TARBP1 Gene
protein-coding GIFtS: 56
GCID: GC01M234527
|
|
TAR (HIV-1) RNA binding protein 1(Previous name: Tar (HIV-1) RNA binding protein 1 )
| |
Aliases for TARBP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| TAR (HIV-1) RNA Binding Protein 11 2 | | Probable Methyltransferase TARBP12 | | TRM31 2 3 | | TAR (HIV) RNA Binding Protein 12 | | TRP-1851 2 3 | | TAR (HIV) RNA-Binding Protein 12 | | TRP1852 3 5 | | TAR RNA Loop Binding Protein2 | | TAR RNA-Binding Protein 12 3 | | TRNA Methyltransferase 3 Homolog2 | | TAR RNA-Binding Protein Of 185 KDa2 3 | | EC 2.1.1.-3 |
Export aliases for TARBP1 gene to outside databasesPrevious GC identifers: GC01M232786 GC01M230099 GC01M230902 GC01M231611 GC01M230833 GC01M232593 GC01M205020 |
Summaries for TARBP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for TARBP1: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces achromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivatorTat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. Thiselement forms a stable stem-loop structure and can be bound by either the protein encoded by this gene or by RNApolymerase II. This protein may act to disengage RNA polymerase II from TAR during transcriptional elongation.Alternatively spliced transcripts of this gene may exist, but their full-length natures have not been determined.(provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: TARB1_HUMAN, Q13395Function: Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. Incase of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Bindingof TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone orin conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNA Gene Wiki entry for TARBP1
|
Genomic Views for TARBP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_167186.1
Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for TARBP1 Other transcription factors
Search SABiosciences Chromatin IP Primers for TARBP1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TARBP1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q42.3 Ensembl cytogenetic band: 1q42.2 HGNC cytogenetic band: 1q42.2TARBP1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M234527: view genomic region
(about GC identifiers)
Start:
|
234,527,059 bp from pter |
End:
|
234,614,849 bp from pter |
Size:
|
87,791 bases |
Orientation:
|
minus strand |
|
Proteins for TARBP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: TARB1_HUMAN, Q13395 (See
protein sequence)Recommended Name: Probable methyltransferase TARBP1 Size: 1621 amino acids; 181675 Da
Subunit: Monomer and homodimer
1 PDB 3D structure from and Proteopedia for TARBP1:2HA8 (3D)
 
Secondary accessions: Q9H581Explore the universe of human proteins at neXtProt for TARBP1: NX_Q13395
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13395 TARBP1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_005637.3 ENSEMBL proteins: ENSP00000040877 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table
TARBP1 for ontologies About GeneDecksing
TARBP1 Antibody Products: Assay Products for TARBP1: |
Protein
Domains / Families for TARBP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TARBP1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q13395ProtoNet protein and cluster: Q13395 1 Blocks protein family: IPB001537 tRNA/rRNA methyltransferase (SpoU)
UniProtKB/Swiss-Prot: TARB1_HUMAN, Q13395Similarity: Belongs to the RNA methyltransferase TrmH family |
Function for TARBP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: TARB1_HUMAN, Q13395Function: Probable S-adenosyl-L-methionine-dependent methyltransferase which methylates RNA molecules such as tRNAs. Incase of infection by HIV-1, it binds to the loop region of TAR RNA, a region also bound by RNA polymerase II. Bindingof TARBP1 and RNA polymerase II to HIV-1 TAR RNA is mutually exclusive, suggesting that TARBP1 may function alone orin conjunction with HIV-1 Tat to disengage RNA polymerase II from HIV-1 TAR RNA. May act by methylating HIV-1 TAR RNAEnzyme Number (IUBMB): EC 2.1.1.-1
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TARBP1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TARBP1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TARBP1 (NM_005646) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TARBP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TARBP1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TARBP1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003723 | RNA binding |
IEA | -- | | GO:0008173 | RNA methyltransferase activity |
IEA | -- |
TARBP1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for TARBP1:
|
Pathways & Interactions for TARBP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TARBP1
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
 3 Interacting proteins for TARBP1 (Q133953 ENSP000000408774) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006357 | regulation of transcription from RNA polymerase II promoter |
TAS | 8846792 | | GO:0006396 | RNA processing |
IEA | -- |
TARBP1 for ontologies About GeneDecksing
|
Drugs & Compounds for TARBP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for TARBP1
1 HMDB Compound for TARBP1 About this table Search CenterWatch for drugs/clinical trials and news about TARBP1 / TARB1 
|
Transcripts for TARBP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for TARBP1 gene: NM_005646.3 Unigene Cluster for TARBP1: TAR (HIV-1) RNA binding protein 1 Hs.498115 [show with all ESTs]Unigene Representative Sequence: U388479 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000040877(uc001hwd.3) ENST00000483404 ENST00000462259 ENST00000496673 ENST00000471918 ENST00000484454 ENST00000468077 ENST00000481183 ENST00000463793
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TARBP1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TARBP1 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TARBP1 (NM_005646) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TARBP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TARBP1  |
Additional cDNA sequence: AK055044.1 BC016023.1 U38847.1 11 DOTS entries: DT.455861 DT.92427259 DT.100785828 DT.102822591 DT.121402880 DT.92427256 DT.95082796 DT.101962808 DT.417658 DT.99998840 DT.92030521 24/191 AceView cDNA sequences (see all 191): CB104924 AL699826 AU125388 N75005 F09534 AA128016 BX110268 BX641192 CB133843 CD557271 F11887 AI354872 AI312769 AI623992 BM970587 CD656493 AA367148 AA319787 W05319 BQ434181 AI538671 BM855317 AW151935 BU186332 GeneLoc Exon Structure
5/7 Alternative Splicing Database (ASD) splice patterns (SP) for TARBP1 (see all 7) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23a | · | 23b | · | 23c | ^ | 24 | ^ | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 25a | · | 25b | ^ | 26 | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30a | · | 30b | ^ | 31 | ^ | 32a | · | 32b | ^ | 33a | · | 33b | · | 33c | · | 33d | |
| SP1: | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for TARBP1
|
Expression for TARBP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TARBP1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TGCCTTAAAC
About this image See TARBP1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TARBP1
SOURCE GeneReport for Unigene cluster: Hs.498115 SABiosciences Custom PCR Arrays for TARBP1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TARBP1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TARBP1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TARBP1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TARBP1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TARBP1 |
Orthologs for TARBP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TARBP1 gene from 9/25 species (see all 25) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Gm172961 , 5 |
predicted gene, 172961, 5 |
76.7(n)1 74.79(a)1 |
  |
8 (74.10 cM)5 2127281 NM_001159907.11 NP_001153379.11 1264266525 |
chicken (Gallus gallus) |
Aves |
TARBP11 |
Tar (HIV-1) RNA binding protein 1 |
71.04(n) 68.61(a) |
  |
421517 XM_419559.3 XP_419559.3 |
lizard (Anolis carolinensis) |
Reptilia |
TARBP16 |
-- |
61(a) |
1 ↔ 1 |
1(220109724-220138088) |
African clawed frog (Xenopus laevis) |
Amphibia |
CA793666.12 |
-- |
74.63(n) |
  |
CA793666.1 |
zebrafish (Danio rerio) |
Actinopterygii |
si:dkey-85a20.41 |
si:dkey-85a20.4 |
54.62(n) 49.19(a) |
  |
566303 XM_001921839.3 XP_001921874.3 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG185966 |
-- |
20(a) |
1 ↔ 1 |
3R(18201667-18205681) |
worm (Caenorhabditis elegans) |
Secernentea |
T14B4.13 |
rRNA methylase |
47(a) |
  |
II(6736844-6741332) -- |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT4G176106 |
tRNA/rRNA methyltransferase (SpoU) family protein |
14(a) |
1 ↔ 1 |
4(9805513-9814910) |
rice (Oryza sativa) |
Liliopsida |
AK063593.12 |
-- |
71.61(n) |
  |
AK063593.1 |
ENSEMBL Gene Tree for TARBP1 (if available) TreeFam Gene Tree for TARBP1 (if available)  |
Paralogs for TARBP1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for TARBP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for TARBP1 (234527059 - 234614849 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 3 variations for TARBP1 3 Indels: 71473 42505 24104  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TARBP1 |
|
Disorders
/ Diseases for TARBP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TARBP1 for disorders About GeneDecksing
OMIM gene information: 605052
OMIM disorders: --
6 diseases for TARBP1: About MalaCardsacquired immunodeficiency syndrome immunodeficiency cellulitis vaccinia conjunctivitis malaria
1 Novoseek disease relationship for TARBP1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| immunodeficiency |
56.9 |
4 |
17360756 (2), 8626763 (1), 9230068 (1) |
Human Genome Epidemiology (HuGE) Navigator: TARBP1 (1 document) Export disorders for TARBP1 gene to outside databases
|
Publications for TARBP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TARBP1 gene, integrated from 9 sources (see all 47): (articles sorted by number of sources associating them with TARBP1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Identification of a group of cellular cofactors that stimulate the binding of RNA polymerase II and TRP-185 to human immunodeficiency virus 1 TAR RNA. (PubMed id 8626763)1, 2, 9 Wu-Baer F.... Gaynor R.B. (1996)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- Specific binding of RNA polymerase II to the human immunodeficiency virus trans-activating region RNA is regulated by cellular cofactors and Tat. (PubMed id 7638159)1, 2 Wu-Baer F.... Gaynor R.B. (1995)
- The cellular factor TRP-185 regulates RNA polymerase II binding to HIV-1 TAR RNA. (PubMed id 8846792)1, 2 Wu-Baer F.... Gaynor R.B. (1995)
- tat regulates binding of the human immunodeficiency virus trans-activating region RNA loop-binding protein TRP-185. (PubMed id 1936997)1, 3 Wu F....Gaynor R. (1991)
- Small interfering RNAs against the TAR RNA binding protein, TRBP, a Dicer cofactor, inhibit human immunodeficiency virus type 1 long terminal repeat expression and viral production. (PubMed id 17360756)1, 9 Christensen H.S....Gatignol A. (2007)
- Two distinct nuclear transcription factors recognize loop and bulge residues of the HIV-1 TAR RNA hairpin. (PubMed id 1752441)1, 9 Sheline C.T....Jones K.A. (1991)
- Expression levels of the microRNA maturing microproces sor complex component DGCR8 and the RNA-induced silencing complex (RISC) compone nts argonaute-1, argonaute-2, PACT, TARBP1, and TARBP2 in epithelial skin cancer . (PubMed id 22025453)1 Sand M....Bechara F.G. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for TARBP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing TARBP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TARBP1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TARBP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for TARBP1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TARBP1 gene: Search GeneIP for patents involving TARBP1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for TARBP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for TARBP1 | | OriGene shRNA RFP for TARBP1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TARBP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TARBP1 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for TARBP1 | | OriGene 3'-UTR Clone for TARBP1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TARBP1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TARBP1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for TARBP1 | | OriGene Custom Protein Services for TARBP1 | | OriGene Custom Immunoassay Development | | |
| |  |
 |
| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TARBP1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TARBP1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TARBP1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TARBP1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TARBP1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TARBP1 |
| |
 |  |  |  | |
| | | Search Tocris compounds for TARBP1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | TARBP1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TARBP1 |
|  |  |  | | | ThermoFisher Antibodies for TARBP1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TARBP1 |
|
|
|
|