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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TARS2 Gene

protein-coding   GIFtS: 58
GCID: GC01P150459

Threonyl-TRNA Synthetase 2, Mitochondrial (Putative)

(Previous name: threonyl-tRNA synthetase-like 1)
(Previous symbol: TARSL1)
Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Threonyl-TRNA Synthetase 2, Mitochondrial (Putative)1 2     Threonine TRNA Ligase 21
Threonyl-TRNA Synthetase-Like 11 2 3     thrRS2
TARSL11 2 3     Threonine--TRNA Ligase, Mitochondrial2
EC 6.1.1.33 8     ThrRS3
mitochondrial1     Threonyl-TRNA Synthetase3

External Ids:    HGNC: 307401   Entrez Gene: 802222   Ensembl: ENSG000001433747   OMIM: 6128055   UniProtKB: Q9BW923   

Export aliases for TARS2 gene to outside databases

Previous GC identifers: GC01P148727 GC01P121838


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TARS2 Gene:
This gene encodes a member of the class-II aminoacyl-tRNA synthetase family. The encoded protein is a
mitochondrial aminoacyl-tRNA synthetase. Alternative splicing results in multiple transcript variants. A related
pseudogene has been identified on chromosome 4. (provided by RefSeq, Dec 2012)

GeneCards Summary for TARS2 Gene: 
TARS2 (threonyl-tRNA synthetase 2, mitochondrial (putative)) is a protein-coding gene. Diseases associated with TARS2 include myositis, and pneumonia, and among its related super-pathways are Cytosolic tRNA aminoacylation and Generic Transcription Pathway. GO annotations related to this gene include molecular_function and threonine-tRNA ligase activity. An important paralog of this gene is TARSL2.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NC_018912.2  NT_004487.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TARS2 gene promoter:
         SRF   Elk-1   C/EBPbeta   GATA-3   Pbx1a   Pax-6   SRF (504 AA)   HNF-3beta   Gfi-1   Zic3   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTARS2 promoter sequence
   Search SABiosciences Chromatin IP Primers for TARS2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TARS2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21.2

TARS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TARS2 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P150459:  view genomic region     (about GC identifiers)

Start:
150,459,887 bp from pter      End:
150,480,078 bp from pter
Size:
20,192 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: SYTM_HUMAN, Q9BW92 (See protein sequence)
Recommended Name: Threonine--tRNA ligase, mitochondrial precursor  
Size: 718 amino acids; 81036 Da
Subcellular location: Mitochondrion matrix (By similarity)
Secondary accessions: Q53GW7 Q96I50

Explore the universe of human proteins at neXtProt for TARS2: NX_Q9BW92

Explore proteomics data for TARS2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BW92

  • 4/11 DME Specific Peptides for TARS2 (Q9BW92) (see all 11)
     TIQLDFQ  WEQSGHW  QDDAHIF  DDAHIFC 

    TARS2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TARS2 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001258824.1  NP_001258825.1  NP_079426.2  

    ENSEMBL proteins: 
     ENSP00000358050   ENSP00000358060   ENSP00000475847   ENSP00000358047   ENSP00000475551  
     ENSP00000415002  
    Reactome Protein details: Q9BW92
    Human Recombinant Protein Products for TARS2: 
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    Cloud-Clone Corp. Proteins for TARS2 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005737cytoplasm ----
    GO:0005739mitochondrion ----
    GO:0005759mitochondrial matrix IEA--

    TARS2 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for TARS2


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    aaRS2: Aminoacyl tRNA synthetases / Class II

    5/9 InterPro protein domains (see all 9):
     IPR018163 Thr/Ala-tRNA-synth_IIc_edit
     IPR002314 aa-tRNA-synt_IIb_cons-dom
     IPR002320 Thr-tRNA-ligase_IIa
     IPR012675 Beta-grasp_dom
     IPR006195 aa-tRNA-synth_II

    Graphical View of Domain Structure for InterPro Entry Q9BW92

    ProtoNet protein and cluster: Q9BW92

    3 Blocks protein domains:
    IPB002320 Threonyl-tRNA synthetase signature
    IPB004095 TGS domain
    IPB004154 Anticodon binding domain


    UniProtKB/Swiss-Prot: SYTM_HUMAN, Q9BW92
    Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family


    TARS2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SYTM_HUMAN, Q9BW92
    Catalytic activity: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr)

         Enzyme Number (IUBMB): EC 6.1.1.31 2

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0003674molecular_function ND--
    GO:0004812aminoacyl-tRNA ligase activity ----
    GO:0004829threonine-tRNA ligase activity IEA--
    GO:0005524ATP binding IEA--
         
    TARS2 for ontologies           About GeneDecksing


    Animal Models:
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    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TARS2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1tRNA Aminoacylation
    tRNA Aminoacylation0.57
    Mitochondrial tRNA aminoacylation0.50
    Aminoacyl-tRNA biosynthesis0.54
    2Generic Transcription Pathway
    Gene Expression0.47

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for TARS2
        tRNA Aminoacylation
    Gene Expression
    Mitochondrial tRNA aminoacylation


    1         Kegg Pathway  (Kegg details for TARS2):
        Aminoacyl-tRNA biosynthesis


    TARS2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TARS2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/256 Interacting proteins for TARS2 (Q9BW922, 3 ENSP000003580604) via UniProtKB, MINT, STRING, and/or I2D (see all 256)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ICT1Q141972, 3, ENSP000003015854MINT-8079030 I2D: score=1 STRING: ENSP00000301585
    EIF4A2Q142403, ENSP000003263814I2D: score=1 STRING: ENSP00000326381
    HSPD1P108092, ENSP000003400194MINT-8079030 STRING: ENSP00000340019
    ATG4CQ96DT63I2D: score=1 
    CAMKK2Q96RR43I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006418tRNA aminoacylation for protein translation TAS--
    GO:0006435threonyl-tRNA aminoacylation ----
    GO:0010467gene expression TAS--
    GO:0043039tRNA aminoacylation ----
    GO:0070159mitochondrial threonyl-tRNA aminoacylation TAS15779907

    TARS2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TARS2 (SYTM)

    5 HMDB Compounds for TARS2    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    L-Threonine(2S,3R)-(-)-Threonine (see all 21)72-19-5--
    Phosphoric acidacide phosphorique (FRENCH) (see all 20)7664-38-2--
    Pyrophosphate(4-)Diphosphoric acid ion (see all 10)14000-31-8--

    1 DrugBank Compound for TARS2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    L-Threonine(S)-Threonine (see all 6)72-19-5target--17644600

    Search CenterWatch for drugs/clinical trials and news about TARS2 / SYTM

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TARS2 gene (3 alternative transcripts): 
    NM_001271895.1  NM_001271896.1  NM_025150.4  

    Unigene Cluster for TARS2:

    Threonyl-tRNA synthetase 2, mitochondrial (putative)
    Hs.288974  [show with all ESTs]
    Unigene Representative Sequence: NM_025150
    14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369054 ENST00000369064(uc010pcd.1 uc001euq.3 uc001eur.3 uc009wlt.3 uc009wls.3)
    ENST00000606933 ENST00000369053 ENST00000369051 ENST00000479372 ENST00000467982
    ENST00000466989 ENST00000480070 ENST00000463555 ENST00000460794 ENST00000462578
    ENST00000483046 ENST00000438568
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    1 QIAGEN miScript miRNA Assays for microRNA that regulate TARS2:
    hsa-miR-148b*
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    Inhib. RNA
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    Additional mRNA sequence: 

    AK022590.1 AK222814.1 AK225368.1 AK298773.1 AK315507.1 AL512732.1 AY450558.1 BC000541.2 
    BC007824.2 BC009997.2 NR_073513.1 NR_073514.1 

    11 DOTS entries:

    DT.308463  DT.100784793  DT.100784790  DT.102828443  DT.121447939  DT.121447959  DT.121447964  DT.121447969 
    DT.40308418  DT.40225237  DT.95089088 

    24/165 AceView cDNA sequences (see all 165):

    BM474278 AA353210 BI087779 AA552157 AA653173 BQ230411 BM974316 NM_025150 
    BQ684745 BC009997 BU155618 BU191823 AL520830 CK430228 BU543143 BE730976 
    BX281571 BC000541 BQ303296 BQ940615 BM834367 AL512732 AW627780 BP372834 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for TARS2 (see all 14)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b ^ 7a · 7b · 7c · 7d ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b · 10c ^
    SP1:                                -           -                                         -     -     -                                                         
    SP2:                                -           -                                   -     -     -     -     -     -     -     -     -     -                     
    SP3:                                -           -                                         -     -     -                 -     -                                 
    SP4:                                                                                -     -     -     -                 -     -     -     -                     
    SP5:                                                                                      -     -     -                 -     -     -     -                     

    ExUns: 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b
    SP1:                                                            
    SP2:                                                            
    SP3:                                                            
    SP4:                                                            
    SP5:                                                            


    ECgene alternative splicing isoforms for TARS2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TARS2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGCTCTCC
    TARS2 Expression
    About this image


    See TARS2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TARS2

    SOURCE GeneReport for Unigene cluster: Hs.288974
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for TARS2 gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tars21 , 5 threonyl-tRNA synthetase 2, mitochondrial (putative)1, 5 83.75(n)1
    84.26(a)1
      3 (40.93 cM)5
    718071  NM_027931.31  NP_082207.21 
     957399765 
    chicken
    (Gallus gallus)
    Aves LOC7704071 threonyl-tRNA synthetase, mitochondrial-like 62.61(n)
    60.9(a)
      770407  XM_001233745.2  XP_001233746.2 
    lizard
    (Anolis carolinensis)
    Reptilia TARS26
    Uncharacterized protein
    59(a)
    1 ↔ 1
    GL343802.1(115686-171078)
    zebrafish
    (Danio rerio)
    Actinopterygii TARS26
    threonyl-tRNA synthetase 2, mitochondrial (putativ...
    34(a)
    1 ↔ 1
    16(1211451-1215528)
    fruit fly
    (Drosophila melanogaster)
    Insecta Aats-thr6
    Threonyl-tRNA synthetase
    47(a)
    possible ortholog
    2L(12103734-12106894)
    worm
    (Caenorhabditis elegans)
    Secernentea tars-16
    Threonine--tRNA ligase, cytoplasmic
    46(a)
    possible ortholog
    II(11691326-11695657)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes THS16
    Threonyl-tRNA synthetase, essential cytoplasmic pr...
    44(a)
    1 → many
    IX(212499-214703)


    ENSEMBL Gene Tree for TARS2 (if available)
    TreeFam Gene Tree for TARS2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TARS2 gene
    TARSL22  MRPL392  TARS2  
    3 SIMAP similar genes for TARS2 using alignment to 5 protein entries:     SYTM_HUMAN (see all proteins):
    DKFZp667F1511    TARS    TARSL2

    TARS2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TARS2
    PGOHUM00000245702


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/518 SNPs in TARS2 are shown (see all 518)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1469297441,2
    --121836013(+) TCATAC/GTTTAC 5 -- us2k10--------
    rs1378559621,2
    --121836016(+) TACTTC/TACTAC 5 -- us2k10--------
    rs38205441,2
    C,F,A--150457876(-) CTTTAT/ACCTTT 5 -- us2k1 trp36Minor allele frequency- A:0.30NA EA 384
    rs1434258691,2
    C--150457992(+) TGGGAA/GCAAAC 5 -- us2k10--------
    rs49709641,2
    C,F,A,H--150458029(+) AAAGAA/GAACCA 5 -- us2k117Minor allele frequency- N:0.00EA NA NS WA CSA 1001
    rs49709221,2
    C,F,A,H--150458094(+) TCTGTA/CAGATT 5 -- us2k121Minor allele frequency- C:0.47NS EA WA NA CSA 2345
    rs1923958031,2
    --150458285(+) CTACTC/TGGGAG 5 -- us2k10--------
    rs1468946501,2
    C--150458335(+) GTTGCC/GGTAAG 5 -- us2k10--------
    rs1389550711,2
    --150458482(+) AGATTA/CTTGAT 5 -- us2k10--------
    rs1839154521,2
    --150458567(+) ATCTCA/GGCTCA 5 -- us2k10--------

    HapMap Linkage Disequilibrium report for TARS2 (150459887 - 150480078 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TARS2: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TARS2
    DNA2.0 Custom Variant and Variant Library Synthesis for TARS2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612805    OMIM disorders: --

    4 diseases for TARS2:    About MalaCards
    myositis    pneumonia    diabetes mellitus    tuberculosis

    1 disease from the University of Copenhagen DISEASES database for TARS2:
    Myositis

    TARS2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TARS2
    Human Genome Epidemiology (HuGE) Navigator: TARS2 (2 documents)

    Export disorders for TARS2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TARS2 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with TARS2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    2. Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study. (PubMed id 19209188)1, 4 Reiling E....Dekker J.M. (2009)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. (PubMed id 15779907)1, 2 Bonnefond L....Sissler M. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    10. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80222 HGNC: 30740 AceView: FLJ12528 Ensembl:ENSG00000143374 euGenes: HUgn80222
    ECgene: TARS2 Kegg: 80222 H-InvDB: TARS2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TARS2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TARS2 gene:
    Search GeneIP for patents involving TARS2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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