Aliases for TBCC Gene
External Ids for TBCC Gene
Previous GeneCards Identifiers for TBCC Gene
Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008]
GeneCards Summary for TBCC Gene
TBCC (Tubulin Folding Cofactor C) is a Protein Coding gene. Diseases associated with TBCC include retinitis pigmentosa 2 and retinitis pigmentosa. Among its related pathways are Transport to the Golgi and subsequent modification and Protein folding. GO annotations related to this gene include GTPase activity and chaperone binding. An important paralog of this gene is RP2.
UniProtKB/Swiss-Prot for TBCC Gene
Tubulin-folding protein; involved in the final step of the tubulin folding pathway.