Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TAS2R31 Gene

protein-coding   GIFtS: 48
GCID: GC12M011183

Taste Receptor, Type 2, Member 31

(Previous names: taste receptor, type 2, member 44)
(Previous symbol: TAS2R44)
  Search for TAS2R31
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Taste Receptor, Type 2, Member 311 2     Taste Receptor Type 2 Member 532 3
TAS2R441 2 3 5     T2R312 3
T2R532 3 5     T2R442 3
Taste Receptor, Type 2, Member 441 2     Taste Receptor Type 2 Member 312
Taste Receptor Type 2 Member 442 3     

External Ids:    HGNC: 191131   Entrez Gene: 2592902   Ensembl: ENSG000002564367   OMIM: 6126695   UniProtKB: P595383   

Export aliases for TAS2R31 gene to outside databases

Previous GC identifers: GC00U991286 GC12U900761 GC12M011078 GC12M010911


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TAS2R31 Gene:
TAS2R44 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells
and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002
(PubMed 12584440)). For further information on TAS2Rs, see MIM 604791.(supplied by OMIM, Mar 2009)

GeneCards Summary for TAS2R31 Gene: 
TAS2R31 (taste receptor, type 2, member 31) is a protein-coding gene. Among its related super-pathways are Taste transduction and Signaling by GPCR. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is TAS2R41.

UniProtKB/Swiss-Prot: T2R31_HUMAN, P59538
Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role
in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate
alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). Activated by the
sulfonyl amide sweeteners saccharin and acesulfame K

Gene Wiki entry for TAS2R31 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.2  NT_009714.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TAS2R31 gene promoter:
         FOXF2   FOXO4   FOXO3a   FOXO3   HNF-3beta   FOXO3b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTAS2R31 promoter sequence
   Search SABiosciences Chromatin IP Primers for TAS2R31

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAS2R31


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.2   Ensembl cytogenetic band:  12p13.2   HGNC cytogenetic band: 12p13.2

TAS2R31 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAS2R31 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M011183:  view genomic region     (about GC identifiers)

Start:
11,182,986 bp from pter      End:
11,184,006 bp from pter
Size:
1,021 bases      Orientation:
minus strand

2 alternative locations:
Chr12-,NW_003571047 229,403-230,423      Chr12-,NW_003571050 229,093-230,113     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: T2R31_HUMAN, P59538 (See protein sequence)
Recommended Name: Taste receptor type 2 member 31  
Size: 309 amino acids; 35278 Da
Subcellular location: Membrane; Multi-pass membrane protein
Miscellaneous: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells
can discriminate among bitter stimuli
Secondary accessions: P59547 Q17R84 Q645X5

Explore the universe of human proteins at neXtProt for TAS2R31: NX_P59538

Explore proteomics data for TAS2R31 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P59538

  • TAS2R31 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TAS2R31 Protein Expression
    REFSEQ proteins: NP_795366.2  
    ENSEMBL proteins: 
     ENSP00000375093  
    Reactome Protein details: P59538
    Human Recombinant Protein Products for TAS2R31: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for TAS2R31
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for TAS2R31
    GenScript Custom Purified and Recombinant Proteins Services for TAS2R31
    Novus Biologicals TAS2R31 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TAS2R31 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane IEA--

    TAS2R31 for ontologies           About GeneDecksing



    TAS2R31 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TAS2R31
    GenScript Custom Superior Antibodies Services for TAS2R31
    Novus Biologicals TAS2R31 Antibody
    Abcam antibodies for TAS2R31
    Cloud-Clone Corp. Antibodies for TAS2R31 
    ThermoFisher Antibodies for TAS2R31
    LSBio Antibodies in human, mouse, rat for TAS2R31 

    Assay Products for TAS2R31: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TAS2R31
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TAS2R31
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TAS2R31 
    Cloud-Clone Corp. CLIAs for TAS2R31


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TASNR: GPCR / Unclassified : Taste receptors
    TAS2R: Taste receptors / Type 2

    IUPHAR Guide to PHARMACOLOGY protein family classification: TAS2R31 
    Taste 2 receptors

    1 InterPro protein domain:
     IPR007960 TAS2_rcpt

    Graphical View of Domain Structure for InterPro Entry P59538

    ProtoNet protein and cluster: P59538

    UniProtKB/Swiss-Prot: T2R31_HUMAN, P59538
    Similarity: Belongs to the G-protein coupled receptor T2R family


    TAS2R31 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: T2R31_HUMAN, P59538
    Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role
    in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate
    alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). Activated by the
    sulfonyl amide sweeteners saccharin and acesulfame K

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
         
    TAS2R31 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TAS2R31 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TAS2R31

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TAS2R31 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TAS2R31 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TAS2R31
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TAS2R31
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TAS2R31
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TAS2R31

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TAS2R31
    Sirion Biotech Customized adenovirus for overexpression of TAS2R31

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TAS2R31 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TAS2R31 (NM_176885)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TAS2R31
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAS2R31
    Sirion Biotech Customized lentivirus for stable overexpression of TAS2R31 
                         Customized lentivirus expression plasmids for stable overexpression of TAS2R31 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TAS2R31
    Search LifeMap BioReagents cell lines for TAS2R31
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAS2R31


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TAS2R31 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Class C/3 (Metabotropic glutamate/pheromone receptors)
    Class C/3 (Metabotropic glutamate/pheromone receptors)0.45
    Taste transduction0.45
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.55
    GPCR downstream signaling0.90
    3Class A/1 (Rhodopsin-like receptors)
    GPCR ligand binding0.71
    G alpha (i) signalling events0.46
    4Sweet Taste Signaling
    Bitter Taste Signaling0.44

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for TAS2R31
        Bitter Taste Signaling

    5/6        Reactome Pathways for TAS2R31 (see all 6)
        GPCR downstream signaling
    Signal Transduction
    Class C/3 (Metabotropic glutamate/pheromone receptors)
    Signaling by GPCR
    G alpha (i) signalling events


    1         Kegg Pathway  (Kegg details for TAS2R31):
        Taste transduction


    TAS2R31 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TAS2R31

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for TAS2R31 (ENSP000003750934) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GNAT3ENSP000003813394STRING: ENSP00000381339
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway ----
    GO:0050909sensory perception of taste IEA--

    TAS2R31 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TAS2R31 (T2R31)

    8 BitterDB Bitter Compounds for TAS2R31 About this table
    CompoundSMILES CAS #
    acesulfame K[K+].CC1=CC(=NS(=O)(=O)O1)[O-]--
    aloinOC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)[C@@H]2c3cccc(O)c3C(=O)c4c(O)cc(CO)cc248015-61-0
    Aristolochic acidCOc1cccc2c1cc(c3c(cc4OCOc4c23)C(=O)O)[N+](=O)[O-]--
    diphenidolOC(CCCN1CCCCC1)(c2ccccc2)c3ccccc3--
    famotidineNC(=Nc1nc(CSCCC(=NS(=O)(=O)N)N)cs1)N--
    ParthenolideCC1=C/CC[C@@]2(C)O[C@H]2[C@H]3OC(=O)C(=C)[C@@H]3CC1--
    Quinine COc1ccc2nccc([C@@H](O)[C@@H]3CC4CCN3C[C@@H]4C=C)c2c1--
    saccharinO=C1NS(=O)(=O)c2ccccc1281-07-2


    Search CenterWatch for drugs/clinical trials and news about TAS2R31 / T2R31

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TAS2R31 gene: 
    NM_176885.2  

    Unigene Cluster for TAS2R31:

    Taste receptor, type 2, member 31
    Hs.688197
    Unigene Representative Sequence: BC117421
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000390675(uc001qzo.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TAS2R31
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TAS2R31
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TAS2R31
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TAS2R31
    Clone
    Products:
         
    OriGene clones in human, mouse for TAS2R31 (see all 5)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TAS2R31 (NM_176885)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TAS2R31
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAS2R31
    Sirion Biotech Customized lentivirus for stable overexpression of TAS2R31 
                         Customized lentivirus expression plasmids for stable overexpression of TAS2R31 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TAS2R31
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TAS2R31
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAS2R31
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAS2R31

    Additional mRNA sequence: BC117421.1 

    1 DOTS entry:

    DT.100736827 

    1 AceView cDNA sequence:

    NM_176885 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TAS2R31 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAGGGGCAT
    TAS2R31 Expression
    About this image


    See TAS2R31 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.688197

    UniProtKB/Swiss-Prot: T2R31_HUMAN, P59538
    Tissue specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in
    gustducin-positive cells

        SABiosciences Custom PCR Arrays for TAS2R31
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TAS2R31
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TAS2R31
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAS2R31
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAS2R31
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAS2R31

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for TAS2R31 (if available)
    TreeFam Gene Tree for TAS2R31 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TAS2R31 gene
    TAS2R412  TAS2R52  TAS2R462  TAS2R162  TAS2R32  TAS2R432  TAS2R142  TAS2R392  
    TAS2R382  TAS2R422  TAS2R92  TAS2R42  TAS2R302  TAS2R12  TAS2R192  TAS2R72  
    TAS2R202  TAS2R82  TAS2R102  TAS2R502  TAS2R132  TAS2R402  TAS2R602  
    18/48 SIMAP similar genes for TAS2R31 using alignment to 1 protein entry:     T2R31_HUMAN(see all similar genes):
    Hosa(Biaka)-T2R43    TAS2R43    Hosa(Adygei)-T2R46    Hosa(Biaka)-T2R46    Hosa(Japanese)-T2R45    TAS2R45
    TAS2R46    Hosa(Biaka)-T2R47    TAS2R30    Hosa(Adygei)-T2R50    Hosa(Biaka)-T2R48    Hosa(Japanese)-T2R48
    Hosa(Biaka)-T2R50    Hosa(Japanese)-T2R50    TAS2R19    TAS2R50    Hosa(Biaka)-T2R49    Hosa(Adygei)-T2R49

    TAS2R31 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    6 SNPs in TAS2R31 are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0306864
    ----see VAR_0306862 Q E mis40--------
    VAR_0306884
    ----see VAR_0306882 V I mis40--------
    VAR_0306854
    ----see VAR_0306852 L M mis40--------
    VAR_0620904
    ----see VAR_0620902 P R mis40--------
    VAR_0306874
    ----see VAR_0306872 A V mis40--------
    VAR_0306844
    ----see VAR_0306842 R W mis40--------

    HapMap Linkage Disequilibrium report for TAS2R31 (11182986 - 11184006 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/18 variations for TAS2R31 (see all 18):    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv265e199CNV Deletion23128226
    esv2664609CNV Deletion23128226
    dgv266e199CNV Deletion23128226
    dgv267e199CNV Deletion23128226
    nsv436149CNV Deletion17901297
    esv2745546CNV Deletion23290073
    dgv191e201CNV Deletion23290073
    esv2670207CNV Deletion23128226
    nsv8917CNV Loss18304495
    esv24685CNV Loss19812545


    Human Gene Mutation Database (HGMD): TAS2R31
    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing TAS2R31
    DNA2.0 Custom Variant and Variant Library Synthesis for TAS2R31

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TAS2R31 for disorders           About MalaCards
    OMIM gene information: 612669    OMIM disorders: --


    TAS2R31 for disorders           About GeneDecksing


    Export disorders for TAS2R31 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TAS2R31 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with TAS2R31)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evolution of bitter taste receptors in humans and apes. (PubMed id 15496549)1, 2 Fischer A.... Paeaebo S. (2005)
    2. Bitter taste receptors for saccharin and acesulfame K. (PubMed id 15537898)1, 2 Kuhn C.... Meyerhof W. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. (PubMed id 12581520)1, 2 Zhang Y.... Ryba N.J. (2003)
    5. Identification and characterization of human taste receptor genes belonging to the TAS2R family. (PubMed id 12584440)1, 2 Conte C.... Andres-Barquin P.J. (2002)
    6. The human TAS2R16 receptor mediates bitter taste in response to beta- glucopyranosides. (PubMed id 12379855)1, 2 Bufe B.... Meyerhof W. (2002)
    7. Molecular mechanisms of bitter and sweet taste transduction. (PubMed id 11696554)1, 2 Margolskee R.F. (2002)
    8. Receptors for bitter and sweet taste. (PubMed id 12139982)1, 2 Montmayeur J.-P. and Matsunami H. (2002)
    9. Genomic, genetic and functional dissection of bitter taste responses to artificial sweeteners. (PubMed id 21672920)1 Roudnitzky N....Wooding S.P. (2011)
    10. Specific alleles of bitter receptor genes influence human sensitivity to the bitterness of aloin and saccharin. (PubMed id 17702579)1 Pronin A.N....Li X. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 259290 HGNC: 19113 AceView: TAS2R44 Ensembl:ENSG00000256436 euGenes: HUgn259290
    ECgene: TAS2R31 Kegg: 259290 H-InvDB: TAS2R31

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TAS2R31 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TAS2R31 gene:
    Search GeneIP for patents involving TAS2R31

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TAS2R31  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for TAS2R31  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TAS2R31  
     OriGene qSTAR qPCR primer pairs in human, mouse for TAS2R31   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TAS2R31   OriGene Custom Protein Services for TAS2R31  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TAS2R31
     QIAGEN SeqTarget long-range PCR primers for resequencing TAS2R31
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAS2R31
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TAS2R31
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAS2R31
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAS2R31
     GenScript Custom Purified and Recombinant Proteins Services for TAS2R31 GenScript cDNA clones with any tag delivered in your preferred vector for TAS2R31
     GenScript Custom Assay Services for TAS2R31 GenScript Custom Superior Antibodies Services for TAS2R31
     GenScript Custom overexpressing Cell Line Services for TAS2R31 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TAS2R31 promoter
     Search Chromatin IP Primers for TAS2R31
     RT2 qPCR Primer Assay in human, mouse, rat TAS2R31
     Search GNC Networks for TAS2R31
     SABiosciences PCR Arrays including human, mouse, rat TAS2R31
     Search Tocris compounds for TAS2R31 (T2R31)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TAS2R31 antibodies
     TAS2R31 proteins
     Antibodies for TAS2R31
     See all of Abcam's Antibodies, Kits and Proteins for TAS2R31
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for TAS2R31
     Antibodies for TAS2R31
     ELISAs for TAS2R31
     CLIAs for TAS2R31
     Search LifeMap BioReagents cell lines for TAS2R31
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAS2R31
     Browse SwitchGear 3'UTR luciferase reporter plasmids for TAS2R31
     SwitchGear Promoter luciferase reporter plasmids for TAS2R31
     ThermoFisher Antibodies for TAS2R31
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAS2R31
     inGenious Targeting Laboratory - Custom generated mouse model solutions for TAS2R31
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TAS2R31
    Customized:
     lentivirus for stable overexpression of TAS2R31
     lentivirus expression plasmids for stable overexpression of TAS2R31
     adenovirus for overexpression of TAS2R31
     LSBio Antibodies in human, mouse, rat for TAS2R31
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TAS2R31 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4