBCE gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TBCE for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q15813ProtoNet protein and cluster: Q15813 1 Blocks protein family: IPB000938 CAP-Gly domain
UniProtKB/Swiss-Prot: TBCE_HUMAN, Q15813Similarity: Belongs to the TBCE familySimilarity: Contains 1 CAP-Gly domainSimilarity: Contains 7 LRR (leucine-rich) repeatsSimilarity: Contains 1 LRRCT domain |
Function
for TBCE gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: TBCE_HUMAN, Q15813Function: Tubulin-folding protein; involved in the second step of the tubulin folding pathway. Seems to be implicatedin the maintenance of the neuronal microtubule network. Involved in regulation of tubulin heterodimer dissociation Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
TBCE for ontologies About GeneDecksing
Phenotypes:
5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Tbce):
TBCE for phenotypes About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TBCE (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TBCE (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TBCE (NM_003193) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TBCE | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TBCE |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBCE |
|
Pathways & Interactions
for TBCE gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Chaperonin-mediated protein folding | | | 2 | Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane | | | 3 | Asparagine N-linked glycosylation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for TBCE
TBCE for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TBCE
STRING Interaction
Network Preview (showing 5 interactants - click image to see 12)
5/33 Interacting proteins for TBCE (Q158133 ENSP000003555604) via UniProtKB, MINT, STRING, and/or I2D (see all 33)About this table
Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12): About this table
TBCE for ontologies About GeneDecksing
|
Drugs & Compounds
for TBCE gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TBCE
Search CenterWatch for drugs/clinical trials and news about TBCE
|
Transcripts
for TBCE gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TBCE gene (2 alternative transcripts): NM_001079515.1 NM_003193.3 Unigene Cluster for TBCE: Tubulin folding cofactor E Hs.498143 [show with all ESTs]Unigene Representative Sequence: AK2961857 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000366601(uc001hwz.1) ENST00000482230 ENST00000472011(uc001hxb.1)
ENST00000461651 ENST00000465463 ENST00000406207(uc001hxa.1) ENST00000543662(uc010pxq.1 uc010pxr.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TBCE (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TBCE (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): TBCE (NM_003193) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TBCE | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TBCE |
Additional cDNA sequence: AK093397.1 AK292287.1 AK296185.1 AK298050.1 BC008654.1 BT007086.1 U61232.1 18 DOTS entries: DT.100789308 DT.97844301 DT.452426 DT.121438774 DT.86853790 DT.100789309 DT.100789304 DT.121438919 DT.121438674 DT.100789307 DT.121438739 DT.121438842 DT.40132122 DT.40210627 DT.97779234 DT.40110379 DT.40119049 DT.95124398 24/149 AceView cDNA sequences (see all 149): BI760545 AA766244 BU192730 AL533627 CA432027 BE783109 BE891661 CR612606 CR599260 BM463617 BC008654 BX452392 CB123405 BE930422 AU132583 CF527732 AA349080 AU151375 BM701222 BM788830 CB851293 AA504618 BQ681955 CA487710
GeneLoc Exon Structure
|
Expression
for TBCE gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TBCE expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACAATTCAAA
About this image
See TBCE Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TBCE
SOURCE GeneReport for Unigene cluster: Hs.498143
SABiosciences Custom PCR Arrays for TBCE
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TBCE
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TBCE | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TBCE | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TBCE | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBCE |
Orthologs
for TBCE gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TBCE gene from 9/26 species (see all 26) About this table
ENSEMBL Gene Tree for TBCE (if available)
TreeFam Gene Tree for TBCE (if available) |
Paralogs
for TBCE gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TBCE gene
- TBCEL2
1 SIMAP similar gene for TBCE using alignment to 2 protein entries: TBCE_HUMAN (see all proteins):RPS21
TBCE for paralogs About GeneDecksing
|
Genomic Variants
for TBCE gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TBCE (235530675 - 235612283 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for TBCE
3 CNVs: 48278 97677 34781
Human Gene Mutation Database (HGMD): TBCE
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TBCE |
|
Disorders
/ Diseases
for TBCE gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TBCE for disorders About GeneDecksing
OMIM gene information: 604934
OMIM disorders: 244460 241410
UniProtKB/Swiss-Prot: TBCE_HUMAN, Q15813
Defects in TBCE are a cause of hypoparathyroidism-retardation-dysmorphism syndrome (HRD) [MIM:241410]; alsoknown as hypoparathyroidism with short stature, mental retardation, and seizures or Sanjad-Sakati syndrome. HRD is anautosomal recessive disorder reported almost exclusively in Middle Eastern populations Defects in TBCE are the cause of Kenny-Caffey syndrome type 1 (KCS1) [MIM:244460]. KCS1 is similar to HRD withthe additional features of osteosclerosis and recurrent bacterial infections
20/22  diseases for TBCE (see all 22): About MalaCardskenny-caffey syndrome kenny-caffey syndrome type 1 hypoparathyroidism-retardation-dysmorphism syndrome hypoparathyroidism short stature mental retardation
sakati syndrome retinitis pigmentosa-2 hypoparathyroidism short stature
seborrheic keratosis motor neuronopathy hypodermyiasis pituitary hormone deficiency
corpus callosum retinitis pigmentosa osteosclerosis keratosis
retinitis dermatitis psoriasis thyroiditis
5 diseases from the University of Copenhagen DISEASES database for TBCE:Caffey disease Hypoparathyroidism Psoriasis Dermatitis
Hypodermyiasis 2 Novoseek disease relationships for TBCE gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| sanjad-sakati syndrome |
98.8 |
4 |
17184771 (1), 19491227 (1), 16624573 (1), 16470743 (1) |
| hypoparathyroidism |
80.2 |
1 |
17664687 (1) |
Human Genome Epidemiology (HuGE) Navigator: TBCE (2 documents)
Export disorders for TBCE gene to outside databases
|
Publications
for TBCE gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TBCE gene, integrated from 9 sources (see all 40):
(articles sorted by number of sources associating them with TBCE) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mutation of TBCE causes hypoparathyroidism-retardation-dysmorphism and autosomal recessive Kenny-Caffey syndrome. (PubMed id 12389028)1, 2, 3, 9 Parvari R.... Gelb B.D. (2002)
- Pathway leading to correctly folded beta-tubulin. (PubMed id 8706133)1, 2, 3 Tian G....Cowan N.J. (1996)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C. (PubMed id 11847227)1, 2 Bartolini F....Cowan N.J. (2002)
- The autosomal recessive Kenny-Caffey syndrome locus maps to chromosome 1q42-q43. (PubMed id 9806825)1, 3 Diaz G.A....Gelb B.D. (1998)
- Role of cofactors B (TBCB) and E (TBCE) in tubulin heterodimer dissociation. (PubMed id 17184771)1, 9 Kortazar D....Zabala J.C. (2007)
- Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease. (PubMed id 12446740)1, 9 Bommel H....Sendtner M. (2002)
- Mutation in the TBCE gene is associated with hypopara thyroidism-retardation-dysmorphism syndrome featuring pituitary hormone deficie ncies and hypoplasia of the anterior pituitary and the corpus callosum. (PubMed id 19491227)1, 9 Padidela R....Dattani M.T. (2009)
- A missense mutation in Tbce causes progressive motor neuronopathy in mice. (PubMed id 12389029)1, 9 Martin N....Guenet J.L. (2002)
|
External Searches for TBCE gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TBCE gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TBCE gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TBCE gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TBCE | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TBCE gene:
Search GeneIP for patents involving TBCE
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TBCE gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TBCE | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TBCE | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TBCE | | | OriGene Protein Over-expression Lysate for TBCE | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TBCE | | OriGene 3'-UTR Clone for TBCE | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TBCE | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TBCE | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TBCE | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TBCE | | OriGene Custom Protein Services for TBCE | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TBCE | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TBCE | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TBCE | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TBCE | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TBCE | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TBCE |
| |
 |  |  |  | |
| | | | Search Tocris compounds for TBCE |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | TBCE Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBCE |
|  |  |  |  | | | | ThermoFisher Antibodies for TBCE |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TBCE |
| |  | |
|
|
|
