Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TATDN3 Gene

protein-coding   GIFtS: 47
GCID: GC01P212965

TatD DNase Domain Containing 3

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
TatD DNase Domain Containing 31 2
Putative Deoxyribonuclease TATDN32
EC 3.1.21.-3
EC 3.1.218

External Ids:    HGNC: 270101   Entrez Gene: 1283872   Ensembl: ENSG000002037057   UniProtKB: Q17R313   

Export aliases for TATDN3 gene to outside databases

Previous GC identifers: GC01P209354 GC01P211031 GC01P183641


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TATDN3 Gene:
TATDN3 (TatD DNase domain containing 3) is a protein-coding gene. Diseases associated with TATDN3 include intrahepatic cholangiocarcinoma, and cholangiocarcinoma. GO annotations related to this gene include endodeoxyribonuclease activity, producing 5'-phosphomonoesters.

UniProtKB/Swiss-Prot: TATD3_HUMAN, Q17R31
Function: Putative deoxyribonuclease




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_004487.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the TATDN3 gene promoter:
         AML1a   FOXO3   XBP-1   FOXO3b   RORalpha1   POU2F1   POU2F1a   FOXO4   Cart-1   FOXO3a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TATDN3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TATDN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q32.3   Ensembl cytogenetic band:  1q32.3   HGNC cytogenetic band: 1q32.3

TATDN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TATDN3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P212965:  view genomic region     (about GC identifiers)

Start:
212,965,170 bp from pter      End:
212,990,167 bp from pter
Size:
24,998 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TATD3_HUMAN, Q17R31 (See protein sequence)
Recommended Name: Putative deoxyribonuclease TATDN3  
Size: 274 amino acids; 30333 Da
Cofactor: Binds 2 divalent metal cations per subunit
Sequence caution: Sequence=AAH48115.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for TATDN3:
2Y1H (3D)    
Secondary accessions: A6NGS3 B7Z1C1 B7Z978 B7ZLQ6 E9PJE5 E9PNH3 G3V151 Q4G0L1
Alternative splicing: 5 isoforms:  Q17R31-1   Q17R31-2   Q17R31-3   Q17R31-4   Q17R31-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TATDN3: NX_Q17R31

Explore proteomics data for TATDN3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys123
  • 2 DME Specific Peptides for TATDN3 (Q17R31)
     AIGEVGL  PSVAMEGV 


    See TATDN3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (5 alternative transcripts): 
    NP_001036017.1  NP_001036018.1  NP_001139641.1  NP_001139642.1  NP_001139643.1  

    ENSEMBL proteins: 
     ENSP00000431376   ENSP00000355941   ENSP00000432730   ENSP00000434801   ENSP00000433755  
     ENSP00000355940   ENSP00000436364   ENSP00000434428   ENSP00000431379   ENSP00000433143  
     ENSP00000434276   ENSP00000475492   ENSP00000432006  

    TATDN3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for TATDN3
    OriGene Protein Over-expression Lysate for TATDN3
    OriGene MassSpec for TATDN3
    OriGene Custom Protein Services for TATDN3
    GenScript Custom Purified and Recombinant Proteins Services for TATDN3
    Novus Biologicals TATDN3 Protein
    Novus Biologicals TATDN3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for TATDN3
    Cloud-Clone Corp. Proteins for TATDN3

    TATDN3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TATDN3
    Novus Biologicals TATDN3 Antibodies
    Abcam antibodies for TATDN3
    Cloud-Clone Corp. Antibodies for TATDN3
    ThermoFisher Antibodies for TATDN3
    LSBio Antibodies in human, mouse, rat for TATDN3

    TATDN3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TATDN3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TATDN3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TATDN3
    Cloud-Clone Corp. CLIAs for TATDN3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR001130 TatD_family

    Graphical View of Domain Structure for InterPro Entry Q17R31

    ProtoNet protein and cluster: Q17R31

    1 Blocks protein domain: IPB001130 TatD-related deoxyribonuclease

    UniProtKB/Swiss-Prot: TATD3_HUMAN, Q17R31
    Similarity: Belongs to the TatD DNase family


    TATDN3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TATD3_HUMAN, Q17R31
    Function: Putative deoxyribonuclease

         Enzyme Numbers (IUBMB): EC 3.1.212 EC 3.1.21.-1

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016888endodeoxyribonuclease activity, producing 5'-phosphomonoesters IEA--
    GO:0046872metal ion binding IEA--
         
    TATDN3 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Tatdn3 (no phenotypes)

    TATDN3 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TATDN3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TATDN3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TATDN3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TATDN3

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat TATDN3 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate TATDN3:
    hsa-miR-182* hsa-miR-4311 hsa-miR-589* hsa-miR-876-3p hsa-miR-105
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TATDN3
    Predesigned siRNA for gene silencing in human, mouse, rat TATDN3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TATDN3

    Clone
    Products:
         
    OriGene clones in human, mouse for TATDN3 (see all 30)
    OriGene ORF clones in mouse, rat for TATDN3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): TATDN3 (NM_001042553)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TATDN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TATDN3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TATDN3
    Browse ESI BIO Cell Lines and PureStem Progenitors for TATDN3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TATDN3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TATD3_HUMAN, Q17R31: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytoskeleton2
    cytosol1
    golgi apparatus1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IBA--
    GO:0005739mitochondrion IEA--

    TATDN3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TATDN3
    Interactions:

        Search GeneGlobe Interaction Network for TATDN3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TATDN3 (ENSP000003559414) via UniProtKB, MINT, STRING, and/or I2D (see all 29)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ADAMTSL4-AS1ENSP000003580314STRING: ENSP00000358031
    APBB1IPENSP000003654114STRING: ENSP00000365411
    APOBEC4ENSP000003106224STRING: ENSP00000310622
    ATPIF1ENSP000003352034STRING: ENSP00000335203
    C1orf105ENSP000003567004STRING: ENSP00000356700
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TATDN3 (TATD3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TATDN3 gene (5 alternative transcripts): 
    NM_001042552.2  NM_001042553.2  NM_001146169.1  NM_001146170.1  NM_001146171.1  

    Unigene Cluster for TATDN3:

    TatD DNase domain containing 3
    Hs.530538  [show with all ESTs]
    Unigene Representative Sequence: NM_001146171
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000532324 ENST00000366974(uc001hjo.2 uc010ptj.1 uc010ptk.1 uc001hjp.2 uc010ptl.1 uc010ptm.1)
    ENST00000530441 ENST00000526641 ENST00000531963 ENST00000366973 ENST00000526997
    ENST00000533650 ENST00000532433 ENST00000488246 ENST00000525574 ENST00000497768
    ENST00000530399 ENST00000525569 ENST00000530392 ENST00000606486 ENST00000527693

    Congresses - knowledge worth sharing:
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TATDN3 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate TATDN3:
    hsa-miR-182* hsa-miR-4311 hsa-miR-589* hsa-miR-876-3p hsa-miR-105
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TATDN3
    Predesigned siRNA for gene silencing in human, mouse, rat TATDN3
    Clone
    Products:
         
    OriGene clones in human, mouse for TATDN3 (see all 30)
    OriGene ORF clones in mouse, rat for TATDN3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): TATDN3 (NM_001042553)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TATDN3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TATDN3
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TATDN3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TATDN3
      QuantiTect SYBR Green Assays in human, mouse, rat TATDN3
      QuantiFast Probe-based Assays in human, mouse, rat TATDN3

    Additional mRNA sequence: 

    AK293129.1 AK295335.1 AK304557.1 AL832248.1 BC048115.1 BC113638.1 BC117485.1 BC143956.1 
    BC143957.1 

    7 DOTS entries:

    DT.452530  DT.100739606  DT.75133493  DT.95362685  DT.100742801  DT.99984295  DT.302776 

    Selected AceView cDNA sequences (see all 75):

    CR619489 BM989374 AI655590 AW611562 AL526258 AV710525 BE501397 BM271845 
    CA433356 BU663725 AA334054 AI990055 BM907308 BI463574 BE044013 BC048115 
    BI545444 BX387124 BM264483 BF796613 AA906896 AL832248 AL562488 AI274071 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TATDN3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GAAGGAGTAA
    TATDN3 Expression
    About this image

    TATDN3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TATDN3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.530538
        Custom PCR Arrays for TATDN3
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TATDN3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TATDN3
    QuantiTect SYBR Green Assays in human, mouse, rat TATDN3
    QuantiFast Probe-based Assays in human, mouse, rat TATDN3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TATDN3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TATDN3 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tatdn31 , 5 TatD DNase domain containing 31, 5 85.19(n)1
    85.93(a)1
      1 (96.28 cM)5
    689721  NM_026895.11  NP_081171.11 
     1910458265 
    chicken
    (Gallus gallus)
    Aves TATDN31 TatD DNase domain containing 3 73.73(n)
    75.46(a)
      421366  XM_419426.4  XP_419426.4 
    lizard
    (Anolis carolinensis)
    Reptilia TATDN36
    TatD DNase domain containing 3
    76(a)
    1 ↔ 1
    1(238696477-238709729)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tatdn31 TatD DNase domain containing 3 70.16(n)
    75.28(a)
      100380120  XM_002934700.2  XP_002934746.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5719121 TatD DNase domain containing 3-like 67.05(n)
    69.32(a)
      571912  NM_001200022.1  NP_001186951.1 
    worm
    (Caenorhabditis elegans)
    Secernentea B0432.81 B0432.8 48.69(n)
    40.55(a)
      181990  NM_061290.3  NP_493691.2 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G035001 AT3G03500 45.34(n)
    31.58(a)
      821247  NM_111221.1  NP_187000.1 


    ENSEMBL Gene Tree for TATDN3 (if available)
    TreeFam Gene Tree for TATDN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TATDN3 (see all 523)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs779251861,2
    C,F--212967202(+) AAGGAA/CTAGGT 5 -- int12Minor allele frequency- C:0.09CSA WA 120
    rs111200281,2
    C,A,H--212967421(+) atcgaC/Gaccat 5 -- int10--------
    rs124097871,2
    C,F,A,H--212967492(+) gcagcG/Atgtgc 5 -- int14Minor allele frequency- A:0.50NA WA CSA 8
    rs75335141,2
    C,A,H--212967576(+) cgagaG/Tcgtga 5 -- int18Minor allele frequency- T:0.00NA WA CSA 17
    rs1897635491,2
    C--212967609(+) CAGAGC/TGAGAC 5 -- int10--------
    rs1138229901,2
    C,F--212967610(+) AGAGCG/AAGACT 5 -- int11Minor allele frequency- A:0.50NA 2
    rs1423404141,2
    --212967660(+) GGGTTC/TGATGG 5 -- int10--------
    rs1169471491,2
    F--212967661(+) GGTTCG/AATGGC 5 -- int11Minor allele frequency- A:0.03EA 120
    rs75195821,2
    C--212967766(+) catctC/Ttacta 5 -- int13Minor allele frequency- T:0.17NA WA 6
    rs18137051,2
    C,A--212967871(-) attgcA/Cacctc 5 -- int18Minor allele frequency- C:0.34NA WA CSA EA 134

    HapMap Linkage Disequilibrium report for TATDN3 (212965170 - 212990167 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TATDN3:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv179e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TATDN3
    DNA2.0 Custom Variant and Variant Library Synthesis for TATDN3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    4 diseases for TATDN3:    
    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    pneumonia    tuberculosis


    TATDN3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TATDN3
    Human Genome Epidemiology (HuGE) Navigator: TATDN3 (1 document)

    Export disorders for TATDN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TATDN3 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TATDN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    2. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    3. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (Biochem. Biophys. Res. Commun. 2006)
    4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    5. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (Nature 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. NotI flanking sequences: a tool for gene discovery and verification of the human genome. (PubMed id 12136098)1 Kutsenko A.S....Zabarovsky E.R. (Nucleic Acids Res. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 128387 HGNC: 27010 AceView: LOC128387 Ensembl:ENSG00000203705 euGenes: HUgn128387
    ECgene: TATDN3 H-InvDB: TATDN3

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TATDN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TATDN3 gene:
    Search GeneIP for patents involving TATDN3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TATDN3  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for TATDN3  
     OriGene MassSpec something-or-other for TATDN3   OriGene clones in human, mouse for TATDN3  
     OriGene qSTAR qPCR primer pairs in human, mouse for TATDN3   OriGene Purified Protein for TATDN3  
     OriGene ORF clones in mouse, rat for TATDN3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TATDN3   OriGene Custom Protein Services for TATDN3  

     
     
     Block miRNA regulation of human, mouse, rat TATDN3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TATDN3
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TATDN3 Predesigned siRNA for gene silencing in human, mouse, rat TATDN3
     QuantiFast Probe-based Assays in human, mouse, rat TATDN3 QuantiTect SYBR Green Assays in human, mouse, rat TATDN3
     Custom PCR Arrays for TATDN3 Search Chromatin IP Primers for TATDN3
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TATDN3  Search GeneGlobe Interaction Network for TATDN3
     Regulatory tfbs in TATDN3 promoter
     GenScript Custom Purified and Recombinant Proteins Services for TATDN3 GenScript cDNA clones with any tag delivered in your preferred vector for TATDN3
     GenScript Custom Assay Services for TATDN3 GenScript Custom overexpressing Cell Line Services for TATDN3
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TATDN3 (TATD3)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TATDN3 antibodies
     TATDN3 proteins
     TATDN3 lysates
     Antibodies for TATDN3
     See all of Abcam's Antibodies, Kits and Proteins for TATDN3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for TATDN3
     Proteins for TATDN3
     Antibodies for TATDN3
     ELISAs for TATDN3
     CLIAs for TATDN3



     Browse ESI BIO Cell Lines and PureStem Progenitors for TATDN3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TATDN3
     Browse SwitchGear 3'UTR luciferase reporter plasmids for TATDN3
     Browse SwitchGear Promoter luciferase reporter plasmids for TATDN3
     ThermoFisher Antibodies for TATDN3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TATDN3
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TATDN3
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TATDN3
     LSBio Antibodies in human, mouse, rat for TATDN3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TATDN3 gene at Home site.
    Version: 3.12.142 28 July 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4