Aliases for TAS2R16 Gene
External Ids for TAS2R16 Gene
Previous GeneCards Identifiers for TAS2R16 Gene
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008]
GeneCards Summary for TAS2R16 Gene
TAS2R16 (Taste 2 Receptor Member 16) is a Protein Coding gene. Diseases associated with TAS2R16 include Alcohol Dependence and Alcohol Use Disorder. Among its related pathways are Peptide ligand-binding receptors and Taste transduction. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and bitter taste receptor activity. An important paralog of this gene is TAS2R41.
UniProtKB/Swiss-Prot for TAS2R16 Gene
Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.