TARM1 Gene
protein-coding GIFtS: 34
GCID: GC19M054573
|
|
T cell-interacting, activating receptor on myeloid cells...
| |
Aliases
for TARM1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| T Cell-Interacting, Activating Receptor On Myeloid Cells 11 2 | | OLT-22 3 | | OSCAR-Like Transcript-2 Protein2 3 | | T-Cell-Interacting, Activating Receptor On Myeloid Cells Protein 12 |
Export aliases for TARM1 gene to outside databasesPrevious GC identifers: GC19M059265 GC19M050888 |
Summaries
for TARM1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TARM1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for TARM1
Other transcription factors
Search SABiosciences Chromatin IP Primers for TARM1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TARM1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.42 Ensembl cytogenetic band: 19q13.42 HGNC cytogenetic band: 19q13.42TARM1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M054573: view genomic region
(about GC identifiers)
Start:
|
54,573,201 bp from pter |
End:
|
54,584,634 bp from pter |
Size:
|
11,434 bases |
Orientation:
|
minus strand |
|
Proteins
for TARM1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TARM1_HUMAN, B6A8C7 (See
protein sequence)Recommended Name: T-cell-interacting, activating receptor on myeloid cells protein 1 precursor Size: 271 amino acids; 29474 Da
Subcellular location: Membrane; Single-pass type I membrane protein (Potential)
Secondary accessions: B4DWY4Alternative splicing: 2 isoforms: B6A8C7-1 B6A8C7-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for TARM1: NX_B6A8C7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_B6A8C7
TARM1 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_001129158.1
ENSEMBL proteins: ENSP00000439454 ENSP00000441055
Human Recombinant Protein Products for TARM1:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
TARM1 for ontologies About GeneDecksing
TARM1 Antibody Products:
Assay Products for TARM1: |
Protein
Domains /
Families
for TARM1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TARM1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry B6A8C7ProtoNet protein and cluster: B6A8C7 UniProtKB/Swiss-Prot: TARM1_HUMAN, B6A8C7Similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains |
Function
for TARM1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TARM1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TARM1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TARM1 (NM_001135686) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TARM1 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TARM1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TARM1 |
|
Pathways & Interactions
for TARM1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TARM1
|
Drugs & Compounds
for TARM1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TARM1
Search CenterWatch for drugs/clinical trials and news about TARM1
|
Transcripts
for TARM1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TARM1 gene: NM_001135686.1 Unigene Cluster for TARM1: T cell-interacting, activating receptor on myeloid cells 1 Hs.694674 [show with all ESTs]Unigene Representative Sequence: AK3017302 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000432826(uc010yei.1) ENST00000446034
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TARM1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TARM1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TARM1 (NM_001135686) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TARM1 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TARM1 |
Additional cDNA sequence: AK301730.1 DQ479398.1 1 AceView cDNA sequence: BG461652
GeneLoc Exon Structure
|
Expression
for TARM1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TARM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGAGCTTTCC
About this image
SOURCE GeneReport for Unigene cluster: Hs.694674
SABiosciences Custom PCR Arrays for TARM1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TARM1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TARM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TARM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TARM1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TARM1 |
Orthologs
for TARM1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TARM1 gene from 2/8 species (see all 8) About this table
ENSEMBL Gene Tree for TARM1 (if available)
TreeFam Gene Tree for TARM1 (if available) |
Paralogs
for TARM1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TARM1 gene
- KIR2DL42 LILRB42 LILRB12 LILRA62 IGSF12 LILRA52 KIR3DL12 OSCAR2
- NCR12 LILRA42 ENSG000002177922 KIR3DX12 LILRA32 LILRB52 KIR3DL32 LILRA12
- KIR2DL12 A1BG2 LILRB22 KIR2DL22 LILRA22 KIR3DL22 KIR2DL32 FCAR2
- LILRB32 GP62
3 SIMAP similar genes for TARM1 using alignment to 1 protein entry: TARM1_HUMAN:VSTM1 FCAR LAIR2
TARM1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for TARM1
PGOHUM00000250586
|
Genomic Variants
for TARM1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TARM1 (54573201 - 54584634 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for TARM1
3 CNVs: 67606 35674 0519 | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for TARM1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TARM1 for disorders About GeneDecksing
4  diseases for TARM1: About MalaCardsexanthema subitum retinitis pigmentosa hepatopulmonary syndrome retinitis
2 diseases from the University of Copenhagen DISEASES database for TARM1:Exanthema subitum Hepatopulmonary syndrome Export disorders for TARM1 gene to outside databases
|
Publications
for TARM1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TARM1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TARM1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Breakpoint characterization of a novel approximately 59 kb genomic deletion on 19q13.42 in autosomal-dominant retinitis pigmentosa with incomplete penetrance. (PubMed id 19050727)1 KAPhn L....Golovleva I. (2009)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)2 Grimwood J.... Lucas S.M. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
|
External Searches for TARM1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TARM1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TARM1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TARM1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TARM1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TARM1 gene:
Search GeneIP for patents involving TARM1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TARM1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TARM1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TARM1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TARM1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TARM1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TARM1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TARM1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TARM1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TARM1 | | OriGene Custom Protein Services for TARM1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TARM1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TARM1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TARM1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TARM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TARM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TARM1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for TARM1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | TARM1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TARM1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for TARM1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TARM1 |
| |  | |
|
|
|
