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Aliases for TBC1D29 Gene

Aliases for TBC1D29 Gene

  • TBC1 Domain Family Member 29 2 3 5
  • TBC1 Domain Family, Member 29 2

External Ids for TBC1D29 Gene

Previous GeneCards Identifiers for TBC1D29 Gene

  • GC17P025910
  • GC17P028886
  • GC17P025096

Summaries for TBC1D29 Gene

GeneCards Summary for TBC1D29 Gene

TBC1D29 (TBC1 Domain Family Member 29) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TBC1D29 Gene

Genomics for TBC1D29 Gene

Regulatory Elements for TBC1D29 Gene

Genomic Location for TBC1D29 Gene

Chromosome:
17
Start:
30,557,112 bp from pter
End:
30,565,667 bp from pter
Size:
8,556 bases
Orientation:
Plus strand

Genomic View for TBC1D29 Gene

Genes around TBC1D29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TBC1D29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TBC1D29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TBC1D29 Gene

Proteins for TBC1D29 Gene

  • Protein details for TBC1D29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UFV1-TBC29_HUMAN
    Recommended name:
    Putative TBC1 domain family member 29
    Protein Accession:
    Q9UFV1

    Protein attributes for TBC1D29 Gene

    Size:
    150 amino acids
    Molecular mass:
    16280 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TBC1D29 Gene

Proteomics data for TBC1D29 Gene at MOPED

Post-translational modifications for TBC1D29 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TBC1D29 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TBC1D29 Gene

Domains & Families for TBC1D29 Gene

Protein Domains for TBC1D29 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TBC1D29 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UFV1

UniProtKB/Swiss-Prot:

TBC29_HUMAN :
  • Contains 1 Rab-GAP TBC domain.
Domain:
  • Contains 1 Rab-GAP TBC domain.
genes like me logo Genes that share domains with TBC1D29: view

No data available for Gene Families for TBC1D29 Gene

Function for TBC1D29 Gene

genes like me logo Genes that share phenotypes with TBC1D29: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TBC1D29 Gene

Localization for TBC1D29 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TBC1D29 Gene

Pathways & Interactions for TBC1D29 Gene

SuperPathways for TBC1D29 Gene

No Data Available

Interacting Proteins for TBC1D29 Gene

Gene Ontology (GO) - Biological Process for TBC1D29 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TBC1D29 Gene

Drugs & Compounds for TBC1D29 Gene

No Compound Related Data Available

Transcripts for TBC1D29 Gene

mRNA/cDNA for TBC1D29 Gene

(2) REFSEQ mRNAs :
(3) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TBC1D29 Gene

No ASD Table

Relevant External Links for TBC1D29 Gene

GeneLoc Exon Structure for
TBC1D29
ECgene alternative splicing isoforms for
TBC1D29

Expression for TBC1D29 Gene

mRNA expression in normal human tissues for TBC1D29 Gene

mRNA differential expression in normal tissues according to GTEx for TBC1D29 Gene

This gene is overexpressed in Testis (x26.9).

SOURCE GeneReport for Unigene cluster for TBC1D29 Gene Hs.241421

genes like me logo Genes that share expression patterns with TBC1D29: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TBC1D29 Gene

Orthologs for TBC1D29 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TBC1D29 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC101059380 35
  • 90.88 (n)
  • 85.85 (a)
TBC1D29 36
  • 91 (a)
OneToOne
Species with no ortholog for TBC1D29:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TBC1D29 Gene

ENSEMBL:
Gene Tree for TBC1D29 (if available)
TreeFam:
Gene Tree for TBC1D29 (if available)

Paralogs for TBC1D29 Gene

(9) SIMAP similar genes for TBC1D29 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TBC1D29: view

No data available for Paralogs for TBC1D29 Gene

Variants for TBC1D29 Gene

Sequence variations from dbSNP and Humsavar for TBC1D29 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs170053 -- 30,566,065(+) TCTGC(C/T)TTGAT downstream-variant-500B
rs216455 -- 30,563,185(+) GCCTG(C/T)TCTCC intron-variant
rs216456 -- 30,564,478(+) TGTGC(A/G)TGCAC utr-variant-3-prime
rs216457 -- 30,565,825(+) CACTA(A/G)TATCA downstream-variant-500B
rs216458 -- 30,566,010(+) CTTCT(A/G)AAGGT downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for TBC1D29 Gene

Variant ID Type Subtype PubMed ID
nsv515870 CNV Gain 19592680
dgv3138n71 CNV Gain 21882294
esv29095 CNV Gain 19812545
nsv827943 CNV Gain 20364138
esv32561 CNV Gain 17666407
nsv908047 CNV Gain 21882294
nsv471394 CNV Duplication 19718026

Variation tolerance for TBC1D29 Gene

Residual Variation Intolerance Score: 74.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.37; 8.21% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TBC1D29 Gene

HapMap Linkage Disequilibrium report
TBC1D29

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TBC1D29 Gene

Disorders for TBC1D29 Gene

Relevant External Links for TBC1D29

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TBC1D29

No disorders were found for TBC1D29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TBC1D29 Gene

Publications for TBC1D29 Gene

  1. GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. (PMID: 12618308) Bernards A. (Biochim. Biophys. Acta 2003) 2 3 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TBC1D29 Gene

Sources for TBC1D29 Gene

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