Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TATDN1 Gene

protein-coding   GIFtS: 47
GCID: GC08M125500

TatD DNase Domain Containing 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
TatD DNase Domain Containing 11 2
Hepatocarcinoma High Expression Protein2 3
Putative Deoxyribonuclease TATDN12
EC 3.1.21.-3
EC 3.1.218

External Ids:    HGNC: 242201   Entrez Gene: 839402   Ensembl: ENSG000001476877   UniProtKB: Q6P1N93   

Export aliases for TATDN1 gene to outside databases

Previous GC identifers: GC08M125458 GC08M125569 GC08M120826


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TATDN1 Gene:
TATDN1 (TatD DNase domain containing 1) is a protein-coding gene. Diseases associated with TATDN1 include sporadic pheochromocytoma, and pheochromocytoma. GO annotations related to this gene include endodeoxyribonuclease activity, producing 5'-phosphomonoesters and deoxyribonuclease activity. An important paralog of this gene is TATDN2.

UniProtKB/Swiss-Prot: TATD1_HUMAN, Q6P1N9
Function: Putative deoxyribonuclease (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000008.11  NT_008046.17  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TATDN1 gene promoter:
         TBP   IRF-2   POU2F1   POU2F1a   Lmo2   Nkx2-5   NF-kappaB1   NF-kappaB   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTATDN1 promoter sequence
   Search Chromatin IP Primers for TATDN1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TATDN1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.13   Ensembl cytogenetic band:  8q24.13   HGNC cytogenetic band: 8q24.13

TATDN1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TATDN1 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08M125500:  view genomic region     (about GC identifiers)

Start:
125,500,726 bp from pter      End:
125,551,699 bp from pter
Size:
50,974 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TATD1_HUMAN, Q6P1N9 (See protein sequence)
Recommended Name: Putative deoxyribonuclease TATDN1  
Size: 297 amino acids; 33602 Da
Cofactor: Binds 2 divalent metal cations per subunit (By similarity)
1 PDB 3D structure from and Proteopedia for TATDN1:
2XIO (3D)    
Secondary accessions: B2R5J0 Q8TD02 Q9BY40
Alternative splicing: 2 isoforms:  Q6P1N9-1   Q6P1N9-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TATDN1: NX_Q6P1N9

Explore proteomics data for TATDN1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for TATDN1 (Q6P1N9) (see all 8)
     ETDAPWC  NLTDPMF  VLKSIPSE  FPTKKKWE 


    See TATDN1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001139632.1  NP_114415.1  

    ENSEMBL proteins: 
     ENSP00000431052   ENSP00000276692   ENSP00000428609   ENSP00000428336   ENSP00000430274  
     ENSP00000430201   ENSP00000429831   ENSP00000476180   ENSP00000429541   ENSP00000428580  
     ENSP00000430481   ENSP00000430756   ENSP00000428109   ENSP00000427807  

    TATDN1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for TATDN1
    OriGene Protein Over-expression Lysate for TATDN1
    OriGene MassSpec for TATDN1
    OriGene Custom Protein Services for TATDN1
    GenScript Custom Purified and Recombinant Proteins Services for TATDN1
    Novus Biologicals TATDN1 Protein
    Novus Biologicals TATDN1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TATDN1

    TATDN1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for TATDN1
    OriGene Custom Antibody Services for TATDN1
    Novus Biologicals TATDN1 Antibodies
    Abcam antibodies for TATDN1
    Cloud-Clone Corp. Antibodies for TATDN1
    ThermoFisher Antibodies for TATDN1
    LSBio Antibodies in human, mouse, rat for TATDN1

    TATDN1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TATDN1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TATDN1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TATDN1
    Cloud-Clone Corp. CLIAs for TATDN1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR018228 DNase_TatD-rel_CS
     IPR001130 TatD_family

    Graphical View of Domain Structure for InterPro Entry Q6P1N9

    ProtoNet protein and cluster: Q6P1N9

    1 Blocks protein domain: IPB001130 TatD-related deoxyribonuclease

    UniProtKB/Swiss-Prot: TATD1_HUMAN, Q6P1N9
    Similarity: Belongs to the TatD DNase family


    TATDN1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TATD1_HUMAN, Q6P1N9
    Function: Putative deoxyribonuclease (By similarity)

         Enzyme Numbers (IUBMB): EC 3.1.212 EC 3.1.21.-1

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004536deoxyribonuclease activity IBA--
    GO:0016888endodeoxyribonuclease activity, producing 5'-phosphomonoesters IEA--
    GO:0046872metal ion binding IEA--
         
    TATDN1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TATDN1:
     Decreased number of cells in m 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TATDN1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TATDN1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TATDN1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TATDN1

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat TATDN1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TATDN1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TATDN1
    Predesigned siRNA for gene silencing in human, mouse, rat TATDN1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TATDN1

    Clone
    Products:
         
    OriGene clones in human, mouse for TATDN1 (see all 14)
    OriGene ORF clones in mouse, rat for TATDN1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TATDN1 (NM_032026)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TATDN1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TATDN1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TATDN1
    Browse ESI BIO Cell Lines and PureStem Progenitors for TATDN1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TATDN1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TATD1_HUMAN, Q6P1N9: Nucleus (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    extracellular1
    mitochondrion1
    plasma membrane1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IBA--
    GO:0005737cytoplasm IBA--

    TATDN1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TATDN1
    Interactions:

        Search GeneGlobe Interaction Network for TATDN1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for TATDN1 (Q6P1N93 ENSP000002766924) via UniProtKB, MINT, STRING, and/or I2D (see all 37)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EXOSC9Q062653, ENSP000003689844I2D: score=3 STRING: ENSP00000368984
    AURKCQ9UQB93I2D: score=2 
    CAMK1DQ8IU853I2D: score=2 
    CSNK1G2P783683I2D: score=2 
    MAPK1P284823I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006309apoptotic DNA fragmentation IBA--

    TATDN1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TATDN1 (TATD1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TATDN1 gene (2 alternative transcripts): 
    NM_001146160.1  NM_032026.3  

    Unigene Cluster for TATDN1:

    TatD DNase domain containing 1
    Hs.170568  [show with all ESTs]
    Unigene Representative Sequence: AK127148
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000522927 ENST00000276692 ENST00000523214(uc003yre.2 uc003yrd.2 uc010mdm.2)
    ENST00000523631 ENST00000519548 ENST00000522810 ENST00000518485 ENST00000517678
    ENST00000519776 ENST00000521546 ENST00000521973 ENST00000605953 ENST00000520321
    ENST00000522310 ENST00000519232 ENST00000520938 ENST00000523888 ENST00000523152

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TATDN1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TATDN1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TATDN1
    Predesigned siRNA for gene silencing in human, mouse, rat TATDN1
    Clone
    Products:
         
    OriGene clones in human, mouse for TATDN1 (see all 14)
    OriGene ORF clones in mouse, rat for TATDN1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TATDN1 (NM_032026)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TATDN1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TATDN1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TATDN1
    OriGene qSTAR qPCR primer pairs in human, mouse for TATDN1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TATDN1
      QuantiTect SYBR Green Assays in human, mouse, rat TATDN1
      QuantiFast Probe-based Assays in human, mouse, rat TATDN1

    Additional mRNA sequence: 

    AF212250.1 AK094861.1 AK125270.1 AK127148.1 AK312204.1 AY071865.1 BC007066.1 BC064964.1 
    NR_027427.1 

    Selected DOTS entries (see all 27):

    DT.452925  DT.100832280  DT.92449754  DT.92429295  DT.92449737  DT.121260186  DT.100793718  DT.453008 
    DT.95305369  DT.121486196  DT.100793724  DT.92449741  DT.91803611  DT.99973193  DT.102837978  DT.121259997 
    DT.121486172  DT.121486314  DT.121486479  DT.92029098  DT.92040118  DT.92449736  DT.92449743  DT.100695794 

    Selected AceView cDNA sequences (see all 218):

    AA378892 BG532054 BQ440040 BU786374 AA736458 BM718113 NM_032026 BI712503 
    AA305302 BM979473 CB144514 BU784642 BP429407 BU687281 BU150780 BG547415 
    BX332564 AI128731 BC064964 AV733010 AA308284 CR614010 BE884168 AF212250 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TATDN1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATGTAAAAT
    TATDN1 Expression
    About this image

    TATDN1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TATDN1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.170568
        Custom PCR Arrays for TATDN1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TATDN1
    OriGene qSTAR qPCR primer pairs in human, mouse for TATDN1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TATDN1
    QuantiTect SYBR Green Assays in human, mouse, rat TATDN1
    QuantiFast Probe-based Assays in human, mouse, rat TATDN1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TATDN1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TATDN1 gene from Selected species (see all 25)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tatdn11 , 5 TatD DNase domain containing 11, 5 89.02(n)1
    90.53(a)1
      15 (25.09 cM)5
    696941  NM_175151.41  NP_780360.11 
     588901535 
    chicken
    (Gallus gallus)
    Aves TATDN11 TatD DNase domain containing 1 78.56(n)
    83.5(a)
      770677  XM_001234015.3  XP_001234016.1 
    lizard
    (Anolis carolinensis)
    Reptilia TATDN16
    TatD DNase domain containing 1
    82(a)
    1 ↔ 1
    4(6265679-6275258)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.136462 Xenopus laevis transcribed sequence with weak similarity more 74.13(n)    CD327085.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tatdn11 TatD DNase domain containing 1 65.99(n)
    70.75(a)
      100151626  NM_001002213.1  NP_001002213.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG33581 CG3358 53.07(n)
    48.74(a)
      35604  NM_001259227.2  NP_001246156.2 
    worm
    (Caenorhabditis elegans)
    Secernentea crn-26
    Protein CRN-2 (crn-2) mRNA, complete cds
    29(a)
    many ↔ many
    V(5594615-5595748) WBGene00000795
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes (YBL055C)4
    YBL055C1
    3'-->5' exonuclease and endonuclease with a possible more4
    YBL055C1
    53.2(n)1
    43.49(a)1
      2(116829-115573)4
    8522251, 4  NP_009498.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT3G523901 AT3G52390 55.14(n)
    51.53(a)
      824404  NM_115099.4  NP_190807.3 
    rice
    (Oryza sativa)
    Liliopsida Os07g01582001 Os07g0158200 56.7(n)
    53.26(a)
      4342437  NM_001065461.1  NP_001058926.1 


    ENSEMBL Gene Tree for TATDN1 (if available)
    TreeFam Gene Tree for TATDN1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TATDN1 gene
    TATDN22  ENSG000002724102  

    TATDN1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TATDN1
    PGOHUM00000238810


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TATDN1 (see all 966)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1899936631,2
    --125501444(+) TTGAGA/GGACAG 3 -- int10--------
    rs1415227951,2
    --125501471(+) GTTGCC/TGCAAA 3 -- int10--------
    rs1825749471,2
    C--125501486(+) ATATTA/TACTTG 3 -- int10--------
    rs794849321,2
    C,F--125501542(+) CCTTGC/TGAGAG 3 -- int11Minor allele frequency- T:0.22WA 118
    rs114431801,2
    C--125501644(+) TTTTTT/-CTTTT 3 -- int1 trp32Minor allele frequency- -:0.25NA CSA 4
    rs1504120091,2
    --125501723(+) GATCTC/TGGCTC 3 -- int10--------
    rs1135339531,2
    F--125501801(+) AGGCAT/CCTGCC 3 -- int11Minor allele frequency- C:0.00CSA 1
    rs1180957211,2
    C,F--125501868(+) TGGCCG/ATGGTC 3 -- int11Minor allele frequency- A:0.05EA 120
    rs69939261,2
    C,F,A--125501889(+) GACCTT/CGTGAT 3 -- int18Minor allele frequency- C:0.45NA WA CSA EA 249
    rs1158755281,2
    F--125501992(+) TGATCC/TGTAGT 3 -- int11Minor allele frequency- T:0.04WA 118

    HapMap Linkage Disequilibrium report for TATDN1 (125500726 - 125551699 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TATDN1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv274383CNV Insertion20981092

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TATDN1
    DNA2.0 Custom Variant and Variant Library Synthesis for TATDN1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    4 diseases for TATDN1:    
    About MalaCards
    sporadic pheochromocytoma    pheochromocytoma    pneumonia    malaria


    TATDN1 for disorders           About GeneDecksing


    Export disorders for TATDN1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TATDN1 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with TATDN1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    3. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    5. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    8. Genome-scale RNAi screen for host factors required for HIV replication. (PubMed id 18976975)1 Zhou H....Espeseth A.S. (amp 2008)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. The gene expression profiling of sporadic pheochromocytoma and novel full-length cDNAs cloning. (PubMed id 14713272)1 Yang Y.-S.... Chen J.-L. (Endocr. Relat. Cancer 2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 83940 HGNC: 24220 AceView: TATDN1 Ensembl:ENSG00000147687 euGenes: HUgn83940
    ECgene: TATDN1 H-InvDB: TATDN1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TATDN1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TATDN1 gene:
    Search GeneIP for patents involving TATDN1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for TATDN1   OriGene RNAi products in human, mouse, rat for TATDN1  
     OriGene qPCR primer pairs and template standards for TATDN1   OriGene Protein Over-expression Lysate for TATDN1  
     OriGene MassSpec something-or-other for TATDN1   OriGene clones in human, mouse for TATDN1  
     OriGene qSTAR qPCR primer pairs in human, mouse for TATDN1   OriGene Purified Protein for TATDN1  
     OriGene ORF clones in mouse, rat for TATDN1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TATDN1   OriGene Custom Protein Services for TATDN1  

     
     
     Block miRNA regulation of human, mouse, rat TATDN1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TATDN1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TATDN1 Predesigned siRNA for gene silencing in human, mouse, rat TATDN1
     QuantiFast Probe-based Assays in human, mouse, rat TATDN1 QuantiTect SYBR Green Assays in human, mouse, rat TATDN1
     Custom PCR Arrays for TATDN1 Search Chromatin IP Primers for TATDN1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TATDN1  Search GeneGlobe Interaction Network for TATDN1
     Regulatory tfbs in TATDN1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for TATDN1 GenScript cDNA clones with any tag delivered in your preferred vector for TATDN1
     GenScript Custom Assay Services for TATDN1 GenScript Custom overexpressing Cell Line Services for TATDN1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TATDN1 (TATD1)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TATDN1 antibodies
     TATDN1 proteins
     TATDN1 lysates
     Antibodies for TATDN1
     See all of Abcam's Antibodies, Kits and Proteins for TATDN1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TATDN1
     Antibodies for TATDN1
     ELISAs for TATDN1
     CLIAs for TATDN1



     Browse ESI BIO Cell Lines and PureStem Progenitors for TATDN1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TATDN1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for TATDN1
     SwitchGear Promoter luciferase reporter plasmids for TATDN1
     ThermoFisher Antibodies for TATDN1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TATDN1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TATDN1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TATDN1
     LSBio Antibodies in human, mouse, rat for TATDN1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TATDN1 gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4