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Aliases for TARP Gene

Aliases for TARP Gene

  • TCR Gamma Alternate Reading Frame Protein 3
  • T-Cell Receptor Gamma-Chain Constant Region 3
  • T Cell Receptor Gamma Chain Variable 3
  • TCR V Gamma 3J<Gamma>2C<Gamma>2 3
  • Antigen, T-Cell Receptor 3
  • TCR V3-JP2-Cgamma2 3
  • Vgamma9ChainTCRMOP 3
  • TCR- Gamma V-IV 3
  • TCRGC1 3
  • TCRGC2 3
  • TCRGV 3
  • CD3G 3
  • TCRG 3

External Ids for TARP Gene

Previous GeneCards Identifiers for TARP Gene

  • GC07U901521
  • GC07M038055
  • GC07M038265
  • GC07M038299
  • GC07M038183
  • GC07M038308

Summaries for TARP Gene

Entrez Gene Summary for TARP Gene

  • In some non-lymphoid tissues, the unrearranged T cell receptor gamma (TRG@) locus is expressed. The resulting transcript contains a subset of the TRG@ gene segments and is shorter than TRG@ transcripts expressed in lymphoid tissues. This RefSeq record represents the unrearranged TRG@ locus transcript; the complete TRG@ locus is represented by the genomic RefSeq NG_001336. The transcript represented by this RefSeq has two open reading frames (ORFs) that encode different proteins. The downstream ORF is in the same frame as TRG@ and its protein product is similar to TRG@ proteins. The upstream ORF uses a different reading frame and encodes a novel protein. [provided by RefSeq, Jul 2008]

GeneCards Summary for TARP Gene

TARP (TCR Gamma Alternate Reading Frame Protein) is a Protein Coding gene.

Gene Wiki entry for TARP Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TARP Gene

Genomics for TARP Gene

Regulatory Elements for TARP Gene

Enhancers for TARP Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G038307 1.5 FANTOM5 ENCODE dbSUPER 4.8 -4.2 -4172 4.4 HDGF ATF1 CREB3L1 YY1 GLIS2 ZNF143 KDM4B ZNF263 SP3 ZNF592 TRGV9 STARD3NL TRGV5 TARP LOC103689914
GH07G038231 1.7 FANTOM5 Ensembl ENCODE dbSUPER 2.8 +71.9 71885 4.8 BCOR CTCF WRNIP1 BACH1 ZMYM3 MAX GATA3 ADNP RELB IKZF2 TRGC2 STARD3NL TARP
GH07G038329 1.7 FANTOM5 Ensembl ENCODE dbSUPER 2.3 -25.4 -25430 2.6 HDAC1 YBX1 RAD21 ZNF143 IKZF2 CREM CAVIN1 JUNB ELF4 ELF1 ENSG00000272908 STARD3NL TRGV5P TARP TRGV8 TRGV7
GH07G038394 0.8 FANTOM5 Ensembl 2.9 -89.3 -89292 1.1 CTCF PBX2 RAD21 AMPH TRGV5 STARD3NL TARP TRGV1 RN7SL83P
GH07G038280 0.6 FANTOM5 dbSUPER 2.7 +24.6 24637 0.4 TRGC2 TARP GC07P038279 TRGV11
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TARP on UCSC Golden Path with GeneCards custom track

Genomic Location for TARP Gene

Chromosome:
7
Start:
38,257,879 bp from pter
End:
38,305,646 bp from pter
Size:
47,768 bases
Orientation:
Minus strand

Genomic View for TARP Gene

Genes around TARP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TARP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TARP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TARP Gene

Proteins for TARP Gene

  • Protein details for TARP Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Q0VGM3
    Recommended name:
    TARP protein
    Protein Accession:
    Q0VGM3

    Protein attributes for TARP Gene

    Size:
    111 amino acids
    Molecular mass:
    12847 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TARP Gene

Post-translational modifications for TARP Gene

No Post-translational modifications

No data available for DME Specific Peptides for TARP Gene

Domains & Families for TARP Gene

Protein Domains for TARP Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TARP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TARP: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TARP Gene

Function for TARP Gene

genes like me logo Genes that share phenotypes with TARP: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TARP Gene

Localization for TARP Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TARP Gene

Pathways & Interactions for TARP Gene

No Data Available

Interacting Proteins for TARP Gene

Gene Ontology (GO) - Biological Process for TARP Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TARP Gene

Drugs & Compounds for TARP Gene

(7) Drugs for TARP Gene - From: ClinicalTrials

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Anti-Infective Agents Pharma 22062
Antiviral Agents Pharma 9967
Interferon Inducers Pharma 294
interferons Pharma 2175
Poly I-C Pharma 71
genes like me logo Genes that share compounds with TARP: view

Transcripts for TARP Gene

mRNA/cDNA for TARP Gene

Unigene Clusters for TARP Gene

TCR gamma alternate reading frame protein:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TARP Gene

No ASD Table

Relevant External Links for TARP Gene

GeneLoc Exon Structure for
TARP

Expression for TARP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TARP Gene

SOURCE GeneReport for Unigene cluster for TARP Gene:

Hs.534032
genes like me logo Genes that share expression patterns with TARP: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TARP Gene

Orthologs for TARP Gene

This gene was present in the common ancestor of chordates.

Orthologs for TARP Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TARP 34
  • 73.97 (n)
dog
(Canis familiaris)
Mammalia TARP 34
  • 69.67 (n)
chicken
(Gallus gallus)
Aves TARP 34
  • 45.28 (n)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101731421 34
Species where no ortholog for TARP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

No data available for Evolution for TARP Gene

Paralogs for TARP Gene

(2) SIMAP similar genes for TARP Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TARP: view

No data available for Paralogs for TARP Gene

Variants for TARP Gene

Sequence variations from dbSNP and Humsavar for TARP Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000029142 -- 38,247,714(+) GTCTC(C/T)TGTAT intron-variant
rs1000071284 -- 38,274,336(+) AGCAG(A/G)AGAAT intron-variant, upstream-variant-2KB
rs1000086703 -- 38,244,836(+) GGAGG(C/T)TGTAG intron-variant
rs1000195717 -- 38,250,490(+) CCACC(A/G)TGCCT intron-variant
rs1000518653 -- 38,261,002(+) AAATG(A/G)GATGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TARP Gene

Variant ID Type Subtype PubMed ID
dgv1100n67 CNV loss 20364138
dgv11274n54 CNV loss 21841781
dgv11275n54 CNV loss 21841781
dgv1887e212 CNV gain 25503493
dgv1888e212 CNV gain 25503493
dgv1889e212 CNV loss 25503493
dgv1890e212 CNV loss 25503493
dgv1891e212 CNV loss 25503493
dgv1892e212 CNV loss 25503493
dgv6322n100 CNV loss 25217958
dgv6323n100 CNV gain 25217958
dgv6324n100 CNV gain 25217958
dgv6325n100 CNV loss 25217958
dgv6326n100 CNV loss 25217958
dgv6327n100 CNV loss 25217958
dgv6328n100 CNV gain+loss 25217958
dgv6329n100 CNV loss 25217958
dgv89n68 CNV gain 17160897
esv1000823 CNV deletion 20482838
esv2108072 CNV deletion 18987734
esv22812 CNV gain 19812545
esv2534366 CNV deletion 19546169
esv2734276 CNV deletion 23290073
esv2734277 CNV deletion 23290073
esv2734278 CNV deletion 23290073
esv2759524 CNV loss 17122850
esv2764044 CNV gain+loss 21179565
esv29985 CNV loss 17803354
esv33146 CNV gain+loss 17666407
esv34699 CNV loss 17911159
esv3541505 CNV deletion 23714750
esv3571749 CNV loss 25503493
esv3576323 CNV gain 25503493
esv3576324 CNV gain 25503493
esv3576331 CNV gain 25503493
esv3612869 CNV loss 21293372
esv3612870 CNV gain 21293372
esv6973 CNV loss 19470904
nsv1025142 CNV loss 25217958
nsv1126779 CNV deletion 24896259
nsv436906 CNV insertion 17901297
nsv464431 CNV loss 19166990
nsv511960 CNV loss 21212237
nsv5705 CNV deletion 18451855
nsv8076 CNV gain 18304495
nsv820039 CNV loss 19587683
nsv824074 CNV loss 20364138
nsv824075 CNV loss 20364138
nsv966779 CNV duplication 23825009

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for TARP Gene

Disorders for TARP Gene

Relevant External Links for TARP

Human Genome Epidemiology (HuGE) Navigator
TARP
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TARP

No disorders were found for TARP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TARP Gene

Publications for TARP Gene

  1. Transmembrane AMPA receptor regulatory protein (TARP) dysregulation in anterior cingulate cortex in schizophrenia. (PMID: 23566497) Drummond J.B. … Meador-Woodruff J.H. (Schizophr. Res. 2013) 3 64
  2. Value of T cell receptor gamma alternate reading frame protein and keratin 5 in endometrial carcinoma. (PMID: 24238509) Zhao L.J. … Wei L.H. (Chin. Med. J. 2013) 3 64
  3. T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2+ prostate and breast cancer cells. (PMID: 23019373) Hillerdal V. … Essand M. (Proc. Natl. Acad. Sci. U.S.A. 2012) 3 64
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64
  5. Diagnostic and prognostic value of T-cell receptor gamma alternative reading frame protein (TARP) expression in prostate cancer. (PMID: 20376779) Fritzsche F.R. … Kristiansen G. (Histol. Histopathol. 2010) 3 64

Products for TARP Gene

Sources for TARP Gene

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