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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TAS2R1 Gene

protein-coding   GIFtS: 54
GCID: GC05M009630

Taste Receptor, Type 2, Member 1

  Search for TAS2R1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Taste Receptor, Type 2, Member 11 2
T2R12 3 5
TRB72 3 5
Taste Receptor Family B Member 72 3
Taste Receptor Type 2 Member 12
Taste Receptor, Family B, Member 72

External Ids:    HGNC: 149091   Entrez Gene: 508342   Ensembl: ENSG000001697777   OMIM: 6047965   UniProtKB: Q9NYW73   

Export aliases for TAS2R1 gene to outside databases

Previous GC identifers: GC05M009797 GC05M009661 GC05M009681 GC05M009682 GC05M009612


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TAS2R1 Gene:
This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled
receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate
epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a
bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that
controls the detection of the bitter compound 6-n-propyl-2-thiouracil. (provided by RefSeq, Jul 2008)

GeneCards Summary for TAS2R1 Gene: 
TAS2R1 (taste receptor, type 2, member 1) is a protein-coding gene. Among its related super-pathways are Taste transduction and Signaling by GPCR. GO annotations related to this gene include taste receptor activity. An important paralog of this gene is TAS2R41.

UniProtKB/Swiss-Prot: TA2R1_HUMAN, Q9NYW7
Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role
in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate
alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5

Gene Wiki entry for TAS2R1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_006576.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TAS2R1 gene promoter:
         AML1a   AP-1   Lmo2   NF-E2 p45   FOXL1   AREB6   IRF-7A   NF-E2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTAS2R1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TAS2R1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TAS2R1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5p15   Ensembl cytogenetic band:  5p15.31   HGNC cytogenetic band: 5p15

TAS2R1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TAS2R1 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05M009630:  view genomic region     (about GC identifiers)

Start:
9,629,109 bp from pter      End:
9,712,490 bp from pter
Size:
83,382 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TA2R1_HUMAN, Q9NYW7 (See protein sequence)
Recommended Name: Taste receptor type 2 member 1  
Size: 299 amino acids; 34333 Da
Subcellular location: Membrane; Multi-pass membrane protein
Miscellaneous: Most taste cells may be activated by a limited number of bitter compounds; individual taste cells
can discriminate among bitter stimuli
Secondary accessions: Q646G8

Explore the universe of human proteins at neXtProt for TAS2R1: NX_Q9NYW7

Explore proteomics data for TAS2R1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NYW7

  • TAS2R1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TAS2R1 Protein Expression
    REFSEQ proteins: NP_062545.1  
    ENSEMBL proteins: 
     ENSP00000476190   ENSP00000475387   ENSP00000371932  
    Reactome Protein details: Q9NYW7
    Human Recombinant Protein Products for TAS2R1: 
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    Cloud-Clone Corp. Proteins for TAS2R1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0016021integral to membrane NAS--

    TAS2R1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TASNR: GPCR / Unclassified : Taste receptors
    TAS2R: Taste receptors / Type 2

    IUPHAR Guide to PHARMACOLOGY protein family classification: TAS2R1 
    Taste 2 receptors

    1 InterPro protein domain:
     IPR007960 TAS2_rcpt

    Graphical View of Domain Structure for InterPro Entry Q9NYW7

    ProtoNet protein and cluster: Q9NYW7

    UniProtKB/Swiss-Prot: TA2R1_HUMAN, Q9NYW7
    Similarity: Belongs to the G-protein coupled receptor T2R family


    TAS2R1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TA2R1_HUMAN, Q9NYW7
    Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role
    in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate
    alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity ----
    GO:0008527taste receptor activity TAS10761934
         
    TAS2R1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for TAS2R1:
     Decreased Hepatitis C virus re  Increased gamma-H2AX phosphory 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TAS2R1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Class C/3 (Metabotropic glutamate/pheromone receptors)
    Class C/3 (Metabotropic glutamate/pheromone receptors)0.45
    Taste transduction0.45
    2Signaling by GPCR
    Signaling by GPCR0.90
    Signal Transduction0.55
    GPCR downstream signaling0.90
    3Class A/1 (Rhodopsin-like receptors)
    GPCR ligand binding0.71
    G alpha (i) signalling events0.46
    4Sweet Taste Signaling
    Bitter Taste Signaling0.44

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for TAS2R1
        Bitter Taste Signaling

    5/6        Reactome Pathways for TAS2R1 (see all 6)
        GPCR downstream signaling
    Signal Transduction
    Class C/3 (Metabotropic glutamate/pheromone receptors)
    Signaling by GPCR
    G alpha (i) signalling events


    1         Kegg Pathway  (Kegg details for TAS2R1):
        Taste transduction


    TAS2R1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TAS2R1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for TAS2R1 (ENSP000003719324) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GNAT3ENSP000003813394STRING: ENSP00000381339
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway TAS10761934
    GO:0007635chemosensory behavior TAS10761934
    GO:0050909sensory perception of taste ----
    GO:0050912detection of chemical stimulus involved in sensory perception of taste TAS10761934

    TAS2R1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TAS2R1 (TA2R1)

    10/27 BitterDB Bitter Compounds for TAS2R1 (see all 27) About this table
    CompoundSMILES CAS #
    AdhumuloneCCC(C)C(=O)C1=C(O)C(O)(CC=C(C)C)C(=O)C(CC=C(C)C)C1=O--
    AdlupuloneCC[C@H](C)C(=O)C1=C(O)C(CC=C(C)C)(CC=C(C)C)C(=O)C(=C1O)CC=C(C)C--
    amarogentinOC[C@H]1O[C@@H](O[C@@H]2OC=C3[C@@H](CCOC3=O)[C@H]2C=C)[C@H](OC(=O)c4c(O)cc(O)cc4c5cccc(O)c5)[C@@H](O)[C@@H]1O21018-84-8
    ArborescinCC1C2CCC3(C)OC34CC=C(C)C4C2OC1=O--
    CascarillinC[C@@H]1[C@@H](C[C@]2(C)[C@H](CC[C@@H](O)[C@]2(C)O)[C@]1(C[C@@H](O)c3cocc3)C=O)OC(=O)C10118-56-6
    chloramphenicolOC[C@@H](NC(=O)C(Cl)Cl)[C@H](O)c1ccc(cc1)[N+](=O)[O-]--
    cis-isocohumuloneCC(C)C(=O)C1=C(O)[C@](O)([C@H](CC=C(C)C)C1=O)C(=O)CC=C(C)C--
    cis-isohumuloneCC(C)CC(=O)C1=C(O)[C@](O)([C@H](CC=C(C)C)C1=O)C(=O)CC=C(C)C--
    cis-isoloadhumuloneCC[C@H](C)C(=O)C1=C(O)[C@](O)([C@H](CC=C(C)C)C1=O)C(=O)CC=C(C)C--
    CohumuloneCC(C)C(=O)C1=C(O)C(=C(O)C(O)(CC=C(C)C)C1=O)CC=C(C)C--


    Search CenterWatch for drugs/clinical trials and news about TAS2R1 / TA2R1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TAS2R1 gene: 
    NM_019599.2  

    Unigene Cluster for TAS2R1:

    Taste receptor, type 2, member 1
    Hs.567492  [show with all ESTs]
    Unigene Representative Sequence: NM_019599
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000514078 ENST00000506620 ENST00000382492(uc003jem.1)
    miRNA
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    Additional mRNA sequence: 

    BC095521.1 BC101729.1 BC101731.1 

    1 DOTS entry:

    DT.102822724 

    21 AceView cDNA sequences:

    NM_019599 BG192000 CN835432 BX112217 CN839897 CN835406 CN843110 AF009306 
    CN835918 CN836511 CN839536 CN835976 CN839562 AI190879 AI191595 BG209561 
    AA416581 BG203110 BX090205 CN836616 CN843196 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TAS2R1 expression in normal human tissues (normalized intensities)      TAS2R1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCCCTTCAG
    TAS2R1 Expression
    About this image


    TAS2R1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Umbilical Cord (Extraembryonic Tissues)
             Umbilical cord blood-derived hematopoietic stem cells
     
     Blood (Hematopoietic System)
             Umbilical cord blood-derived hematopoietic stem cells

    See TAS2R1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TAS2R1

    SOURCE GeneReport for Unigene cluster: Hs.567492

    UniProtKB/Swiss-Prot: TA2R1_HUMAN, Q9NYW7
    Tissue specificity: Expressed in subsets of taste receptor cells of the tongue and palate epithelium and
    exclusively in gustducin-positive cells

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TAS2R1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TAS2R1 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tas2r1191 , 5 taste receptor, type 2, member 1191, 5 66.21(n)1
    51.86(a)1
      15 (13.02 cM)5
    572541  NM_020503.21  NP_065249.21 
     321772895 
    chicken
    (Gallus gallus)
    Aves TAS2R76
    taste receptor type 2 member 7
    23(a)
    possible ortholog
    3(109476673-109477638)
    zebrafish
    (Danio rerio)
    Actinopterygii tas2r200.26
    tas2r200.16
    taste receptor, type 2, member 200.1
    15(a)
    14(a)
    many ↔ many
    many ↔ many
    8(31629027-31630131)
    8(31631970-31633062)


    ENSEMBL Gene Tree for TAS2R1 (if available)
    TreeFam Gene Tree for TAS2R1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TAS2R1 gene
    TAS2R412  TAS2R52  TAS2R462  TAS2R162  TAS2R32  TAS2R432  TAS2R142  TAS2R392  
    TAS2R382  TAS2R422  TAS2R92  TAS2R42  TAS2R302  TAS2R192  TAS2R72  TAS2R202  
    TAS2R82  TAS2R102  TAS2R502  TAS2R132  TAS2R402  TAS2R602  TAS2R312  
    18/58 SIMAP similar genes for TAS2R1 using alignment to 2 protein entries:     TA2R1_HUMAN (see all proteins) (see all similar genes):
    Hosa(Biaka)-T2R1    Hosa(Japanese)-T2R1    Hosa(Biaka)-T2R55    TAS2R42    Hosa(Biaka)-T2R13    Hosa(Japanese)-T2R13
    Hosa(Japanese)-T2R39    TAS2R39    TAS2R7    TAS2R13    Hosa(Adygei)-T2R7    Hosa(Biaka)-T2R2
    Hosa(Biaka)-T2R40    Hosa(Biaka)-T2R7    TAS2R40    Hosa(Japanese)-T2R40    TAS2R10    Hosa(Adygei)-T2R55

    TAS2R1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/117 SNPs in TAS2R1 are shown (see all 117)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1432741511,2
    --9628660(+) AGAAGG/TCCTGC 1 -- ds50010--------
    rs1512550661,2
    --9628696(+) AGGAGA/GAAGAA 1 -- ds50010--------
    rs1817602031,2
    --9628858(+) CATCAC/TGAGTT 1 -- ds50010--------
    rs1155598481,2
    C,F--9628994(+) TTGCAC/AGATGA 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1862772211,2
    --9629024(+) GGATAC/TTGAAA 1 -- ds50010--------
    rs1172325051,2
    C,F--9629126(+) AAACAG/AGCCTG 1 -- ut311Minor allele frequency- A:0.05EA 120
    rs1889315081,2
    --9629169(+) GCTTTA/G/TTCTGG 2 -- ut310--------
    rs1816799931,2
    C--9629223(+) GTTCTC/TTGAAC 1 -- ut310--------
    rs1404426511,2
    C--9629253(+) CTGACA/TGCACT 2 S C mis10--------
    rs22342351,2
    C,F,O,H--9629295(-) CTAAAT/CTGAAA 2 /L syn116Minor allele frequency- C:0.03NS EA NA EU 7933

    HapMap Linkage Disequilibrium report for TAS2R1 (9629109 - 9712490 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TAS2R1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv881438CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TAS2R1 for disorders           About MalaCards
    OMIM gene information: 604796    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for TAS2R1:
    Autistic disorder

    TAS2R1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TAS2R1
    Human Genome Epidemiology (HuGE) Navigator: TAS2R1 (2 documents)

    Export disorders for TAS2R1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TAS2R1 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with TAS2R1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A novel family of mammalian taste receptors. (PubMed id 10761934)1, 2, 3 Adler E....Zuker C.S. (2000)
    2. A genome-wide linkage and association scan reveals no vel loci for autism. (PubMed id 19812673)1, 4 Weiss L.A. and Arking D.E. (2009)
    3. Evolution of bitter taste receptors in humans and apes. (PubMed id 15496549)1, 2 Fischer A.... Paeaebo S. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. (PubMed id 12581520)1, 2 Zhang Y.... Ryba N.J. (2003)
    6. Receptors for bitter and sweet taste. (PubMed id 12139982)1, 2 Montmayeur J.-P. and Matsunami H. (2002)
    7. Molecular mechanisms of bitter and sweet taste transduction. (PubMed id 11696554)1, 2 Margolskee R.F. (2002)
    8. T2Rs function as bitter taste receptors. (PubMed id 10761935)1, 2 Chandrashekar J.... Ryba N.J.P. (2000)
    9. A family of candidate taste receptors in human and mo use. (PubMed id 10766242)1, 3 Matsunami H....Buck L.B. (2000)
    10. Genome-wide association study of HLA-DQB1*06:02 negati ve essential hypersomnia. (PubMed id 23646285)1 Khor S.S....Tokunaga K. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 50834 HGNC: 14909 AceView: TAS2R1 Ensembl:ENSG00000169777 euGenes: HUgn50834
    ECgene: TAS2R1 Kegg: 50834 H-InvDB: TAS2R1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TAS2R1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TAS2R1 gene:
    Search GeneIP for patents involving TAS2R1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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