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Aliases for TARP Gene

Aliases for TARP Gene

  • TCR Gamma Alternate Reading Frame Protein 3
  • T-Cell Receptor Gamma-Chain Constant Region 3
  • Vgamma9ChainTCRMOP 3
  • TCR- Gamma V-IV 3
  • TCRGC1 3
  • TCRGC2 3
  • TCRGV 3
  • CD3G 3
  • TCRG 3

External Ids for TARP Gene

Previous GeneCards Identifiers for TARP Gene

  • GC07U901521
  • GC07M038055
  • GC07M038265
  • GC07M038299
  • GC07M038183
  • GC07M038308

Summaries for TARP Gene

Entrez Gene Summary for TARP Gene

  • In some non-lymphoid tissues, the unrearranged T cell receptor gamma (TRG@) locus is expressed. The resulting transcript contains a subset of the TRG@ gene segments and is shorter than TRG@ transcripts expressed in lymphoid tissues. This RefSeq record represents the unrearranged TRG@ locus transcript; the complete TRG@ locus is represented by the genomic RefSeq NG_001336. The transcript represented by this RefSeq has two open reading frames (ORFs) that encode different proteins. The downstream ORF is in the same frame as TRG@ and its protein product is similar to TRG@ proteins. The upstream ORF uses a different reading frame and encodes a novel protein. [provided by RefSeq, Jul 2008]

GeneCards Summary for TARP Gene

TARP (TCR Gamma Alternate Reading Frame Protein) is a Protein Coding gene. Among its related pathways are Immune System and Regulation of actin dynamics for phagocytic cup formation.

Gene Wiki entry for TARP Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TARP Gene

Genomics for TARP Gene

Regulatory Elements for TARP Gene

Promoters for TARP Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TARP on UCSC Golden Path with GeneCards custom track

Genomic Location for TARP Gene

Chromosome:
7
Start:
38,257,879 bp from pter
End:
38,305,646 bp from pter
Size:
47,768 bases
Orientation:
Minus strand

Genomic View for TARP Gene

Genes around TARP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TARP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TARP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TARP Gene

Proteins for TARP Gene

  • Protein details for TARP Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Q0VGM3
    Recommended name:
    TARP protein
    Protein Accession:
    Q0VGM3

    Protein attributes for TARP Gene

    Size:
    111 amino acids
    Molecular mass:
    12847 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TARP Gene

Proteomics data for TARP Gene at MOPED

Post-translational modifications for TARP Gene

No Post-translational modifications

Other Protein References for TARP Gene

REFSEQ proteins:

No data available for DME Specific Peptides for TARP Gene

Domains & Families for TARP Gene

Protein Domains for TARP Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TARP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TARP: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TARP Gene

Function for TARP Gene

Phenotypes for TARP Gene

genes like me logo Genes that share phenotypes with TARP: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TARP Gene

Localization for TARP Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TARP Gene

Pathways & Interactions for TARP Gene

genes like me logo Genes that share pathways with TARP: view

Interacting Proteins for TARP Gene

Gene Ontology (GO) - Biological Process for TARP Gene

None

No data available for SIGNOR curated interactions for TARP Gene

Drugs & Compounds for TARP Gene

(7) Drugs for TARP Gene - From: ClinicalTrials

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Anti-Infective Agents Pharma 17220
Antiviral Agents Pharma 8071
Immunologic Factors Pharma 18483
interferons Pharma 1930
Poly I-C Pharma 22
genes like me logo Genes that share compounds with TARP: view

Transcripts for TARP Gene

mRNA/cDNA for TARP Gene

Unigene Clusters for TARP Gene

TCR gamma alternate reading frame protein:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TARP Gene

No ASD Table

Relevant External Links for TARP Gene

GeneLoc Exon Structure for
TARP

Expression for TARP Gene

mRNA expression in normal human tissues for TARP Gene

SOURCE GeneReport for Unigene cluster for TARP Gene Hs.534032

genes like me logo Genes that share expression patterns with TARP: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TARP Gene

Orthologs for TARP Gene

This gene was present in the common ancestor of chordates.

Orthologs for TARP Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TARP 35
  • 73.97 (n)
  • 61.9 (a)
dog
(Canis familiaris)
Mammalia TARP 35
  • 69.67 (n)
  • 59.46 (a)
chicken
(Gallus gallus)
Aves TARP 35
  • 45.28 (n)
  • 30.19 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101731421 35
Species with no ortholog for TARP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

No data available for Evolution for TARP Gene

Paralogs for TARP Gene

(2) SIMAP similar genes for TARP Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TARP: view

No data available for Paralogs for TARP Gene

Variants for TARP Gene

Sequence variations from dbSNP and Humsavar for TARP Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs887457 -- 38,301,272(+) GTTTC(A/T)CCATG intron-variant
rs1002838 -- 38,290,138(-) AATTC(A/G)CTACG intron-variant
rs1002839 -- 38,289,796(-) GTGCA(G/T)TGGAA intron-variant
rs740821 -- 38,285,840(-) GGATA(C/G)AAGAA intron-variant
rs740822 -- 38,285,931(-) CTTGA(G/T)GAGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TARP Gene

Variant ID Type Subtype PubMed ID
dgv89n68 CNV Gain 17160897
dgv2076e1 CNV Complex 17122850
esv29985 CNV Loss 17803354
esv1000823 CNV Deletion 20482838
nsv464431 CNV Loss 19166990
nsv5705 CNV Loss 18451855
esv2108072 CNV Deletion 18987734
esv2734276 CNV Deletion 23290073
esv22812 CNV Gain 19812545
nsv8076 CNV Gain 18304495
esv33146 CNV Gain+Loss 17666407
nsv887963 CNV Loss 21882294
dgv1100n67 CNV Loss 20364138
nsv820039 CNV Loss 19587683
nsv436906 CNV Insertion 17901297
nsv511960 CNV Loss 21212237
esv6973 CNV Loss 19470904
esv2734277 CNV Deletion 23290073
nsv824074 CNV Loss 20364138
essv20735 CNV CNV 17122850
esv2534366 CNV Deletion 19546169
esv2734278 CNV Deletion 23290073
nsv824075 CNV Loss 20364138
esv34699 CNV Loss 17911159

Relevant External Links for TARP Gene

HapMap Linkage Disequilibrium report
TARP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TARP Gene

Disorders for TARP Gene

Relevant External Links for TARP

Human Genome Epidemiology (HuGE) Navigator
TARP

No disorders were found for TARP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TARP Gene

Publications for TARP Gene

  1. Transmembrane AMPA receptor regulatory protein (TARP) dysregulation in anterior cingulate cortex in schizophrenia. (PMID: 23566497) Drummond J.B. … Meador-Woodruff J.H. (Schizophr. Res. 2013) 3 67
  2. Value of T cell receptor gamma alternate reading frame protein and keratin 5 in endometrial carcinoma. (PMID: 24238509) Zhao L.J. … Wei L.H. (Chin. Med. J. 2013) 3
  3. T cells engineered with a T cell receptor against the prostate antigen TARP specifically kill HLA-A2+ prostate and breast cancer cells. (PMID: 23019373) Hillerdal V. … Essand M. (Proc. Natl. Acad. Sci. U.S.A. 2012) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. Diagnostic and prognostic value of T-cell receptor gamma alternative reading frame protein (TARP) expression in prostate cancer. (PMID: 20376779) Fritzsche F.R. … Kristiansen G. (Histol. Histopathol. 2010) 3

Products for TARP Gene

Sources for TARP Gene

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