Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TARM1 Gene

Aliases for TARM1 Gene

  • T Cell-Interacting, Activating Receptor On Myeloid Cells 1 2 3
  • OSCAR-Like Transcript-2 Protein 3 4
  • OLT-2 3 4
  • T-Cell-Interacting, Activating Receptor On Myeloid Cells Protein 1 3

External Ids for TARM1 Gene

Summaries for TARM1 Gene

GeneCards Summary for TARM1 Gene

TARM1 (T Cell-Interacting, Activating Receptor On Myeloid Cells 1) is a Protein Coding gene. Diseases associated with TARM1 include exanthema subitum. An important paralog of this gene is KIR2DL4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TARM1 Gene

Genomics for TARM1 Gene

Genomic Location for TARM1 Gene

Start:
54,069,895 bp from pter
End:
54,081,365 bp from pter
Size:
11,471 bases
Orientation:
Minus strand

Genomic View for TARM1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TARM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TARM1 Gene

No data available for Regulatory Elements for TARM1 Gene

Proteins for TARM1 Gene

  • Protein details for TARM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B6A8C7-TARM1_HUMAN
    Recommended name:
    T-cell-interacting, activating receptor on myeloid cells protein 1
    Protein Accession:
    B6A8C7
    Secondary Accessions:
    • B4DWY4

    Protein attributes for TARM1 Gene

    Size:
    271 amino acids
    Molecular mass:
    29474 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TARM1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TARM1 Gene

Proteomics data for TARM1 Gene at MOPED

Post-translational modifications for TARM1 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn44

Other Protein References for TARM1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TARM1 Gene

Domains for TARM1 Gene

Gene Families for TARM1 Gene

HGNC:
  • IGD :Immunoglobulin superfamily / Immunoglobulin-like domain containing

Protein Domains for TARM1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

TARM1_HUMAN
Domain:
  • Contains 2 Ig-like C2-type (immunoglobulin-like) domains.:
    • B6A8C7
genes like me logo Genes that share domains with TARM1: view

Function for TARM1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TARM1 Gene

Localization for TARM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TARM1 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TARM1 Gene COMPARTMENTS Subcellular localization image for TARM1 gene
Compartment Confidence
plasma membrane 3
extracellular 2
lysosome 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for TARM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TARM1: view

Pathways for TARM1 Gene

SuperPathways for TARM1 Gene

No Data Available

Interacting Proteins for TARM1 Gene

Gene Ontology (GO) - Biological Process for TARM1 Gene

None

No data available for Pathways by source for TARM1 Gene

Transcripts for TARM1 Gene

mRNA/cDNA for TARM1 Gene

(20) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TARM1 Gene

T cell-interacting, activating receptor on myeloid cells 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TARM1 Gene

No ASD Table

Relevant External Links for TARM1 Gene

GeneLoc Exon Structure for
TARM1
ECgene alternative splicing isoforms for
TARM1

Expression for TARM1 Gene

mRNA expression in normal human tissues for TARM1 Gene

mRNA differential expression in normal tissues according to GTEx for TARM1 Gene

This gene is overexpressed in Whole Blood (47.1).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TARM1 Gene

SOURCE GeneReport for Unigene cluster for TARM1 Gene Hs.694674

genes like me logo Genes that share expressions with TARM1: view

Orthologs for TARM1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TARM1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TARM1 36
  • 99.14 (n)
  • 98.89 (a)
TARM1 37
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TARM1 36
  • 69.05 (n)
  • 57.89 (a)
TARM1 37
  • 53 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 38 (a)
OneToMany
-- 37
  • 56 (a)
OneToMany
LOC484314 36
  • 74.3 (n)
  • 62.98 (a)
mouse
(Mus musculus)
Mammalia Tarm1 36
  • 65.65 (n)
  • 53.61 (a)
Tarm1 16
Tarm1 37
  • 48 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 18 (a)
OneToMany
-- 37
  • 15 (a)
OneToMany
-- 37
  • 38 (a)
OneToMany
-- 37
  • 15 (a)
OneToMany
-- 37
  • 18 (a)
OneToMany
-- 37
  • 18 (a)
OneToMany
-- 37
  • 18 (a)
OneToMany
-- 37
  • 17 (a)
OneToMany
-- 37
  • 22 (a)
OneToMany
-- 37
  • 12 (a)
OneToMany
-- 37
  • 28 (a)
OneToMany
-- 37
  • 23 (a)
OneToMany
-- 37
  • 20 (a)
OneToMany
-- 37
  • 30 (a)
OneToMany
-- 37
  • 32 (a)
OneToMany
-- 37
  • 32 (a)
OneToMany
-- 37
  • 21 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia TARM1 37
  • 23 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tarm1 36
  • 64.95 (n)
  • 53.55 (a)
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 12 (a)
OneToMany
Species with no ortholog for TARM1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TARM1 Gene

ENSEMBL:
Gene Tree for TARM1 (if available)
TreeFam:
Gene Tree for TARM1 (if available)

Paralogs for TARM1 Gene

Selected SIMAP similar genes for TARM1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for TARM1 Gene

genes like me logo Genes that share paralogs with TARM1: view

Variants for TARM1 Gene

Sequence variations from dbSNP and Humsavar for TARM1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs166209 -- 54,082,133(+) caaca(C/T)gccca upstream-variant-2KB
rs254245 -- 54,080,096(-) tcctt(C/T)ctttc intron-variant
rs254246 -- 54,079,280(-) tcttt(C/T)ttttt intron-variant
rs612586 -- 54,080,194(-) cttgc(C/T)tgctt intron-variant
rs680872 -- 54,077,727(+) TTTTC(C/T)TCttt upstream-variant-2KB, intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TARM1 Gene

Variant ID Type Subtype PubMed ID
esv2718812 CNV Deletion 23290073
nsv833877 CNV Loss 17160897
nsv458782 CNV Gain 19166990
nsv510773 CNV Loss 20534489
nsv182 CNV Loss 15895083
nsv2542 CNV Loss 18451855
nsv470157 CNV Loss 18288195
esv2718852 CNV Deletion 23290073
esv29726 CNV Gain 19812545

Relevant External Links for TARM1 Gene

HapMap Linkage Disequilibrium report
TARM1

Disorders for TARM1 Gene

(1) MalaCards Diseases for TARM1 Gene

Search for TARM1 Gene in MalaCards »

(2) University of Copenhagen DISEASES for TARM1 Gene

genes like me logo Genes that share disorders with TARM1: view

No data available for UniProtKB/Swiss-Prot for TARM1 Gene

Publications for TARM1 Gene

  1. Breakpoint characterization of a novel approximately 59 kb genomic deletion on 19q13.42 in autosomal-dominant retinitis pigmentosa with incomplete penetrance. (PMID: 19050727) KAPhn L. … Golovleva I. (Eur. J. Hum. Genet. 2009) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for TARM1 Gene

Sources for TARM1 Gene

Back to Top

Content