Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TBC1D9B Gene

protein-coding   GIFtS: 48
GCID: GC05M179289

TBC1 Domain Family, Member 9B (With GRAM Domain)

  Search for TBC1D9B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
TBC1 Domain Family, Member 9B (With GRAM Domain)1 2
TBC1 Domain Family Member 9B2
KIAA06763

External Ids:    HGNC: 290971   Entrez Gene: 230612   Ensembl: ENSG000001972267   UniProtKB: Q66K143   

Export aliases for TBC1D9B gene to outside databases

Previous GC identifers: GC05M179222 GC05M179223 GC05M174013


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TBC1D9B Gene:
TBC1D9B (TBC1 domain family, member 9B (with GRAM domain)) is a protein-coding gene. GO annotations related to this gene include Rab GTPase activator activity and calcium ion binding. An important paralog of this gene is TBC1D2.

UniProtKB/Swiss-Prot: TBC9B_HUMAN, Q66K14
Function: May act as a GTPase-activating protein for Rab family protein(s)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000005.9  NC_018916.2  NT_023133.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the TBC1D9B gene promoter:
         NRSF form 1   SEF-1 (1)   Pax-2   Pax-2a   NRSF form 2   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTBC1D9B promoter sequence
   Search Chromatin IP Primers for TBC1D9B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TBC1D9B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.3   Ensembl cytogenetic band:  5q35.3   HGNC cytogenetic band: 5q35.3

TBC1D9B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TBC1D9B gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M179289:  view genomic region     (about GC identifiers)

Start:
179,289,066 bp from pter      End:
179,334,859 bp from pter
Size:
45,794 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TBC9B_HUMAN, Q66K14 (See protein sequence)
Recommended Name: TBC1 domain family member 9B  
Size: 1250 amino acids; 140525 Da
Sequence caution: Sequence=AAH08919.3; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: D3DWQ5 D3DWQ6 O75163 Q53EY0 Q6MZI2 Q96H49
Alternative splicing: 2 isoforms:  Q66K14-1   Q66K14-2   

Explore the universe of human proteins at neXtProt for TBC1D9B: NX_Q66K14

Explore proteomics data for TBC1D9B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TBC1D9B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_055858.2  NP_942568.2  

    ENSEMBL proteins: 
     ENSP00000430293   ENSP00000347375   ENSP00000349291   ENSP00000428441   ENSP00000428724  
     ENSP00000429361   ENSP00000401585  

    TBC1D9B Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TBC1D9B
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TBC1D9B
    GenScript Custom Purified and Recombinant Proteins Services for TBC1D9B
    Novus Biologicals TBC1D9B Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TBC1D9B

     
    Search eBioscience for Proteins for TBC1D9B 

    TBC1D9B Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TBC1D9B
    Novus Biologicals TBC1D9B Antibody
    Abcam antibodies for TBC1D9B
    Cloud-Clone Corp. Antibodies for TBC1D9B
    Search ThermoFisher Antibodies for TBC1D9B
    LSBio Antibodies in human, mouse, rat for TBC1D9B

    TBC1D9B Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TBC1D9B
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TBC1D9B
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TBC1D9B
    Cloud-Clone Corp. CLIAs for TBC1D9B
    Search eBioscience for ELISAs for TBC1D9B 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    EFHAND: EF-hand domain containing

    4 InterPro protein domains:
     IPR011992 EF-hand-dom_pair
     IPR002048 EF_hand_dom
     IPR000195 Rab-GTPase-TBC_dom
     IPR004182 GRAM

    Graphical View of Domain Structure for InterPro Entry Q66K14

    ProtoNet protein and cluster: Q66K14

    UniProtKB/Swiss-Prot: TBC9B_HUMAN, Q66K14
    Similarity: Contains 1 EF-hand domain
    Similarity: Contains 2 GRAM domains
    Similarity: Contains 1 Rab-GAP TBC domain


    Find genes that share domains with TBC1D9B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TBC9B_HUMAN, Q66K14
    Function: May act as a GTPase-activating protein for Rab family protein(s)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005097Rab GTPase activator activity IEA--
    GO:0005509calcium ion binding IEA--
         
    Find genes that share ontologies with TBC1D9B           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TBC1D9B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TBC1D9B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TBC1D9B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TBC1D9B

    miRNA
    Products:
        
    miRTarBase miRNAs that target TBC1D9B:
    hsa-mir-769-3p (MIRT039093), hsa-let-7d-5p (MIRT032112), hsa-mir-193b-3p (MIRT041369), hsa-mir-191-3p (MIRT042393), hsa-mir-92a-3p (MIRT049656), hsa-mir-30e-3p (MIRT044119), hsa-mir-877-3p (MIRT036808), hsa-mir-940 (MIRT036620)

    Block miRNA regulation of human, mouse, rat TBC1D9B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TBC1D9B (see all 14):
    hsa-miR-3910 hsa-miR-203 hsa-miR-492 hsa-miR-128 hsa-miR-3681* hsa-miR-1205 hsa-miR-3160-3p hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidTBC1D9B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TBC1D9B
    Predesigned siRNA for gene silencing in human, mouse, rat TBC1D9B

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TBC1D9B

    Clone
    Products:
         
    OriGene clones in human, mouse for TBC1D9B (see all 12)
    OriGene ORF clones in mouse, rat for TBC1D9B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TBC1D9B (NM_015043)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TBC1D9B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TBC1D9B

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TBC1D9B
    Browse ESI BIO Cell Lines and PureStem Progenitors for TBC1D9B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBC1D9B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TBC9B_HUMAN, Q66K14: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    cytoskeleton1
    endoplasmic reticulum1
    mitochondrion1
    nucleus1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TBC1D9B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TBC1D9B
    Interactions:

        Search GeneGlobe Interaction Network for TBC1D9B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    Selected Interacting proteins for TBC1D9B (Q66K143 ENSP000003492914) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATG10Q9H0Y03I2D: score=1 
    CLN3Q132863I2D: score=1 
    GBASO753233I2D: score=1 
    MAXP612443I2D: score=1 
    GABARAPL1ENSP000002664584STRING: ENSP00000266458
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032313regulation of Rab GTPase activity ----

    Find genes that share ontologies with TBC1D9B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TBC1D9B (TBC9B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TBC1D9B gene (2 alternative transcripts): 
    NM_015043.3  NM_198868.2  

    Unigene Cluster for TBC1D9B:

    TBC1 domain family, member 9B (with GRAM domain)
    Hs.155829  [show with all ESTs]
    Unigene Representative Sequence: NM_198868
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000518085(uc003mlf.3) ENST00000519746(uc003mlg.3 uc011dgv.2)
    ENST00000355235(uc003mli.3 uc003mlj.3) ENST00000356834(uc003mlh.3)
    ENST00000522472 ENST00000521469 ENST00000520794 ENST00000524222 ENST00000522180
    ENST00000519757(uc011dgw.1) ENST00000522921 ENST00000520912(uc003mlk.1)
    ENST00000521669 ENST00000518459 ENST00000518115 ENST00000522029 ENST00000518120
    ENST00000517782
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TBC1D9B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TBC1D9B (see all 14):
    hsa-miR-3910 hsa-miR-203 hsa-miR-492 hsa-miR-128 hsa-miR-3681* hsa-miR-1205 hsa-miR-3160-3p hsa-miR-124
    SwitchGear 3'UTR luciferase reporter plasmidTBC1D9B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TBC1D9B
    Predesigned siRNA for gene silencing in human, mouse, rat TBC1D9B
    Clone
    Products:
         
    OriGene clones in human, mouse for TBC1D9B (see all 12)
    OriGene ORF clones in mouse, rat for TBC1D9B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TBC1D9B (NM_015043)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TBC1D9B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TBC1D9B
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TBC1D9B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TBC1D9B
      QuantiTect SYBR Green Assays in human, mouse, rat TBC1D9B
      QuantiFast Probe-based Assays in human, mouse, rat TBC1D9B

    Additional mRNA sequence: 

    AB014576.1 AB449893.1 AK001196.1 AK001473.1 AK026096.1 AK074791.1 AK123874.1 AK127158.1 
    AK223509.1 AK304757.1 BC000701.2 BC008919.2 BC031697.1 BC080659.1 BC110400.1 BC129994.1 
    BX641107.1 

    21 DOTS entries:

    DT.75133346  DT.91850457  DT.97857522  DT.100818040  DT.91646080  DT.95358927  DT.100673056  DT.99927384 
    DT.120865974  DT.100818039  DT.209256  DT.92448340  DT.120866062  DT.100818034  DT.75101141  DT.92448331 
    DT.100818041  DT.120865970  DT.95074588  DT.409507  DT.91902271 

    Selected AceView cDNA sequences (see all 424):

    BU784351 AW517691 BG575119 AI919415 AI380872 BM753130 BM970496 BC008919 
    BQ006015 BQ028493 H61245 CB045296 AU123617 BQ933031 AI422318 AW337818 
    CR599645 BQ959979 BM785008 AW071171 BE294448 BM820689 T32032 BG576510 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TBC1D9B (see all 9)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9a · 9b ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^ 17a · 17b ^ 18 ^ 19a · 19b ^
    SP1:                                                        -           -                                               -           -                           
    SP2:                                                                                                                    -           -                           
    SP3:                                                                                                                                -                           
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 20 ^ 21a · 21b · 21c ^ 22 ^ 23a · 23b
    SP1:        -     -                           
    SP2:  -     -     -                           
    SP3:  -     -     -                           
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for TBC1D9B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TBC1D9B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGGCTGCTCT
    TBC1D9B Expression
    About this image

    TBC1D9B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TBC1D9B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.155829
        Custom PCR Arrays for TBC1D9B
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TBC1D9B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TBC1D9B
    QuantiTect SYBR Green Assays in human, mouse, rat TBC1D9B
    QuantiFast Probe-based Assays in human, mouse, rat TBC1D9B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBC1D9B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for TBC1D9B gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tbc1d9b1 , 5 TBC1 domain family, member 9B1, 5 87.45(n)1
    92.06(a)1
      11 (30.28 cM)5
    767951  NM_029745.21  NP_084021.21 
     501313965 
    chicken
    (Gallus gallus)
    Aves TBC1D9B1 TBC1 domain family, member 9B (with GRAM domain) 75.82(n)
    80.96(a)
      416282  XM_004944952.1  XP_004945009.1 
    lizard
    (Anolis carolinensis)
    Reptilia TBC1D9B6
    TBC1 domain family, member 9B (with GRAM domain)
    79(a)
    1 ↔ 1
    2(140080127-140119273)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia AL850847.22   -- 83.12(n)    AL850847.2 
    zebrafish
    (Danio rerio)
    Actinopterygii TBC1D9B6
    TBC1 domain family, member 9B (with GRAM domain)
    76(a)
    1 ↔ 1
    14(1375404-1390307) ENSDARG00000043627


    ENSEMBL Gene Tree for TBC1D9B (if available)
    TreeFam Gene Tree for TBC1D9B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TBC1D9B gene
    TBC1D22  TBC1D8B2  SGSM32  TBC1D302  TBC1D2B2  TBC1D82  TBC1D92  
    7 SIMAP similar genes for TBC1D9B using alignment to 9 protein entries:     TBC9B_HUMAN (see all proteins):
    TBC1D9    TBC1D8B    SGSM3    FLJ00006    TBC1D8    GRTP1
    FLJ00288

    Find genes that share paralogs with TBC1D9B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TBC1D9B (see all 1237)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0361964
    A breast cancer sample4--see VAR_0361962 P Q mis40--------
    rs355329351,2
    C--174032364(+) GGCCC-/CTGTGAT 2 -- int12Minor allele frequency- CT:0.00NA CSA 4
    rs1850731,2
    C,F--174059391(+) GCGAGG/ACGGAA 2 -- ut51 ese31Minor allele frequency- A:0.00NA 2
    rs1453487061,2
    --179288835(+) ATCACA/GCCACT 2 -- ds50010--------
    rs1406919491,2
    C--179288878(+) GTCTC-/AAA   
       AAACA
    AAAAA
    2 -- ds50010--------
    rs30618301,2
    C--179288880(+) acaaa-/AAA   
       ACAAA
    GCTAC
    2 -- ds50011Minor allele frequency- AAAACAAA:0.00NA 2
    rs1141439341,2
    F--179288949(+) GAGATA/GTACAA 2 -- ds50011Minor allele frequency- G:0.04WA 118
    rs1379603931,2
    --179289006(+) CAGCCA/GCCTGG 2 -- ds50010--------
    rs1494609631,2
    C--179289148(+) AATCAC/TAGGTA 2 -- ut310--------
    rs1922051,2
    C,H--179289222(-) ccagaC/Acccca 2 -- ut31 ese31Minor allele frequency- A:0.01NS 180

    HapMap Linkage Disequilibrium report for TBC1D9B (179289066 - 179334859 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for TBC1D9B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv4887CNV Deletion18987735
    esv2731312CNV Deletion23290073
    esv990502CNV Deletion20482838
    nsv327239CNV Loss16902084
    nsv883270CNV Loss21882294
    nsv883286CNV Loss21882294
    nsv823362CNV Loss20364138
    nsv469579CNV Loss16826518
    nsv483062CNV Loss15286789
    dgv6400n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TBC1D9B
    DNA2.0 Custom Variant and Variant Library Synthesis for TBC1D9B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TBC1D9B gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with TBC1D9B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9734811)1, 2, 3 Ishikawa K.... Ohara O. (DNA Res. 1998)
    2. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    3. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    4. Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers. (PubMed id 22354992)1 Popovic D....Dikic I. (Mol. Cell. Biol. 2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    9. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 23061 HGNC: 29097 AceView: KIAA0676 Ensembl:ENSG00000197226 euGenes: HUgn23061
    ECgene: TBC1D9B H-InvDB: TBC1D9B

    (According to HUGE)
    About This Section

    TryGeneCards Plus
    HUGE: KIAA0676

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TBC1D9B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TBC1D9B gene:
    Search GeneIP for patents involving TBC1D9B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TBC1D9B  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for TBC1D9B  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TBC1D9B  
     OriGene qSTAR qPCR primer pairs in human, mouse for TBC1D9B   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TBC1D9B   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TBC1D9B   OriGene Custom Protein Services for TBC1D9B  

     
     
     Block miRNA regulation of human, mouse, rat TBC1D9B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TBC1D9B
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TBC1D9B Predesigned siRNA for gene silencing in human, mouse, rat TBC1D9B
     QuantiFast Probe-based Assays in human, mouse, rat TBC1D9B QuantiTect SYBR Green Assays in human, mouse, rat TBC1D9B
     Custom PCR Arrays for TBC1D9B Search Chromatin IP Primers for TBC1D9B
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TBC1D9B  Search GeneGlobe Interaction Network for TBC1D9B
     Regulatory tfbs in TBC1D9B promoter
     GenScript Custom Purified and Recombinant Proteins Services for TBC1D9B GenScript cDNA clones with any tag delivered in your preferred vector for TBC1D9B
     GenScript Custom Assay Services for TBC1D9B GenScript Custom overexpressing Cell Line Services for TBC1D9B
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TBC1D9B (TBC9B)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TBC1D9B antibodies
     TBC1D9B lysates
     Antibodies for TBC1D9B
     See all of Abcam's Antibodies, Kits and Proteins for TBC1D9B
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TBC1D9B
     Antibodies for TBC1D9B
     ELISAs for TBC1D9B
     CLIAs for TBC1D9B



     Browse ESI BIO Cell Lines and PureStem Progenitors for TBC1D9B
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TBC1D9B
     SwitchGear 3'UTR luciferase reporter plasmids for TBC1D9B
     SwitchGear Promoter luciferase reporter plasmids for TBC1D9B
     Search ThermoFisher Antibodies for TBC1D9B
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TBC1D9B
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TBC1D9B
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TBC1D9B
     LSBio Antibodies in human, mouse, rat for TBC1D9B
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for TBC1D9B
      Search eBioscience for proteins for TBC1D9B
      Search eBioscience for elisas for TBC1D9B
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TBC1D9B gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4