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TAS2R16 Gene

protein-coding   GIFtS: 57
GCID: GC07M122634

Taste Receptor, Type 2, Member 16

  See TAS2R16-related diseases
at
MalaCards
 

Aliases
for TAS2R16 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Taste Receptor, Type 2, Member 161 2
T2R162 3 5
Candidate Taste Receptor T2R162
Taste Receptor Type 2 Member 162

External Ids:    HGNC: 149211   Entrez Gene: 508332   Ensembl: ENSG000001285197   OMIM: 6048675   UniProtKB: Q9NYV73   

Export aliases for TAS2R16 gene to outside databases

Previous GC identifers: GC07M121112 GC07M122175 GC07M122189 GC07M122228 GC07M122421 GC07M116997


Summaries
for TAS2R16 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TAS2R16 Gene:
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled
receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and
palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein,
functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in
chromosome 7 and is genetically linked to loci that influence bitter perception. (provided by RefSeq, Jul 2008)

GeneCards Summary for TAS2R16 Gene:
TAS2R16 (taste receptor, type 2, member 16) is a protein-coding gene. Diseases associated with TAS2R16 include alcohol dependence, and nicotine dependence. GO annotations related to this gene include bitter taste receptor activity. An important paralog of this gene is TAS2R41.

UniProtKB/Swiss-Prot: T2R16_HUMAN, Q9NYV7
Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the
gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5

Gene Wiki entry for TAS2R16 Gene


Genomic Views
for TAS2R16 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NC_018918.2  NT_007933.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the TAS2R16 gene promoter:
         C/EBPbeta   Brachyury   LCR-F1   MEF-2A   POU2F1   POU2F1a   Sox9   Msx-1   aMEF-2   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TAS2R16 promoter sequence
   Search Chromatin IP Primers for TAS2R16

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TAS2R16


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q31.1-q31.3|7q31   Ensembl cytogenetic band:  7q31.32   HGNC cytogenetic band: 7q31.1-q31.3

TAS2R16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAS2R16 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M122634:  view genomic region     (about GC identifiers)

Start:
 122,634,759 bp from pter      End:
 122,635,754 bp from pter
Size:
 996 bases      Orientation:
 minus strand

1 alternative location:
Chr7-,CRA_TCAG 122,023,644-122,024,639     

Proteins
for TAS2R16 gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: T2R16_HUMAN, Q9NYV7 (See protein sequence)
Recommended Name: Taste receptor type 2 member 16  
Size: 291 amino acids; 33986 Da
Miscellaneous: Several bitter taste receptors are expressed in a single taste receptor cell
Miscellaneous: Confers bitter perception of salicin to non-taster mice
Secondary accessions: A4D0X2 Q502V3 Q549U8 Q645W1

Explore the universe of human proteins at neXtProt for TAS2R16: NX_Q9NYV7

Explore proteomics data for TAS2R16 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn80, Asn163
  • Modification sites at PhosphoSitePlus

    • See TAS2R16 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_058641.1  
    ENSEMBL proteins: 
     ENSP00000249284  
    Reactome Protein details: Q9NYV7

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    Cloud-Clone Corp. Proteins for TAS2R16

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         		antibodies-online peptides for TAS2R16

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    antibodies-online kits for TAS2R16 (6 products) 

    Domains /
    Families
    for TAS2R16 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus    		 HGNC Gene Families:
    TASNR: GPCR / Unclassified : Taste receptors
    TAS2R: Taste receptors / Type 2

    IUPHAR Guide to PHARMACOLOGY protein family classification: TAS2R16
    Taste 2 receptors

    1 InterPro protein domain:
     IPR007960 TAS2_rcpt

    Graphical View of Domain Structure for InterPro Entry Q9NYV7

    ProtoNet protein and cluster: Q9NYV7

    UniProtKB/Swiss-Prot: T2R16_HUMAN, Q9NYV7
    Similarity: Belongs to the G-protein coupled receptor T2R family


    Find genes that share domains with TAS2R16           About GenesLikeMe


    Function
    for TAS2R16 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: T2R16_HUMAN, Q9NYV7
    Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the
    gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity ----
    GO:0005515protein binding IPI16720576
    GO:0033038bitter taste receptor activity IDA16720576
         
    Find genes that share ontologies with TAS2R16           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for TAS2R16:
     Increased HPV18 LCR reporter a  Increased gamma-H2AX phosphory 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for TAS2R16

    miRNA
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    Localization
    for TAS2R16 gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    T2R16_HUMAN, Q9NYV7: Membrane; Multi-pass membrane protein
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum4
    plasma membrane4

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005783endoplasmic reticulum IDA16720576
    GO:0005802trans-Golgi network IDA16720576
    GO:0005886plasma membrane TAS--
    GO:0009897external side of plasma membrane IDA16720576
    GO:0016021integral component of membrane IC10761934

    Find genes that share ontologies with TAS2R16           About GenesLikeMe


    Pathways & Interactions
    for TAS2R16 gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TAS2R16 About    
    See pathways by source

    		      Powered
    by    		     
    SuperPathContained pathways About
    1Taste transduction
    		Class C/3 (Metabotropic glutamate/pheromone receptors)0.45
    		Taste transduction0.45
    2Signaling by GPCR
    		Signaling by GPCR0.90
    		Signal Transduction0.58
    		GPCR downstream signaling0.90
    3Peptide ligand-binding receptors
    		GPCR ligand binding0.71
    		G alpha (i) signalling events0.44
    4Sweet Taste Signaling
    		Bitter Taste Signaling0.44


    Find genes that share SuperPaths with TAS2R16           About GenesLikeMe

    Pathways by source                                   See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for TAS2R16
        Bitter Taste Signaling

    2 Reactome Pathways for TAS2R16
        Class C/3 (Metabotropic glutamate/pheromone receptors)
    G alpha (i) signalling events


    1 Kegg Pathway  (Kegg details for TAS2R16):
        Taste transduction

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TAS2R16
    Interactions:

        Search GeneGlobe Interaction Network for TAS2R16

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for TAS2R16 (ENSP000002492844) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GNAT3ENSP000003813394STRING: ENSP00000381339
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001580detection of chemical stimulus involved in sensory perception of bitter taste IDA16720576
    GO:0007186G-protein coupled receptor signaling pathway IC16720576
    GO:0050909sensory perception of taste ----

    Find genes that share ontologies with TAS2R16           About GenesLikeMe



    Drugs & Compounds
    for TAS2R16 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TAS2R16 (T2R16)

    1 HMDB Compound for TAS2R16    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    8 BitterDB Bitter Compounds for TAS2R16    About this table
    CompoundSMILES CAS #
    Amygdalin, DOCC1OC(OCC2OC(OC(C#N)c3ccccc3)C(O)C(O)C2O)C(O)C(O)C1O--
    ArbutinOC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O--
    D-salicin,SalicinOC[C@H]1O[C@@H](Oc2ccccc2CO)[C@H](O)[C@@H](O)[C@@H]1O138-52-3
    diphenidolOC(CCCN1CCCCC1)(c2ccccc2)c3ccccc3--
    HelicinOC[C@H]1O[C@@H](Oc2ccccc2C=O)[C@H](O)[C@@H](O)[C@@H]1O--
    Phenyl beta-D-glucopyranosideOC[C@H]1O[C@@H](Oc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O1464-44-4
    sinigrin[K+].OC[C@H]1O[C@@H](SC(=NOS(=O)(=O)[O-])CC=C)[C@H](O)[C@@H](O)[C@@H]1O--
    Sodium Benzoate[Na+].[O-]C(=O)c1ccccc1--




    Transcripts
    for TAS2R16 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TAS2R16 gene: 
    NM_016945.2  

    Unigene Cluster for TAS2R16:

    Taste receptor, type 2, member 16
    Hs.272395
    Unigene Representative Sequence: NM_016945
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000249284(uc003vkl.1)
    miRNA
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    Additional mRNA sequence: BC095524.1 

    1 DOTS entry:

    DT.91995294 

    2 AceView cDNA sequences:

    NM_016945 CF147792 

    GeneLoc Exon Structure


    Expression
    for TAS2R16 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TAS2R16 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCATCACTGA
    TAS2R16 Expression
    About this image

    TAS2R16 Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    TAS2R16 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.272395

    UniProtKB/Swiss-Prot: T2R16_HUMAN, Q9NYV7
    Tissue specificity: Expressed in a subset of gustducin-positive taste receptor cells of the tongue

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    Orthologs
    for TAS2R16 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TAS2R16 gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Tas2r1181 , 5 taste receptor, type 2, member 1181, 5 70.51(n)1
    53.85(a)1    		   6 (11.18 cM)5
    3873471  NM_207022.11  NP_996905.11 
     239691615 
    chicken
    (Gallus gallus)    		 Aves TAS2R76
    		 Gallus gallus taste receptor, type 2, member 7 (TA...
    		 21(a)
    		 1 → many
    		 3(109476673-109477638)


    ENSEMBL Gene Tree for TAS2R16 (if available)
    TreeFam Gene Tree for TAS2R16 (if available)

    Paralogs
    for TAS2R16 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TAS2R16 gene
    TAS2R412  TAS2R52  TAS2R462  TAS2R32  TAS2R432  TAS2R142  TAS2R392  TAS2R382  
    TAS2R422  TAS2R92  TAS2R42  TAS2R302  TAS2R12  TAS2R192  TAS2R72  TAS2R202  
    TAS2R82  TAS2R102  TAS2R502  TAS2R132  TAS2R402  TAS2R602  TAS2R312  
    17 SIMAP similar genes for TAS2R16 using alignment to 1 protein entry:     T2R16_HUMAN:
    Hosa(Biaka)-T2R16    Hosa(Japanese)-T2R16    Hosa(Biaka)-T2R2    TAS2R41    Hosa(Japanese)-T2R56    TAS2R60
    TAS2R9    Hosa(Adygei)-T2R3    Hosa(Biaka)-T2R3    Hosa(Biaka)-T2R40    Hosa(Biaka)-T2R5    Hosa(Japanese)-T2R40
    Hosa(Japanese)-T2R5    TAS2R1    TAS2R3    TAS2R40    TAS2R5

    Find genes that share paralogs with TAS2R16           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for TAS2R16
    PGOHUM00000233616


    Genomic Variants
    for TAS2R16 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Polymorphic Variants from UniProtKB/Swiss-Prot
    T2R16_HUMAN, Q9NYV7: The Lys-172 polymorphism in TAS2R16 is associated with genetic susceptibility to alcoholism
    [MIM:103780]


    Selected SNPs for TAS2R16 (see all 108)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 7 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs8466641,2,,4
    		C,F,A,Hpathogenic1125983959(-) GAAAAG/TTTTCA 2 K N mis126Minor allele frequency- A:0.00EA NA MN NS WA CSA EU 8062
    rs2017998631,2
    		C--122636478(+) TTTTT-/TCTCTT 1 -- us2k10--------
    rs1141629521,2
    		C,F--125983059(+) AGATAA/GAAGTC 1 -- ds50011Minor allele frequency- G:0.02WA 118
    rs1843232751,2
    		--125983064(+) AAAGTA/CCAGAA 1 -- ds50010--------
    rs668484081,2
    		C,F--125983077(+) AGCCAG/TGGGAT 1 -- ds50016Minor allele frequency- T:0.16NA WA EA 364
    rs1423375011,2
    		C--125983126(+) TGAGG-/GAGAGAG 1 -- ds50010--------
    rs1897411901,2
    		--125983180(+) TTAGTA/GTGGGA 1 -- ds50010--------
    rs104877451,2
    		C,F,H--125983195(-) TGTACC/ACTGAA 1 -- ds500112Minor allele frequency- A:0.01NS EA NA 634
    rs1811863121,2
    		--125983232(+) TCATAC/TTCATG 1 -- ds50010--------
    rs1390769671,2
    		--125983260(+) TCATGA/GGAAGG 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for TAS2R16 (122634759 - 122635754 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TAS2R16:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv524192CNV Gain19592680

    Human Gene Mutation Database (HGMD): TAS2R16
    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing TAS2R16
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    Disorders / Diseases
    for TAS2R16 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus    		 OMIM gene information: 604867   
    OMIM disorders: 103780  
    2 diseases for TAS2R16:    
    About MalaCards
    alcohol dependence    nicotine dependence

    2 inferred disease relationships from the University of Copenhagen DISEASES database for TAS2R16:
    Nicotine dependence     Alcohol dependence

    Find genes that share disorders with TAS2R16           About GenesLikeMe

    Genetic Association Database (GAD): TAS2R16
    Human Genome Epidemiology (HuGE) Navigator: TAS2R16 (3 documents)

    Export disorders for TAS2R16 gene to outside databases

    Publications
    for TAS2R16 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus
    PubMed articles for TAS2R16 gene, integrated from 10 sources (see all 24):
    (articles sorted by number of sources associating them with TAS2R16)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel family of mammalian taste receptors. (PubMed id 10761934)1, 2, 3 Adler E....Zuker C.S. (Cell 2000)
    2. Bitter taste receptor gene polymorphisms are an important factor in the development of nicotine dependence in African Americans. (PubMed id 18524836)1, 4 Mangold J.E....Li M.D. (J. Med. Genet. 2008)
    3. Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin. (PubMed id 17250611)1, 4 Wang J.C....Goate A.M. (Alcohol. Clin. Exp. Res. 2007)
    4. Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. (PubMed id 16385453)1, 2 Hinrichs A.L.... Goate A.M. (Am. J. Hum. Genet. 2006)
    5. The receptors and coding logic for bitter taste. (PubMed id 15759003)1, 2 Mueller K.L....Ryba N.J. (Nature 2005)
    6. Evolution of bitter taste receptors in humans and apes. (PubMed id 15496549)1, 2 Fischer A.... Paeaebo S. (Mol. Biol. Evol. 2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (Nature 2003)
    9. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. (PubMed id 12581520)1, 2 Zhang Y.... Ryba N.J. (Cell 2003)
    10. Receptors for bitter and sweet taste. (PubMed id 12139982)1, 2 Montmayeur J.-P. and Matsunami H. (Curr. Opin. Neurobiol. 2002)

    External Searches for TAS2R16 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
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      Query String
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    NCBI Bookshelf
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    Genome Databases showing TAS2R16 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 50833 HGNC: 14921 AceView: TAS2R16 Ensembl:ENSG00000128519 euGenes: HUgn50833
    ECgene: TAS2R16 Kegg: 50833 H-InvDB: TAS2R16

    Other Databases showing TAS2R16 gene

    (According to HUGE)
    About This Section

    TryGeneCards Plus    		   --

    Specialized Databases showing TAS2R16 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TAS2R16 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TAS2R16 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus    		Patent Information for TAS2R16 gene:
    Search GeneIP for patents involving TAS2R16

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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