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TAPBP Gene

protein-coding GIFtS: 62

GC06M033375

TAP binding protein (tapasin)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
NGS-17 ^³
NGS17 ^², ³
TAPA ^¹, ², ³
TPN ^², ³
TPSN ^², ³, ⁵
tapasin ^²

Descriptions
TAP binding protein (tapasin) ^²
TAP-associated protein ^², ³
TAP-binding protein ^³

External Ids
HGNC: 11566¹
Entrez Gene: 6892²
UniProtKB: O15533³

Search outside databases for aliases for TAPBP gene

Previous GC identifers: GC06M033269 GC06M033314

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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EntrezGene summary for TAPBP:

This gene encodes a transmembrane glycoprotein which mediates interaction between newly assembled

major histocompatibility complex (MHC) class I molecules and the transporter associated with

antigen processing (TAP), which is required for the transport of antigenic peptides across the

endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the

MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a

single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to

maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major

histocompatibility complex on chromosome 6. Alternative splicing results in three transcript

variants encoding different isoforms. [provided by RefSeq]

UniProtKB/Swiss-Prot: TPSN_HUMAN, O15533

Function: Involved in the association of MHC class I with transporter associated with antigen

processing (TAP) and in the assembly of MHC class I with peptide (peptide loading)

Gene Wiki entry for TAPBP (Tapasin)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the TAPBP gene

Entrez Gene cytogenetic band: 6p21.3 HGNC cytogenetic band: 6p21.3

TAPBP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M033375: (about GC identifiers)

Start:	33,375,449 bp from pter
End:	33,389,967 bp from pter
Size:	14,519 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000006.10 NT_007592.14 NT_113891.1 NT_113897.1

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: TPSN_HUMAN, O15533 (See protein sequence)

Recommended Name: Tapasin precursor

Size: 448 amino acids; 47626 Da

Subunit: Interacts with TAP1 and is thus a subunit of the TAP complex. Interaction with TAP1 is

TAP2 independent and is required for efficient peptide-TAP interaction. Obligatory mediator for

the interaction between newly assembled MHC class I molecules, clareticulin, ERp57 and TAP. Up to

4 MHC class I/tapasin complexes bind to 1 TAP

Subcellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein

(Probable). Microsome membrane; Single-pass membrane protein (Probable)

Sequence caution: Sequence=AAD32924.2; Type=Frameshift; Positions=Several;

PDB structures from and Proteopedia :

3F8U (3D)

Secondary accessions: A2AB91 A2ABC0 B0V0A6 O15210 O15272 Q5STJ8 Q5STK6 Q5STQ5 Q5STQ6 Q66K65 Q96KK7

Q9HAN8 Q9UEE0 Q9UEE4 Q9UIZ6 Q9Y6K2

Alternative splicing: 3 isoforms: O15533-1 O15533-2 O15533-3

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (3 alternative transcripts):

NP_003181.3 NP_757345.1 NP_757346.1

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (Tapasin)
	Human Recombinant Proteins from Abnova (TAPBP)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

5/7 Gene Ontology (GO) cellular component terms (links to tree view) (see all 7 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000139	Golgi membrane	IDA	11884415
GO:0005783	endoplasmic reticulum	TAS	9238042 9271576
GO:0005789	endoplasmic reticulum membrane	IDA	11884415
GO:0005792	microsome	NAS	11884415
GO:0016020	membrane	IEA	--

About this table

Antibodies for TAPBP:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for TAPBP
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (Tapasin), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Novus Biologicals Antibody for TAPBP

Assays for TAPBP:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry O15533

ProtoNet protein and cluster: O15533

2 Blocks protein families:

IPB003597 Immunoglobulin C-type

IPB008056 Tapasin signature

UniProtKB/Swiss-Prot: TPSN_HUMAN, O15533

Domain: The N-terminus is required for efficient association with MHC class I molecule and for a

stable interaction between MHC I and calreticulin. Binding to TAP is mediated by the C-terminus

region

Similarity: Contains 1 Ig-like C1-type (immunoglobulin-like) domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TAPBP)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TAPBP)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_003190

Applied Biosystems Silencer® siRNAs for TAPBP

Sigma-Aldrich siRNA and siRNA Panels for TAPBP

Sigma-Aldrich shRNA for TAPBP

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for TAPBP
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_003190
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_003190
untagged cDNA clones in CMV expression vector (see all 3): NM_003190

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_003190

UniProtKB/Swiss-Prot: TPSN_HUMAN, O15533

Function: Involved in the association of MHC class I with transporter associated with antigen

processing (TAP) and in the assembly of MHC class I with peptide (peptide loading)

Genatlas biochemistry entry for TAPBP:

tapasin,truncated actin P binding protein,21kDa,widely expressed,involved in the assembly and

function of multimeric MHC class J-TAP complexes,transporter associated with antigen processing

2 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Tapbp):

hematopoietic system

immune system

5/6 Gene Ontology (GO) molecular function terms (links to tree view) (see all 6 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0015433	peptide antigen-transporting ATPase activity	TAS	9238042
GO:0042288	MHC class I protein binding	TAS	12788224
GO:0042605	peptide antigen binding	TAS	12788224
GO:0046978	TAP1 binding	TAS	12788224
GO:0046979	TAP2 binding	TAS	12788224

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for TAPBP (Your Favorite Gene powered by Ingenuity)

Antigen Presentation Pathway

GeneDecks TAPBP for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for TAPBP

3 Interacting proteins for TAPBP (O15533^{1, 2}) via UniProtKB, MINT, and/or STRING
Interactant Interaction Details
GeneCard External ID(s)
TAP1 Q03518¹ EBI-874801, EBI-747259
TAP2 Q03519¹ EBI-874801, EBI-780781
PDIA3 P30101² MINT-4301249
About this table
5 Gene Ontology (GO) biological process terms (links to tree view):
GO ID Qualified GO term Evidence PubMed IDs
GO:0006461 protein complex assembly TAS 9271576
GO:0006890 retrograde vesicle-mediated transport, Golgi to ER NAS 11884415
GO:0006955 immune response TAS 9271576
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I IEA --
GO:0050823 peptide antigen stabilization ISS --
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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for TAPBP
2 Novoseek chemical compound relationships for TAPBP gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
histidine	10.41	6	12517962 (3)
lysine	0.00	10	16751394 (5), 10085102 (1), 15634919 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (TAPBP)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (TAPBP)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_003190

Sigma-Aldrich siRNA and siRNA Panels for TAPBP

Sigma-Aldrich shRNA for TAPBP

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_003190 NM_172208 NM_172209

REFSEQ mRNAs for TAPBP gene (3 alternative transcripts):

NM_003190.3 NM_172208.1 NM_172209.1

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_003190 NM_172208 NM_172209

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_003190
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_003190
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_003190

Additional cDNA sequence:

AB010639.1 AF009510.1 AF029750.1 AF067286.3 AF314222.1 AY007154.1 BC064966.1 BC080574.1

CR591254.1 CR591308.1 CR600344.1 CR614167.1 CR618722.1 EU693375.1 Y13582.1

22 DOTS entries:

DT.91843367 DT.100687058 DT.100687064 DT.449485 DT.95319488 DT.100775691 DT.97821824 DT.97862163

DT.92403120 DT.95128721 DT.121364773 DT.80100178 DT.97862158 DT.91694893 DT.100045302 DT.100763210

DT.121364801 DT.92468618 DT.95105196 DT.97863628 DT.100733389 DT.102833958

24/461 AceView cDNA sequences (see all 461 ):

AI936180 BQ100943 CD366980 AB010639 CR600344 AA595010 BU194614 CR614167

BQ028977 AU131037 BM806505 NM_172209 AF009510 AI623791 BU679276 BQ028976

BF914956 BM747118 BF982266 BQ648536 AY007154 CR591254 AI475624 CR591308

highest scoring ESTs for TAPBP:

AF029750 AB010639 AF009510 AF067286 AF314222 AI989458 AJ714633 AU117273 BE208288 BF792885

Unigene Cluster for TAPBP:

TAP binding protein (tapasin)

Hs.714746 [show with all ESTs]

Unigene Representative Sequence: NM_003190

GeneLoc Exon Structure

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

TAPBP expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for TAPBP

¹ / ² / ³

7 probe-sets matching TAPBP gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
41168_at²^{, 3}	U95-A	3	1.00	0.33	0.82	1.23	AF029750	1.00	1.00	1.00	1
74637_at²^{, 3}	U95-D	3	0.88	0.37	0.89	0.77	AI989458	0.80	1.00	0.91	1
210294_at²^{, 3}	U133-A	3	1.00	0.61	--	--	AF067286	0.80	1.00	0.91	1
208829_at²^{, 3}	U133-A	3	1.00	0.39	--	--	AF029750	1.00	1.00	1.00	1
210294_at²	U133Plus2	3	1.00	0.61	--	--	--	--	--	--	--
208829_at²	U133Plus2	3	1.00	0.39	--	--	--	--	--	--	--
1555565_s_at²	U133Plus2	3	1.00	0.33	--	--	--	--	--	--	--

GeneDecks TAPBP for binary patterns associated with the probe-sets selected above

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GGCTCCTCGA

SOURCE GeneReport for Unigene cluster: Hs.714746
Expression variation in blood from EXPOLDB for TAPBP
UniProtKB/Swiss-Prot: TPSN_HUMAN, O15533
Tissue specificity: Neutrophils, mostly in fully differentiated cells

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for TAPBP gene from 5/7 species (see all 7 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	TAPBP¹	--	TAP binding protein (tapasin)	81.99(n) 80.49(a)	481740 XM_538861.2 XP_538861.2
chimpanzee (Pan troglodytes)	TAPBP¹	--	TAP binding protein (tapasin)	99.48(n) 99.78(a)	746814 XM_001170392.1 XP_001170392.1
cow (Bos taurus)	TAPBP¹	--	TAP binding protein (tapasin)	83.52(n) 82.77(a)	504335 NM_001045885.1 NP_001039350.1
rat (Rattus norvegicus)	Tapbp¹	--	TAP binding protein	78.45(n) 75.84(a)	25217 NM_033098.1 NP_149089.1
mouse (Mus musculus)	Tapbp^{1, 5}	17 (18.41 cM)⁵	TAP binding protein^{1, 5}	78.52(n)¹ 75.17(a)¹	21356¹ NM_001025313.1¹ NP_001020484.1¹ AA407026⁵ AF043943⁵ (see all 33)

About this table Species with no ortholog for TAPBP

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

UniProtKB/Swiss-Prot: TPSN_HUMAN, O15533

Polymorphism: The 2 alleles of TAPBP; TAPBP*01 (Tapasin*01) (shown here) and TAPBP*02 (Tapasin*02);

are in linkage disequilibria with the HLA-DRB1 locus in a Japanese population

10/126 NCBI SNPs in TAPBP are shown (see all 126 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 71)

AB	SNP ID	Valid	Chr 6 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1800838^1,2	A,C,F,H	33380519(-)	`TGGGTT/ACCCTA`	3	--	int¹ ut3¹		8		EU EA WA NA	774
	rs2071888^1,2	A,C,F,H	33380833(-)	`GCCTAC/GAGTTC`	3	T/R	mis¹		16		EA EU WA NS MN	3208
--	rs2071889^1,2	A,C,F	33380690(-)	`TGTGGT/GGACCG`	3	--	int¹ ut3¹		1		MN	96
	rs12664430^1,2	C,F,H	33380655(+)	`AGGCAC/TCCTCT`	3	--	int¹ ut3¹		9		MN EU EA WA	936
	rs1800837^1,2	C,F	33380604(-)	`GAGGGG/ATAATG`	3	--	ut3¹ int¹		1		MN	96
	rs34132052^1,2	F	33379944(+)	`CCTACG/ACTGTC`	3	S/S	syn¹ ut3¹ ng5¹		1		NA	78
--	rs3173275^1,2	C	33379472(-)	`GTCCAA/GTAGAA`	2	--	int¹ ut3¹		0	--	--	--	--
	rs3106191^1,2	A,C,F,H	33388483(-)	`AATCCG/TCAAAG`	3	--	int¹		5		EU EA WA MN	506
	rs3106190^1,2	A,C,F,H	33388607(-)	`AGCAGG/CAGCGT`	3	--	int¹		14		EU EA WA NS MN	1508
	rs2282851^1,2	A,C,F,H	33388287(+)	`ACGTCC/TCAGCC`	3	--	int¹		10		EA EU WA MN	2426

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HapMap Linkage Disequilibrium images for TAPBP (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 601962 disorders: 604571

10/14 Novoseek disease relationships for TAPBP gene (see all 14 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
hla class i deficiency	77.33	3	12149238 (3)
spondylitis ankylosing	45.47	4	17082617 (2), 16385505 (1)
lung carcinoma	24.53	4	11169257 (1), 18316574 (1)
colorectal tumors	18.01	4	15455354 (3), 14750179 (1)
tumors	17.80	45	11169257 (6), 18316574 (3), 15163903 (3), 14519625 (2) (see all 13)
small cell lung cancer	10.87	2	17143611 (1), 16140964 (1)
pancreatic carcinoma	9.30	1	11169257 (1)
melanoma	4.25	9	12682852 (4), 18046553 (1), 18194274 (1)
necrosis	4.02	1	11169257 (1)
colon carcinoma	0.42	1	11169257 (1)

About this table

Human Gene Mutation Database: TAPBP
Genetic Association Database: TAPBP
Human Genome Epidemiology Navigator: TAPBP (6 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/197 PubMed articles for TAPBP gene (see all 197 ):

Cloning and functional characterization of a subunit of the transporter associated with antigen processing. (PubMed id 9238042)^{1, 2, 3, 4} Li S.... Wang P. (1997)
Identification of novel Tapasin polymorphisms and linkage disequilibrium to MHC class I alleles. (PubMed id 11132161)^{1, 3, 6} Williams A.P....Elliott T. (2000)
Tapasin is required for efficient peptide binding to transporter associated with antigen processing. (PubMed id 10636848)^{1, 3, 4} Li S.... Wang P. (2000)
The N-terminal region of tapasin is required to stabilize the MHC class I loading complex. (PubMed id 10382748)^{1, 3, 4} Bangia N.... Cresswell P. (1999)
Generation of a functional, soluble tapasin protein from an alternatively spliced mRNA. (PubMed id 14668790)^{1, 3, 4} Gao B.... Elliott T. (2004)
Granulocyte-macrophage colony-stimulating factor modulates tapasin expression in human neutrophils. (PubMed id 10088603)^{1, 3, 4} El Ouakfaoui S.... Beaulieu A.D. (1999)
A critical role for tapasin in the assembly and function of multimeric MHC class I-TAP complexes. (PubMed id 9271576)^{1, 3, 4} Ortmann B....Cresswell P. (1997)
Polymorphism of TAPASIN and its linkage disequilibria with HLA class II genes in the Japanese population. (PubMed id 9802609)^{1, 3, 4} Furukawa H.... Juji T. (1998)
Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study. (PubMed id 15743475)^{1, 3, 6} Bukulmez H....Colbert R.A. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 6892	HGNC: 11566	AceView: TAPBP	euGenes: HUgn6892	ECgene: TAPBP
H-InvDB: TAPBP

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for TAPBP	Genetics and Cytogenetics in Oncology and Haematology
TAPBPbase	http://bioinf.uta.fi/TAPBPbase/

Licensable Technologies for TAPBP
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for TAPBP:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for TAPBP-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for TAPBP		Antibodies for TAPBP
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for TAPBP		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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TAPBP Gene

protein-coding GIFtS: 62

Aliases &
Descriptions
for TAPBP

Summaries
for TAPBP

Genomic Location
for TAPBP

Proteins
for TAPBP

Protein Domains/
Families
for TAPBP

Gene Function
for TAPBP

Pathways & Interactions
for TAPBP

Drugs & Compounds
for TAPBP

Transcripts
for TAPBP

Expression
for TAPBP

Orthologs
for TAPBP

Paralogs
for TAPBP

SNPs/Variants
for TAPBP

Disorders & Mutations
for TAPBP

Medical News
for TAPBP

Publications
for TAPBP

Search for TAPBP

Genome Databases showing TAPBP

Other Databases showing TAPBP

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for TAPBP

Services
for TAPBP

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

TAPBP Gene

protein-coding GIFtS: 62

Aliases & Descriptionsfor TAPBP

Summariesfor TAPBP

Genomic Locationfor TAPBP

Proteinsfor TAPBP

Protein Domains/Familiesfor TAPBP

Gene Functionfor TAPBP

Pathways & Interactionsfor TAPBP

Drugs & Compoundsfor TAPBP

Transcriptsfor TAPBP

Expression for TAPBP

Orthologsfor TAPBP

Paralogsfor TAPBP

SNPs/Variantsfor TAPBP

Disorders & Mutationsfor TAPBP

Medical Newsfor TAPBP

Publicationsfor TAPBP

Search for TAPBP

Genome Databases showing TAPBP

Other Databases showing TAPBP

Specialized Databases showing TAPBP

Licensable Technologiesfor TAPBP

Servicesfor TAPBP

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for TAPBP

Summaries
for TAPBP

Genomic Location
for TAPBP

Proteins
for TAPBP

Protein Domains/
Families
for TAPBP

Gene Function
for TAPBP

Pathways & Interactions
for TAPBP

Drugs & Compounds
for TAPBP

Transcripts
for TAPBP

Expression
for TAPBP

Orthologs
for TAPBP

Paralogs
for TAPBP

SNPs/Variants
for TAPBP

Disorders & Mutations
for TAPBP

Medical News
for TAPBP

Publications
for TAPBP

Licensable Technologies
for TAPBP

Services
for TAPBP