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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TARSL2 Gene

protein-coding   GIFtS: 52
GCID: GC15M102193

Threonyl-TRNA Synthetase-Like 2

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Threonyl-TRNA Synthetase-Like 21 2     Probable Threonyl-TRNA Synthetase 2, Cytoplasmic2
Threonyl-TRNA Synthetase2 3     thrRS2
Threonyl-TRNA Synthetase-Like Protein 22 3     Threonine--TRNA Ligase2
EC 6.1.1.33 8     ThrRS3
Probable Threonine--TRNA Ligase 2, Cytoplasmic2     

External Ids:    HGNC: 247281   Entrez Gene: 1232832   Ensembl: ENSG000001854187   UniProtKB: A2RTX53   

Export aliases for TARSL2 gene to outside databases

Previous GC identifers: GC15M100013 GC15M078317


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TARSL2 Gene: 
TARSL2 (threonyl-tRNA synthetase-like 2) is a protein-coding gene. Diseases associated with TARSL2 include pneumonia, and tuberculosis, and among its related super-pathways are tRNA Aminoacylation. GO annotations related to this gene include molecular_function and threonine-tRNA ligase activity. An important paralog of this gene is TARS2.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NT_010274.17  NC_018926.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TARSL2 gene promoter:
         c-Fos   AP-1   ATF-2   NCX/Ncx   POU3F2 (N-Oct-5a)   POU3F2 (N-Oct-5b)   POU3F2   RORalpha2   Evi-1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTARSL2 promoter sequence
   Search SABiosciences Chromatin IP Primers for TARSL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TARSL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q26.3   Ensembl cytogenetic band:  15q26.3   HGNC cytogenetic band: 15q26.3

TARSL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TARSL2 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M102193:  view genomic region     (about GC identifiers)

Start:
102,193,801 bp from pter      End:
102,264,807 bp from pter
Size:
71,007 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SYTC2_HUMAN, A2RTX5 (See protein sequence)
Recommended Name: Probable threonine--tRNA ligase 2, cytoplasmic  
Size: 802 amino acids; 92646 Da
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=BAB71554.1; Type=Erroneous initiation;
Secondary accessions: B2RMP7 Q6B0A1 Q6IS76 Q96LW3 Q96MP4
Alternative splicing: 2 isoforms:  A2RTX5-1   A2RTX5-2   

Explore the universe of human proteins at neXtProt for TARSL2: NX_A2RTX5

Explore proteomics data for TARSL2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A2RTX5

  • 4/33 DME Specific Peptides for TARSL2 (A2RTX5) (see all 33)
     WKTTPYQ  IKDAIGR  LCYGPPI  LKPMNCP 

    TARSL2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TARSL2 Protein Expression
    REFSEQ proteins: NP_689547.2  
    ENSEMBL proteins: 
     ENSP00000338093   ENSP00000452740   ENSP00000439899  

    Human Recombinant Protein Products for TARSL2: 
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    Cloud-Clone Corp. Proteins for TARSL2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005737cytoplasm IEA--

    TARSL2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/9 InterPro protein domains (see all 9):
     IPR018163 Thr/Ala-tRNA-synth_IIc_edit
     IPR002314 aa-tRNA-synt_IIb_cons-dom
     IPR002320 Thr-tRNA-ligase_IIa
     IPR012675 Beta-grasp_dom
     IPR006195 aa-tRNA-synth_II

    Graphical View of Domain Structure for InterPro Entry A2RTX5

    ProtoNet protein and cluster: A2RTX5

    UniProtKB/Swiss-Prot: SYTC2_HUMAN, A2RTX5
    Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family


    TARSL2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYTC2_HUMAN, A2RTX5
    Catalytic activity: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr)

         Enzyme Number (IUBMB): EC 6.1.1.31 2

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0003674molecular_function ND--
    GO:0004812aminoacyl-tRNA ligase activity ----
    GO:0004829threonine-tRNA ligase activity IEA--
    GO:0005524ATP binding IEA--
         
    TARSL2 for ontologies           About GeneDecksing


    Animal Models:
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TARSL2 
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    SwitchGear 3'UTR luciferase reporter plasmidTARSL2 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TARSL2


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TARSL2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1tRNA Aminoacylation
    Aminoacyl-tRNA biosynthesis0.54

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for TARSL2):
        Aminoacyl-tRNA biosynthesis


    TARSL2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TARSL2

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/8 Interacting proteins for TARSL2 (A2RTX53 ENSP000003380934) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRKAB1Q9Y4783, ENSP000002293284I2D: score=1 STRING: ENSP00000229328
    C12orf44Q9BSB43I2D: score=1 
    DDA1Q9BW613I2D: score=1 
    GBASO753233I2D: score=1 
    TRAF6Q9Y4K33I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006418tRNA aminoacylation for protein translation ----
    GO:0006435threonyl-tRNA aminoacylation IEA--
    GO:0008150biological_process ND--
    GO:0043039tRNA aminoacylation ----

    TARSL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TARSL2 (SYTC2)

    5 HMDB Compounds for TARSL2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    L-Threonine(2S,3R)-(-)-Threonine (see all 21)72-19-5--
    Phosphoric acidacide phosphorique (FRENCH) (see all 20)7664-38-2--
    Pyrophosphate(4-)Diphosphoric acid ion (see all 10)14000-31-8--

    Search CenterWatch for drugs/clinical trials and news about TARSL2 / SYTC2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TARSL2 gene: 
    NM_152334.2  

    Unigene Cluster for TARSL2:

    Threonyl-tRNA synthetase-like 2
    Hs.657163  [show with all ESTs]
    Unigene Representative Sequence: NM_152334
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000335968(uc002bxl.3 uc002bxm.3 uc010usi.2) ENST00000558533
    ENST00000539112 ENST00000559492 ENST00000557811 ENST00000560150
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
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    8/9 QIAGEN miScript miRNA Assays for microRNAs that regulate TARSL2 (see all 9):
    hsa-miR-4303 hsa-miR-577 hsa-miR-4324 hsa-miR-561 hsa-miR-513a-3p hsa-miR-4261 hsa-miR-3613-3p hsa-miR-4302
    SwitchGear 3'UTR luciferase reporter plasmidTARSL2 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TARSL2
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TARSL2

    Additional mRNA sequence: 

    AK056653.1 AK057734.1 AL833188.1 BC035827.1 BC069346.1 BC069811.1 BC074887.2 BC132671.1 
    BC136315.1 BC143943.1 

    6 DOTS entries:

    DT.100744610  DT.97789090  DT.112531  DT.91885764  DT.95329347  DT.97782147 

    24/75 AceView cDNA sequences (see all 75):

    AW955745 AI341514 AI865427 AI766284 AI094304 CF272335 BU736642 H79277 
    NM_152334 CB127224 BC074887 BC069346 BU618787 BX500769 AL833188 BQ029962 
    N39246 BU677165 BC069811 BF172505 BI255004 AW157764 BM704475 AW157612 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TARSL2    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22a · 22b
    SP1:                                                                                                        -     -     -                                 
    SP2:                          -     -     -     -                                                           -     -     -                                 
    SP3:                                                                                                              -     -           -                     
    SP4:                                                                                                                                                      


    ECgene alternative splicing isoforms for TARSL2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TARSL2 expression in normal human tissues (normalized intensities)      TARSL2 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCTCAGCTG
    TARSL2 Expression
    About this image


    TARSL2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Brain (Nervous System)    fully expand to see all 7 entries
             Thalamus
             brain/midbrain   
     
     Nose (Sensory Organs)    fully expand to see all 2 entries
             sensory organ/nose/nasal cavity   
     
     Neural Tube (Nervous System)    fully expand to see all 2 entries
             Telencephalon
     
     Ovary (Reproductive System)
             XX Germ Cells Ovigerous Cord
     
     Gonad
             XX Germ Cells Ovigerous Cord

    See TARSL2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TARSL2

    SOURCE GeneReport for Unigene cluster: Hs.657163
        SABiosciences Custom PCR Arrays for TARSL2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TARSL2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for TARSL2 gene from 10/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tarsl21 , 5 threonyl-tRNA synthetase-like 21, 5 85.19(n)1
    86.84(a)1
      7 (35.23 cM)5
    2723961  NM_172310.21  NP_758514.21 
     656448985 
    chicken
    (Gallus gallus)
    Aves TARSL21 threonyl-tRNA synthetase-like 2 75.62(n)
    76.85(a)
      415389  XM_413774.3  XP_413774.3 
    lizard
    (Anolis carolinensis)
    Reptilia TARSL26
    Uncharacterized protein
    68(a)
    1 ↔ 1
    GL343644.1(17703-28093)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.180832 Xenopus laevis transcribed sequence with weak similarity more 78.81(n)    CF287106.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tarsl26
    TARSL2 (2 of 2)6
    threonyl-tRNA synthetase-like 2
    71(a)
    59(a)
    1 ↔ many
    1 ↔ many
    18(324173-329033)
    16(1249544-1263364)
    fruit fly
    (Drosophila melanogaster)
    Insecta Aats-thr6
    Threonyl-tRNA synthetase
    62(a)
    possible ortholog
    2L(12103734-12106894)
    worm
    (Caenorhabditis elegans)
    Secernentea tars-16
    Threonine--tRNA ligase, cytoplasmic
    56(a)
    possible ortholog
    II(11691326-11695657)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes THS16
    Threonyl-tRNA synthetase, essential cytoplasmic pr...
    52(a)
    1 → many
    IX(212499-214703)
    soybean
    (Glycine max)
    eudicotyledons Gma.25472 Transcribed sequence with strong similarity to protein more 73.18(n)  
    corn
    (Zea mays)
    Liliopsida Zm.65592 Zea mays PCO073595 mRNA sequence 74.94(n)    AY103693.1 


    ENSEMBL Gene Tree for TARSL2 (if available)
    TreeFam Gene Tree for TARSL2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TARSL2 gene
    TARS22  MRPL392  TARS2  
    3 SIMAP similar genes for TARSL2 using alignment to 3 protein entries:     SYTC2_HUMAN (see all proteins):
    TARS    DKFZp667F1511    TARS2

    TARSL2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1542 SNPs in TARSL2 are shown (see all 1542)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1413559231,2
    --102194602(+) TCCCCC/TGTGGA 1 -- ut310--------
    rs1870697651,2
    --102194648(+) CGTTCA/GTCGTC 1 -- ut310--------
    rs2010768921,2
    --102194772(+) AAATAC/TCAGGG 1 -- ut310--------
    rs1167901141,2
    C,F--102194803(+) TCAGCA/GTTGAG 2 N syn12Minor allele frequency- G:0.00WA NA 4666
    rs1929487391,2
    C--102194813(+) GTGTCC/TGTGTC 2 Q R mis10--------
    rs2005436281,2
    C--102194896(+) CGCACA/GTTTAC 2 N syn10--------
    rs1832893951,2
    C--102194962(+) ATGTAT/ATTTAA 1 -- int11Minor allele frequency- A:0.00EU 1173
    rs3695854901,2
    C--102194976(+) AGCAAC/TTTACC 1 -- int10--------
    rs6260731,2
    C,F,A,H--102195035(-) TAATAT/GTAGTG 1 -- int120Minor allele frequency- G:0.16EA NS NA CSA WA 3834
    rs1151989621,2
    C,F--102195177(+) GGGGGG/AAGCTC 1 -- int11Minor allele frequency- A:0.01WA 118

    HapMap Linkage Disequilibrium report for TARSL2 (102193801 - 102264807 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/20 variations for TARSL2 (see all 20):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1418059CNV Deletion17803354
    esv1005771CNV Deletion20482838
    esv3057CNV Deletion18987735
    esv2660030CNV Deletion23128226
    esv2667525CNV Deletion23128226
    nsv1693CNV Insertion18451855
    esv29627CNV Loss19812545
    nsv523315CNV Gain19592680
    nsv528761CNV Gain19592680
    dgv2452n71CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for TARSL2:    About MalaCards
    pneumonia    tuberculosis


    TARSL2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TARSL2
    Human Genome Epidemiology (HuGE) Navigator: TARSL2 (1 document)

    Export disorders for TARSL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TARSL2 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TARSL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    4. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    5. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 123283 HGNC: 24728 AceView: FLJ25005 Ensembl:ENSG00000185418 euGenes: HUgn123283
    ECgene: TARSL2 Kegg: 123283 H-InvDB: TARSL2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TARSL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TARSL2 gene:
    Search GeneIP for patents involving TARSL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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