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Aliases for TAP2 Gene

Aliases for TAP2 Gene

  • Transporter 2, ATP Binding Cassette Subfamily B Member 2 3 5
  • Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) 2 3
  • Peptide Transporter Involved In Antigen Processing 2 3 4
  • Really Interesting New Gene 11 Protein 3 4
  • Peptide Transporter PSF2 3 4
  • Peptide Supply Factor 2 3 4
  • RING11 3 4
  • ABCB3 3 4
  • PSF-2 3 4
  • PSF2 3 4
  • APT2 3 4
  • ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 3 3
  • ATP-Binding Cassette Sub-Family B Member 3 4
  • Transporter 2, ABC (ATP Binding Cassette) 3
  • Antigen Peptide Transporter 2 3
  • Peptide Transporter TAP2 4
  • ABC Transporter, MHC 2 3
  • D6S217E 3
  • ABC18 3
  • Y1 4

External Ids for TAP2 Gene

Previous HGNC Symbols for TAP2 Gene

  • ABCB3

Previous GeneCards Identifiers for TAP2 Gene

  • GC06M032786
  • GC06M032560
  • GC06M032837
  • GC06M032838
  • GC06M032897
  • GC06M032783
  • GC06M032531

Summaries for TAP2 Gene

Entrez Gene Summary for TAP2 Gene

  • The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules. [provided by RefSeq, Feb 2014]

GeneCards Summary for TAP2 Gene

TAP2 (Transporter 2, ATP Binding Cassette Subfamily B Member) is a Protein Coding gene. Diseases associated with TAP2 include Bare Lymphocyte Syndrome, Type I and Herpes Simplex. Among its related pathways are Immune System and Allograft rejection. GO annotations related to this gene include transporter activity and ATPase activity, coupled to transmembrane movement of substances. An important paralog of this gene is ENSG00000250264.

UniProtKB/Swiss-Prot for TAP2 Gene

  • Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. Inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1 and prevents the conformational rearrangement of TAP induced by peptide binding. Inhibited by human adenovirus E3-19K glycoprotein, which binds the TAP complex and acts as a tapasin inhibitor, preventing MHC class I/TAP association.

Gene Wiki entry for TAP2 Gene

No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TAP2 Gene

Genomics for TAP2 Gene

Regulatory Elements for TAP2 Gene

Enhancers for TAP2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH06F032940 1.4 FANTOM5 ENCODE 17 -105.4 -105374 8.8 HDGF ATF1 WRNIP1 SIN3A ARID4B BRCA1 ZNF2 YY1 ZNF143 ZNF207 HLA-DMA BRD2 PSMB9 TAP1 TAP2 HLA-DMB BRD2-IT1 HLA-DPA1 ENSG00000250264 MIR6873
GH06F032982 1.3 Ensembl ENCODE 11.1 -145.4 -145365 2.7 HDGF PKNOX1 ATF1 ARID4B SIN3A FEZF1 ZNF2 SLC30A9 GLIS2 ZNF143 HLA-DMA HLA-DMB ENSG00000250264 TAP2 TAP1 PSMB9 RNY4P10 RXRB SLC39A7 HSD17B8
GH06F032851 1.5 FANTOM5 ENCODE 7.3 -15.1 -15084 5.2 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 PSMB9 TAP1 BRD2 RING1 VPS52 ZBTB12 LEMD2 EHMT2 PSMB8 MIR5004
GH06F032983 0.8 ENCODE 11.1 -143.7 -143736 0.2 KLF1 BMI1 FEZF1 BCL11B POLR2A SCRT2 KLF8 SCRT1 CBFB CEBPB HLA-DMB ENSG00000250264 TAP2 TAP1 PSMB9 RNY4P10 RXRB SLC39A7 HSD17B8 MIR219A1
GH06F033026 1.5 FANTOM5 Ensembl ENCODE 5.7 -190.8 -190819 5.5 HDGF TBP PKNOX1 TBL1XR1 WRNIP1 RAD21 RFX5 ZNF121 ZNF366 EGR1 HLA-DMA HLA-DQB1 HLA-DPA1 HLA-DPB1 HLA-DQB2 HLA-DQA2 HLA-DOA PSMB8 HLA-DMB TAPBP
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TAP2 on UCSC Golden Path with GeneCards custom track

Promoters for TAP2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000025363 323 1401 PKNOX1 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF207 ZNF143

Genomic Location for TAP2 Gene

Chromosome:
6
Start:
32,821,833 bp from pter
End:
32,838,823 bp from pter
Size:
16,991 bases
Orientation:
Minus strand

Genomic View for TAP2 Gene

Genes around TAP2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TAP2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TAP2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for TAP2 Gene

  • Protein details for TAP2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q03519-TAP2_HUMAN
    Recommended name:
    Antigen peptide transporter 2
    Protein Accession:
    Q03519
    Secondary Accessions:
    • B0V2J8
    • O95410
    • Q53FI6
    • Q5HY71
    • Q96PT8
    • Q9UQ83

    Protein attributes for TAP2 Gene

    Size:
    686 amino acids
    Molecular mass:
    75664 Da
    Quaternary structure:
    • Heterodimer of TAP1 and TAP2. Interacts with Epstein-Barr virus BLNF2a. Interacts with herpes simplex virus ICP47 (PubMed:7760936).

    Alternative splice isoforms for TAP2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TAP2 Gene

Post-translational modifications for TAP2 Gene

  • Ubiquitination at Lys 135, Lys 245, and Lys 356
  • Modification sites at PhosphoSitePlus

Other Protein References for TAP2 Gene

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for TAP2 (TAP2)
  • Abcam antibodies for TAP2

No data available for DME Specific Peptides for TAP2 Gene

Domains & Families for TAP2 Gene

Gene Families for TAP2 Gene

Graphical View of Domain Structure for InterPro Entry

Q03519

UniProtKB/Swiss-Prot:

TAP2_HUMAN :
  • The peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2.
  • Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
Domain:
  • The peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2.
  • Contains 1 ABC transmembrane type-1 domain.
  • Contains 1 ABC transporter domain.
Family:
  • Belongs to the ABC transporter superfamily. ABCB family. MHC peptide exporter (TC 3.A.1.209) subfamily.
genes like me logo Genes that share domains with TAP2: view

Function for TAP2 Gene

Molecular function for TAP2 Gene

UniProtKB/Swiss-Prot Function:
Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. Inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1 and prevents the conformational rearrangement of TAP induced by peptide binding. Inhibited by human adenovirus E3-19K glycoprotein, which binds the TAP complex and acts as a tapasin inhibitor, preventing MHC class I/TAP association.
UniProtKB/Swiss-Prot Induction:
By IFNG/IFN-gamma.

Gene Ontology (GO) - Molecular Function for TAP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005215 transporter activity IDA 10835348
GO:0005515 protein binding IPI 12213826
GO:0005524 ATP binding IEA,IMP 15793001
GO:0015197 contributes_to peptide transporter activity IEA,IGI 7673167
GO:0015433 peptide antigen-transporting ATPase activity IMP 1538751
genes like me logo Genes that share ontologies with TAP2: view
genes like me logo Genes that share phenotypes with TAP2: view

Human Phenotype Ontology for TAP2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TAP2 Gene

Localization for TAP2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TAP2 Gene

Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=The transmembrane segments seem to form a pore in the membrane.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TAP2 gene
Compartment Confidence
endoplasmic reticulum 5
nucleus 4
plasma membrane 3
extracellular 2
mitochondrion 1
peroxisome 1
cytosol 1
lysosome 1

Gene Ontology (GO) - Cellular Components for TAP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IEA --
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0016020 membrane IEA,IDA 19946888
GO:0016021 integral component of membrane IEA,IDA 8955196
GO:0030176 integral component of endoplasmic reticulum membrane IEA,IDA 7673167
genes like me logo Genes that share ontologies with TAP2: view

Pathways & Interactions for TAP2 Gene

genes like me logo Genes that share pathways with TAP2: view

Gene Ontology (GO) - Biological Process for TAP2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002250 adaptive immune response IEA --
GO:0002376 immune system process IEA --
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I TAS --
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent IBA --
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent IBA --
genes like me logo Genes that share ontologies with TAP2: view

No data available for SIGNOR curated interactions for TAP2 Gene

Drugs & Compounds for TAP2 Gene

(11) Drugs for TAP2 Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Adenosine triphosphate Approved Nutra 0

(2) Additional Compounds for TAP2 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with TAP2: view

Transcripts for TAP2 Gene

Unigene Clusters for TAP2 Gene

Transporter 2, ATP-binding cassette, sub-family B (MDR/TAP):
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TAP2 Gene

No ASD Table

Relevant External Links for TAP2 Gene

GeneLoc Exon Structure for
TAP2
ECgene alternative splicing isoforms for
TAP2

Expression for TAP2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TAP2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for TAP2 Gene

This gene is overexpressed in Nasal epithelium (30.9) and Peripheral blood mononuclear cells (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TAP2 Gene



Protein tissue co-expression partners for TAP2 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TAP2 Gene:

TAP2

SOURCE GeneReport for Unigene cluster for TAP2 Gene:

Hs.502
genes like me logo Genes that share expression patterns with TAP2: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TAP2 Gene

Orthologs for TAP2 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TAP2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TAP2 34
  • 98.74 (n)
-- 35
  • 92 (a)
OneToMany
dog
(Canis familiaris)
Mammalia TAP2 34 35
  • 82.12 (n)
cow
(Bos Taurus)
Mammalia TAP2 34 35
  • 80.58 (n)
-- 35
  • 75 (a)
ManyToMany
mouse
(Mus musculus)
Mammalia Tap2 34 16 35
  • 79.57 (n)
rat
(Rattus norvegicus)
Mammalia Tap2 34
  • 79.17 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 65 (a)
ManyToMany
-- 35
  • 61 (a)
ManyToMany
-- 35
  • 59 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 53 (a)
OneToMany
chicken
(Gallus gallus)
Aves TAP2 34 35
  • 59.58 (n)
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 51 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia tap2 34
  • 55.11 (n)
zebrafish
(Danio rerio)
Actinopterygii abcb3l1 34 35
  • 54.72 (n)
si:dkey-57h18.2 35
  • 36 (a)
ManyToMany
worm
(Caenorhabditis elegans)
Secernentea haf-2 35
  • 28 (a)
ManyToMany
haf-9 35
  • 28 (a)
ManyToMany
haf-4 35
  • 27 (a)
ManyToMany
haf-8 35
  • 27 (a)
ManyToMany
haf-7 35
  • 23 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes MDL1 35
  • 24 (a)
ManyToMany
MDL2 35
  • 24 (a)
ManyToMany
barley
(Hordeum vulgare)
Liliopsida Hv.7271 34
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 29 (a)
ManyToMany
CSA.2338 35
  • 28 (a)
ManyToMany
Species where no ortholog for TAP2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TAP2 Gene

ENSEMBL:
Gene Tree for TAP2 (if available)
TreeFam:
Gene Tree for TAP2 (if available)

Paralogs for TAP2 Gene

Paralogs for TAP2 Gene

genes like me logo Genes that share paralogs with TAP2: view

Variants for TAP2 Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for TAP2 Gene

TAP2_HUMAN-Q03519
4 common alleles are officially recognized: TAP2*01:01 (TAP2A or PSF2A or RING11A), TAP2*01:02 (TAP2E), TAP2*01:03 (TAP2F), and TAP2*02:01 (TAP2B or PSF2B or RING11B). Other relatively common alleles have been identified: TAP2*01D, TAP2*01E, TAP2*01F, TAP2*01G, TAP2*01H, TAP2*02B, TAP2*02C (TAP2*02:02), TAP2*02D, TAP2*02E, TAP2*02F, TAP2*03A and TAP2*04A. The sequence shown is that of TAP2*01:01.
TAP2_HUMAN-Q03519
The allele TAP2*Bky2 is commonly found only in the Japanese population. It may be associated with susceptibility to Sjoegren syndrome, an autoimmune disorder characterized by abnormal dryness of the conjunctiva, cornea and mouth due to exocrine glands dysfunction.

Sequence variations from dbSNP and Humsavar for TAP2 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1800454 Benign 32,832,635(-) TGCTC(A/G)TAAGG reference, missense
rs241447 Benign 32,828,974(-) TGCAG(A/G)CAGTT intron-variant, reference, missense
rs241448 Benign 32,828,908(-) AGCTC(C/T)AGGAG intron-variant, reference, stop-gained, stop-lost
rs1015166 -- 32,830,954(+) TTGGA(C/T)GGAAT intron-variant
rs1042116 -- 32,830,771(-) AGCAA(C/T)GTGGG reference, synonymous-codon

Structural Variations from Database of Genomic Variants (DGV) for TAP2 Gene

Variant ID Type Subtype PubMed ID
nsv830633 CNV loss 17160897
nsv522573 CNV loss 19592680
nsv511120 OTHER complex 20534489
nsv462891 CNV loss 19166990
nsv1119076 CNV deletion 24896259
nsv1112900 CNV deletion 24896259
nsv1073969 CNV deletion 25765185
esv3567580 CNV deletion 23714750
esv33465 CNV loss 17666407
esv32583 CNV loss 17666407
esv3083127 CNV deletion 24192839
esv2731874 CNV deletion 23290073
esv2731872 CNV deletion 23290073
esv2660966 CNV deletion 23128226
esv1707688 CNV deletion 17803354

Variation tolerance for TAP2 Gene

Residual Variation Intolerance Score: 78.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 10.18; 90.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TAP2 Gene

Human Gene Mutation Database (HGMD)
TAP2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
TAP2

Disorders for TAP2 Gene

MalaCards: The human disease database

(9) MalaCards diseases for TAP2 Gene - From: OMIM, ClinVar, Orphanet, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
bare lymphocyte syndrome, type i
  • bare lymphocyte syndrome, type i, due to tap2 deficiency
herpes simplex
  • herpesvirus hominis disease
spondylitis
cardiac sarcoidosis
posterior uveal melanoma
  • medium/large size posterior uveal melanoma
- elite association - COSMIC cancer census association via MalaCards
Search TAP2 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

TAP2_HUMAN
  • Bare lymphocyte syndrome 1 (BLS1) [MIM:604571]: A HLA class I deficiency. Contrary to bare lymphocyte syndromes type 2 and type 3, which are characterized by early-onset severe combined immunodeficiency, class I antigen deficiencies are not accompanied by particular pathologic manifestations during the first years of life. Systemic infections have not been described. Chronic bacterial infections, often beginning in the first decade of life, are restricted to the respiratory tract. {ECO:0000269 PubMed:7517574}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for TAP2

Genetic Association Database (GAD)
TAP2
Human Genome Epidemiology (HuGE) Navigator
TAP2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TAP2
genes like me logo Genes that share disorders with TAP2: view

No data available for Genatlas for TAP2 Gene

Publications for TAP2 Gene

  1. Genotyping TAP2 variants in North American Caucasians, Brazilians, and Africans. (PMID: 11294565) Tang J. … Kaslow R.A. (Genes Immun. 2001) 3 4 22 46 64
  2. Association of a new allele of the TAP2 gene, TAP2*Bky2 (Val577), with susceptibility to Sjogren's syndrome. (PMID: 9324024) Kumagai S. … Saji H. (Arthritis Rheum. 1997) 3 4 22 46 64
  3. Polymorphisms in the TAP2 gene and their association with rheumatoid arthritis. (PMID: 8162639) Singal D.P. … D'Souza M. (Clin. Exp. Rheumatol. 1994) 3 4 22 46 64
  4. Two putative subunits of a peptide pump encoded in the human major histocompatibility complex class II region. (PMID: 1946428) Bahram S. … Spies T. (Proc. Natl. Acad. Sci. U.S.A. 1991) 2 3 4 22 64
  5. Variation in the ATP-binding cassette transporter 2 gene is a separate risk factor for systemic lupus erythematosus within the MHC. (PMID: 19387463) Ramos P.S. … Moser K.L. (Genes Immun. 2009) 3 22 46 64

Products for TAP2 Gene

Sources for TAP2 Gene

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