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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TAS2R16 Gene

protein-coding GIFtS: 57
GCID: GC07M122634

Taste Receptor, Type 2, Member 16

3 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
Taste Receptor, Type 2, Member 16¹ ²
T2R16² ³ ⁵
Candidate Taste Receptor T2R16²
Taste Receptor Type 2 Member 16²

External Ids:	HGNC: 14921¹	Entrez Gene: 50833²	Ensembl: ENSG00000128519⁷	OMIM: 604867⁵	UniProtKB: Q9NYV7³

Export aliases for TAS2R16 gene to outside databases

Previous GC identifers: GC07M121112 GC07M122175 GC07M122189 GC07M122228 GC07M122421 GC07M116997

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TAS2R16 Gene:

This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor

superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate

epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a

bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is

genetically linked to loci that influence bitter perception. (provided by RefSeq, Jul 2008)

GeneCards Summary for TAS2R16 Gene:

TAS2R16 (taste receptor, type 2, member 16) is a protein-coding gene. Diseases associated with TAS2R16 include nicotine dependence, and alcohol dependence, and among its related super-pathways are Taste transduction and Signaling by GPCR. GO annotations related to this gene include protein binding and bitter taste receptor activity. An important paralog of this gene is TAS2R41.

UniProtKB/Swiss-Prot: T2R16_HUMAN, Q9NYV7

Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the

gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5

Gene Wiki entry for TAS2R16 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000007.13 NC_018918.2 NT_007933.15 NT_079596.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TAS2R16 gene promoter:
C/EBPbeta Brachyury LCR-F1 MEF-2A POU2F1 POU2F1a Sox9 Msx-1 aMEF-2 Pax-4a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TAS2R16 promoter sequence

Search SABiosciences Chromatin IP Primers for TAS2R16

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAS2R16

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q31.1-q31.3|7q31 Ensembl cytogenetic band: 7q31.32 HGNC cytogenetic band: 7q31.1-q31.3

TAS2R16 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAS2R16 gene location

GeneLoc information about chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M122634: view genomic region (about GC identifiers)

Start:	122,634,759 bp from pter	End:	122,635,754 bp from pter
Size:	996 bases	Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 122,023,644-122,024,639

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: T2R16_HUMAN, Q9NYV7 (See protein sequence)

Recommended Name: Taste receptor type 2 member 16

Size: 291 amino acids; 33986 Da

Subcellular location: Membrane; Multi-pass membrane protein

Miscellaneous: Several bitter taste receptors are expressed in a single taste receptor cell

Miscellaneous: Confers bitter perception of salicin to non-taster mice

Secondary accessions: A4D0X2 Q502V3 Q549U8 Q645W1

Explore the universe of human proteins at neXtProt for TAS2R16: NX_Q9NYV7

Explore proteomics data for TAS2R16 at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q9NYV7

TAS2R16 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_058641.1

ENSEMBL proteins:

ENSP00000249284

Reactome Protein details: Q9NYV7
Human Recombinant Protein Products for TAS2R16:

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	Cloud-Clone Corp. Proteins for TAS2R16

Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005783	endoplasmic reticulum	IDA	16720576
GO:0005802	trans-Golgi network	IDA	16720576
GO:0005886	plasma membrane	TAS	--
GO:0009897	external side of plasma membrane	IDA	16720576
GO:0016021	integral to membrane	IC	10761934

TAS2R16 for ontologies About GeneDecksing

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

HGNC Gene Families:

TASNR: GPCR / Unclassified : Taste receptors

TAS2R: Taste receptors / Type 2

IUPHAR Guide to PHARMACOLOGY protein family classification: TAS2R16

Taste 2 receptors

1 InterPro protein domain:

IPR007960 TAS2_rcpt

Graphical View of Domain Structure for InterPro Entry Q9NYV7

ProtoNet protein and cluster: Q9NYV7

UniProtKB/Swiss-Prot: T2R16_HUMAN, Q9NYV7

Similarity: Belongs to the G-protein coupled receptor T2R family

TAS2R16 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: T2R16_HUMAN, Q9NYV7

Function: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the

gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004930	G-protein coupled receptor activity	--	--
GO:0005515	protein binding	IPI	16720576
GO:0033038	bitter taste receptor activity	IDA	16720576

TAS2R16 for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for TAS2R16:

Increased HPV18 LCR reporter a

Increased gamma-H2AX phosphory

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for TAS2R16

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TAS2R16

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAS2R16

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for TAS2R16 About

See pathways by source

SuperPath

Contained pathways About

Class C/3 (Metabotropic glutamate/pheromone receptors)

Class C/3 (Metabotropic glutamate/pheromone receptors)

0.45

Taste transduction

0.45

Signaling by GPCR

	Signaling by GPCR	0.90			Signal Transduction	0.55
	GPCR downstream signaling	0.90

Class A/1 (Rhodopsin-like receptors)

GPCR ligand binding

0.71

G alpha (i) signalling events

0.46

Sweet Taste Signaling

Bitter Taste Signaling

0.44

Pathways by source See SuperPaths
Show all pathways

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for TAS2R16

Bitter Taste Signaling

5/6 Reactome Pathways for TAS2R16 (see all 6)

	GPCR downstream signaling
	Signal Transduction
	Class C/3 (Metabotropic glutamate/pheromone receptors)
	Signaling by GPCR
	G alpha (i) signalling events

1 Kegg Pathway (Kegg details for TAS2R16):

Taste transduction

TAS2R16 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TAS2R16

STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

1 Interacting protein for TAS2R16 (ENSP00000249284⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GNAT3	ENSP00000381339⁴	STRING: ENSP00000381339

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste	IDA	16720576
GO:0007186	G-protein coupled receptor signaling pathway	IC	16720576
GO:0050909	sensory perception of taste	--	--

TAS2R16 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TAS2R16 (T2R16)

1 HMDB Compound for TAS2R16 About this table

Compound	Synonyms	CAS #	PubMed Ids
Calcium	Ca (see all 2)	7440-70-2	--

8 BitterDB Bitter Compounds for TAS2R16

About this table

Compound	SMILES	CAS #
Amygdalin, D	OCC1OC(OCC2OC(OC(C#N)c3ccccc3)C(O)C(O)C2O)C(O)C(O)C1O	--
Arbutin	OC[C@H]1O[C@@H](Oc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O	--
D-salicin,Salicin	OC[C@H]1O[C@@H](Oc2ccccc2CO)[C@H](O)[C@@H](O)[C@@H]1O	138-52-3
diphenidol	OC(CCCN1CCCCC1)(c2ccccc2)c3ccccc3	--
Helicin	OC[C@H]1O[C@@H](Oc2ccccc2C=O)[C@H](O)[C@@H](O)[C@@H]1O	--
Phenyl beta-D-glucopyranoside	OC[C@H]1O[C@@H](Oc2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O	1464-44-4
sinigrin	[K+].OC[C@H]1O[C@@H](SC(=NOS(=O)(=O)[O-])CC=C)[C@H](O)[C@@H](O)[C@@H]1O	--
Sodium Benzoate	[Na+].[O-]C(=O)c1ccccc1	--

Search CenterWatch for drugs/clinical trials and news about TAS2R16 / T2R16

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TAS2R16 gene:

NM_016945.2

Unigene Cluster for TAS2R16:

Taste receptor, type 2, member 16

Hs.272395

Unigene Representative Sequence: NM_016945

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000249284(uc003vkl.1)

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Additional mRNA sequence: BC095524.1

1 DOTS entry:

DT.91995294

2 AceView cDNA sequences:

CF147792 NM_016945

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TAS2R16 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GCATCACTGA

About this image

See TAS2R16 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TAS2R16

SOURCE GeneReport for Unigene cluster: Hs.272395

UniProtKB/Swiss-Prot: T2R16_HUMAN, Q9NYV7

Tissue specificity: Expressed in a subset of gustducin-positive taste receptor cells of the tongue

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for TAS2R16 gene from 4/10 species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Tas2r118^{1 , 5}	taste receptor, type 2, member 118^{1, 5}	70.51(n)¹ 53.85(a)¹		6 (11.18 cM)⁵ 387347¹ NM_207022.1¹ NP_996905.1¹ 23969161⁵
chicken (Gallus gallus)	Aves	TAS2R7⁶	taste receptor type 2 member 7	21(a)	possible ortholog	3(109476673-109477638)
lizard (Anolis carolinensis)	Reptilia	-- -- (see all 3)	Taste receptor type 2 (see all 3)	29(a) 21(a) (see all 3)	many ↔ many many ↔ many (see all 3)	GL343381.1(254214-512591) GL343391.1(165866-166828)
zebrafish (Danio rerio)	Actinopterygii	tas2r200.1⁶ tas2r200.2⁶	taste receptor, type 2, member 200.2	14(a) 14(a)	many ↔ many many ↔ many	8(31631970-31633062) 8(31629027-31630131)

ENSEMBL Gene Tree for TAS2R16 (if available)
TreeFam Gene Tree for TAS2R16 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TAS2R16 gene

TAS2R41² TAS2R5² TAS2R46² TAS2R3² TAS2R43² TAS2R14² TAS2R39² TAS2R38²

TAS2R42² TAS2R9² TAS2R4² TAS2R30² TAS2R1² TAS2R19² TAS2R7² TAS2R20²

TAS2R8² TAS2R10² TAS2R50² TAS2R13² TAS2R40² TAS2R60² TAS2R31²

17 SIMAP similar genes for TAS2R16 using alignment to 1 protein entry: T2R16_HUMAN:

Hosa(Biaka)-T2R16 Hosa(Japanese)-T2R16 Hosa(Biaka)-T2R2 TAS2R41 Hosa(Japanese)-T2R56 TAS2R60

TAS2R9 Hosa(Adygei)-T2R3 Hosa(Biaka)-T2R3 Hosa(Biaka)-T2R40 Hosa(Biaka)-T2R5 Hosa(Japanese)-T2R40

Hosa(Japanese)-T2R5 TAS2R1 TAS2R3 TAS2R40 TAS2R5

TAS2R16 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for TAS2R16
PGOHUM00000233616

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

UniProtKB/Swiss-Prot: T2R16_HUMAN, Q9NYV7

Polymorphism: The Lys-172 polymorphism in TAS2R16 is associated with genetic susceptibility to alcoholism [MIM:103780]

SNP ID	Valid	Clinical significance	Chr 7 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs846664^1,2,4	C,F,A,H	pathogenic¹	125983959(-)	`GAAAAG/TTTTCA`	2	K N	mis¹		26		EA NA MN NS WA CSA EU	8062
rs201799863^1,2	C	--	122636478(+)	`TTTTT-/TCTCTT`	1	--	us2k¹		0	--	--	--	--
rs114162952^1,2	C,F	--	125983059(+)	`AGATAA/GAAGTC`	1	--	ds500¹		1		WA	118
rs184323275^1,2		--	125983064(+)	`AAAGTA/CCAGAA`	1	--	ds500¹		0	--	--	--	--
rs66848408^1,2	C,F	--	125983077(+)	`AGCCAG/TGGGAT`	1	--	ds500¹		6		NA WA EA	364
rs142337501^1,2	C	--	125983126(+)	`TGAGG-/GAGAGAG`	1	--	ds500¹		0	--	--	--	--
rs189741190^1,2		--	125983180(+)	`TTAGTA/GTGGGA`	1	--	ds500¹		0	--	--	--	--
rs10487745^1,2	C,F,H	--	125983195(-)	`TGTACC/ACTGAA`	1	--	ds500¹		12		NS EA NA	634
rs181186312^1,2		--	125983232(+)	`TCATAC/TTCATG`	1	--	ds500¹		0	--	--	--	--
rs139076967^1,2		--	125983260(+)	`TCATGA/GGAAGG`	1	--	ds500¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TAS2R16 (122634759 - 122635754 bp)

Structural Variations
Database of Genomic Variants (DGV) 1 variation for TAS2R16: About this table

Variant ID	Type	Subtype	PubMed ID
nsv524192	CNV	Gain	19592680

Human Gene Mutation Database (HGMD): TAS2R16

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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TAS2R16 for disorders           About GeneDecksing

OMIM gene information: 604867
OMIM disorders: 103780
3 diseases for TAS2R16:    About MalaCards

nicotine dependence alcohol dependence alcoholism

2 diseases from the University of Copenhagen DISEASES database for TAS2R16:

Nicotine dependence Alcohol dependence

Genetic Association Database (GAD): TAS2R16
Human Genome Epidemiology (HuGE) Navigator: TAS2R16 (3 documents)

Export disorders for TAS2R16 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for TAS2R16 gene, integrated from 9 sources (see all 24):
(articles sorted by number of sources associating them with TAS2R16)

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A novel family of mammalian taste receptors. (PubMed id 10761934)^{1, 2, 3} Adler E....Zuker C.S. (2000)
Bitter taste receptor gene polymorphisms are an important factor in the development of nicotine dependence in African Americans. (PubMed id 18524836)^{1, 4} Mangold J.E....Li M.D. (2008)
Functional variants in TAS2R38 and TAS2R16 influence alcohol consumption in high-risk families of African-American origin. (PubMed id 17250611)^{1, 4} Wang J.C....Goate A.M. (2007)
Functional variant in a bitter-taste receptor (hTAS2R16) influences risk of alcohol dependence. (PubMed id 16385453)^{1, 2} Hinrichs A.L.... Goate A.M. (2006)
The receptors and coding logic for bitter taste. (PubMed id 15759003)^{1, 2} Mueller K.L....Ryba N.J. (2005)
Evolution of bitter taste receptors in humans and apes. (PubMed id 15496549)^{1, 2} Fischer A.... Paeaebo S. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{1, 2} Hillier L.W.... Wilson R.K. (2003)
Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. (PubMed id 12581520)^{1, 2} Zhang Y.... Ryba N.J. (2003)
Receptors for bitter and sweet taste. (PubMed id 12139982)^{1, 2} Montmayeur J.-P. and Matsunami H. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 50833	HGNC: 14921	AceView: TAS2R16	Ensembl:ENSG00000128519	euGenes: HUgn50833
ECgene: TAS2R16	Kegg: 50833	H-InvDB: TAS2R16

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for TAS2R16	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TAS2R16 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TAS2R16 gene:
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GeneCards and IP:
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TAS2R16 Gene

Taste Receptor, Type 2, Member 16

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TAS2R16 Gene

Taste Receptor, Type 2, Member 16

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