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Aliases for TARM1 Gene

Aliases for TARM1 Gene

  • T Cell-Interacting, Activating Receptor On Myeloid Cells 1 2 3 5
  • OSCAR-Like Transcript-2 Protein 3 4
  • OLT-2 3 4
  • T-Cell-Interacting, Activating Receptor On Myeloid Cells Protein 1 3

External Ids for TARM1 Gene

Previous GeneCards Identifiers for TARM1 Gene

  • GC19M059265
  • GC19M054573
  • GC19M050888

Summaries for TARM1 Gene

GeneCards Summary for TARM1 Gene

TARM1 (T Cell-Interacting, Activating Receptor On Myeloid Cells 1) is a Protein Coding gene. Diseases associated with TARM1 include Exanthema Subitum and Retinitis Pigmentosa. An important paralog of this gene is IGSF1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TARM1 Gene

Genomics for TARM1 Gene

Regulatory Elements for TARM1 Gene

Enhancers for TARM1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around TARM1 on UCSC Golden Path with GeneCards custom track

Genomic Location for TARM1 Gene

54,069,487 bp from pter
54,081,365 bp from pter
11,879 bases
Minus strand

Genomic View for TARM1 Gene

Genes around TARM1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TARM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TARM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TARM1 Gene

Proteins for TARM1 Gene

  • Protein details for TARM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    T-cell-interacting, activating receptor on myeloid cells protein 1
    Protein Accession:
    Secondary Accessions:
    • B4DWY4

    Protein attributes for TARM1 Gene

    271 amino acids
    Molecular mass:
    29474 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TARM1 Gene


neXtProt entry for TARM1 Gene

Post-translational modifications for TARM1 Gene

  • Glycosylation at Asn 44
  • Modification sites at PhosphoSitePlus

Other Protein References for TARM1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TARM1 Gene

Domains & Families for TARM1 Gene

Gene Families for TARM1 Gene

Protein Domains for TARM1 Gene


Suggested Antigen Peptide Sequences for TARM1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
  • Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
genes like me logo Genes that share domains with TARM1: view

Function for TARM1 Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TARM1 Gene

Localization for TARM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TARM1 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

Jensen Localization Image for TARM1 Gene COMPARTMENTS Subcellular localization image for TARM1 gene
Compartment Confidence
plasma membrane 3
extracellular 2
lysosome 1
peroxisome 1
vacuole 1

Gene Ontology (GO) - Cellular Components for TARM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TARM1: view

Pathways & Interactions for TARM1 Gene

SuperPathways for TARM1 Gene

No Data Available

Interacting Proteins for TARM1 Gene

Gene Ontology (GO) - Biological Process for TARM1 Gene


No data available for Pathways by source and SIGNOR curated interactions for TARM1 Gene

Drugs & Compounds for TARM1 Gene

No Compound Related Data Available

Transcripts for TARM1 Gene

mRNA/cDNA for TARM1 Gene

(3) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TARM1 Gene

T cell-interacting, activating receptor on myeloid cells 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TARM1 Gene

No ASD Table

Relevant External Links for TARM1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TARM1 Gene

mRNA expression in normal human tissues for TARM1 Gene

mRNA differential expression in normal tissues according to GTEx for TARM1 Gene

This gene is overexpressed in Whole Blood (x47.1).

Protein differential expression in normal tissues from HIPED for TARM1 Gene

This gene is overexpressed in Fetal gut (35.5) and Kidney (33.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TARM1 Gene

Protein tissue co-expression partners for TARM1 Gene

NURSA nuclear receptor signaling pathways regulating expression of TARM1 Gene:


SOURCE GeneReport for Unigene cluster for TARM1 Gene:

genes like me logo Genes that share expression patterns with TARM1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TARM1 Gene

Orthologs for TARM1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TARM1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TARM1 34
  • 69.05 (n)
  • 57.89 (a)
TARM1 35
  • 53 (a)
(Canis familiaris)
Mammalia LOC484314 34
  • 74.3 (n)
  • 62.98 (a)
-- 35
  • 38 (a)
-- 35
  • 56 (a)
(Mus musculus)
Mammalia Tarm1 34
  • 65.65 (n)
  • 53.61 (a)
Tarm1 16
Tarm1 35
  • 48 (a)
(Pan troglodytes)
Mammalia TARM1 34
  • 99.14 (n)
  • 98.89 (a)
TARM1 35
  • 94 (a)
(Rattus norvegicus)
Mammalia Tarm1 34
  • 64.95 (n)
  • 53.55 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 18 (a)
-- 35
  • 15 (a)
-- 35
  • 38 (a)
-- 35
  • 15 (a)
-- 35
  • 18 (a)
-- 35
  • 18 (a)
-- 35
  • 18 (a)
-- 35
  • 17 (a)
-- 35
  • 22 (a)
-- 35
  • 12 (a)
-- 35
  • 28 (a)
-- 35
  • 23 (a)
-- 35
  • 20 (a)
-- 35
  • 30 (a)
-- 35
  • 32 (a)
-- 35
  • 32 (a)
-- 35
  • 21 (a)
(Ornithorhynchus anatinus)
Mammalia TARM1 35
  • 23 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 12 (a)
Species where no ortholog for TARM1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TARM1 Gene

Gene Tree for TARM1 (if available)
Gene Tree for TARM1 (if available)

Paralogs for TARM1 Gene

(3) SIMAP similar genes for TARM1 Gene using alignment to 1 proteins: Pseudogenes for TARM1 Gene

genes like me logo Genes that share paralogs with TARM1: view

Variants for TARM1 Gene

Sequence variations from dbSNP and Humsavar for TARM1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
VAR_063151 -
VAR_063152 -
VAR_063153 -

Structural Variations from Database of Genomic Variants (DGV) for TARM1 Gene

Variant ID Type Subtype PubMed ID
dgv3653n100 CNV gain 25217958
esv2718812 CNV deletion 23290073
esv2718852 CNV deletion 23290073
esv29726 CNV gain 19812545
esv3379140 CNV insertion 20981092
esv3893246 CNV gain 25118596
nsv1056177 CNV gain 25217958
nsv182 CNV deletion 15895083
nsv2542 CNV deletion 18451855
nsv458782 CNV gain 19166990
nsv470157 CNV loss 18288195
nsv510773 CNV deletion 20534489
nsv580110 CNV gain 21841781
nsv833877 CNV loss 17160897

Variation tolerance for TARM1 Gene

Gene Damage Index Score: 4.31; 62.91% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TARM1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TARM1 Gene

Disorders for TARM1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for TARM1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
exanthema subitum
  • roseola infantum
retinitis pigmentosa
  • retinitis pigmentosa 1
- elite association - COSMIC cancer census association via MalaCards
Search TARM1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for TARM1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TARM1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TARM1 Gene

Publications for TARM1 Gene

  1. TARM1 Is a Novel Leukocyte Receptor Complex-Encoded ITAM Receptor That Costimulates Proinflammatory Cytokine Secretion by Macrophages and Neutrophils. (PMID: 26311901) Radjabova V. … Barrow A.D. (J. Immunol. 2015) 3 65
  2. Breakpoint characterization of a novel approximately 59 kb genomic deletion on 19q13.42 in autosomal-dominant retinitis pigmentosa with incomplete penetrance. (PMID: 19050727) KAPhn L. … Golovleva I. (Eur. J. Hum. Genet. 2009) 3 65
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 65
  4. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4 65

Products for TARM1 Gene

Sources for TARM1 Gene

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