Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TAS2R30 Gene

protein-coding   GIFtS: 40
GCID: GC12M011285

taste receptor, type 2, member 30

(Previous names: taste receptor, type 2, member 47 )
(Previous symbol: TAS2R47)
  Search for TAS2R30
in our new
 Human Malady Compendium 
Biological research products
for TAS2R30
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Taste Receptor, Type 2, Member 301 2     T2R472 3
T2R301 2 3     Taste Receptor T2R472
TAS2R471 2 3     Taste Receptor Type 2 Member 302
Taste Receptor, Type 2, Member 471 2     Type 2 Taste Receptor Member 302
Taste Receptor Type 2 Member 472 3     Type 2 Taste Receptor Member 472

External Ids:    HGNC: 191121   Entrez Gene: 2592932   Ensembl: ENSG000002561887   OMIM: 6139635   UniProtKB: P595413   

Export aliases for TAS2R30 gene to outside databases

Previous GC identifers: GC00U991285 GC12U900765 GC12M011182 GC12M011216


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: T2R30_HUMAN, P59541
Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in
sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha
gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity)

Gene Wiki entry for TAS2R30


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_009714.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TAS2R30 gene promoter:
         Sox5   FOXO3   FOXO3b   FOXC1   POU2F1   FOXO4   POU2F1a   FOXO3a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TAS2R30

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAS2R30


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.2   Ensembl cytogenetic band:  12p13.2   HGNC cytogenetic band: 12p13.2

TAS2R30 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAS2R30 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M011285:  view genomic region     (about GC identifiers)

Start:
11,285,557 bp from pter      End:
11,287,243 bp from pter
Size:
1,687 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: T2R30_HUMAN, P59541 (See protein sequence)
Recommended Name: Taste receptor type 2 member 30  
Size: 319 amino acids; 36792 Da
Subcellular location: Membrane; Multi-pass membrane protein
Miscellaneous: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can
discriminate among bitter stimuli
Secondary accessions: Q645X7

Explore the universe of human proteins at neXtProt for TAS2R30: NX_P59541

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P59541

  • TAS2R30 Protein expression data from MOPED and PaxDb:    About this image 
    TAS2R30 Protein Expression
    REFSEQ proteins: NP_001091112.1  
    ENSEMBL proteins: 
     ENSP00000444736  

    Human Recombinant Protein Products for TAS2R30: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom Protein Services for TAS2R30 
    GenScript Custom Purified and Recombinant Proteins Services for TAS2R30
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TAS2R30

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--

    TAS2R30 for ontologies           About GeneDecksing



    TAS2R30 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TAS2R30 
    GenScript Custom Superior Antibodies Services for TAS2R30
    Novus Biologicals TAS2R30 Antibody
    Abcam antibodies for TAS2R30 
    Uscn Antibodies for TAS2R30
    ThermoFisher Antibodies for TAS2R30

    Assay Products for TAS2R30: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TAS2R30
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for TAS2R30


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TAS2R30 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR007960 TAS2_rcpt

    Graphical View of Domain Structure for InterPro Entry P59541

    ProtoNet protein and cluster: P59541

    UniProtKB/Swiss-Prot: T2R30_HUMAN, P59541
    Similarity: Belongs to the G-protein coupled receptor T2R family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: T2R30_HUMAN, P59541
    Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in
    sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha
    gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity IEA--
         
    TAS2R30 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TAS2R30 

    miRNA
    Products:
        
    Browse 3'-UTR reporter clones for miRNA target validation
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TAS2R30
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TAS2R30
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TAS2R30 (see all 4)
    OriGene shRNA RFP: TAS2R30
    OriGene siRNA: TAS2R30
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TAS2R30
    Sirion Biotech Custom design and validation of potent shRNA sequences against TAS2R30 

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TAS2R30
    Sirion Biotech Customized adenovirus for overexpression of TAS2R30 
    Sirion Biotech Customized adenovirus for potent knockdown of TAS2R30

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAS2R30 (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAS2R30
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TAS2R30 (NM_001097643)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TAS2R30
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAS2R30 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TAS2R30
    Search LifeMap BioReagents cell lines for TAS2R30
    Sirion Biotech Customized stable knockdown cell line services for TAS2R30 
    Sirion Biotech Customized inducible knockdown cell line services for TAS2R30
    Sirion Biotech Customized stable overexpressing cell line services for TAS2R30
    Sirion Biotech Customized inducible overexpressing cell line services for TAS2R30

    In Situ Assay
    Products:
       

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TAS2R30


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Sweet Taste Signaling
    Bitter Taste Signaling0.44

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for TAS2R30
        Bitter Taste Signaling


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TAS2R30

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0050909sensory perception of taste IEA--

    TAS2R30 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TAS2R30

    10 BitterDB Bitter Compounds for TAS2R30 About this table
    CompoundSMILES CAS #
    AbsinthinC[C@H]1[C@@H]2CC[C@](C)(O)[C@@H]3[C@H]4[C@@H]5C=C(C)[C@@]6([C@H]7OC(=O)[C@@H](C)[C@@H]7CC[C@](C)(O)[C@H]56)[C@H]4C(=C3[C@H]2OC1=O)C1362-42-1
    amarogentinOC[C@H]1O[C@@H](O[C@@H]2OC=C3[C@@H](CCOC3=O)[C@H]2C=C)[C@H](OC(=O)c4c(O)cc(O)cc4c5cccc(O)c5)[C@@H](O)[C@@H]1O21018-84-8
    andrographolideC[C@@]1(CO)[C@H](O)CC[C@@]2(C)[C@H](CC=C3/[C@H](O)COC3=O)C(=C)CC[C@H]125508-58-7
    ArtemorinCC1=C/[C@H]2OC(=O)C(=C)[C@@H]2CCC(=C)[C@H](O)CC1--
    CampherCC1(C)C2CCC1(C)C(=O)OC2=O--
    CascarillinC[C@@H]1[C@@H](C[C@]2(C)[C@H](CC[C@@H](O)[C@]2(C)O)[C@]1(C[C@@H](O)c3cocc3)C=O)OC(=O)C10118-56-6
    denatonium benzoateCC[N+](CC)(CC(=O)Nc1c(C)cccc1C)Cc2ccccc2.[O-]C(=O)c3ccccc33734-33-6
    diphenidolOC(CCCN1CCCCC1)(c2ccccc2)c3ccccc3--
    PicrotoxininCC(=C)[C@@H]1[C@H]2OC(=O)[C@@H]1[C@]3(O)C[C@H]4O[C@]45C(=O)O[C@H]2[C@]35C17617-45-7
    QuassinCOC1=C[C@@H](C)[C@@H]2C[C@H]3OC(=O)C[C@H]4C(=C(OC)C(=O)[C@@H]([C@@]34C)[C@@]2(C)C1=O)C76-78-8

    Search CenterWatch for drugs/clinical trials and news about TAS2R30 / T2R30 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TAS2R30 gene: 
    NM_001097643.1  

    Unigene Cluster for TAS2R30:

    Taste receptor, type 2, member 30
    Hs.679464  [show with all ESTs]
    Unigene Representative Sequence: NM_001097643
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000539585(uc009zhs.1)

    miRNA
    Products:
         
    Browse 3'-UTR reporter clones for miRNA target validation
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TAS2R30
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TAS2R30
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TAS2R30 (see all 4)
    OriGene shRNA RFP: TAS2R30
    OriGene siRNA: TAS2R30
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TAS2R30
    Sirion Biotech Custom design and validation of potent shRNA sequences against TAS2R30 
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAS2R30 (see all 2)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAS2R30
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: TAS2R30 (NM_001097643)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TAS2R30
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAS2R30 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TAS2R30
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TAS2R30
      Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAS2R30
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAS2R30

    2 DOTS entries:

    DT.100738199  DT.86859104 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TAS2R30 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGAGGTACTG
    TAS2R30 Expression
    About this image
    See TAS2R30 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.679464

    UniProtKB/Swiss-Prot: T2R30_HUMAN, P59541
    Tissue specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive
    cells

        SABiosciences Custom PCR Arrays for TAS2R30
    Primer
    Products:
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TAS2R30
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TAS2R30
    Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAS2R30
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAS2R30
    In Situ
    Assay Products:
     

     
    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TAS2R30

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TAS2R30 gene from 2/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves Q2AB81_CHICK6
    Taste receptor type 2
    19(a)
    possible ortholog
    3(112675246-112676211)
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    (see all 3)
    --
    26(a)
    21(a)
    (see all 3)
    many ↔ many
    many ↔ many
    (see all 3)
    GL343381.1(254214-512591)
    GL343391.1(165866-166828)


    ENSEMBL Gene Tree for TAS2R30 (if available)
    TreeFam Gene Tree for TAS2R30 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TAS2R30 gene
    TAS2R52  TAS2R412  TAS2R462  TAS2R162  TAS2R32  TAS2R142  TAS2R432  TAS2R392  
    TAS2R382  TAS2R422  TAS2R92  TAS2R42  TAS2R12  TAS2R192  TAS2R72  TAS2R202  
    TAS2R82  TAS2R402  TAS2R102  TAS2R502  TAS2R132  TAS2R602  TAS2R312  
    18/48 SIMAP similar genes for TAS2R30 using alignment to 1 protein entry:     T2R30_HUMAN(see all similar genes):
    Hosa(Biaka)-T2R47    Hosa(Adygei)-T2R46    Hosa(Biaka)-T2R46    TAS2R46    Hosa(Biaka)-T2R43    TAS2R43
    Hosa(Japanese)-T2R45    TAS2R31    TAS2R45    Hosa(Biaka)-T2R48    Hosa(Japanese)-T2R48    TAS2R50
    Hosa(Adygei)-T2R50    Hosa(Biaka)-T2R50    Hosa(Japanese)-T2R50    TAS2R19    Hosa(Adygei)-T2R49    Hosa(Biaka)-T2R49

    TAS2R30 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/108 NCBI SNPs in TAS2R30 are shown (see all 108    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1821364451,2
    --11285431(+) TGAACA/GACCTT 2 -- int1 ds50010--------
    rs724774601,2
    F--11285580(+) ATTCTA/CCAAAT 2 -- int1 ds50012Minor allele frequency- C:0.08NA EA 240
    rs1855193541,2
    --11285586(+) CAAATA/GAAATA 2 -- int1 ds50010--------
    rs2006788801,2
    --11285627(+) ATAAT-/TCTGAGG 2 -- int1 ds50010--------
    rs73137961,2
    C--11285689(+) AAAGCA/CTGTTA 2 -- int1 ds50014Minor allele frequency- C:0.24CSA WA NA EA 360
    rs106456571,2
    C--11285719(+) TTCAT-/ACacaca 2 -- int1 ds50011Minor allele frequency- AC:0.50NA 2
    rs767465451,2
    --11285719(+) TTTCAC/TACACA 2 -- ds5001 int11Minor allele frequency- T:0.50NA 2
    rs25979261,2
    C--11285727(-) TGTGTA/G/TTGTGT 2 -- ds5001 int11NA 2
    rs710550891,2
    C--11285742(+) ACACACA/-TCTAT 2 -- int1 ds50011Minor allele frequency- -:0.00NA 2
    rs1409794021,2
    --11285750(+) TATATA/GTATGT 2 -- int1 ds50010--------

    HapMap Linkage Disequilibrium report for TAS2R30 (11285557 - 11287243 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for TAS2R30
         2 CNVs: 3875 31858

    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TAS2R30
    DNA2.0 Custom Variant and Variant Library Synthesis for TAS2R30

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TAS2R30 for disorders           About MalaCards

    TAS2R30 for disorders           About GeneDecksing

    OMIM gene information: 613963    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for TAS2R30:
    Balkan nephropathy

    Export disorders for TAS2R30 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TAS2R30 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TAS2R30)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Evolution of bitter taste receptors in humans and apes. (PubMed id 15496549)1, 2 Fischer A.... Paeaebo S. (2005)
    2. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. (PubMed id 12581520)1, 2 Zhang Y.... Ryba N.J. (2003)
    3. Molecular mechanisms of bitter and sweet taste transduction. (PubMed id 11696554)1, 2 Margolskee R.F. (2002)
    4. The human TAS2R16 receptor mediates bitter taste in response to beta- glucopyranosides. (PubMed id 12379855)1, 2 Bufe B.... Meyerhof W. (2002)
    5. Receptors for bitter and sweet taste. (PubMed id 12139982)1, 2 Montmayeur J.-P. and Matsunami H. (2002)
    6. Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates. (PubMed id 15744053)1 Go Y.... Takahata N. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 259293 HGNC: 19112 Ensembl:ENSG00000256188 euGenes: HUgn259293 ECgene: TAS2R30
    H-InvDB: TAS2R30

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TAS2R30 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TAS2R30 gene:
    Search GeneIP for patents involving TAS2R30

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for TAS2R30  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TAS2R30   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TAS2R30  
     Browse OriGene Protein Over-expression Lysates   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for TAS2R30   Browse 3'-UTR reporter clones for miRNA target validation  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TAS2R30   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TAS2R30  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TAS2R30   OriGene Custom Protein Services for TAS2R30  
     OriGene Custom Immunoassay Development  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TAS2R30
     Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TAS2R30
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAS2R30
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TAS2R30
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TAS2R30
     Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TAS2R30
     GenScript Custom Purified and Recombinant Proteins Services for TAS2R30 GenScript cDNA clones with any tag delivered in your preferred vector for TAS2R30
     GenScript Custom Assay Services for TAS2R30 GenScript Custom Superior Antibodies Services for TAS2R30
     GenScript Custom overexpressing Cell Line Services for TAS2R30 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in TAS2R30 promoter
     Search Chromatin IP Primers for TAS2R30
     RT2 qPCR Primer Assay in human, mouse / rat TAS2R30
     Search GNC Networks for TAS2R30
     SABiosciences PCR Arrays including human, mouse, rat TAS2R30
     Search Tocris compounds for TAS2R30
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     TAS2R30 antibodies
     Antibodies for TAS2R30
     See all of Abcam's Antibodies, Kits and Proteins for TAS2R30
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     TAS2R30 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for TAS2R30
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for TAS2R30
     Browse SwitchGear 3'UTR luciferase reporter plasmids for TAS2R30
     Browse SwitchGear Promoter luciferase reporter plasmids for TAS2R30
     ThermoFisher Antibodies for TAS2R30
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TAS2R30
     inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TAS2R30
    Sirion Biotech Customized:
     stable knockdown cell line services for TAS2R30
     inducible knockdown cell line services for TAS2R30
     design and validation of potent shRNA sequences against TAS2R30
     adenovirus for potent knockdown of TAS2R30
     adenovirus for overexpression of TAS2R30
     stable overexpressing cell line services for TAS2R30
     inducible overexpressing cell line services for TAS2R30
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TAS2R30 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4