Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TAS2R45 Gene

protein-coding   GIFtS: 40
GCID: GC12M9R0327

Taste Receptor, Type 2, Member 45

(Previous name: G protein-coupled receptor 59)
(Previous symbol: GPR59)
  Search for TAS2R45
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Taste Receptor, Type 2, Member 451 2     G-Protein Coupled Receptor 592 3
GPR591 2 3     ZG24P2
T2R452 3 5     Taste Receptor Type 2 Member 452
G Protein-Coupled Receptor 591 2     

External Ids:    HGNC: 188761   Entrez Gene: 2592912   OMIM: 6139675   UniProtKB: P595393   

Export aliases for TAS2R45 gene to outside databases

Previous GC identifers: GC00U991254 GC12M011106 GC00P9A0411 GC12P9J0411 GC12U900566 GC12M011213 GC12M011012


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for TAS2R45 Gene:
TAS2R45 (taste receptor, type 2, member 45) is a protein-coding gene. GO annotations related to this gene include G-protein coupled receptor activity.

UniProtKB/Swiss-Prot: T2R45_HUMAN, P59539
Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role
in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate
alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity)

Gene Wiki entry for TAS2R45 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Search for regulatory transcription factor binding sites for TAS2R45
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TAS2R45

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TAS2R45


Genomic Location:
Chromosome:12   

HGNC chromosome: 12

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M9R0327:       (about GC identifiers)

Start:
327,525 bp from start of contig NW_003571050      End:
328,424 bp from start of contig NW_003571050
Size:
900 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: T2R45_HUMAN, P59539 (See protein sequence)
Recommended Name: Taste receptor type 2 member 45  
Size: 299 amino acids; 34278 Da
Miscellaneous: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells
can discriminate among bitter stimuli

Explore the universe of human proteins at neXtProt for TAS2R45: NX_P59539

Post-translational modifications: 

  • Glycosylation2 at Asn161
  • REFSEQ proteins: NP_795367.2  Reactome Protein details: P59539

    TAS2R45 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TAS2R45
    GenScript Custom Purified and Recombinant Proteins Services for TAS2R45
    Novus Biologicals TAS2R45 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TAS2R45

     
    Search eBioscience for Proteins for TAS2R45 

    TAS2R45 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TAS2R45
    Novus Biologicals TAS2R45 Antibody
    Abcam antibodies for TAS2R45
    Cloud-Clone Corp. Antibodies for TAS2R45
    ThermoFisher Antibodies for TAS2R45
    LSBio Antibodies in human, mouse, rat for TAS2R45

    TAS2R45 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TAS2R45
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TAS2R45
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TAS2R45
    Cloud-Clone Corp. CLIAs for TAS2R45
    Search eBioscience for ELISAs for TAS2R45 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    TASNR: GPCR / Unclassified : Taste receptors
    TAS2R: Taste receptors / Type 2

    1 InterPro protein domain:
     IPR007960 TAS2_rcpt

    Graphical View of Domain Structure for InterPro Entry P59539

    ProtoNet protein and cluster: P59539

    UniProtKB/Swiss-Prot: T2R45_HUMAN, P59539
    Similarity: Belongs to the G-protein coupled receptor T2R family


    Find genes that share domains with TAS2R45           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: T2R45_HUMAN, P59539
    Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role
    in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate
    alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
         
    Find genes that share ontologies with TAS2R45           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for TAS2R45:
     Decreased POU5F1-GFP protein e  Decreased viability with pacli 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TAS2R45
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TAS2R45

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TAS2R45
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TAS2R45

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat TAS2R45 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TAS2R45
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TAS2R45
    Predesigned siRNA for gene silencing in human, mouse, rat TAS2R45

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TAS2R45

    Clone
    Products:
         
    OriGene clones in human, mouse for TAS2R45 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TAS2R45 (NM_176886)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TAS2R45
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAS2R45

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TAS2R45
    Browse ESI BIO Cell Lines and PureStem Progenitors for TAS2R45 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAS2R45


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    T2R45_HUMAN, P59539: Membrane; Multi-pass membrane protein

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with TAS2R45           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for TAS2R45 About    
    See pathways by source

    SuperPathContained pathways About
    1Taste transduction
    Class C/3 (Metabotropic glutamate/pheromone receptors)0.45
    Taste transduction0.45
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.58
    GPCR downstream signaling0.90
    3Peptide ligand-binding receptors
    GPCR ligand binding0.71
    G alpha (i) signalling events0.44


    Find genes that share SuperPaths with TAS2R45           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Reactome Pathways for TAS2R45
        Class C/3 (Metabotropic glutamate/pheromone receptors)
    G alpha (i) signalling events


    1 Kegg Pathway  (Kegg details for TAS2R45):
        Taste transduction

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TAS2R45
    Interactions:

        Search GeneGlobe Interaction Network for TAS2R45

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0050909sensory perception of taste IEA--

    Find genes that share ontologies with TAS2R45           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TAS2R45 (T2R45)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TAS2R45 gene: 
    NM_176886.2  

    Unigene Cluster for TAS2R45:

    Taste receptor, type 2, member 45
    Hs.287378  [show with all ESTs]
    Unigene Representative Sequence: NM_176886
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TAS2R45 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TAS2R45
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TAS2R45
    Predesigned siRNA for gene silencing in human, mouse, rat TAS2R45
    Clone
    Products:
         
    OriGene clones in human, mouse for TAS2R45 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TAS2R45 (NM_176886)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TAS2R45
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAS2R45
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TAS2R45
    OriGene qSTAR qPCR primer pairs in human, mouse for TAS2R45
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat TAS2R45
      QuantiTect SYBR Green Assays in human, mouse, rat TAS2R45
      QuantiFast Probe-based Assays in human, mouse, rat TAS2R45

    Additional mRNA sequence: 

    AF264628.1 BC101154.1 BC101156.1 

    2 DOTS entries:

    DT.121204118  DT.86859104 

    3 AceView cDNA sequences:

    NM_176886 AW266498 AF264628 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TAS2R45 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCTGCCAAG
    TAS2R45 Expression
    About this image

    TAS2R45 Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene cluster: Hs.287378

    UniProtKB/Swiss-Prot: T2R45_HUMAN, P59539
    Tissue specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in
    gustducin-positive cells

        Custom PCR Arrays for TAS2R45
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for TAS2R45
    OriGene qSTAR qPCR primer pairs in human, mouse for TAS2R45
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat TAS2R45
    QuantiTect SYBR Green Assays in human, mouse, rat TAS2R45
    QuantiFast Probe-based Assays in human, mouse, rat TAS2R45
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAS2R45

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus
      --

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TAS2R45 gene
    Selected SIMAP similar genes for TAS2R45 using alignment to 2 protein entries:     T2R45_HUMAN (see all proteins) (see all similar genes):
    Hosa(Japanese)-T2R45    TAS2R46    Hosa(Adygei)-T2R46    Hosa(Biaka)-T2R46    Hosa(Biaka)-T2R43    TAS2R43
    TAS2R31    Hosa(Biaka)-T2R47    TAS2R30    Hosa(Biaka)-T2R48    Hosa(Japanese)-T2R48    Hosa(Adygei)-T2R50
    TAS2R50    Hosa(Biaka)-T2R50    Hosa(Japanese)-T2R50    TAS2R19    Hosa(Adygei)-T2R49    Hosa(Biaka)-T2R49

    Find genes that share paralogs with TAS2R45           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TAS2R45 (see all 90)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs740624341,2
    C,F--11118538(+) TTTCCG/AGGGAT 1 -- ds50013Minor allele frequency- A:0.13WA CSA 121
    rs780724571,2
    C--11118553(+) TCTTAC/GTTCTT 1 -- ds50010--------
    rs730649591,2
    C--11118580(+) CATTGC/TAAATT 1 -- ds50010--------
    rs1897133981,2
    --11118613(+) ATGAAC/TGAAAT 1 -- ds50010--------
    rs3758436191,2
    C--11118620(+) AAATAA/TCATGG 1 -- ds50010--------
    rs1394219621,2
    --11118736(+) ACACAA/CATACA 1 -- ds50010--------
    rs1869947631,2
    --11118762(+) ATTTTC/TTAGAC 1 -- ds50010--------
    rs789659281,2
    C,F--11118793(+) GTATAC/TGTTTG 1 -- ds50012Minor allele frequency- T:0.47WA NA 238
    rs1834018791,2
    --11118814(+) ATACAC/GATACA 1 -- ds50010--------
    rs1451799171,2
    --11118820(+) ATACAG/TTATAG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for TAS2R45 (327525 - 328424 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TAS2R45: --
    Human Gene Mutation Database (HGMD): TAS2R45
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing TAS2R45
    DNA2.0 Custom Variant and Variant Library Synthesis for TAS2R45

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 613967    OMIM disorders: --


    Find genes that share disorders with TAS2R45           About GenesLikeMe


    Export disorders for TAS2R45 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TAS2R45 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TAS2R45)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human TAS2R16 receptor mediates bitter taste in response to beta- glucopyranosides. (PubMed id 12379855)1, 2, 3 Bufe B.... Meyerhof W. (Nat. Genet. 2002)
    2. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. (PubMed id 12581520)1, 2 Zhang Y.... Ryba N.J. (Cell 2003)
    3. Molecular mechanisms of bitter and sweet taste transduction. (PubMed id 11696554)1, 2 Margolskee R.F. (J. Biol. Chem. 2002)
    4. Receptors for bitter and sweet taste. (PubMed id 12139982)1, 2 Montmayeur J.-P. and Matsunami H. (Curr. Opin. Neurobiol. 2002)
    5. Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates. (PubMed id 15744053)1 Go Y.... Takahata N. (Genetics 2005)
    6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 259291 HGNC: 18876 AceView: TAS2R45 euGenes: HUgn259291 ECgene: TAS2R45 Kegg: 259291
    H-InvDB: TAS2R45

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TAS2R45 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TAS2R45 gene:
    Search GeneIP for patents involving TAS2R45

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TAS2R45  
     OriGene qPCR primer pairs and template standards for TAS2R45   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TAS2R45  
     OriGene qSTAR qPCR primer pairs in human, mouse for TAS2R45   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TAS2R45   OriGene Custom Protein Services for TAS2R45  

     
     
     Block miRNA regulation of human, mouse, rat TAS2R45 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TAS2R45
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TAS2R45 Predesigned siRNA for gene silencing in human, mouse, rat TAS2R45
     QuantiFast Probe-based Assays in human, mouse, rat TAS2R45 QuantiTect SYBR Green Assays in human, mouse, rat TAS2R45
     Custom PCR Arrays for TAS2R45 Search Chromatin IP Primers for TAS2R45
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat TAS2R45  Search GeneGlobe Interaction Network for TAS2R45
     Search Regulatory tfbs for TAS2R45
     GenScript Custom Purified and Recombinant Proteins Services for TAS2R45 GenScript cDNA clones with any tag delivered in your preferred vector for TAS2R45
     GenScript Custom Assay Services for TAS2R45 GenScript Custom overexpressing Cell Line Services for TAS2R45
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TAS2R45 (T2R45)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     TAS2R45 antibodies
     TAS2R45 proteins
     Antibodies for TAS2R45
     See all of Abcam's Antibodies, Kits and Proteins for TAS2R45
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for TAS2R45
     Antibodies for TAS2R45
     ELISAs for TAS2R45
     CLIAs for TAS2R45



     Browse ESI BIO Cell Lines and PureStem Progenitors for TAS2R45
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAS2R45
     Browse SwitchGear 3'UTR luciferase reporter plasmids for TAS2R45
     Browse SwitchGear Promoter luciferase reporter plasmids for TAS2R45
     ThermoFisher Antibodies for TAS2R45
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAS2R45
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TAS2R45
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TAS2R45
     LSBio Antibodies in human, mouse, rat for TAS2R45
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for TAS2R45
      Search eBioscience for proteins for TAS2R45
      Search eBioscience for elisas for TAS2R45
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TAS2R45 gene at Home site.
    Version: 3.12.202 14 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4