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TAX1BP3 Gene

protein-coding   GIFtS: 53
GCID: GC17M003566

Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein...

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tax1 (Human T-Cell Leukemia Virus Type I) Binding Protein 31 2     TIP-12 3
Tax Interaction Protein 11 2 3     Tax1-Binding Protein 32
Glutaminase-Interacting Protein 32 3     TIP13
Tax-Interacting Protein 12 3     

External Ids:    HGNC: 306841   Entrez Gene: 308512   Ensembl: ENSG000002139777   UniProtKB: O149073   

Export aliases for TAX1BP3 gene to outside databases

Previous GC identifers: GC17M003773 GC17M003512 GC17M003457


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TAX1BP3 Gene:
TAX1BP3 (Tax1 (human T-cell leukemia virus type I) binding protein 3) is a protein-coding gene. Diseases associated with TAX1BP3 include nephropathic cystinosis, and cystinosis. GO annotations related to this gene include beta-catenin binding and protein C-terminus binding.

UniProtKB/Swiss-Prot: TX1B3_HUMAN, O14907
Function: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds
CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding,
and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in
activation of CDC42 by the viral protein HPV16 E6

Gene Wiki entry for TAX1BP3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000017.11  NC_018928.2  NT_010718.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the TAX1BP3 gene promoter:
         AhR   E2F-4   E2F-3a   E2F-5   Sp1   IRF-1   E2F-2   E2F   E2F-1   ARP-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTAX1BP3 promoter sequence
   Search Chromatin IP Primers for TAX1BP3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TAX1BP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13   Ensembl cytogenetic band:  17p13.2   HGNC cytogenetic band: 17p13

TAX1BP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAX1BP3 gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M003566:  view genomic region     (about GC identifiers)

Start:
3,566,187 bp from pter      End:
3,571,976 bp from pter
Size:
5,790 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TX1B3_HUMAN, O14907 (See protein sequence)
Recommended Name: Tax1-binding protein 3  
Size: 124 amino acids; 13735 Da
Subunit: Interacts (via its PDZ domain) with GLS2. Interacts (via its PDZ domain) with RTKN (via the C-terminal
region); this interaction facilitates Rho-mediated activation of the FOS serum response element (SRE). Interacts
(via its PDZ domain) with CTNNB1; this interaction inhibits the transcriptional activity of CTNNB1. Interacts
with HTLV-1 TAX protein. Interacts (via PDZ domain) with ARHGEF16. Interacts (via PDZ domain) with KCNJ4 (via
C-terminus). Competes with LIN7A for KCNJ4 binding
Sequence caution: Sequence=AAF43104.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Selected PDB 3D structures from and Proteopedia for TAX1BP3 (see all 7):
2KG2 (3D)        2L4S (3D)        2L4T (3D)        2VZ5 (3D)        3GJ9 (3D)        3SFJ (3D)    
Secondary accessions: B2RD53 D3DTJ6 Q7LCQ4

Explore the universe of human proteins at neXtProt for TAX1BP3: NX_O14907

Explore proteomics data for TAX1BP3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys116
  • Modification sites at PhosphoSitePlus

  • See TAX1BP3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001191627.1  NP_055419.1  

    ENSEMBL proteins: 
     ENSP00000225525  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR017268 Tax1-binding_p3
     IPR001478 PDZ

    Graphical View of Domain Structure for InterPro Entry O14907

    ProtoNet protein and cluster: O14907

    1 Blocks protein domain: IPB001478 PDZ/DHR/GLGF domain

    UniProtKB/Swiss-Prot: TX1B3_HUMAN, O14907
    Similarity: Contains 1 PDZ (DHR) domain


    TAX1BP3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TX1B3_HUMAN, O14907
    Function: May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds
    CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding,
    and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in
    activation of CDC42 by the viral protein HPV16 E6

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI10940294
    GO:0008013beta-catenin binding IEA--
    GO:0008022protein C-terminus binding IPI16855024
         
    TAX1BP3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TAX1BP3:
     Decreased Hepatitis C virus re 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TAX1BP3
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    miRNA
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    miRTarBase miRNAs that target TAX1BP3:
    hsa-mir-26b-5p (MIRT028783), hsa-mir-92a-3p (MIRT049449), hsa-mir-324-5p (MIRT043024), hsa-mir-124-3p (MIRT022204)

    Block miRNA regulation of human, mouse, rat TAX1BP3 using miScript Target Protectors
    8 qRT-PCR Assays for microRNAs that regulate TAX1BP3:
    hsa-miR-4324 hsa-miR-4303 hsa-miR-1237 hsa-miR-922 hsa-miR-214 hsa-miR-544b hsa-miR-298 hsa-miR-761
    SwitchGear 3'UTR luciferase reporter plasmidTAX1BP3 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TX1B3_HUMAN, O14907: Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
    Note=Recruited to the cell membrane by interaction with membrane proteins
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    plasma membrane5
    cytosol3
    mitochondrion1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm NAS10940294
    GO:0005886plasma membrane IEA--
    GO:0070062extracellular vesicular exosome IDA19056867

    TAX1BP3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TAX1BP3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Wnt signaling pathway (KEGG)
    Wnt Signaling Pathway NetPath0.37

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for TAX1BP3
        Cellular Transformation by HTLV1

    1 BioSystems Pathway for TAX1BP3
        Wnt Signaling Pathway NetPath


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TAX1BP3
    Interactions:

        GeneGlobe Interaction Network for TAX1BP3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for TAX1BP3 (O149071, 2, 3 ENSP000002255254) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RTKNQ9BST93, ENSP000002724304I2D: score=2 STRING: ENSP00000272430
    CNTN2Q022463, ENSP000003306334I2D: score=1 STRING: ENSP00000330633
    GLS2Q9UI323, ENSP000003104474I2D: score=1 STRING: ENSP00000310447
    TRIM29Q141343, ENSP000003431294I2D: score=1 STRING: ENSP00000343129
    CTNNB1P352223, ENSP000003444564I2D: score=5 STRING: ENSP00000344456
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007266Rho protein signal transduction IDA10940294
    GO:0008285negative regulation of cell proliferation IEA--
    GO:0016055Wnt signaling pathway IEA--
    GO:0030111regulation of Wnt signaling pathway ----
    GO:0030178negative regulation of Wnt signaling pathway ISS--

    TAX1BP3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TAX1BP3 (TX1B3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TAX1BP3 gene (2 alternative transcripts): 
    NM_001204698.1  NM_014604.3  

    Unigene Cluster for TAX1BP3:

    Tax1 (human T-cell leukemia virus type I) binding protein 3
    Hs.12956  [show with all ESTs]
    Unigene Representative Sequence: BM809975
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000225525(uc002fwc.3 uc021tnt.1 uc002fwe.1)
    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8 qRT-PCR Assays for microRNAs that regulate TAX1BP3:
    hsa-miR-4324 hsa-miR-4303 hsa-miR-1237 hsa-miR-922 hsa-miR-214 hsa-miR-544b hsa-miR-298 hsa-miR-761
    SwitchGear 3'UTR luciferase reporter plasmidTAX1BP3 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector (see all 2): TAX1BP3 (NM_001204698)
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      QuantiTect SYBR Green Assays in human, mouse, rat TAX1BP3
      QuantiFast Probe-based Assays in human, mouse, rat TAX1BP3

    Additional mRNA sequence: 

    AF028823.2 AF234997.1 AF277318.1 AK315408.1 BC023980.1 U90913.1 

    21 DOTS entries:

    DT.446099  DT.100872453  DT.100762721  DT.100872447  DT.95368959  DT.100872448  DT.102839774  DT.100872443 
    DT.91683429  DT.100872454  DT.100662227  DT.91704958  DT.120962859  DT.120962937  DT.91864652  DT.95368946 
    DT.95368961  DT.91770361  DT.91783155  DT.95368962  DT.97764684 

    Selected AceView cDNA sequences (see all 489):

    BU856701 AI640789 CR607043 AA627384 CR615413 AI648478 BQ225278 BI755442 
    CR595900 AI149950 BQ227997 AI087176 BI517299 BM888113 CR602958 CB154980 
    CR609956 CR591740 BM788342 CR606404 AW080323 CR606577 BE326458 AA278732 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TAX1BP3 expression in normal human tissues (normalized intensities)      TAX1BP3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGTCCTAGC
    TAX1BP3 Expression
    About this image


    TAX1BP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Trophoblast (Extraembryonic Tissues)
             Mural Trophectoderm Cells Mural Trophectoderm
     
     Limb (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Zeugopod
     
     Bone (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Zeugopod
     
     Cartilage (Muscoskeletal System)
             Prechondrocytic Mesenchymal Cells Zeugopod
    TAX1BP3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TAX1BP3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.12956

    UniProtKB/Swiss-Prot: TX1B3_HUMAN, O14907
    Tissue specificity: Ubiquitous. Detected in brain, heart, kidney, lung, small intestine and skeletal muscle.
    Detected in various cell lines including HeLa. Weakly expressed in peripheral blood leukocytes

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAX1BP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TAX1BP3 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tax1bp31 , 5 Tax1 (human T cell leukemia virus type I) binding protein more1, 5 90.05(n)1
    99.19(a)1
      11 (45.25 cM)5
    762811  NM_029564.21  NP_083840.11 
     731770835 
    chicken
    (Gallus gallus)
    Aves TAX1BP31 Tax1 (human T-cell leukemia virus type I) binding protein more 82.53(n)
    94.35(a)
      417605  XM_415850.4  XP_415850.1 
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia MGC762482 hypothetical protein MGC76248 77.38(n)    BC063221.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.47882 Danio rerio mRNA similar to Tax interaction protein more 79.67(n)    BC042322.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG34026
    --
    40(a)
    1 ↔ 1
    3L(651542-652881)
    worm
    (Caenorhabditis elegans)
    Secernentea C45G9.76
    Protein C45G9.7 (C45G9.7) mRNA, complete cds
    40(a)
    1 ↔ 1
    III(5046169-5047142) WBGene00016678


    ENSEMBL Gene Tree for TAX1BP3 (if available)
    TreeFam Gene Tree for TAX1BP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TAX1BP3 gene
    10 SIMAP similar genes for TAX1BP3 using alignment to 1 protein entry:     TX1B3_HUMAN:
    PDZRN3    LRRC7    SCRIB    DLG3    DLG2    PDZRN4
    ERBB2IP    DLG1    DLG4    FRMPD2

    TAX1BP3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for TAX1BP3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv1947CNV Insertion18451855
    nsv833342CNV Loss17160897
    nsv907569CNV Loss21882294
    dgv358n27CNV Loss19166990
    nsv907565CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TAX1BP3
    DNA2.0 Custom Variant and Variant Library Synthesis for TAX1BP3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    9 diseases for TAX1BP3:    About MalaCards
    nephropathic cystinosis    cystinosis    t-cell leukemia    intrahepatic cholangiocarcinoma
    cholangiocarcinoma    leukemia    malignant glioma    colorectal cancer
    breast cancer


    TAX1BP3 for disorders           About GeneDecksing


    Export disorders for TAX1BP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TAX1BP3 gene, integrated from 10 sources (see all 47):
    (articles sorted by number of sources associating them with TAX1BP3)
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    1. The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion. (PubMed id 10673275)1, 2, 3 Touchman J.W....Green E.D. (Genome Res. 2000)
    2. The HPV16 E6 binding protein Tip-1 interacts with ARHGEF16, which activates Cdc42. (PubMed id 21139582)1, 2 Oliver A.W....Hampson I.N. (Br. J. Cancer 2011)
    3. Molecular mechanism of inward rectifier potassium channel 2.3 regulation by tax-interacting protein-1. (PubMed id 19635485)1, 2 Yan X....Long J. (J. Mol. Biol. 2009)
    4. TIP-1 has PDZ scaffold antagonist activity. (PubMed id 16855024)1, 2 Alewine C.... Welling P.A. (Mol. Biol. Cell 2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The C-terminus of human glutaminase L mediates association with PDZ domain-containing proteins. (PubMed id 11163757)1, 2 Olalla L.... Marquez J. (FEBS Lett. 2001)
    8. The PDZ protein TIP-1 interacts with the Rho effector rhotekin and is involved in Rho signaling to the serum response element. (PubMed id 10940294)1, 2 Reynaud C.... Jalinot P. (J. Biol. Chem. 2000)
    9. The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins. (PubMed id 9482110)1, 2 Rousset R.... Jalinot P. (Oncogene 1998)
    10. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (Anal. Biochem. 1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 30851 HGNC: 30684 AceView: TAX1BP3 Ensembl:ENSG00000213977 euGenes: HUgn30851
    ECgene: TAX1BP3 H-InvDB: TAX1BP3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TAX1BP3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TAX1BP3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TAX1BP3 gene:
    Search GeneIP for patents involving TAX1BP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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