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Aliases for TBC1D29 Gene

Aliases for TBC1D29 Gene

  • TBC1 Domain Family Member 29 2 3 5
  • TBC1 Domain Family, Member 29 2

External Ids for TBC1D29 Gene

Previous GeneCards Identifiers for TBC1D29 Gene

  • GC17P025910
  • GC17P028886
  • GC17P025096

Summaries for TBC1D29 Gene

GeneCards Summary for TBC1D29 Gene

TBC1D29 (TBC1 Domain Family Member 29) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TBC1D29 Gene

Genomics for TBC1D29 Gene

Regulatory Elements for TBC1D29 Gene

Enhancers for TBC1D29 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G029638 2 FANTOM5 Ensembl ENCODE dbSUPER 10.1 -914.6 -914640 8.2 HDGF PKNOX1 ARNT SIN3A FEZF1 ZNF2 ZBTB7B ZNF766 ZNF143 FOS CORO6 LRRC37BP1 SMURF2P1 ANKRD13B ENSG00000252657 TBC1D29 SH3GL1P2 TAOK1 ENSG00000239129 LOC101927018
GH17G029586 1.7 FANTOM5 ENCODE dbSUPER 10.1 -966.5 -966510 8.4 HDGF PKNOX1 CREB3L1 ZFP64 ARID4B SIN3A DMAP1 FEZF1 ZNF2 YY1 TP53I13 CORO6 ANKRD13B LRRC37BP1 ENSG00000258472 TBC1D29 EFCAB5 GIT1 ENSG00000264647
GH17G031315 1.2 ENCODE dbSUPER 10.1 +762.3 762310 7.3 PKNOX1 SIN3A CBX5 ZNF143 FOS ZNF202 JUNB ZNF623 TBX21 ZNF518A SUZ12 UTP6 SMURF2P1 ENSG00000266490 LRRC37BP1 SUZ12P1 TBC1D29 SH3GL1P2 EVI2A OMG
GH17G030343 1.9 FANTOM5 Ensembl ENCODE dbSUPER 6.3 -211.9 -211921 4.0 PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A DMAP1 YY1 SLC30A9 ZNF766 BLMH RNU6-1267P TBC1D29 CPD EFCAB5 NSRP1 GC17M030345 ENSG00000207132 GC17P030362
GH17G029598 1.1 ENCODE dbSUPER 10.1 -959.5 -959500 1.2 HDGF ZNF133 ZNF76 KLF17 GLIS2 ZNF263 ZBTB11 ZNF426 ZNF781 ZNF518A CORO6 ANKRD13B LRRC37BP1 TBC1D29 GIT1 ENSG00000264007
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TBC1D29 on UCSC Golden Path with GeneCards custom track

Genomic Location for TBC1D29 Gene

Chromosome:
17
Start:
30,557,112 bp from pter
End:
30,565,667 bp from pter
Size:
8,556 bases
Orientation:
Plus strand

Genomic View for TBC1D29 Gene

Genes around TBC1D29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TBC1D29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TBC1D29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TBC1D29 Gene

Proteins for TBC1D29 Gene

  • Protein details for TBC1D29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UFV1-TBC29_HUMAN
    Recommended name:
    Putative TBC1 domain family member 29
    Protein Accession:
    Q9UFV1

    Protein attributes for TBC1D29 Gene

    Size:
    150 amino acids
    Molecular mass:
    16280 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TBC1D29 Gene

Post-translational modifications for TBC1D29 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TBC1D29 Gene

No data available for DME Specific Peptides for TBC1D29 Gene

Domains & Families for TBC1D29 Gene

Protein Domains for TBC1D29 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TBC1D29 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TBC1D29: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TBC1D29 Gene

Function for TBC1D29 Gene

genes like me logo Genes that share phenotypes with TBC1D29: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TBC1D29 Gene

Localization for TBC1D29 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TBC1D29 Gene

Pathways & Interactions for TBC1D29 Gene

SuperPathways for TBC1D29 Gene

No Data Available

Interacting Proteins for TBC1D29 Gene

Gene Ontology (GO) - Biological Process for TBC1D29 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TBC1D29 Gene

Transcripts for TBC1D29 Gene

mRNA/cDNA for TBC1D29 Gene

(2) REFSEQ mRNAs :
(3) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TBC1D29 Gene

No ASD Table

Relevant External Links for TBC1D29 Gene

GeneLoc Exon Structure for
TBC1D29
ECgene alternative splicing isoforms for
TBC1D29

Expression for TBC1D29 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TBC1D29 Gene

mRNA differential expression in normal tissues according to GTEx for TBC1D29 Gene

This gene is overexpressed in Testis (x26.9).

NURSA nuclear receptor signaling pathways regulating expression of TBC1D29 Gene:

TBC1D29

SOURCE GeneReport for Unigene cluster for TBC1D29 Gene:

Hs.241421
genes like me logo Genes that share expression patterns with TBC1D29: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TBC1D29 Gene

Orthologs for TBC1D29 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TBC1D29 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TBC1D29 35
  • 91 (a)
OneToOne
LOC101059380 34
  • 90.88 (n)
Species where no ortholog for TBC1D29 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TBC1D29 Gene

ENSEMBL:
Gene Tree for TBC1D29 (if available)
TreeFam:
Gene Tree for TBC1D29 (if available)

Paralogs for TBC1D29 Gene

No data available for Paralogs for TBC1D29 Gene

Variants for TBC1D29 Gene

Sequence variations from dbSNP and Humsavar for TBC1D29 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000096254 -- 30,559,928(+) TGGGG(A/G)CCCTG intron-variant
rs1001645780 -- 30,557,851(+) ATAGG(A/G)GCCAC upstream-variant-2KB
rs1004544346 -- 30,561,862(+) CCTGA(A/C)TTTTT intron-variant
rs1004577267 -- 30,561,600(+) ACATT(G/T)GGGTT intron-variant
rs1005626496 -- 30,564,610(+) TGCAG(A/G)AAGTT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for TBC1D29 Gene

Variant ID Type Subtype PubMed ID
dgv3138n100 CNV gain 25217958
esv29095 CNV gain 19812545
esv32561 CNV gain 17666407
esv3640341 CNV gain 21293372
nsv1060557 CNV gain 25217958
nsv1064611 CNV gain 25217958
nsv471394 CNV gain 19718026
nsv515870 CNV gain 19592680
nsv827943 CNV gain 20364138
nsv978404 CNV duplication 23825009

Variation tolerance for TBC1D29 Gene

Residual Variation Intolerance Score: 74.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.37; 8.21% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TBC1D29 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TBC1D29

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TBC1D29 Gene

Disorders for TBC1D29 Gene

Relevant External Links for TBC1D29

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TBC1D29

No disorders were found for TBC1D29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TBC1D29 Gene

Publications for TBC1D29 Gene

  1. GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. (PMID: 12618308) Bernards A. (Biochim. Biophys. Acta 2003) 2 3 64
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for TBC1D29 Gene

Sources for TBC1D29 Gene

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