Aliases for TBC1D8B Gene
External Ids for TBC1D8B Gene
This gene encodes a protein with a TBC (Tre-2/Bub2/CDC16) domain. Some mammalian proteins with this domain have been shown to function as Rab-GAPs by binding to specific Rab proteins and affecting their GTPase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
GeneCards Summary for TBC1D8B Gene
TBC1D8B (TBC1 Domain Family, Member 8B (With GRAM Domain)) is a Protein Coding gene. Among its related pathways are Clathrin derived vesicle budding and Clathrin derived vesicle budding. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is TBC1D30.
UniProtKB/Swiss-Prot for TBC1D8B Gene
May act as a GTPase-activating protein for Rab family protein(s)