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Aliases for TBC1D29 Gene

Aliases for TBC1D29 Gene

  • TBC1 Domain Family Member 29 2 3 5
  • TBC1 Domain Family, Member 29 2

External Ids for TBC1D29 Gene

Previous GeneCards Identifiers for TBC1D29 Gene

  • GC17P025910
  • GC17P028886
  • GC17P025096

Summaries for TBC1D29 Gene

GeneCards Summary for TBC1D29 Gene

TBC1D29 (TBC1 Domain Family Member 29) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TBC1D29 Gene

Genomics for TBC1D29 Gene

Regulatory Elements for TBC1D29 Gene

Enhancers for TBC1D29 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17F030818 0.2 ENCODE 12.1 +265.7 265671 8.4 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 ZNF2 YY1 SLC30A9 ZNF207 SUZ12P1 ENSG00000265289 LOC101927093 ENSG00000214719 ENSG00000263567 TBC1D29 LRRC37BP1 CRLF3 ENSG00000276250
GH17F029743 1 Ensembl ENCODE 12 -812.3 -812281 1.8 FEZF1 ZNF2 SLC30A9 ZNF302 ZNF548 ZNF202 YY2 TSHZ1 ZNF488 MIER3 SH3GL1P2 NUFIP2 CORO6 ENSG00000265289 ENSG00000264647 ENSG00000266111 NDUFS5P7 ENSG00000214719 LOC101927093 LOC105371715
GH17F030343 1.2 FANTOM5 Ensembl ENCODE 6.3 -211.9 -211908 4.0 PKNOX1 ATF1 MLX ARID4B SIN3A DMAP1 ZNF48 YY1 SLC30A9 GATA2 BLMH RNU6-1267P TBC1D29 CPD EFCAB5 NSRP1 ENSG00000207132 GC17M030345 GC17P030362
GH17F030550 1.4 Ensembl ENCODE 5.7 -6.1 -6112 1.6 KLF1 CBX3 ZNF223 MAX CEBPG EBF1 ZFHX2 POLR2A EED NFE2 CORO6 ENSG00000259928 TBC1D29 CPD ENSG00000263860 ALOX12P1
GH17F030551 0.7 FANTOM5 5.7 -5.2 -5221 0.1 HDGF PKNOX1 NFYC SIN3A ZEB2 ZBTB33 TBC1D29 ENSG00000279431 LOC100420311
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TBC1D29 on UCSC Golden Path with GeneCards custom track

Genomic Location for TBC1D29 Gene

Chromosome:
17
Start:
30,557,112 bp from pter
End:
30,565,667 bp from pter
Size:
8,556 bases
Orientation:
Plus strand

Genomic View for TBC1D29 Gene

Genes around TBC1D29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TBC1D29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TBC1D29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TBC1D29 Gene

Proteins for TBC1D29 Gene

  • Protein details for TBC1D29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UFV1-TBC29_HUMAN
    Recommended name:
    Putative TBC1 domain family member 29
    Protein Accession:
    Q9UFV1

    Protein attributes for TBC1D29 Gene

    Size:
    150 amino acids
    Molecular mass:
    16280 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TBC1D29 Gene

Post-translational modifications for TBC1D29 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TBC1D29 Gene

No data available for DME Specific Peptides for TBC1D29 Gene

Domains & Families for TBC1D29 Gene

Protein Domains for TBC1D29 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TBC1D29 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9UFV1

UniProtKB/Swiss-Prot:

TBC29_HUMAN :
  • Contains 1 Rab-GAP TBC domain.
Domain:
  • Contains 1 Rab-GAP TBC domain.
genes like me logo Genes that share domains with TBC1D29: view

No data available for Gene Families for TBC1D29 Gene

Function for TBC1D29 Gene

genes like me logo Genes that share phenotypes with TBC1D29: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TBC1D29 Gene

Localization for TBC1D29 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TBC1D29 Gene

Pathways & Interactions for TBC1D29 Gene

SuperPathways for TBC1D29 Gene

No Data Available

Interacting Proteins for TBC1D29 Gene

Gene Ontology (GO) - Biological Process for TBC1D29 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TBC1D29 Gene

Transcripts for TBC1D29 Gene

mRNA/cDNA for TBC1D29 Gene

(2) REFSEQ mRNAs :
(3) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TBC1D29 Gene

No ASD Table

Relevant External Links for TBC1D29 Gene

GeneLoc Exon Structure for
TBC1D29
ECgene alternative splicing isoforms for
TBC1D29

Expression for TBC1D29 Gene

mRNA expression in normal human tissues for TBC1D29 Gene

mRNA differential expression in normal tissues according to GTEx for TBC1D29 Gene

This gene is overexpressed in Testis (x26.9).

NURSA nuclear receptor signaling pathways regulating expression of TBC1D29 Gene:

TBC1D29

SOURCE GeneReport for Unigene cluster for TBC1D29 Gene:

Hs.241421
genes like me logo Genes that share expression patterns with TBC1D29: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TBC1D29 Gene

Orthologs for TBC1D29 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for TBC1D29 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TBC1D29 35
  • 91 (a)
OneToOne
LOC101059380 34
  • 90.88 (n)
Species where no ortholog for TBC1D29 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TBC1D29 Gene

ENSEMBL:
Gene Tree for TBC1D29 (if available)
TreeFam:
Gene Tree for TBC1D29 (if available)

Paralogs for TBC1D29 Gene

No data available for Paralogs for TBC1D29 Gene

Variants for TBC1D29 Gene

Sequence variations from dbSNP and Humsavar for TBC1D29 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs111540387 -- 30,557,739(+) GCTAC(C/T)AAAGT upstream-variant-2KB
rs111780165 -- 30,560,116(+) CATCA(A/G)GACAA splice-acceptor-variant
rs112002741 -- 30,558,112(+) AGCTC(A/C)CTGCT upstream-variant-2KB
rs112192061 -- 30,559,338(+) GGAGA(C/T)GACCA upstream-variant-2KB
rs112409387 -- 30,564,054(+) ACAGC(A/C)TCTCA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TBC1D29 Gene

Variant ID Type Subtype PubMed ID
dgv3138n100 CNV gain 25217958
esv29095 CNV gain 19812545
esv32561 CNV gain 17666407
esv3640341 CNV gain 21293372
nsv1060557 CNV gain 25217958
nsv1064611 CNV gain 25217958
nsv471394 CNV gain 19718026
nsv515870 CNV gain 19592680
nsv827943 CNV gain 20364138
nsv978404 CNV duplication 23825009

Variation tolerance for TBC1D29 Gene

Residual Variation Intolerance Score: 74.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.37; 8.21% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TBC1D29 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TBC1D29

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TBC1D29 Gene

Disorders for TBC1D29 Gene

Relevant External Links for TBC1D29

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TBC1D29

No disorders were found for TBC1D29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TBC1D29 Gene

Publications for TBC1D29 Gene

  1. GAPs galore! A survey of putative Ras superfamily GTPase activating proteins in man and Drosophila. (PMID: 12618308) Bernards A. (Biochim. Biophys. Acta 2003) 2 3 64
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for TBC1D29 Gene

Sources for TBC1D29 Gene

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